Human papillomavirus in oropharyngeal squamous cell carcinoma in South-Eastern Norway: prevalence, genotype, and survival

European Archives of Oto-Rhino-Laryngology

Volumn 274, Issue 11, 2017, Pages 4003-4010

  Fossum, Guro Haugen ^a   Lie, Agnes Kathrine ^a,b   Jebsen, Peter ^a   Sandlie, Lars Erik ^a,c   Mork, Jon ^a  

^a OSLO UNIVERSITY HOSPITAL   (Norway)

^b stfold Hospital Kalnes   (Norway)

^c Roche Norway   (Norway)

Author keywords

Genotypes; Human papillomavirus (HPV); Oropharyngeal cancer; Prevalence; Survival

Indexed keywords

PROTEIN P16; VIRUS DNA;

ADULT; AGED; ALGORITHM; ARTICLE; CANCER SURVIVAL; CASE STUDY; COHORT ANALYSIS; DISEASE ASSOCIATION; EUROPE; FEMALE; GENOTYPE; HIGH RISK PATIENT; HUMAN; HUMAN PAPILLOMAVIRUS TYPE 16; HUMAN PAPILLOMAVIRUS TYPE 18; HUMAN PAPILLOMAVIRUS TYPE 31; HUMAN PAPILLOMAVIRUS TYPE 33; HUMAN PAPILLOMAVIRUS TYPE 35; HUMAN PAPILLOMAVIRUS TYPE 56; HUMAN PAPILLOMAVIRUS TYPE 59; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; MAJOR CLINICAL STUDY; MALE; NORTH AMERICA; NORWAY; NORWEGIAN (PEOPLE); OROPHARYNX SQUAMOUS CELL CARCINOMA; OVERALL SURVIVAL; POLYMERASE CHAIN REACTION; POPULATION RESEARCH; PREVALENCE; PRIORITY JOURNAL; RETROSPECTIVE STUDY; VIRUS GENOME; WART VIRUS; GENETICS; ISOLATION AND PURIFICATION; MIDDLE AGED; MORTALITY; OROPHARYNX TUMOR; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTION; PROPORTIONAL HAZARDS MODEL; SQUAMOUS CELL CARCINOMA; SURVIVAL ANALYSIS; VERY ELDERLY; VIROLOGY;

ADULT; AGED; AGED, 80 AND OVER; CARCINOMA, SQUAMOUS CELL; COHORT STUDIES; FEMALE; GENOTYPE; HUMAN PAPILLOMAVIRUS 16; HUMANS; IMMUNOHISTOCHEMISTRY; MALE; MIDDLE AGED; NORWAY; OROPHARYNGEAL NEOPLASMS; PAPILLOMAVIRIDAE; PAPILLOMAVIRUS INFECTIONS; POLYMERASE CHAIN REACTION; PREVALENCE; PROPORTIONAL HAZARDS MODELS; SURVIVAL ANALYSIS;

EID: 85029593806     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-017-4748-8     Document Type: Article

References (25)

