Emergence of plasmid-mediated fosfomycin-resistance genes among Escherichia coli isolates, France

Emerging Infectious Diseases

Volumn 23, Issue 9, 2017, Pages 1564-1567

  Benzerara, Yahia ^a   Gallah, Salah ^a   Hommeril, Baptiste ^a   Genel, Nathalie ^b   Decré, Dominique ^a,b   Rottman, Martin ^c,d   Arlet, Guillaume ^a,b  

^a ASSISTANCE PUBLIQUE HÔPITAUX DE PARIS   (France)

^b SORBONNE UNIVERSITÉ   (France)

^c RAYMOND POINCARÉ HOSPITAL   (France)

^d LABORATOIRE DES SCIENCES DU CLIMAT ET DE L ENVIRONNEMENT   (France)

Author keywords

[No Author keywords available]

Indexed keywords

BETA LACTAMASE CTX M; FOSFOMYCIN; ANTIINFECTIVE AGENT; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN; FOSA(3) PROTEIN, E COLI; FOSCARNET; ISOENZYME;

ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL STRAIN; BACTERIUM ISOLATE; DISK DIFFUSION; ESCHERICHIA COLI; GENE SEQUENCE; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; PHENOTYPE; PLASMID; POLYMERASE CHAIN REACTION; CHEMISTRY; DRUG EFFECTS; ENZYMOLOGY; ESCHERICHIA COLI INFECTION; FRANCE; GENE EXPRESSION; GENETICS; HUMAN; ISOLATION AND PURIFICATION; METABOLISM; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE; PREVALENCE;

ANTI-BACTERIAL AGENTS; BETA-LACTAMASES; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ESCHERICHIA COLI; ESCHERICHIA COLI INFECTIONS; ESCHERICHIA COLI PROTEINS; FOSCARNET; FOSFOMYCIN; FRANCE; GENE EXPRESSION; HUMANS; ISOENZYMES; MICROBIAL SENSITIVITY TESTS; PLASMIDS; PREVALENCE;

EID: 85030266203     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid2309.170560     Document Type: Article

References (15)

1. Société de Pathologie Infectieuse de Langue Française. Diagnostic et antibiothérapie des infections urinaires bactériennes communautaires de l’adulte [cited 2017 Jun 21]. http://www.infectiologie.com/UserFiles/File/spilf/recos/infections-urinaires-spilf.pdf
2. Agence Nationale de Sécurité du Médicaments. Etude d’utilisation de la nitrofurantoïne en France—période mars 2012–février 2015 [cited 2017 Jun 21]. http://ansm.sante.fr/var/ansm_site/storage/original/application/d807c8e39321445201911cf314263f07.pdf
3. Kaye KS, Gales AC, Dubourg G. Old antibiotics for multidrug-resistant pathogens: from in vitro activity to clinical outcomes. Int J Antimicrob Agents. 2017;49:542–8. http://dx.doi.org/10.1016/j.ijantimicag.2016.11.020
4. Castañeda-García A, Blázquez J, Rodríguez-Rojas A. Molecular mechanisms and clinical impact of acquired and intrinsic fosfomycin resistance. Antibiotics (Basel). 2013;2:217–36. http://dx.doi.org/10.3390/antibiotics2020217
5. Ho PL, Chan J, Lo WU, Lai EL, Cheung YY, Lau TC, et al. Prevalence and molecular epidemiology of plasmid-mediated fosfomycin resistance genes among blood and urinary Escherichia coli isolates. J Med Microbiol. 2013;62:1707–13. http://dx.doi.org/10.1099/jmm.0.062653-0
6. Lee SY, Park YJ, Yu JK, Jung S, Kim Y, Jeong SH, et al. Prevalence of acquired fosfomycin resistance among extended-spectrum β-lactamase-producing Escherichia coli and Klebsiella pneumoniae clinical isolates in Korea and IS26-composite transposon surrounding fosA3. J Antimicrob Chemother. 2012;67:2843–7. http://dx.doi.org/10.1093/jac/dks319
7. Wachino J, Yamane K, Suzuki S, Kimura K, Arakawa Y. Prevalence of fosfomycin resistance among CTX-M-producing Escherichia coli clinical isolates in Japan and identification of novel plasmid-mediated fosfomycin-modifying enzymes. Antimicrob Agents Chemother. 2010;54:3061–4. http://dx.doi.org/10.1128/AAC.01834-09
8. Hou J, Huang X, Deng Y, He L, Yang T, Zeng Z, et al. Dissemination of the fosfomycin resistance gene fosA3 with CTX-M β-lactamase genes and rmtB carried on IncFII plasmids among Escherichia coli isolates from pets in China. Antimicrob Agents Chemother. 2012;56:2135–8. http://dx.doi.org/10.1128/AAC.05104-11
9. Chan J, Lo WU, Chow KH, Lai EL, Law PY, Ho PL. Clonal diversity of Escherichia coli isolates carrying plasmid-mediated fosfomycin resistance gene fosA3 from livestock and other animals. Antimicrob Agents Chemother. 2014;58:5638–9. http://dx.doi.org/10.1128/AAC.02700-14
10. Hou J, Yang X, Zeng Z, Lv L, Yang T, Lin D, et al. Detection of the plasmid-encoded fosfomycin resistance gene fosA3 in Escherichia coli of food-animal origin. J Antimicrob Chemother. 2013;68:766–70. http://dx.doi.org/10.1093/jac/dks465
11. Mendes AC, Rodrigues C, Pires J, Amorim J, Ramos MH, Novais Â, et al. Importation of fosfomycin resistance fosA3 gene to Europe. Emerg Infect Dis. 2016;22:346–8. http://dx.doi.org/10.3201/eid2202.151301
12. Nakamura G, Wachino J, Sato N, Kimura K, Yamada K, Jin W, et al. Practical agar-based disk potentiation test for detection of fosfomycin-nonsusceptible Escherichia coli clinical isolates producing glutathione S-transferases. J Clin Microbiol. 2014;52:3175–9. http://dx.doi.org/10.1128/JCM.01094-14
13. Ma Y, Xu X, Guo Q, Wang P, Wang W, Wang M. Characterization of fosA5, a new plasmid-mediated fosfomycin resistance gene in Escherichia coli. Lett Appl Microbiol. 2015;60:259–64. http://dx.doi.org/10.1111/lam.12366
14. Compain F, Poisson A, Le Hello S, Branger C, Weill FX, Arlet G, et al. Targeting relaxase genes for classification of the predominant plasmids in Enterobacteriaceae. Int J Med Microbiol. 2014; 304:236–42. http://dx.doi.org/10.1016/j.ijmm.2013.09.009
15. Al-Tawfiq JA, Laxminarayan R, Mendelson M. How should we respond to the emergence of plasmid-mediated colistin resistance in humans and animals? Int J Infect Dis. 2017;54:77–84. http://dx.doi.org/10.1016/j.ijid.2016.11.415