Hsp-27 levels and thrombus burden relate to clinical outcomes in patients with ST-segment elevation myocardial infarction

Oncotarget

Volumn 8, Issue 43, 2017, Pages 73733-73744

  Tian, Maozhou ^a   Zhu, Lingmin ^a   Lin, Hongyang ^a   Lin, Qiaoyan ^a   Huang, Peng ^a   Yu, Xiao ^a   Jing, Yanyan ^a  

^a YANTAI YUHUANGDING HOSPITAL   (China)

Author keywords

Hsp 27; Major adverse cardiovascular event; STEMI; Thrombus burden

Indexed keywords

HEAT SHOCK PROTEIN 27;

ADULT; ARTICLE; CHINA; CONTROLLED STUDY; DIAGNOSTIC VALUE; DISEASE ASSOCIATION; DISEASE FREE SURVIVAL; FEMALE; HEMATOLOGICAL PARAMETERS; HIGH THROMBUS BURDEN; HUMAN; INCIDENCE; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; PROSPECTIVE STUDY; PROTEIN BLOOD LEVEL; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; SURVIVAL RATE; SURVIVAL TIME; SYMPTOM; TREATMENT OUTCOME;

EID: 85030105718     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.17852     Document Type: Article

References (45)

1. O'Gara PT, Kushner FG, Ascheim DD, Casey DE Jr, Chung MK, de Lemos JA, Ettinger SM, Fang JC, Fesmire FM, Franklin BA, Granger CB, Krumholz HM, Linderbaum JA, et al, and American College of Emergency Physicians, and Society for Cardiovascular Angiography and Interventions. 2013 ACCF/AHA guideline for the management of STelevation myocardial infarction: a report of the American College of Cardiology Foundation/American Heart Association Task Force on Practice Guidelines. J Am Coll Cardiol. 2013; 61:e78-140.
2. Yip HK, Chen MC, Chang HW, Hang CL, Hsieh YK, Fang CY, Wu CJ. Angiographic morphologic features of infarct-related arteries and timely reperfusion in acute myocardial infarction: predictors of slow-flow and noreflow phenomenon. Chest. 2002; 122:1322-32.
3. Grines CL, Bonow RO, Casey DE Jr, Gardner TJ, Lockhart PB, Moliterno DJ, O'Gara P, Whitlow P, and American Heart Association, and American College of Cardiology, and Society for Cardiovascular Angiography and Interventions, and American College of Surgeons, and American Dental Association, and American College of Physicians. Prevention of premature discontinuation of dual antiplatelet therapy in patients with coronary artery stents: a science advisory from the American Heart Association, American College of Cardiology, Society for Cardiovascular Angiography and Interventions, American College of Surgeons, and American Dental Association, with representation from the American College of Physicians. J Am Coll Cardiol. 2007; 49:734-39.
4. Kim SW, Hong YJ, Mintz GS, Lee SY, Doh JH, Lim SH, Kang HJ, Rha SW, Kim JS, Lee WS, Oh SJ, Lee S, Hahn JY, et al. Relation of ruptured plaque culprit lesion phenotype and outcomes in patients with ST elevation acute myocardial infarction. Am J Cardiol. 2012; 109:794-99.
5. Willis MS, Patterson C. Hold me tight: role of the heat shock protein family of chaperones in cardiac disease. Circulation. 2010; 122:1740-51.
6. Tarone G, Brancaccio M. Keep your heart in shape: molecular chaperone networks for treating heart disease. Cardiovasc Res. 2014; 102:346-61.
7. Arrigo AP, Simon S, Gibert B, Kretz-Remy C, Nivon M, Czekalla A, Guillet D, Moulin M, Diaz-Latoud C, Vicart P. Hsp27 (HspB1) and alphaB-crystallin (HspB5) as therapeutic targets. FEBS Lett. 2007; 581:3665-74.
8. Lunz W, Capettini LS, Davel AP, Munhoz CD, da Silva JF, Rossoni LV, Lemos VS, Baldo MP, Carneiro-Junior MA, Natali AJ, de Lacerda LH, Mill JG. L-NAME treatment enhances exercise-induced content of myocardial heat shock protein 72 (Hsp72) in rats. Cell Physiol Biochem. 2011; 27:479-86.
9. Katta A, Thulluri S, Manne ND, Addagarla HS, Arvapalli R, Nalabotu SK, Gadde M, Rice KM, Blough ER. Overload induced heat shock proteins (HSPs), MAPK and miRNA (miR-1 and miR133a) response in insulin-resistant skeletal muscle. Cell Physiol Biochem. 2013; 31:219-29.
10. Kabakov AE, Budagova KR, Bryantsev AL, Latchman DS. Heat shock protein 70 or heat shock protein 27 overexpressed in human endothelial cells during posthypoxic reoxygenation can protect from delayed apoptosis. Cell Stress Chaperones. 2003; 8:335-47.
