Prevalence of fosfomycin resistance and plasmid-mediated fosfomycin-modifying enzymes among carbapenem-resistant enterobacteriaceae in Zhejiang, China

Journal of Medical Microbiology

Volumn 66, Issue 9, 2017, Pages 1332-1334

  Huang, Lin ^a   Hu, Yan Yan ^a   Zhang, Rong ^a  

^a THE SECOND AFFILIATED HOSPITAL OF ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

Author keywords

Carbapenem resistant enterobacteriaceae; Fosfomycin; Fosfomycin modifying enzyme; Plasmid

Indexed keywords

AMPICILLIN; CEFAZOLIN; CEFUROXIME; ENZYME; FOSA ENZYME; FOSA2 ENZYME; FOSA3 ENZYME; FOSA5 ENZYME; FOSFOMYCIN; UNCLASSIFIED DRUG; CARBAPENEM DERIVATIVE; ESCHERICHIA COLI PROTEIN; FOSA(3) PROTEIN, E COLI; FOSA5 PROTEIN, E COLI;

ANTIBIOTIC SENSITIVITY; ARTICLE; CARBAPENEM RESISTANT ENTEROBACTERIACEAE; CHINA; CITROBACTER FREUNDII; DRUG RESISTANCE; ENTEROBACTER CLOACAE; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE MUTATION; KLEBSIELLA PNEUMONIAE; MINIMUM INHIBITORY CONCENTRATION; MORGANELLA MORGANII; MULTICENTER STUDY; NONHUMAN; PLASMID; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; SERRATIA MARCESCENS; COMPARATIVE STUDY; DRUG EFFECTS; ENTEROBACTERIACEAE INFECTIONS; GENETICS; HORIZONTAL GENE TRANSFER; HUMAN; ISOLATION AND PURIFICATION; MICROBIAL SENSITIVITY TEST; MICROBIOLOGY; MULTIDRUG RESISTANCE;

CARBAPENEMS; CHINA; DRUG RESISTANCE, MULTIPLE, BACTERIAL; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE INFECTIONS; ESCHERICHIA COLI; ESCHERICHIA COLI PROTEINS; FOSFOMYCIN; GENE TRANSFER, HORIZONTAL; HUMANS; KLEBSIELLA PNEUMONIAE; MICROBIAL SENSITIVITY TESTS; PLASMIDS;

EID: 85029586259     PISSN: 00222615     EISSN: None     Source Type: Journal    
DOI: 10.1099/jmm.0.000578     Document Type: Article

References (24)

