메뉴 건너뛰기




Volumn 661, Issue , 2017, Pages 63-70

The cytoplasmic nuclear shuttling of Beclin 1 in neurons with Alzheimer's disease-like injury

Author keywords

Alzheimer's disease; Beclin 1; Cortical neuron; Nuclei; PC12 cells

Indexed keywords

AMYLOID BETA PROTEIN[1-42]; BECLIN 1; CASPASE 3; CASPASE 3 INHIBITOR; CASPASE INHIBITOR; AMYLOID BETA PROTEIN; AMYLOID PRECURSOR PROTEIN; APOPTOSIS REGULATORY PROTEIN; CASP3 PROTEIN, HUMAN;

EID: 85030315878     PISSN: 03043940     EISSN: 18727972     Source Type: Journal    
DOI: 10.1016/j.neulet.2017.09.055     Document Type: Article
Times cited : (10)

References (20)
  • 1
    • 84963520567 scopus 로고    scopus 로고
    • The amyloid hypothesis of Alzheimer's disease at 25 years
    • Selkoe, D.J., Hardy, J., The amyloid hypothesis of Alzheimer's disease at 25 years. EMBO Mol. Med. 8 (2016), 595–608.
    • (2016) EMBO Mol. Med. , vol.8 , pp. 595-608
    • Selkoe, D.J.1    Hardy, J.2
  • 2
    • 84937404126 scopus 로고    scopus 로고
    • Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease
    • Friedman, L.G., Qureshi, Y.H., Yu, W.H., Promoting autophagic clearance: viable therapeutic targets in Alzheimer's disease. Neurotherapeutics 12 (2015), 94–108.
    • (2015) Neurotherapeutics , vol.12 , pp. 94-108
    • Friedman, L.G.1    Qureshi, Y.H.2    Yu, W.H.3
  • 5
    • 79953230490 scopus 로고    scopus 로고
    • Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis
    • Zhu, Y., Zhao, L., Liu, L., Gao, P., Tian, W., Wang, X., Jin, H., Xu, H., Chen, Q., Beclin 1 cleavage by caspase-3 inactivates autophagy and promotes apoptosis. Protein Cell 1 (2010), 468–477.
    • (2010) Protein Cell , vol.1 , pp. 468-477
    • Zhu, Y.1    Zhao, L.2    Liu, L.3    Gao, P.4    Tian, W.5    Wang, X.6    Jin, H.7    Xu, H.8    Chen, Q.9
  • 6
    • 79955964504 scopus 로고    scopus 로고
    • Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain
    • Rohn, T.T., Wirawan, E., Brown, R.J., Harris, J.R., Masliah, E., Vandenabeele, P., Depletion of Beclin-1 due to proteolytic cleavage by caspases in the Alzheimer's disease brain. Neurobiol. Dis. 43 (2011), 68–78.
    • (2011) Neurobiol. Dis. , vol.43 , pp. 68-78
    • Rohn, T.T.1    Wirawan, E.2    Brown, R.J.3    Harris, J.R.4    Masliah, E.5    Vandenabeele, P.6
  • 7
    • 78649251041 scopus 로고    scopus 로고
    • The in vitro cleavage of the hAtg proteins by cell death proteases
    • Norman, J.M., Cohen, G.M., Bampton, E.T., The in vitro cleavage of the hAtg proteins by cell death proteases. Autophagy 6 (2010), 1042–1056.
    • (2010) Autophagy , vol.6 , pp. 1042-1056
    • Norman, J.M.1    Cohen, G.M.2    Bampton, E.T.3
  • 8
    • 79956144655 scopus 로고    scopus 로고
    • Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1
    • Li, H., Wang, P., Sun, Q., Ding, W.X., Yin, X.M., Sobol, R.W., Stolz, D.B., Yu, J., Zhang, L., Following cytochrome c release, autophagy is inhibited during chemotherapy-induced apoptosis by caspase 8-mediated cleavage of Beclin 1. Cancer Res. 71 (2011), 3625–3634.
    • (2011) Cancer Res. , vol.71 , pp. 3625-3634
    • Li, H.1    Wang, P.2    Sun, Q.3    Ding, W.X.4    Yin, X.M.5    Sobol, R.W.6    Stolz, D.B.7    Yu, J.8    Zhang, L.9
  • 10
    • 74249109983 scopus 로고    scopus 로고
    • Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL
    • Luo, S., Rubinsztein, D.C., Apoptosis blocks Beclin 1-dependent autophagosome synthesis: an effect rescued by Bcl-xL. Cell Death Differ. 17 (2010), 268–277.
    • (2010) Cell Death Differ. , vol.17 , pp. 268-277
    • Luo, S.1    Rubinsztein, D.C.2
  • 11
    • 49049096562 scopus 로고    scopus 로고
    • Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease
    • Boland, B., Kumar, A., Lee, S., Platt, F.M., Wegiel, J., Yu, W.H., Nixon, R.A., Autophagy induction and autophagosome clearance in neurons: relationship to autophagic pathology in Alzheimer's disease. J. Neurosci. 28 (2008), 6926–6937.
    • (2008) J. Neurosci. , vol.28 , pp. 6926-6937
    • Boland, B.1    Kumar, A.2    Lee, S.3    Platt, F.M.4    Wegiel, J.5    Yu, W.H.6    Nixon, R.A.7
  • 12
    • 84899688008 scopus 로고    scopus 로고
    • Stimulation of autophagy prevents amyloid-beta peptide-induced neuritic degeneration in PC12 cells
    • Yang, Y., Chen, S., Zhang, J., Li, C., Sun, Y., Zhang, L., Zheng, X., Stimulation of autophagy prevents amyloid-beta peptide-induced neuritic degeneration in PC12 cells. J. Alzheimer's Dis 40 (2014), 929–939.
    • (2014) J. Alzheimer's Dis , vol.40 , pp. 929-939
    • Yang, Y.1    Chen, S.2    Zhang, J.3    Li, C.4    Sun, Y.5    Zhang, L.6    Zheng, X.7
  • 13
    • 84928434158 scopus 로고    scopus 로고
    • Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux
    • Yang, Y., Zhang, L.H., Yang, B.X., Tian, J.K., Zhang, L., Aurantiamide acetate suppresses the growth of malignant gliomas in vitro and in vivo by inhibiting autophagic flux. J. Cell. Mol. Med. 19 (2015), 1055–1064.
    • (2015) J. Cell. Mol. Med. , vol.19 , pp. 1055-1064
    • Yang, Y.1    Zhang, L.H.2    Yang, B.X.3    Tian, J.K.4    Zhang, L.5
  • 14
  • 16
    • 84863011717 scopus 로고    scopus 로고
    • Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction
    • Xing, S., Zhang, Y., Li, J., Zhang, J., Li, Y., Dang, C., Li, C., Fan, Y., Yu, J., Pei, Z., Zeng, J., Beclin 1 knockdown inhibits autophagic activation and prevents the secondary neurodegenerative damage in the ipsilateral thalamus following focal cerebral infarction. Autophagy 8 (2012), 63–76.
    • (2012) Autophagy , vol.8 , pp. 63-76
    • Xing, S.1    Zhang, Y.2    Li, J.3    Zhang, J.4    Li, Y.5    Dang, C.6    Li, C.7    Fan, Y.8    Yu, J.9    Pei, Z.10    Zeng, J.11
  • 19
    • 0035870257 scopus 로고    scopus 로고
    • Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function
    • Liang, X.H., Yu, J., Brown, K., Levine, B., Beclin 1 contains a leucine-rich nuclear export signal that is required for its autophagy and tumor suppressor function. Cancer Res. 61 (2001), 3443–3449.
    • (2001) Cancer Res. , vol.61 , pp. 3443-3449
    • Liang, X.H.1    Yu, J.2    Brown, K.3    Levine, B.4
  • 20
    • 77950252174 scopus 로고    scopus 로고
    • Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1
    • Djavaheri-Mergny, M., Maiuri, M.C., Kroemer, G., Cross talk between apoptosis and autophagy by caspase-mediated cleavage of Beclin 1. Oncogene 29 (2010), 1717–1719.
    • (2010) Oncogene , vol.29 , pp. 1717-1719
    • Djavaheri-Mergny, M.1    Maiuri, M.C.2    Kroemer, G.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.