11. Heidari-Bakavoli AR, Sahebkar A, Mobara N, Moohebati M, Tavallaie S, Rahsepar AA, Kazemi A, Alavi MS, Ghayour-Mobarhan M, Ferns GA. Changes in plasma level of heat shock protein 27 after acute coronary syndrome. Angiology. 2012; 63:12-16.
12. Carra S, Alberti S, Arrigo PA, Benesch JL, Benjamin IJ, Boelens W, Bartelt-Kirbach B, Brundel BJ, Buchner J, Bukau B, Carver JA, Ecroyd H, Emanuelsson C, et al. The growing world of small heat shock proteins: from structure to functions. Cell Stress Chaperones. 2017; 22:601-11.
13. Pantos C, Mourouzis I, Dimopoulos A, Markakis K, Panagiotou M, Xinaris C, Tzeis S, Kokkinos AD, Cokkinos DV. Enhanced tolerance of the rat myocardium to ischemia and reperfusion injury early after acute myocardial infarction. Basic Res Cardiol. 2007; 102:327-33.
14. Ahmed TA, Sorgdrager BJ, Cannegieter SC, van der Laarse A, Schalij MJ, Jukema W. Pre-infarction angina predicts thrombus burden in patients admitted for ST-segment elevation myocardial infarction. EuroIntervention. 2012; 7:1396-405.
15. Gibson CM, de Lemos JA, Murphy SA, Marble SJ, McCabe CH, Cannon CP, Antman EM, Braunwald E, and TIMI Study Group. Combination therapy with abciximab reduces angiographically evident thrombus in acute myocardial infarction: a TIMI 14 substudy. Circulation. 2001; 103:2550-54.
16. Hollander JM, Martin JL, Belke DD, Scott BT, Swanson E, Krishnamoorthy V, Dillmann WH. Overexpression of wild-type heat shock protein 27 and a nonphosphorylatable heat shock protein 27 mutant protects against ischemia/reperfusion injury in a transgenic mouse model. Circulation. 2004; 110:3544-52.
17. Lu XY, Chen L, Cai XL, Yang HT. Overexpression of heat shock protein 27 protects against ischaemia/reperfusion induced cardiac dysfunction via stabilization of troponin I and T. Cardiovasc Res. 2008; 79:500-08.
18. Knowlton AA, Kapadia S, Torre-Amione G, Durand JB, Bies R, Young J, Mann DL. Differential expression of heat shock proteins in normal and failing human hearts. J Mol Cell Cardiol. 1998; 30:811-18.
19. Hansson GK, Libby P. The immune response in atherosclerosis: a double-edged sword. Nat Rev Immunol. 2006; 6:508-19.
20. Park HK, Park EC, Bae SW, Park MY, Kim SW, Yoo HS, Tudev M, Ko YH, Choi YH, Kim S, Kim DI, Kim YW, Lee BB, et al. Expression of heat shock protein 27 in human atherosclerotic plaques and increased plasma level of heat shock protein 27 in patients with acute coronary syndrome. Circulation. 2006; 114:886-93.
21. Martin-Ventura JL, Duran MC, Blanco-Colio LM, Meilhac O, Leclercq A, Michel JB, Jensen ON, Hernandez-Merida S, Tuñón J, Vivanco F, Egido J. Identification by a differential proteomic approach of heat shock protein 27 as a potential marker of atherosclerosis. Circulation. 2004; 110:2216-19.
22. Rahsepar AA, Mirzaee A, Moodi F, Moohebati M, Tavallaie S, Khorashadizadeh F, Eshraghi A, Alavi MS, Zarrabi L, Sajjadian M, Amini M, Khojasteh R, Paydar R, et al. Changes in anti-heat shock protein 27 antibody and C-reactive protein levels following cardiac surgery and their association with cardiac function in patients with cardiovascular disease. Cell Stress Chaperones. 2013; 18:65-74.
23. Szerafin T, Hoetzenecker K, Hacker S, Horvath A, Pollreisz A, Arpád P, Mangold A, Wliszczak T, Dworschak M, Seitelberger R, Wolner E, Ankersmit HJ. Heat shock proteins 27, 60, 70, 90alpha, and 20S proteasome in onpump versus off-pump coronary artery bypass graft patients. Ann Thorac Surg. 2008; 85:80-87.
24. Shams S, Shafi S, Bodman-Smith K, Williams P, Mehta S, Ferns GA. Anti-heat shock protein-27 (Hsp-27) antibody levels in patients with chest pain: association with established cardiovascular risk factors. Clin Chim Acta. 2008; 395:42-46.
25. Ghayour-Mobarhan M, Saber H, Ferns GA. The potential role of heat shock protein 27 in cardiovascular disease. Clin Chim Acta. 2012; 413:15-24.
26. Tallot P, Grongnet JF, David JC. Dual perinatal and developmental expression of the small heat shock proteins [FC12]aB-crystallin and Hsp27 in different tissues of the developing piglet. Biol Neonate. 2003; 83:281-88.
27. Gaitanaki C, Konstantina S, Chrysa S, Beis I. Oxidative stress stimulates multiple MAPK signalling pathways and phosphorylation of the small HSP27 in the perfused amphibian heart. J Exp Biol. 2003; 206:2759-69.