1. Ang KK, Harris J, Wheeler R, Weber R, Rosenthal DI, Nguyen-Tan PF, Westra WH, Chung CH, Jordan RC, Lu C, Kim H, Axelrod R, Silverman CC, Redmond KP, Gillison ML (2010) Human papillomavirus and survival of patients with oropharyngeal cancer. N Engl J Med 363(1):24–35. doi:10.1056/NEJMoa0912217
2. Fakhry C, Psyrri A, Chaturvedhi A (2014) HPV and head and neck cancers: state-of-the-science. Oral Oncol 50(5):353–355. doi:10.1016/j.oraloncology.2014.03.010
3. Fakhry C, Westra WH, Li S, Cmelak A, Ridge JA, Pinto H, Forastiere A, Gillison ML (2008) Improved survival of patients with human papillomavirus-positive head and neck squamous cell carcinoma in a prospective clinical trial. J Natl Cancer Inst 100(4):261–269. doi:10.1093/jnci/djn011
4. Chaturvedi AK, Anderson WF, Lortet-Tieulent J, Curado MP, Ferlay J, Franceschi S, Rosenberg PS, Bray F, Gillison ML (2013) Worldwide trends in incidence rates for oral cavity and oropharyngeal cancers. J Clin Oncol Off J Am Soc Clin Oncol 31(36):4550–4559. doi:10.1200/JCO.2013.50.3870
5. Chaturvedi AK, Engels EA, Pfeiffer RM, Hernandez BY, Xiao W, Kim E, Jiang B, Goodman MT, Sibug-Saber M, Cozen W, Liu L, Lynch CF, Wentzensen N, Jordan RC, Altekruse S, Anderson WF, Rosenberg PS, Gillison ML (2011) Human papillomavirus and rising oropharyngeal cancer incidence in the United States. J Clin Oncol Off J Am Soc Clin Oncol 29(32):4294–4301. doi:10.1200/JCO.2011.36.4596
6. Nasman A, Attner P, Hammarstedt L, Du J, Eriksson M, Giraud G, Ahrlund-Richter S, Marklund L, Romanitan M, Lindquist D, Ramqvist T, Lindholm J, Sparen P, Ye W, Dahlstrand H, Munck-Wikland E, Dalianis T (2009) Incidence of human papillomavirus (HPV) positive tonsillar carcinoma in Stockholm, Sweden: an epidemic of viral-induced carcinoma? Int J Cancer (Journal international du cancer) 125(2):362–366. doi:10.1002/ijc.24339
7. Simard EP, Torre LA, Jemal A (2014) International trends in head and neck cancer incidence rates: differences by country, sex and anatomic site. Oral Oncol 50(5):387–403. doi:10.1016/j.oraloncology.2014.01.016
8. Mehanna H, Beech T, Nicholson T, El-Hariry I, McConkey C, Paleri V, Roberts S (2013) Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer—systematic review and meta-analysis of trends by time and region. Head Neck 35(5):747–755. doi:10.1002/hed.22015
9. Rodrigo JP, Heideman DA, Garcia-Pedrero JM, Fresno MF, Brakenhoff RH, Diaz Molina JP, Snijders PJ, Hermsen MA (2014) Time trends in the prevalence of HPV in oropharyngeal squamous cell carcinomas in northern Spain (1990–2009). Int J Cancer (Journal international du cancer) 134(2):487–492. doi:10.1002/ijc.28355
10. Nasman A, Nordfors C, Holzhauser S, Vlastos A, Tertipis N, Hammar U, Hammarstedt-Nordenvall L, Marklund L, Munck-Wikland E, Ramqvist T, Bottai M, Dalianis T (2015) Incidence of human papillomavirus positive tonsillar and base of tongue carcinoma: a stabilisation of an epidemic of viral induced carcinoma? Eur J Cancer Oxford England: 1950 51(1):55–61. doi:10.1016/j.ejca.2014.10.016
11. Mork J, Moller B, Dahl T, Bray F (2010) Time trends in pharyngeal cancer incidence in Norway 1981–2005: a subsite analysis based on a reabstraction and recoding of registered cases. Cancer Causes Control CCC 21(9):1397–1405. doi:10.1007/s10552-010-9567-9
12. Goodman MT, Saraiya M, Thompson TD, Steinau M, Hernandez BY, Lynch CF, Lyu CW, Wilkinson EJ, Tucker T, Copeland G, Peters ES, Altekruse S, Unger ER (2015) Human papillomavirus genotype and oropharynx cancer survival in the United States of America. Eur J Cancer (Oxford, England: 1990) 51(18):2759–2767. doi:10.1016/j.ejca.2015.09.005
