Cardiorespiratory fitness determines the reduction in blood pressure and insulin resistance during lifestyle intervention

Journal of Hypertension

Volumn 29, Issue 6, 2011, Pages 1220-1227

  Totsikas, Charisis ^a   Röhm, Julian ^a   Kantartzis, Konstantinos ^a   Thamer, Claus ^a   Rittig, Kilian ^a   MacHann, Jürgen ^b   Schick, Fritz ^b   Hansel, Jochen ^c   Niess, Andreas ^c   Fritsche, Andreas ^a   Häring, Hans Ulrich ^a   Stefan, Norbert ^a  

^a GERMAN CENTER FOR DIABETES RESEARCH DZD   (Germany)

^b Section of Experimental Radiology   (Germany)

^c UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

blood pressure; cardiorespiratory fitness; hypertension; insulin resistance; lifestyle intervention; obesity

Indexed keywords

CHOLESTEROL; GLUCOSE; HIGH DENSITY LIPOPROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN; TRIACYLGLYCEROL;

AEROBIC CAPACITY; AEROBIC EXERCISE; AGED; ARTICLE; BODY FAT; CARDIOPULMONARY FUNCTION; CARDIORESPIRATORY FITNESS; CARDIOVASCULAR RISK; DIASTOLIC BLOOD PRESSURE; FEMALE; GLUCOSE BLOOD LEVEL; HUMAN; HYPERTENSION; INSULIN RESISTANCE; INSULIN SENSITIVITY; INTRAABDOMINAL FAT; LIFESTYLE MODIFICATION; LIPID BLOOD LEVEL; MAJOR CLINICAL STUDY; MALE; OBESITY; ORAL GLUCOSE TOLERANCE TEST; PHYSICAL ACTIVITY; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; SYSTOLIC BLOOD PRESSURE; TREADMILL EXERCISE;

EID: 85027933385     PISSN: 02636352     EISSN: None     Source Type: Journal    
DOI: 10.1097/HJH.0b013e3283469910     Document Type: Article

References (43)

