High-level resistance to colistin mediated by various mutations in the crrB gene among carbapenemase-producing klebsiella pneumoniae

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 11, 2017, Pages

  Jayol, Aurélie ^a,b,c   Nordmann, Patrice ^a,d   Brink, Adrian ^e   Villegas, Maria Virginia ^f   Dubois, Véronique ^b,c   Poirela, Laurent ^a  

^a UNIVERSITY OF FRIBOURG   (Switzerland)

^b BORDEAUX UNIVERSITY HOSPITAL   (France)

^c UNIVERSITÉ DE BORDEAUX   (France)

^d LAUSANNE UNIVERSITY HOSPITAL   (Switzerland)

^e MILPARK HOSPITAL   (South Africa)

^f CENTRO INTERNACIONAL DE ENTRENAMIENTO E INVESTIGACIONES MÉDICAS CIDEIM   (Colombia)

Author keywords

CrrAB; Klebsiella pneumoniae; Polymyxin; Rapid polymyxin NP test; Resistance mechanisms; Susceptibility testing

Indexed keywords

COLISTIN; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; BETA-LACTAMASE KPC-2, KLEBSIELLA PNEUMONIAE; BETA-LACTAMASE NDM-1; CARBAPENEMASE;

AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENE; BACTERIAL STRAIN; BROTH DILUTION; CARBAPENEMASE PRODUCING KLEBSIELLA PNEUMONIAE; CRRA GENE; CRRB GENE; GENE MUTATION; KLEBSIELLA PNEUMONIAE; NONHUMAN; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; DRUG EFFECT; GENE EXPRESSION REGULATION; GENETIC COMPLEMENTATION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MUTATION;

AMINO ACID SUBSTITUTION; ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BETA-LACTAMASES; COLISTIN; DRUG RESISTANCE, BACTERIAL; GENE EXPRESSION REGULATION, BACTERIAL; GENETIC COMPLEMENTATION TEST; HUMANS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; MUTATION;

EID: 85032504718     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.01423-17     Document Type: Article

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