28. Efthymiou CA, Mocanu MM, de Belleroche J, Wells DJ, Latchmann DS, Yellon DM. Heat shock protein 27 protects the heart against myocardial infarction. Basic Res Cardiol. 2004; 99:392-94.
29. Martin JL, Mestril R, Hilal-Dandan R, Brunton LL, Dillmann WH. Small heat shock proteins and protection against ischemic injury in cardiac myocytes. Circulation. 1997; 96:4343-48.
30. Martin JL, Hickey E, Weber LA, Dillmann WH, Mestril R. Influence of phosphorylation and oligomerization on the protective role of the small heat shock protein 27 in rat adult cardiomyocytes. Gene Expr. 1999; 7:349-55.
31. Ghayour-Mobarhan M, Sahebkar A, Parizadeh SM, Moohebati M, Tavallaie S, Rezakazemi-Bajestani SM, Esmaeili HA, Ferns G. Antibody titres to heat shock protein 27 are elevated in patients with acute coronary syndrome. Int J Exp Pathol. 2008; 89:209-15.
32. Pawlowska Z, Baranska P, Jerczynska H, Koziolkiewicz W, Cierniewski CS. Heat shock proteins and other components of cellular machinery for protein synthesis are up-regulated in vascular endothelial cell growth factor-activated human endothelial cells. Proteomics. 2005; 5:1217-27.
33. Lamb DJ, El-Sankary W, Ferns GA. Molecular mimicry in atherosclerosis: a role for heat shock proteins in immunisation. Atherosclerosis. 2003; 167:177-85.
34. Polanowska-Grabowska R, Gear AR. Heat-shock proteins and platelet function. Platelets. 2000; 11:6-22.
35. Butt E, Immler D, Meyer HE, Kotlyarov A, Laass K, Gaestel M. Heat shock protein 27 is a substrate of cGMPdependent protein kinase in intact human platelets: phosphorylation-induced actin polymerization caused by HSP27 mutants. J Biol Chem. 2001; 276:7108-13.
36. Libby P. Molecular and cellular mechanisms of the thrombotic complications of atherosclerosis. J Lipid Res. 2009 (Suppl ); 50:S352-57.
37. Wick G. The heat is on: heat-shock proteins and atherosclerosis. Circulation. 2006; 114:870-72.
38. Durán MC, Martín-Ventura JL, Mohammed S, Barderas MG, Blanco-Colio LM, Mas S, Moral V, Ortega L, Tuñón J, Jensen ON, Vivanco F, Egido J. Atorvastatin modulates the profile of proteins released by human atherosclerotic plaques. Eur J Pharmacol. 2007; 562:119-29.
39. Martín-Ventura JL, Blanco-Colio LM, Gómez-Hernández A, Muñoz-García B, Vega M, Serrano J, Ortega L, Hernández G, Tuñón J, Egido J. Intensive treatment with atorvastatin reduces inflammation in mononuclear cells and human atherosclerotic lesions in one month. Stroke. 2005; 36:1796-800.
40. Shin YO, Bae JS, Lee JB, Kim JK, Kim YJ, Kim C, Ahn JK, Bang IK, Lee BK, Othman T, Min YK, Yang HM. Effect of cardiac rehabilitation and statin treatment on anti-HSP antibody titers in patients with coronary artery disease after percutaneous coronary intervention. Int Heart J. 2006; 47:671-82.
41. Steg PG, James SK, Atar D, Badano LP, Blömstrom-Lundqvist C, Borger MA, Di Mario C, Dickstein K, Ducrocq G, Fernandez-Aviles F, Gershlick AH, Giannuzzi P, Halvorsen S, et al, and Task Force on the management of ST-segment elevation acute myocardial infarction of the European Society of Cardiology (ESC). ESC Guidelines for the management of acute myocardial infarction in patients presenting with ST-segment elevation. Eur Heart J. 2012; 33:2569-619.
42. Janik S, Schiefer AI, Bekos C, Hacker P, Haider T, Moser J, Klepetko W, Müllauer L, Ankersmit HJ, Moser B. HSP27 and 70 expression in thymic epithelial tumors and benign thymic alterations: diagnostic, prognostic and physiologic implications. Sci Rep. 2016; 6:24267.
43. Göbel Y, Schaffer C, Koletzko B. Simultaneous determination of low plasma concentrations of retinol and tocopherols in preterm infants by a high-performance liquid chromatographic micromethod. J Chromatogr B Biomed Sci Appl. 1997; 688:57-62.
44. Tanboga IH, Topcu S, Aksakal E, Kalkan K, Sevimli S, Acikel M. Determinants of angiographic thrombus burden in patients with ST-segment elevation myocardial infarction. Clin Appl Thromb Hemost. 2014; 20:716-22.
45. Crea F, Gaspardone A, Tomai F, Shoulders C, De Fazio A, Versaci F, Iamele M, Roncaglioni C, Gioffré M, Maseri A, Gioffré PA. Risk factors in schoolchildren associated with a family history of unheralded myocardial infarction or uncomplicated stable angina in male relatives. J Am Coll Cardiol. 1994; 23:1472-78.