1. Lewington S, Clarke R, Qizilbash N, Peto R, Collins R. Age-specific relevance of usual blood pressure to vascular mortality: a meta-analysis of individual data for one million adults in 61 prospective studies. Lancet 2002; 360:1903-1913. (Pubitemid 35472129)
2. Gu D, Chen J, Wu X, Duan X, Jones DW, Huang JF, et al. Prehypertension and risk of cardiovascular disease in Chinese adults. J Hypertens 2009; 27:721-729.
3. Toprak A, Wang H, Chen W, Paul T, Ruan L, Srinivasan S, et al. Prehypertension and black-white contrasts in cardiovascular risk in young adults: Bogalusa Heart Study. J Hypertens 2009; 27:243-250.
4. Zhou MS, Schulman IH. Prevention of diabetes in hypertensive patients: results and implications from the VALUE trial. Vasc Health Risk Manag 2009; 5:361-368.
5. Giunti S, Cooper M. Does the metabolic syndrome make blood pressure control more difficult in diabetes? J Hypertens 2005; 23:2155-2156. (Pubitemid 41666744)
6. Ferrannini E, Buzzigoli G, Bonadonna R, Giorico MA, Oleggini M, Graziadei L, et al. Insulin resistance in essential hypertension. N Engl J Med 1987; 317:350-357. (Pubitemid 17118813)
7. Bonora E, TargherG, Alberiche M, Bonadonna RC, Zenere MB, Saggiani F, et al. Intracellular partition of plasma glucose disposal in hypertensive and normotensive subjects with type 2 diabetes mellitus. J Clin Endocrinol Metab 2001; 86:2073-2079. (Pubitemid 32472922)
8. Cifkova R, Nilsson PM. Statins and hypertension. J Hypertens 2009; 27:662-665.
9. Grundy SM, Cleeman JI, Daniels SR, Donato KA, Eckel RH, Franklin BA, et al. Diagnosis and management of the metabolic syndrome: an American Heart Association/National Heart, Lung, and Blood Institute Scientific Statement. Circulation 2005; 112:2735-2752. (Pubitemid 41532612)
10. Appel LJ, Moore TJ, Obarzanek E, Vollmer WM, Svetkey LP, Sacks FM, et al. A clinical trial of the effects of dietary patterns on blood pressure. DASH Collaborative Research Group. N Engl J Med 1997; 336:1117-1124.
11. Lien LF, Brown AJ, Ard JD, Loria C, Erlinger TP, Feldstein AC, et al. Effects of PREMIER lifestyle modifications on participants with and without the metabolic syndrome. Hypertension 2007; 50:609-616. (Pubitemid 47442722)
12. Ilanne-Parikka P, Eriksson JG, Lindstrom J, Peltonen M, Aunola S, Hamalainen H, et al. Effect of lifestyle intervention on the occurrence of metabolic syndrome and its components in the Finnish Diabetes Prevention Study. Diabetes Care 2008; 31:805-807.
13. Orchard TJ, Temprosa M, Goldberg R, Haffner S, Ratner R, Marcovina S, et al. The effect of metformin and intensive lifestyle intervention on the metabolic syndrome: the Diabetes Prevention Program randomized trial. Ann Intern Med 2005; 142:611-619. (Pubitemid 40529957)
14. Whelton SP, Chin A, Xin X, He J. Effect of aerobic exercise on blood pressure: a meta-analysis of randomized, controlled trials. Ann Intern Med 2002; 136:493-503. (Pubitemid 34252283)
15. Aucott L, Poobalan A, Smith WC, Avenell A, Jung R, Broom J. Effects of weight loss in overweight/obese individuals and long-term hypertension outcomes: a systematic review. Hypertension 2005; 45:1035-1041. (Pubitemid 40770300)
16. Dickinson HO, Mason JM, Nicolson DJ, Campbell F, Beyer FR, Cook JV, et al. Lifestyle interventions to reduce raised blood pressure: a systematic review of randomized controlled trials. J Hypertens 2006; 24:215-233.
17. Aucott L, Rothnie H, McIntyre L, Thapa M, Waweru C, Gray D. Long-term weight loss from lifestyle intervention benefits blood pressure?: a systematic review. Hypertension 2009; 54:756-762.
18. Kuller LH. Weight loss and reduction of blood pressure and hypertension. Hypertension 2009; 54:700-701.
19. Blair SN, Kohl HW III, Paffenbarger RS Jr, Clark DG, Cooper KH, Gibbons LW. Physical fitness and all-cause mortality. A prospective study of healthy men and women. JAMA 1989; 262:2395-2401. (Pubitemid 19261810)
20. Wei M, Kampert JB, Barlow CE, Nichaman MZ, Gibbons LW, Paffenbarger RS Jr, et al. Relationship between low cardiorespiratory fitness and mortality in normal-weight, overweight, and obese men. JAMA 1999; 282:1547-1553. (Pubitemid 29504048)
21. Church TS, Kampert JB, Gibbons LW, Barlow CE, Blair SN. Usefulness of cardiorespiratory fitness as a predictor of all-cause and cardiovascular disease mortality in men with systemic hypertension. Am J Cardiol 2001; 88:651-656. (Pubitemid 32834042)
22. Laukkanen JA, Lakka TA, Rauramaa R, Kuhanen R, Venalainen JM, Salonen R, et al. Cardiovascular fitness as a predictor of mortality in men. Arch Intern Med 2001; 161:825-831. (Pubitemid 32225390)
