Widespread optogenetic expression in macaque cortex obtained with MR-guided, convection enhanced delivery (CED) of AAV vector to the thalamus

Journal of Neuroscience Methods

Volumn 293, Issue , 2018, Pages 347-358

  Yazdan Shahmorad, Azadeh ^a   Tian, Nan ^a   Kharazia, Viktor ^a   Samaranch, Lluis ^b   Kells, Adrian ^a   Bringas, John ^b   He, Jiwei ^a   Bankiewicz, Krystof ^b   Sabes, Philip N ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

Non human primates; Opsin expression; Optogenetics; Sensorimotor cortex; Thalamo cortical pathway; Viral vector delivery

Indexed keywords

ADENO ASSOCIATED VIRUS VECTOR; CHANNELRHODOPSIN 2; OPSIN; UNCLASSIFIED DRUG; YELLOW FLUORESCENT PROTEIN; BACTERIAL PROTEIN; CHANNELRHODOPSIN; PHOTOPROTEIN; YELLOW FLUORESCENT PROTEIN, BACTERIA;

ADENO ASSOCIATED VIRUS; ANIMAL CELL; ARTICLE; BRAIN CORTEX; BRAIN ELECTROPHYSIOLOGY; BRAIN SIZE; COMPARATIVE STUDY; CONVECTION ENHANCED DELIVERY; ELECTROPHYSIOLOGICAL PROCEDURES; FEMALE; GENE EXPRESSION; IMMUNOFLUORESCENCE; IMMUNOHISTOCHEMISTRY; MALE; MOLECULAR WEIGHT; NERVE FIBER TRANSPORT; NEUROFILAMENT; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; OPTOGENETICS; PHOTOSTIMULATION; PRIORITY JOURNAL; PROMOTER REGION; PYRAMIDAL NERVE CELL; RHESUS MONKEY; THALAMUS; VIRAL GENE DELIVERY SYSTEM; ADMINISTRATION AND DOSAGE; ANIMAL; ANIMAL MODEL; CYTOLOGY; DEPENDOPARVOVIRUS; DIAGNOSTIC IMAGING; EPILUMINESCENCE MICROSCOPY; GENE VECTOR; GENETICS; METABOLISM; NERVE TRACT; PHYSIOLOGY; PROCEDURES; THERMODYNAMICS; THREE DIMENSIONAL IMAGING;

ANIMALS; BACTERIAL PROTEINS; CEREBRAL CORTEX; CHANNELRHODOPSINS; CONVECTION; DEPENDOVIRUS; DERMOSCOPY; FEMALE; GENETIC VECTORS; IMAGING, THREE-DIMENSIONAL; IMMUNOHISTOCHEMISTRY; LUMINESCENT PROTEINS; MACACA MULATTA; MAGNETIC RESONANCE IMAGING; MALE; MODELS, ANIMAL; NEURAL PATHWAYS; OPTOGENETICS; PHOTIC STIMULATION; THALAMUS;

EID: 85032265490     PISSN: 01650270     EISSN: 1872678X     Source Type: Journal    
DOI: 10.1016/j.jneumeth.2017.10.009     Document Type: Article

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