Corrigendum: A randomized synbiotic trial to prevent sepsis among infants in rural India (Nature (2017) 548 (407-412) DOI: 10.1038/nature23480);A randomized synbiotic trial to prevent sepsis among infants in rural India

Nature

Volumn 548, Issue 7668, 2017, Pages 407-412

  Panigrahi, Pinaki ^a   Parida, Sailajanandan ^b   Nanda, Nimai C ^c   Satpathy, Radhanath ^d   Pradhan, Lingaraj ^e   Chandel, DInesh S ^a   Baccaglini, Lorena ^a   Mohapatra, Arjit ^d   Mohapatra, Subhranshu S ^d   Misra, Pravas R ^d   Chaudhry, Rama ^f   Chen, Hegang H ^g   Johnson, Judith A ^h   Morris, J Glenn ^h   Paneth, Nigel ⁱ   Gewolb, Ira H ⁱ  

^a UNIVERSITY OF NEBRASKA MEDICAL CENTER   (United States)

^b SCB MEDICAL COLLEGE   (India)

^c ISPAT GENERAL HOSPITAL   (India)

^d Asian Institute of Public Health   (India)

^e Capital Hospital   (India)

^f ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^g UNIVERSITY OF MARYLAND SCHOOL OF MEDICINE   (United States)

^h UNIVERSITY OF FLORIDA   (United States)

ⁱ MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

FRUCTOSE OLIGOSACCHARIDE; PLACEBO; SYNBIOTIC AGENT; OLIGOSACCHARIDE;

CHILD HEALTH; DEVELOPING WORLD; DISEASE TREATMENT; INFECTIOUS DISEASE; MORBIDITY; MORTALITY; RESPIRATORY DISEASE; RURAL AREA;

ABSCESS; ARTICLE; CHICKENPOX; CLINICAL OUTCOME; CONGENITAL HEART DISEASE; CONJUNCTIVITIS; CONTROLLED STUDY; DIARRHEA; DOUBLE BLIND PROCEDURE; GRAM NEGATIVE SEPSIS; GRAM POSITIVE INFECTION; HUMAN; HYPOTHERMIA; INDIA; LACTOBACILLUS PLANTARUM; LOWER RESPIRATORY TRACT INFECTION; MAJOR CLINICAL STUDY; MORBIDITY; NECROTIZING FASCIITIS; NEWBORN; NEWBORN DEATH; NEWBORN SEPSIS; OMPHALITIS; OTITIS MEDIA; PNEUMONIA; PRIORITY JOURNAL; PUSTULE; RANDOMIZED CONTROLLED TRIAL; RURAL POPULATION; SEPSIS; SEPTICEMIA; THERAPY EFFECT; THRUSH; ADULT; DIET THERAPY; FEMALE; FOLLOW UP; INFANT; MICROBIOLOGY; MORTALITY; YOUNG ADULT;

INDIA;

LACTOBACILLUS PLANTARUM;

ADULT; DOUBLE-BLIND METHOD; FEMALE; FOLLOW-UP STUDIES; HUMANS; INDIA; INFANT; INFANT, NEWBORN; LACTOBACILLUS PLANTARUM; OLIGOSACCHARIDES; SEPSIS; SYNBIOTICS; YOUNG ADULT;

EID: 85028348393     PISSN: 00280836     EISSN: 14764687     Source Type: Journal    
DOI: 10.1038/nature25006     Document Type: Erratum

References (51)