13. Mazul AL, Rodriguez-Ormaza N, Taylor JM, Desai DD, Brennan P, Anantharaman D, Gheit T, Tommasino M, Abedi-Ardekani B, Olshan AF, Zevallos JP (2016) Prognostic significance of non-HPV16 genotypes in oropharyngeal squamous cell carcinoma. Oral Oncol 61:98–103. doi:10.1016/j.oraloncology.2016.08.019
14. Varier I, Keeley BR, Krupar R, Patsias A, Dong J, Gupta N, Parasher AK, Genden EM, Miles BA, Teng M, Bakst RL, Gupta V, Misiukiewicz KJ, Chiao EY, Scheurer ME, Laban S, Zhang D, Ye F, Cui M, Demicco EG, Posner MR, Sikora AG (2016) Clinical characteristics and outcomes of oropharyngeal carcinoma related to high-risk non-human papillomavirus16 viral subtypes. Head Neck 38(9):1330–1337. doi:10.1002/hed.24442
15. Lindh M, Gorander S, Andersson E, Horal P, Mattsby-Balzer I, Ryd W (2007) Real-time Taqman PCR targeting 14 human papilloma virus types. J Clin Virol Off Publ Pan Am Soc Clin Virol 40(4):321–324. doi:10.1016/j.jcv.2007.09.009
16. Mork J, Lie AK, Glattre E, Hallmans G, Jellum E, Koskela P, Moller B, Pukkala E, Schiller JT, Youngman L, Lehtinen M, Dillner J (2001) Human papillomavirus infection as a risk factor for squamous-cell carcinoma of the head and neck. N Engl J Med 344(15):1125–1131. doi:10.1056/NEJM200104123441503
17. Hannisdal K, Schjolberg A, De Angelis PM, Boysen M, Clausen OP (2010) Human papillomavirus (HPV)-positive tonsillar carcinomas are frequent and have a favourable prognosis in males in Norway. Acta Otolaryngol 130(2):293–299. doi:10.3109/00016480903071377
18. Garnaes E, Kiss K, Andersen L, Therkildsen MH, Franzmann MB, Filtenborg-Barnkob B, Hoegdall E, Krenk L, Josiassen M, Lajer CB, Specht L, Frederiksen K, Friis-Hansen L, Nielsen FC, Kjaer SK, Norrild B, von Buchwald C (2015) A high and increasing HPV prevalence in tonsillar cancers in Eastern Denmark, 2000–2010: the largest registry-based study to date. Int J Cancer (Journal international du cancer) 136(9):2196–2203. doi:10.1002/ijc.29254
19. Ndiaye C, Mena M, Alemany L, Arbyn M, Castellsague X, Laporte L, Bosch FX, de Sanjose S, Trottier H (2014) HPV DNA, E6/E7 mRNA, and p16INK4a detection in head and neck cancers: a systematic review and meta-analysis. Lancet Oncol 15(12):1319–1331. doi:10.1016/S1470-2045(14)70471-1
20. IARC (2012) Biological agents. IARC Monographs on the Evaluation of Carcinogenic Risks to Humans, vol 100B. IARC, Lyon, pp 275–276
21. Hill AB (1965) The environment and disease: association or causation? Proc R Soc Med 58:295–300
22. Gillison ML, Koch WM, Capone RB, Spafford M, Westra WH, Wu L, Zahurak ML, Daniel RW, Viglione M, Symer DE, Shah KV, Sidransky D (2000) Evidence for a causal association between human papillomavirus and a subset of head and neck cancers. J Natl Cancer Inst 92(9):709–720
23. O’Rorke MA, Ellison MV, Murray LJ, Moran M, James J, Anderson LA (2012) Human papillomavirus related head and neck cancer survival: a systematic review and meta-analysis. Oral Oncol 48(12):1191–1201. doi:10.1016/j.oraloncology.2012.06.019
24. Mirghani H, Amen F, Blanchard P, Moreau F, Guigay J, Hartl DM, Lacau St Guily J (2015) Treatment de-escalation in HPV-positive oropharyngeal carcinoma: ongoing trials, critical issues and perspectives. Int J Cancer (Journal international du cancer) 136(7):1494–1503. doi:10.1002/ijc.28847
25. Kelly JR, Husain ZA, Burtness B (2016) Treatment de-intensification strategies for head and neck cancer. Eur J Cancer (Oxford, England: 1990) 68:125–133. doi:10.1016/j.ejca.2016.09.006