23. Stefan N, Thamer C, Staiger H, Machicao F, Machann J, Schick F, et al. Genetic variations in PPARD and PPARGC1A determine mitochondrial function and change in aerobic physical fitness and insulin sensitivity during lifestyle intervention. J Clin Endocrinol Metab 2007; 92:1827-1833. (Pubitemid 46997196)
24. Kantartzis K, Thamer C, Peter A, Machann J, Schick F, Schraml C, et al. High cardiorespiratory fitness is an independent predictor of the reduction in liver fat during a lifestyle intervention in nonalcoholic fatty liver disease. Gut 2009; 58:1281-1288.
25. Stefan N, Machicao F, Staiger H, Machann J, Schick F, Tschritter O, et al. Polymorphisms in the gene encoding adiponectin receptor 1 are associated with insulin resistance and high liver fat. Diabetologia 2005; 48:2282-2291. (Pubitemid 41618919)
26. Pischon T, Boeing H, Hoffmann K, Bergmann M, Schulze MB, Overvad K, et al. General and abdominal adiposity and risk of death in Europe. N Engl J Med 2008; 359:2105-2120.
27. Tuomilehto J, Lindstrom J, Eriksson JG, Valle TT, Hamalainen H, Ilanne- Parikka P, et al. Prevention of type 2 diabetes mellitus by changes in lifestyle among subjects with impaired glucose tolerance. N Engl J Med 2001; 344:1343-1350. (Pubitemid 32378388)
28. Baecke JA, Burema J, Frijters JE. A short questionnaire for the measurement of habitual physical activity in epidemiological studies. Am J Clin Nutr 1982; 36:936-942. (Pubitemid 13214364)
29. Matsuda M, DeFronzo RA. Insulin sensitivity indices obtained from oral glucose tolerance testing: comparison with the euglycemic insulin clamp. Diabetes Care 1999; 22:1462-1470. (Pubitemid 29418240)
30. Roecker K, Schotte O, Niess AM, Horstmann T, Dickhuth HH. Predicting competition performance in long-distance running by means of a treadmill test. Med Sci Sports Exerc 1998; 30:1552-1557. (Pubitemid 28465523)
31. Porszasz J, Casaburi R, Somfay A, Woodhouse LJ, Whipp BJ. A treadmill ramp protocol using simultaneous changes in speed and grade. Med Sci Sports Exerc 2003; 35:1596-1603. (Pubitemid 37087592)
32. Stefan N, Kantartzis K, Machann J, Schick F, Thamer C, Rittig K, et al. Identification and characterization of metabolically benign obesity in humans. Arch Intern Med 2008; 168:1609-1616.
33. Kantartzis K, Machann J, Schick F, Fritsche A, Haring HU, Stefan N. The impact of liver fat vs. visceral fat in determining categories of prediabetes. Diabetologia 2010; 53:882-889.
34. Pialoux V, Brown AD, Leigh R, Friedenreich CM, Poulin MJ. Effect of cardiorespiratory fitness on vascular regulation and oxidative stress in postmenopausal women. Hypertension 2009; 54:1014-1020.
35. Pescatello LS, Franklin BA, Fagard R, Farquhar WB, Kelley GA, Ray CA. American College of Sports Medicine position stand. Exercise and hypertension. Med Sci Sports Exerc 2004; 36:533-553.
36. Rankinen T, Church T, Rice T, Markward N, Leon AS, Rao DC, et al. Effect of endothelin 1 genotype on blood pressure is dependent on physical activity or fitness levels. Hypertension 2007; 50:1120-1125. (Pubitemid 350172935)
37. Barlow CE, LaMonte MJ, Fitzgerald SJ, Kampert JB, Perrin JL, Blair SN. Cardiorespiratory fitness is an independent predictor of hypertension incidence among initially normotensive healthy women. Am J Epidemiol 2006; 163:142-150. (Pubitemid 43068983)
38. Chase NL, Sui X, Lee DC, Blair SN. The association of cardiorespiratory fitness and physical activity with incidence of hypertension in men. Am J Hypertens 2009; 22:417-424.
39. Rheaume C, Arsenault BJ, Belanger S, Perusse L, Tremblay A, Bouchard C, et al.Lowcardiorespiratory fitness levels and elevated bloodpressure:what is the contribution of visceral adiposity? Hypertension 2009; 54:91-97.
40. Lindstrom J, Louheranta A, Mannelin M, Rastas M, Salminen V, Eriksson J, et al. The Finnish Diabetes Prevention Study (DPS): lifestyle intervention and 3-year results on diet and physical activity. Diabetes Care 2003; 26:3230-3236. (Pubitemid 37466880)
41. Siri-Tarino PW, Sun Q, Hu FB, Krauss RM. Saturated fat, carbohydrate, and cardiovascular disease. Am J Clin Nutr 2010; 91:502-509.
42. Duncan GE, Anton SD, Sydeman SJ, Newton RL Jr, Corsica JA, Durning PE, et al. Prescribing exercise at varied levels of intensity and frequency: a randomized trial. Arch Intern Med 2005; 165:2362-2369. (Pubitemid 41640848)
43. Kelley GA, Kelley KS, Tran ZV. Walking, lipids and lipoproteins: a metaanalysis of randomized controlled trials. Prev Med 2004; 38:651-661. (Pubitemid 38452892)