Enterovirus D68–Associated acute flaccid myelitis in immunocompromised woman, Italy

Emerging Infectious Diseases

Volumn 23, Issue 10, 2017, Pages 1690-1693

  Giombini, Emanuela ^a   Rueca, Martina ^a   Barberi, Walter ^b   Iori, Anna Paola ^b   Inghilleri, Maurizio ^b   Castilletti, Concetta ^a   Scognamiglio, Paola ^a,c   Vairo, Francesco ^a,c   Ippolito, Giuseppe ^a   Capobianchi, Maria Rosaria ^a   Valli, Maria Beatrice ^a  

^a NATIONAL INSTITUTE FOR INFECTIOUS DISEASES L SPALLANZANI   (Italy)

^b SAPIENZA UNIVERSITY OF ROME   (Italy)

^c Lazio Regional Service for the Surveillance of Infectious Disease (SeReSMI)   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ACICLOVIR; CIPROFLOXACIN; GLUCOSE; SULFAMETHOXAZOLE; TRIMETHOPRIM; IMMUNOSUPPRESSIVE AGENT;

ADENOVIRIDAE; ADULT; ARTICLE; ASEPTIC MENINGITIS; CEREBROSPINAL FLUID ANALYSIS; CYTOMEGALOVIRUS; DISEASE ASSOCIATION; ELECTROMYOGRAM; ENTEROVIRUS; ENTEROVIRUS D68; EPSTEIN BARR VIRUS; FEMALE; FLAVIVIRUS; GENE SEQUENCE; HEMATOPOIETIC STEM CELL; HERPES SIMPLEX VIRUS 2; HUMAN; IMMUNOCOMPROMISED PATIENT; ITALY; LYMPHOCYTE COUNT; MIDDLE AGED; MUSCLE WEAKNESS; MYELITIS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEOTIDE SEQUENCE; PLEOCYTOSIS; POLIOMYELITIS VIRUS; QUADRIPLEGIA; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; VARICELLA ZOSTER VIRUS; ACUTE DISEASE; ALLOTRANSPLANTATION; CASE REPORT; CLASSIFICATION; DIFFUSE LARGE B CELL LYMPHOMA; ENTEROVIRUS D; ENTEROVIRUS INFECTION; FATALITY; GENETICS; GENOTYPE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; IMMUNOLOGY; ISOLATION AND PURIFICATION; NONHODGKIN LYMPHOMA; PATHOGENICITY; PATHOLOGY; PHYLOGENY; VIROLOGY;

ACUTE DISEASE; ENTEROVIRUS D, HUMAN; ENTEROVIRUS INFECTIONS; FATAL OUTCOME; FEMALE; GENOTYPE; HEMATOPOIETIC STEM CELL TRANSPLANTATION; HUMANS; IMMUNOCOMPROMISED HOST; IMMUNOSUPPRESSIVE AGENTS; ITALY; LYMPHOMA, LARGE B-CELL, DIFFUSE; LYMPHOMA, NON-HODGKIN; MIDDLE AGED; MYELITIS; PHYLOGENY; TRANSPLANTATION, HOMOLOGOUS;

EID: 85029753137     PISSN: 10806040     EISSN: 10806059     Source Type: Journal    
DOI: 10.3201/eid2310.170792     Document Type: Article

References (15)

