Cardioprotection mediated by exosomes is impaired in the setting of type II diabetes but can be rescued by the use of non-diabetic exosomes in vitro

Journal of Cellular and Molecular Medicine

Volumn 22, Issue 1, 2018, Pages 141-151

  Davidson, Sean M ^a   Riquelme, Jaime A ^a,b   Takov, Kaloyan ^a   Vicencio, Jose M ^a   Boi Doku, Claire ^a   Khoo, Vanessa ^a   Doreth, Christian ^a   Radenkovic, Dina ^a   Lavandero, Sergio ^b   Yellon, Derek M ^a  

^a UNIVERSITY COLLEGE LONDON   (United Kingdom)

^b UNIVERSITY OF CHILE   (Chile)

Author keywords

cardioprotection; diabetes; Exosomes; ischaemia; reperfusion

Indexed keywords

CD81 ANTIGEN; HEAT SHOCK PROTEIN 27; HEAT SHOCK PROTEIN 70; MITOGEN ACTIVATED PROTEIN KINASE 1; MITOGEN ACTIVATED PROTEIN KINASE 3; NANOPARTICLE; CARDIOTONIC AGENT; MITOGEN ACTIVATED PROTEIN KINASE;

ACUTE HEART INFARCTION; ADULT; AGED; ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CARDIAC MUSCLE CELL; CONTROLLED STUDY; ENDOTHELIUM CELL; EXOSOME; EXPERIMENTAL HYPERGLYCEMIA; FLOW CYTOMETRY; HEART PROTECTION; HISTOPATHOLOGY; HUMAN; HUMAN CELL; HUMAN VERSUS ANIMAL COMPARISON; HYPOXIA; IMMUNOHISTOCHEMISTRY; MALE; NON INSULIN DEPENDENT DIABETES MELLITUS; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; RAT; REOXYGENATION; TRANSMISSION ELECTRON MICROSCOPY; WESTERN BLOTTING; ANIMAL; CHEMISTRY; METABOLISM; MIDDLE AGED; PATHOLOGY; PHOSPHORYLATION; ULTRASTRUCTURE; UMBILICAL VEIN ENDOTHELIAL CELL; VERY ELDERLY; WISTAR RAT;

AGED; AGED, 80 AND OVER; ANIMALS; CARDIOTONIC AGENTS; DIABETES MELLITUS, TYPE 2; EXOSOMES; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HSP27 HEAT-SHOCK PROTEINS; HSP70 HEAT-SHOCK PROTEINS; HUMAN UMBILICAL VEIN ENDOTHELIAL CELLS; HUMANS; MALE; MIDDLE AGED; MYOCYTES, CARDIAC; NANOPARTICLES; PHOSPHORYLATION; RATS, WISTAR; TETRASPANIN 28;

EID: 85028323570     PISSN: 15821838     EISSN: None     Source Type: Journal    
DOI: 10.1111/jcmm.13302     Document Type: Article

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