-
1
-
-
84963520567
-
The amyloid hypothesis of Alzheimer's disease at 25 years
-
Selkoe, D.J., Hardy, J., The amyloid hypothesis of Alzheimer's disease at 25 years. EMBO Mol. Med. 8 (2016), 595–608.
-
(2016)
EMBO Mol. Med.
, vol.8
, pp. 595-608
-
-
Selkoe, D.J.1
Hardy, J.2
-
2
-
-
84937404126
-
Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease
-
Friedman, L.G., Qureshi, Y.H., Yu, W.H., Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease. Neurotherapeutics 12 (2015), 94–108.
-
(2015)
Neurotherapeutics
, vol.12
, pp. 94-108
-
-
Friedman, L.G.1
Qureshi, Y.H.2
Yu, W.H.3
-
3
-
-
84883499836
-
Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy
-
Fogel, A.I., Dlouhy, B.J., Wang, C., Ryu, S.W., Neutzner, A., Hasson, S.A., Sideris, D.P., Abeliovich, H., Youle, R.J., Role of membrane association and Atg14-dependent phosphorylation in beclin-1-mediated autophagy. Mol. Cell. Biol. 33 (2013), 3675–3688.
-
(2013)
Mol. Cell. Biol.
, vol.33
, pp. 3675-3688
-
-
Fogel, A.I.1
Dlouhy, B.J.2
Wang, C.3
Ryu, S.W.4
Neutzner, A.5
Hasson, S.A.6
Sideris, D.P.7
Abeliovich, H.8
Youle, R.J.9
-
4
-
-
45749114895
-
The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice
-
Pickford, F., Masliah, E., Britschgi, M., Lucin, K., Narasimhan, R., Jaeger, P.A., Small, S., Spencer, B., Rockenstein, E., Levine, B., Wyss-Coray, T., The autophagy-related protein beclin 1 shows reduced expression in early Alzheimer disease and regulates amyloid beta accumulation in mice. J. Clin. Invest. 118 (2008), 2190–2199.
-
(2008)
J. Clin. Invest.
, vol.118
, pp. 2190-2199
-
-
Pickford, F.1
Masliah, E.2
Britschgi, M.3
Lucin, K.4
Narasimhan, R.5
Jaeger, P.A.6
Small, S.7
Spencer, B.8
Rockenstein, E.9
Levine, B.10
Wyss-Coray, T.11
-
5
-
-
79953230490
-
Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
-
Zhu, Y., Zhao, L., Liu, L., Gao, P., Tian, W., Wang, X., Jin, H., Xu, H., Chen, Q., Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 1 (2010), 468–477.
-
(2010)
Protein Cell
, vol.1
, pp. 468-477
-
-
Zhu, Y.1
Zhao, L.2
Liu, L.3
Gao, P.4
Tian, W.5
Wang, X.6
Jin, H.7
Xu, H.8
Chen, Q.9
-
6
-
-
79955964504
-
Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
-
Rohn, T.T., Wirawan, E., Brown, R.J., Harris, J.R., Masliah, E., Vandenabeele, P., Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol. Dis. 43 (2011), 68–78.
-
(2011)
Neurobiol. Dis.
, vol.43
, pp. 68-78
-
-
Rohn, T.T.1
Wirawan, E.2
Brown, R.J.3
Harris, J.R.4
Masliah, E.5
Vandenabeele, P.6
-
7
-
-
78649251041
-
The in vitro cleavage of the hAtg proteins by cell death proteases
-
Norman, J.M., Cohen, G.M., Bampton, E.T., The in vitro cleavage of the hAtg proteins by cell death proteases. Autophagy 6 (2010), 1042–1056.
-
(2010)
Autophagy
, vol.6
, pp. 1042-1056
-
-
Norman, J.M.1
Cohen, G.M.2
Bampton, E.T.3
-
8
-
-
79956144655
-
Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1
-
Li, H., Wang, P., Sun, Q., Ding, W.X., Yin, X.M., Sobol, R.W., Stolz, D.B., Yu, J., Zhang, L., Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Res. 71 (2011), 3625–3634.
-
(2011)
Cancer Res.
, vol.71
, pp. 3625-3634
-
-
Li, H.1
Wang, P.2
Sun, Q.3
Ding, W.X.4
Yin, X.M.5
Sobol, R.W.6
Stolz, D.B.7
Yu, J.8
Zhang, L.9
-
9
-
-
78649636176
-
Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria
-
Wirawan, E., Vande Walle, L., Kersse, K., Cornelis, S., Claerhout, S., Vanoverberghe, I., Roelandt, R., De Rycke, R., Verspurten, J., Declercq, W., Agostinis, P., Vanden Berghe, T., Lippens, S., Vandenabeele, P., Caspase-mediated cleavage of Beclin-1 inactivates Beclin-1-induced autophagy and enhances apoptosis by promoting the release of proapoptotic factors from mitochondria. Cell Death Dis., 1, 2010, e18.
-
(2010)
Cell Death Dis.
, vol.1
, pp. e18
-
-
Wirawan, E.1
Vande Walle, L.2
Kersse, K.3
Cornelis, S.4
Claerhout, S.5
Vanoverberghe, I.6
Roelandt, R.7
De Rycke, R.8
Verspurten, J.9
Declercq, W.10
Agostinis, P.11
Vanden Berghe, T.12
Lippens, S.13
Vandenabeele, P.14
-
10
-
-
74249109983
-
Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
-
Luo, S., Rubinsztein, D.C., Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ. 17 (2010), 268–277.
-
(2010)
Cell Death Differ.
, vol.17
, pp. 268-277
-
-
Luo, S.1
Rubinsztein, D.C.2
-
11
-
-
49049096562
-
Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
-
Boland, B., Kumar, A., Lee, S., Platt, F.M., Wegiel, J., Yu, W.H., Nixon, R.A., Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 28 (2008), 6926–6937.
