Multifunctional 5-aminolevulinic acid prodrugs activating diverse cell-death pathways

Investigational New Drugs

Volumn 30, Issue 3, 2012, Pages 1028-1038

  Berkovitch Luria, Gili ^a   Weitman, Michal ^a   Nudelman, Abraham ^a   Rephaeli, Ada ^b   Malik, Zvi ^a  

^a BAR ILAN UNIVERSITY   (Israel)

^b TEL AVIV UNIVERSITY   (Israel)

Author keywords

5 aminolevulinic acid prodrugs; Glioblastoma U251; Photodynamic therapy; Porphobilinogen deaminase

Indexed keywords

AMINOLEVULINIC ACID ACETALDEHYDE BUTYRIC ACID; AMINOLEVULINIC ACID ACETALDEHYDE PIVALIC ACID; AMINOLEVULINIC ACID FORMALDEHYDE BUTYRIC ACID; AMINOLEVULINIC ACID FORMALDEHYDE PIVALIC ACID; ANTINEOPLASTIC AGENT; HYDROLASE; PORPHOBILINOGEN DEAMINASE; PROTEASOME; PROTOPORPHYRIN; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; CELL DEATH; CELL METABOLISM; CONTROLLED STUDY; DRUG CYTOTOXICITY; DRUG STRUCTURE; ENDOPLASMIC RETICULUM; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME RELEASE; GLIOBLASTOMA; HUMAN; HUMAN CELL; MITOCHONDRIAL MEMBRANE POTENTIAL; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCANNING ELECTRON MICROSCOPY; SIGNAL TRANSDUCTION; UPREGULATION;

EID: 85027947805     PISSN: 01676997     EISSN: 15730646     Source Type: Journal    
DOI: 10.1007/s10637-011-9669-6     Document Type: Article

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