1. Holm-Hansen CC, Midgley SE, Fischer TK. Global emergence of enterovirus D68: a systematic review. Lancet Infect Dis. 2016;16:e64–75. http://dx.doi.org/10.1016/S1473-3099(15)00543-5
2. Oberste MS, Maher K, Schnurr D, Flemister MR, Lovchik JC, Peters H, et al. Enterovirus 68 is associated with respiratory illness and shares biological features with both the enteroviruses and the rhinoviruses. J Gen Virol. 2004;85:2577–84. http://dx.doi.org/10.1099/vir.0.79925-0
3. Tokarz R, Firth C, Madhi SA, Howie SR, Wu W, Sall AA, et al. Worldwide emergence of multiple clades of enterovirus 68. J Gen Virol. 2012;93:1952–8. http://dx.doi.org/10.1099/vir.0.043935-0
4. Knoester M, Schölvinck EH, Poelman R, Smit S, Vermont CL, Niesters HG, et al. Upsurge of enterovirus D68, the Netherlands, 2016. Emerg Infect Dis. 2017;23:140–3. http://dx.doi.org/10.3201/eid2301.161313
5. Aliabadi N, Messacar K, Pastula DM, Robinson CC, Leshem E, Sejvar JJ, et al. Enterovirus D68 infection in children with acute flaccid myelitis, Colorado, USA, 2014. Emerg Infect Dis. 2016;22:1387–94. http://dx.doi.org/10.3201/eid2208.151949
6. Kreuter JD, Barnes A, McCarthy JE, Schwartzman JD, Oberste MS, Rhodes CH, et al. A fatal central nervous system enterovirus 68 infection. Arch Pathol Lab Med. 2011;135:793–6. http://doi.org/10.1043/2010-0174-CR.1
7. Esposito S, Lunghi G, Zampiero A, Tagliabue C, Orlandi A, Torresani E, et al. Enterovirus-D68 in the cerebrospinal fluid of two children with aseptic meningitis. Pediatr Infect Dis J. 2016;35:589– 91. http://dx.doi.org/10.1097/INF.0000000000001085
8. Division of Viral Diseases, National Centers for Immunization and Respiratory Diseases, CDC; Division of Vector-Borne Diseases, Division of High-Consequence Pathogens and Pathology, National Center for Emerging and Zoonotic Infectious Diseases, CDC; Children’s Hospital Colorado; Council of State and Territorial Epidemiologists. Notes from the field: acute flaccid myelitis among persons aged ≤21 years—United States, August 1–November 13, 2014. MMWR Morb Mortal Wkly Rep. 2015;63:1243–4.
9. Oberste MS, Pallansch MA. Enterovirus molecular detection and typing. Rev Med Microbiol. 2005;16:163–71. http://dx.doi.org/10.1097/01.revmedmi.0000184741.90926.35
10. Kroneman A, Vennema H, Deforche K, v d Avoort H, Peñaranda S, Oberste MS, et al. An automated genotyping tool for enteroviruses and noroviruses. J Clin Virol. 2011;51:121–5. 10.1016/j.jcv.2011.03.006 http://dx.doi.org/10.1016/j.jcv.2011.03.006
11. Greninger AL, Naccache SN, Messacar K, Clayton A, Yu G, Somasekar S, et al. A novel outbreak enterovirus D68 strain associated with acute flaccid myelitis cases in the USA (2012–14): a retrospective cohort study. Lancet Infect Dis. 2015;15:671–82. http://dx.doi.org/10.1016/S1473-3099(15)70093-9
12. Waghmare A, Pergam SA, Jerome KR, Englund JA, Boeckh M, Kuypers J. Clinical disease due to enterovirus D68 in adult hematologic malignancy patients and hematopoietic cell transplant recipients. Blood. 2015;125:1724–9. http://dx.doi.org/10.1182/blood-2014-12-616516
13. Hixon AM, Yu G, Leser JS, Yagi S, Clarke P, Chiu CY, et al. A mouse model of paralytic myelitis caused by enterovirus D68. PLoS Pathog. 2017;13:e1006199. http://dx.doi.org/10.1371/journal.ppat.1006199
14. Pariani E, Pellegrinelli L, Merlone AD, Piralla A, Baldanti F, Binda S. Letter to the editor: need for a European network for enterovirus D68 surveillance after detections of EV-D68 of the new B3 lineage in Sweden and Italy, 2016. Euro Surveill. 2017;22:30440. http://dx.doi.org/10.2807/1560-7917. ES.2017.22.2.30440
15. Midgley CM, Jackson MA, Selvarangan R, Turabelidze G, Obringer E, Johnson D, et al. Severe respiratory illness associated with enterovirus D68—Missouri and Illinois, 2014. MMWR Morb Mortal Wkly Rep. 2014;63:798–9.