1. Gupta N, Limbago BM, Patel JB, Kallen AJ. Carbapenem-resistant Enterobacteriaceae: epidemiology and prevention. Clin Infect Dis 2011;53:60-67.
2. Schultsz C, Geerlings S. Plasmid-mediated resistance in Enterobacteriaceae:changing landscape and implications for therapy. Drugs 2012;72:1-16.
3. Kastoris AC, Rafailidis PI, Vouloumanou EK, Gkegkes ID, Falagas ME. Synergy of fosfomycin with other antibiotics for Gram-positive and Gram-negative bacteria. Eur J Clin Pharmacol 2010;66:359-368.
4. Suárez JE, Mendoza MC. Plasmid-encoded fosfomycin resistance. Antimicrob Agents Chemother 1991;35:791-795.
5. Falagas ME, Kastoris AC, Kapaskelis AM, Karageorgopoulos DE. Fosfomycin for the treatment of multidrug-resistant, including extended-spectrum b-lactamase producing, Enterobacteriaceae infections: a systematic review. Lancet Infect Dis 2010;10:43-50.
6. Arca P, Rico M, Braña AF, Villar CJ, Hardisson C et al. Formation of an adduct between fosfomycin and glutathione: a new mechanism of antibiotic resistance in bacteria. Antimicrob Agents Chemother 1988;32:1552-1556.
7. Xu H, Miao V, Kwong W, Xia R, Davies J. Identification of a novel fosfomycin resistance gene (fosA2) in Enterobacter cloacae from the Salmon River, Canada. Lett Appl Microbiol 2011;52:427-429.
8. Wachino J, Yamane K, Suzuki S, Kimura K, Arakawa Y. Prevalence of fosfomycin resistance among CTX-M-producing Escherichia coli clinical isolates in Japan and identification of novel plasmid-mediated fosfomycin-modifying enzymes. Antimicrob Agents Chemother 2010;54:3061-3064.
9. Nakamura G, Wachino J, Sato N, Kimura K, Yamada K et al. Practical agar-based disk potentiation test for detection of fosfomycin- nonsusceptible Escherichia coli clinical isolates producing glutathione S-transferases. J Clin Microbiol 2014;52:3175-3179.
10. Wareham D, Sab Z, Phee LM, Mhf AM et al. Co-carriage of plasmid- mediated fosfomycin resistance determinants (fos) by carbapenem resistant Enterobacteriaceae in the United Kingdom. Asm Microbe 2016.
11. Patel JB, Cockerill Iii FR, Alder J. Performance Standards for Antimicrobial Susceptibility Testing; Twenty-Fourth Informational Supplement. Clinical and Laboratory Standards Institute antimicrobial susceptibility testing M100-S24, vol. 34; 2014. pp. 1-230.
12. Hou J, Huang X, Deng Y, He L, Yang T et al. Dissemination of the fosfomycin resistance gene fosA3 with CTX-M b-lactamase genes and rmtB carried on IncFII plasmids among Escherichia coli isolates from pets in China. Antimicrob Agents Chemother 2012;56:2135-2138.
13. Ma Y, Xu X, Guo Q, Wang P, Wang W et al. Characterization of fosA5, a new plasmid-mediated fosfomycin resistance gene in Escherichia coli. Lett Appl Microbiol 2015;60:259-264.
14. García P, Arca P, Toyos JR, Suárez JE. Detection of fosfomycin resistance by the polymerase chain reaction and Western blotting. J Antimicrob Chemother 1994;34:955-963.
15. Zilhao R, Courvalin P. Nucleotide sequence of the fosB gene conferring fosfomycin resistance in Staphylococcus epidermidis. FEMS Microbiol Lett 1990;56:267.
16. Zilberberg MD, Shorr AF. Prevalence of multidrug-resistant Pseudomonas aeruginosa and carbapenem-resistant Enterobacteriaceae among specimens from hospitalized patients with pneumonia and bloodstream infections in the United States from 2000 to 2009. J Hosp Med 2013;8:559-563.
17. Kazi M, Drego L, Nikam C, Ajbani K, Soman R et al. Molecular characterization of carbapenem-resistant Enterobacteriaceae at a tertiary care laboratory in Mumbai. Eur J Clin Microbiol Infect Dis 2015;34:467-472.
18. Okoche D, Asiimwe BB, Katabazi FA, Kato L, Najjuka CF et al. Prevalence and characterization of carbapenem-resistant Enterobacteriaceae isolated from Mulago National Referral Hospital, Uganda. PLoS One 2015;10:e0135745.
19. Drew RJ, Turton JF, Hill RL, Livermore DM, Woodford N et al. Emergence of carbapenem-resistant Enterobacteriaceae in a UK paediatric hospital. J Hosp Infect 2013;84:300-304.
20. Garau M, Latorre A, Alonso-Sanz M. Fosfomycin: an underrated antibiotic for urinary tract infections due to Escherichia coli. Enferm Infecc Microbiol Clin 2001;19:462-466.
21. Seo MR, Kim SJ, Kim Y, Kim J, Choi TY et al. Susceptibility of Escherichia coli from community-acquired urinary tract infection to fosfomycin, nitrofurantoin, and temocillin in Korea. J Korean Med Sci 2014;29:1178-1181.
22. Nabeth P, Perrier-Gros-Claude JD, Juergens-Behr A, Dromigny JA. In vitro susceptibility of quinolone-resistant Enterobacteriaceae uropathogens to fosfomycin trometamol, in Dakar, Senegal. Scand J Infect Dis 2005;37:497-499.
23. Al-Zarouni M, Senok A, Al-Zarooni N, Al-Nassay F, Panigrahi D. Extended-spectrum b-lactamase-producing Enterobacteriaceae:in vitro susceptibility to fosfomycin, nitrofurantoin and tigecycline. Med Princ Pract 2012;21:543-547.
24. Takahata S, Ida T, Hiraishi T, Sakakibara S, Maebashi K et al. Molecular mechanisms of fosfomycin resistance in clinical isolates of Escherichia coli. Int J Antimicrob Agents 2010;35:333-337.