REducing STEroids in Relapsing Nephrotic syndrome: The RESTERN study-protocol of a national, double-blind, randomised, placebo-controlled, non-inferiority intervention study

BMJ Open

Volumn 7, Issue 9, 2017, Pages

  Schijvens, A M ^a   Dorresteijn, E M ^b   Roeleveld, N ^a   Ter Heine, R ^a   Van Wijk, J A E ^c   Bouts, A H M ^d   Keijzer Veen, M G ^e   Van De Kar, N C A J ^a   Van Den Heuvel, L P W J ^a,f   Schreuder, M F ^a  

^a RADBOUD UNIVERSITY MEDICAL CENTER   (Netherlands)

^b SOPHIA CHILDREN S HOSPITAL   (Netherlands)

^c VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^d EMMA CHILDREN S HOSPITAL   (Netherlands)

^e UNIVERSITY MEDICAL CENTER UTRECHT   (Netherlands)

^f UNIVERSITY HOSPITALS LEUVEN   (Belgium)

Author keywords

Corticosteroids; Nephrotic syndrome; Pediatrics; Randomised clinical trial

Indexed keywords

CORTICOSTEROID; CYCLOSPORIN A; LEVAMISOLE; MYCOPHENOLATE MOFETIL; MYCOPHENOLIC ACID; PLACEBO; PREDNISOLONE; TACROLIMUS; STEROID;

ADOLESCENT; ADULT; ARTICLE; CHILD; CONTROLLED STUDY; CORTICOSTEROID THERAPY; DISEASE COURSE; DOUBLE BLIND PROCEDURE; DRUG WITHDRAWAL; FEMALE; HUMAN; IMMUNOSUPPRESSIVE TREATMENT; INTERVENTION STUDY; MAINTENANCE THERAPY; MAJOR CLINICAL STUDY; MALE; NEPHROTIC SYNDROME; OUTCOME ASSESSMENT; PRACTICE GUIDELINE; RANDOMIZED CONTROLLED TRIAL; RELAPSE; RELAPSING NEPHROTIC SYNDROME; TREATMENT DURATION; CLINICAL TRIAL; DRUG MONITORING; INFANT; METHODOLOGY; MULTICENTER STUDY; NETHERLANDS; PATHOPHYSIOLOGY; PRESCHOOL CHILD; PROCEDURES; RECURRENT DISEASE; SECONDARY PREVENTION; TREATMENT OUTCOME;

ADOLESCENT; CHILD; CHILD, PRESCHOOL; DOUBLE-BLIND METHOD; DRUG MONITORING; FEMALE; HUMANS; INFANT; MALE; NEPHROTIC SYNDROME; NETHERLANDS; PREDNISOLONE; RECURRENCE; RESEARCH DESIGN; SECONDARY PREVENTION; STEROIDS; TREATMENT OUTCOME;

EID: 85030214680     PISSN: None     EISSN: 20446055     Source Type: Journal    
DOI: 10.1136/bmjopen-2017-018148     Document Type: Article

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