Selenium increases hepatic DNA methylation and modulates one-carbon metabolism in the liver of mice

Journal of Nutritional Biochemistry

Volumn 48, Issue , 2017, Pages 112-119

  Speckmann, Bodo ^a   Schulz, Sarah ^a   Hiller, Franziska ^a   Hesse, Deike ^a,b   Schumacher, Fabian ^c,d   Kleuser, Burkhard ^c,e   Geisel, Jürgen ^f   Obeid, Rima ^f,g   Grune, Tilman ^a,b,h   Kipp, Anna P ⁱ  

^a GERMAN INSTITUTE OF HUMAN NUTRITION   (Germany)

^b GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^c UNIVERSITY OF POTSDAM   (Germany)

^d UNIVERSITY OF DUISBURG ESSEN   (Germany)

^e NutriAct Competence Cluster for Nutritional Sciences Berlin Potsdam   (Germany)

^f SAARLAND UNIVERSITY   (Germany)

^g AARHUS UNIVERSITY   (Denmark)

^h DZHK GERMAN CENTRE FOR CARDIOVASCULAR RESEARCH   (Germany)

ⁱ FRIEDRICH SCHILLER UNIVERSITY JENA   (Germany)

Author keywords

DNA methylation; Lipogenesis; Liver; Selenium; Srebf1

Indexed keywords

DNA METHYLTRANSFERASE 1; GLUTATHIONE PEROXIDASE; GLYCINE HYDROXYMETHYLTRANSFERASE; HEPATOCYTE NUCLEAR FACTOR 1BETA; PEROXISOME PROLIFERATOR ACTIVATED RECEPTOR ALPHA; S ADENOSYLHOMOCYSTEINE; SELENIUM; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIACYLGLYCEROL; CARBON; S ADENOSYLMETHIONINE; SHMT1 PROTEIN, MOUSE; SREBF1 PROTEIN, RAT;

AMPLICON; ANIMAL EXPERIMENT; ARTICLE; CARBON METABOLISM; COMPARATIVE STUDY; CONTROLLED STUDY; DNA METHYLATION; ENZYME ACTIVITY; GENE EXPRESSION; GLUCOSE METABOLISM; LIMIT OF QUANTITATION; LIPID METABOLISM; LIPOGENESIS; LIVER; LIVER CELL; MOUSE; NONHUMAN; REAL TIME POLYMERASE CHAIN REACTION; TRIACYLGLYCEROL BLOOD LEVEL; UPREGULATION; ANIMAL; BLOOD; C57BL MOUSE; DRUG EFFECTS; GENETICS; GLYCOLYSIS; METABOLISM;

ANIMALS; CARBON; DNA METHYLATION; GLYCINE HYDROXYMETHYLTRANSFERASE; GLYCOLYSIS; LIPID METABOLISM; LIVER; MICE, INBRED C57BL; S-ADENOSYLHOMOCYSTEINE; S-ADENOSYLMETHIONINE; SELENIUM; STEROL REGULATORY ELEMENT BINDING PROTEIN 1; TRIGLYCERIDES; UP-REGULATION;

EID: 85029170868     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2017.07.002     Document Type: Article

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