1. Thaver, D. & Zaidi, A. K. Burden of neonatal infections in developing countries: a review of evidence from community-based studies. Pediatr. Infect. Dis. J. 28 (suppl. 1), S3-S9 (2009).
2. Liu, L. et al. Global, regional, and national causes of child mortality in 2000-13, with projections to inform post-2015 priorities: an updated systematic analysis. Lancet 385, 430-440 (2015).
3. United Nations Inter-agency Group for Child Mortality Estimation. Levels and Trends in Child Mortality; https://www.unicef.org/media/files/Levels-and-Trends-in-Child-Mortality-2014.pdf (UNICEF, WHO, The World Bank, UNDP, 2014).
4. Seale, A. C. et al. Estimates of possible severe bacterial infection in neonates in sub-Saharan Africa, south Asia, and Latin America for 2012: a systematic review and meta-analysis. Lancet Infect. Dis. 14, 731-741 (2014).
5. Blencowe, H. et al. Estimates of neonatal morbidities and disabilities at regional and global levels for 2010: introduction, methods overview, and relevant findings from the Global Burden of Disease study. Pediatr. Res. 74 (suppl. 1), 4-16 (2013).
6. Lawn, J. E. et al. Every Newborn: progress, priorities, and potential beyond survival. Lancet 384, 189-205 (2014).
7. Oza, S., Lawn, J. E., Hogan, D. R., Mathers, C. & Cousens, S. N. Neonatal cause-of-death estimates for the early and late neonatal periods for 194 countries: 2000-2013. Bull. World Health Organ. 93, 19-28 (2015).
8. Boghossian, N. S. et al. Late-onset sepsis in very low birth weight infants from singleton and multiple-gestation births. J. Pediatr. 162, 1120-1124.e1 (2013).
9. Marshall, J. C. Why have clinical trials in sepsis failed? Trends Mol. Med. 20, 195-203 (2014).
10. The INIS Collaborative Group. Treatment of neonatal sepsis with intravenous immune globulin. N. Engl. J. Med. 365, 1201-1211 (2011).
11. Mullany, L. C., Darmstadt, G. L. & Tielsch, J. M. Safety and impact of chlorhexidine antisepsis interventions for improving neonatal health in developing countries. Pediatr. Infect. Dis. J. 25, 665-675 (2006).
12. Gewolb, I. H., Schwalbe, R. S., Taciak, V. L., Harrison, T. S. & Panigrahi, P. Stool microflora in extremely low birthweight infants. Arch. Dis. Child. Fetal Neonatal Ed. 80, F167-F173 (1999).
13. AlFaleh, K. & Anabrees, J. Probiotics for prevention of necrotizing enterocolitis in preterm infants. Cochrane Database Syst. Rev. http://dx.doi.org/10.1002/14651858.CD005496.pub4 (2014).
14. Dilli, D. et al. Treatment outcomes of infants with cyanotic congenital heart disease treated with synbiotics. Pediatrics 132, e932-e938 (2013).
15. Dilli, D. et al. The ProPre-Save study: effects of probiotics and prebiotics alone or combined on necrotizing enterocolitis in very low birth weight infants. J. Pediatr. 166, 545-51.e1 (2015).
16. Nandhini, L. et al. Synbiotics for decreasing incidence of necrotizing enterocolitis among preterm neonates - a randomized controlled trial. J. Matern. Fetal Neonatal Med. 29, 821-825 (2016).
17. Jacobs, S. E. et al. Probiotic effects on late-onset sepsis in very preterm infants: a randomized controlled trial. Pediatrics 132, 1055-1062 (2013).
18. Costeloe, K. et al. Bifidobacterium breve BBG-001 in very preterm infants: a randomised controlled phase 3 trial. Lancet 387, 649-660 (2016).
19. Agarwal, R. et al. Effects of oral Lactobacillus GG on enteric microflora in low-birth-weight neonates. J. Pediatr. Gastroenterol. Nutr. 36, 397-402 (2003).
20. Panigrahi, P. et al. Long-term colonization of a Lactobacillus plantarum synbiotic preparation in the neonatal gut. J. Pediatr. Gastroenterol. Nutr. 47, 45-53 (2008).
21. National Health Mission. Health Statistics; http://www.nrhmorissa.gov.in/frmhealthstatistics.aspx (2011).
22. Sinha, A. et al. Role of probiotics VSL#3 in prevention of suspected sepsis in low birthweight infants in India: a randomised controlled trial. BMJ Open 5, e006564 (2015).
23. Waters, D. et al. Aetiology of community-acquired neonatal sepsis in low and middle income countries. J. Glob. Health 1, 154-170 (2011).
24. Panigrahi, P., Gupta, S., Gewolb, I. H. & Morris, J. G. Jr. Occurrence of necrotizing enterocolitis may be dependent on patterns of bacterial adherence and intestinal colonization: studies in Caco-2 tissue culture and weanling rabbit models. Pediatr. Res. 36, 115-121 (1994).
25. Panigrahi, P., Bamford, P., Horvath, K., Morris, J. G. Jr & Gewolb, I. H. Escherichia coli transcytosis in a Caco-2 cell model: implications in neonatal necrotizing enterocolitis. Pediatr. Res. 40, 415-421 (1996).