-
(2008)
J. Neurosci.
, vol.28
, pp. 6926-6937
-
-
Boland, B.1
Kumar, A.2
Lee, S.3
Platt, F.M.4
Wegiel, J.5
Yu, W.H.6
Nixon, R.A.7
-
12
-
-
84899688008
-
Stimulation of autophagy prevents amyloid-beta peptide-induced neuritic degeneration in PC12 cells
-
Yang, Y., Chen, S., Zhang, J., Li, C., Sun, Y., Zhang, L., Zheng, X., Stimulation of autophagy prevents amyloid-beta peptide-induced neuritic degeneration in PC12 cells. J. Alzheimer's Dis 40 (2014), 929–939.
-
(2014)
J. Alzheimer's Dis
, vol.40
, pp. 929-939
-
-
Yang, Y.1
Chen, S.2
Zhang, J.3
Li, C.4
Sun, Y.5
Zhang, L.6
Zheng, X.7
-
13
-
-
84928434158
-
Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux
-
Yang, Y., Zhang, L.H., Yang, B.X., Tian, J.K., Zhang, L., Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux. J. Cell. Mol. Med. 19 (2015), 1055–1064.
-
(2015)
J. Cell. Mol. Med.
, vol.19
, pp. 1055-1064
-
-
Yang, Y.1
Zhang, L.H.2
Yang, B.X.3
Tian, J.K.4
Zhang, L.5
-
14
-
-
84863229959
-
Neuronal autophagy and neurodegenerative diseases
-
Son, J.H., Shim, J.H., Kim, K.H., Ha, J.Y., Han, J.Y., Neuronal autophagy and neurodegenerative diseases. Exp. Mol. Med. 44 (2012), 89–98.
-
(2012)
Exp. Mol. Med.
, vol.44
, pp. 89-98
-
-
Son, J.H.1
Shim, J.H.2
Kim, K.H.3
Ha, J.Y.4
Han, J.Y.5
-
15
-
-
77956215864
-
Regulation of amyloid precursor protein processing by the Beclin 1 complex
-
Jaeger, P.A., Pickford, F., Sun, C.H., Lucin, K.M., Masliah, E., Wyss-Coray, T., Regulation of amyloid precursor protein processing by the Beclin 1 complex. PLoS One, 5, 2010, e11102.
-
(2010)
PLoS One
, vol.5
, pp. e11102
-
-
Jaeger, P.A.1
Pickford, F.2
Sun, C.H.3
Lucin, K.M.4
Masliah, E.5
Wyss-Coray, T.6
-
16
-
-
84863011717
-
Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction
-
Xing, S., Zhang, Y., Li, J., Zhang, J., Li, Y., Dang, C., Li, C., Fan, Y., Yu, J., Pei, Z., Zeng, J., Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction. Autophagy 8 (2012), 63–76.
-
(2012)
Autophagy
, vol.8
, pp. 63-76
-
-
Xing, S.1
Zhang, Y.2
Li, J.3
Zhang, J.4
Li, Y.5
Dang, C.6
Li, C.7
Fan, Y.8
Yu, J.9
Pei, Z.10
Zeng, J.11
-
17
-
-
84930226935
-
Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth
-
Sun, T., Li, X., Zhang, P., Chen, W.D., Zhang, H.L., Li, D.D., Deng, R., Qian, X.J., Jiao, L., Ji, J., Li, Y.T., Wu, R.Y., Yu, Y., Feng, G.K., Zhu, X.F., Acetylation of Beclin 1 inhibits autophagosome maturation and promotes tumour growth. Nat. Commun., 6, 2015, 7215.
-
(2015)
Nat. Commun.
, vol.6
, pp. 7215
-
-
Sun, T.1
Li, X.2
Zhang, P.3
Chen, W.D.4
Zhang, H.L.5
Li, D.D.6
Deng, R.7
Qian, X.J.8
Jiao, L.9
Ji, J.10
Li, Y.T.11
Wu, R.Y.12
Yu, Y.13
Feng, G.K.14
Zhu, X.F.15
-
18
-
-
84884262668
-
EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance
-
Wei, Y., Zou, Z., Becker, N., Anderson, M., Sumpter, R., Xiao, G., Kinch, L., Koduru, P., Christudass, C.S., Veltri, R.W., Grishin, N.V., Peyton, M., Minna, J., Bhagat, G., Levine, B., EGFR-mediated Beclin 1 phosphorylation in autophagy suppression, tumor progression, and tumor chemoresistance. Cell 154 (2013), 1269–1284.
-
(2013)
Cell
, vol.154
, pp. 1269-1284
-
-
Wei, Y.1
Zou, Z.2
Becker, N.3
Anderson, M.4
Sumpter, R.5
Xiao, G.6
Kinch, L.7
Koduru, P.8
Christudass, C.S.9
Veltri, R.W.10
Grishin, N.V.11
Peyton, M.12
Minna, J.13
Bhagat, G.14
Levine, B.15
-
19
-
-
0035870257
-
Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
-
Liang, X.H., Yu, J., Brown, K., Levine, B., Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res. 61 (2001), 3443–3449.
-
(2001)
Cancer Res.
, vol.61
, pp. 3443-3449
-
-
Liang, X.H.1
Yu, J.2
Brown, K.3
Levine, B.4
-
20
-
-
77950252174
-
Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
-
Djavaheri-Mergny, M., Maiuri, M.C., Kroemer, G., Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29 (2010), 1717–1719.
-
(2010)
Oncogene
, vol.29
, pp. 1717-1719
-
-
Djavaheri-Mergny, M.1
Maiuri, M.C.2
Kroemer, G.3
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