26. Khailova, L., Baird, C. H., Rush, A. A., McNamee, E. N. & Wischmeyer, P. E. Lactobacillus rhamnosus GG improves outcome in experimental pseudomonas aeruginosa pneumonia: potential role of regulatory T cells. Shock 40, 496-503 (2013).
27. Chu, H. & Mazmanian, S. K. Innate immune recognition of the microbiota promotes host-microbial symbiosis. Nat. Immunol. 14, 668-675 (2013).
28. Renz, H., Brandtzaeg, P. & Hornef, M. The impact of perinatal immune development on mucosal homeostasis and chronic inflammation. Nat. Rev. Immunol. 12, 9-23 (2011).
29. Arrieta, M. C., Stiemsma, L. T., Amenyogbe, N., Brown, E. M. & Finlay, B. The intestinal microbiome in early life: health and disease. Front. Immunol. 5, 427 (2014).
30. Deshmukh, H. S. et al. The microbiota regulates neutrophil homeostasis and host resistance to Escherichia coli K1 sepsis in neonatal mice. Nat. Med. 20, 524-530 (2014).
31. Kiso, M. et al. Protective efficacy of orally administered, heat-killed Lactobacillus pentosus b240 against influenza A virus. Sci. Rep. 3, 1563 (2013).
32. Tanaka, A. et al. Lactobacillus pentosus strain b240 suppresses pneumonia induced by Streptococcus pneumoniae in mice. Lett. Appl. Microbiol. 53, 35-43 (2011).
33. Moles, L. et al. Bacterial diversity in meconium of preterm neonates and evolution of their fecal microbiota during the first month of life. PLoS One 8, e66986 (2013).
34. Aagaard, K. et al. The placenta harbors a unique microbiome. Sci. Transl. Med. 6, 237ra65 (2014).
35. Arrieta, M. C. et al. Early infancy microbial and metabolic alterations affect risk of childhood asthma. Sci. Transl. Med. 7, 307ra152 (2015).
36. Khosravi, A. et al. Gut microbiota promote hematopoiesis to control bacterial infection. Cell Host Microbe 15, 374-381 (2014).
37. Hensey, O. J., Hart, C. A. & Cooke, R. W. Serious infection in a neonatal intensive care unit: a two-year survey. J. Hyg. (Lond.) 95, 289-297 (1985).
38. Spigelblatt, L., Saintonge, J., Chicoine, R. & Laverdière, M. Changing pattern of neonatal streptococcal septicemia. Pediatr. Infect. Dis. 4, 56-58 (1985).
39. West, P. W. et al. Speciation of presumptive viridans streptococci from early onset neonatal sepsis. J. Med. Microbiol. 47, 923-928 (1998).
40. Schrag, S. J. et al. Epidemiology of invasive early-onset neonatal sepsis, 2005 to 2014. Pediatrics 138, e20162013 (2016).
41. Jalilsood, T. et al. Characterization of pR18, a novel rolling-circle replication plasmid from Lactobacillus plantarum. Plasmid 73, 1-9 (2014).
42. Jacobsen, L. et al. Horizontal transfer of tet(M) and erm(B) resistance plasmids from food strains of Lactobacillus plantarum to Enterococcus faecalis JH2-2 in the gastrointestinal tract of gnotobiotic rats. FEMS Microbiol. Ecol. 59, 158-166 (2007).
43. Feld, L. et al. Selective pressure affects transfer and establishment of a Lactobacillus plantarum resistance plasmid in the gastrointestinal environment. J. Antimicrob. Chemother. 61, 845-852 (2008).
44. Toomey, N., Bolton, D. & Fanning, S. Characterisation and transferability of antibiotic resistance genes from lactic acid bacteria isolated from Irish pork and beef abattoirs. Res. Microbiol. 161, 127-135 (2010).
45. Bujalance, C., Jiménez-Valera, M., Moreno, E. & Ruiz-Bravo, A. A selective differential medium for Lactobacillus plantarum. J. Microbiol. Methods 66, 572-575 (2006).
46. Lai, E. M., Nathan, A. M., de Bruyne, J. A. & Chan, L. L. Should all children admitted with community acquired pneumonia have blood cultures taken? Indian J. Pediatr. 82, 439-444 (2015).
47. McCulloh, R. J. et al. Evaluating the use of blood cultures in the management of children hospitalized for community-acquired pneumonia. PLoS One 10, e0117462 (2015).
48. Das, A., Patgiri, S. J., Saikia, L., Dowerah, P. & Nath, R. Bacterial pathogens associated with community-acquired pneumonia in children aged below five years. Indian Pediatr. 53, 225-227 (2016).
49. Young Infants Clinical Signs Study Group. Clinical signs that predict severe illness in children under age 2 months: a multicentre study. Lancet 371, 135-142 (2008).
50. Carlo, W. A. et al. Newborn-care training and perinatal mortality in developing countries. N. Engl. J. Med. 362, 614-623 (2010).
51. Panigrahi, P. et al. Neonatal sepsis in rural India: timing, microbiology and antibiotic resistance in a population-based prospective study in the community setting. J. Perinatal. http://dx.doi.org/10.1038/jp.2017.67 (2017).