An engineered non-oxidative glycolysis pathway for acetone production in Escherichia coli

Biotechnology Letters

Volumn 38, Issue 8, 2016, Pages 1359-1365

  Yang, Xiaoyan ^a,b   Yuan, Qianqian ^a,b   Zheng, Yangyang ^b   Ma, Hongwu ^b   Chen, Tao ^a   Zhao, Xueming ^a  

^a TIANJIN UNIVERSITY   (China)

^b Tianjin Airport Economic Area   (China)

Author keywords

Acetone; Escherichia coli; Non oxidative glycolysis; Phosphoketolase

Indexed keywords

ESCHERICHIA COLI; GENE ENCODING; GENES; GLUCOSE; METABOLIC ENGINEERING; METABOLISM; PATHOLOGY;

AEROBIC CONDITION; BIFIDOBACTERIUM ADOLESCENTIS; COMPUTATIONAL ANALYSIS; FLUX BALANCE ANALYSIS; GENOME-SCALE METABOLIC NETWORK; METABOLIC NETWORK; NON-OXIDATIVE; PHOSPHOKETOLASE;

ACETONE;

ACETONE;

ESCHERICHIA COLI; GENETICS; GLYCOLYSIS; METABOLIC ENGINEERING; METABOLISM; PHYSIOLOGY;

ACETONE; ESCHERICHIA COLI; GLYCOLYSIS; METABOLIC ENGINEERING;

EID: 85027932586     PISSN: 01415492     EISSN: 15736776     Source Type: Journal    
DOI: 10.1007/s10529-016-2115-2     Document Type: Article

References (18)

1. Bermejo LL, Welker NE, Papoutsakis ET (1998) Expression of Clostridium acetobutylicum ATCC 824 genes in Escherichia coli for acetone production and acetate detoxification. Appl Environ Microbiol 64:1079–1085
2. Bogorad IW, Lin TS, Liao JC (2013) Synthetic non-oxidative glycolysis enables complete carbon conservation. Nature 502:693–698
3. Boynton ZL, Bennett GN, Rudolth FB (1994) Intracellular concentrations of coenzyme A and its derivatives from Clostridium acetobutylicum ATCC 824 and their roles in enzyme regulation. Appl Environ Microbiol 60:39–44
4. ε-lysine acetylation. Appl Microbiol Biotechnol 99:3533–3545
5. Chohnan S, Takamura Y (1991) A simple micromethod for measurement of CoASH and its use in measuring intracellular levels of CoASH and short chain Acyl-CoAs in Escherichia coli K12 cells. Agric Biol Chem 55:87–94
6. Hanai T, Atsumi S, Liao JC (2007) Engineered synthetic pathway for isopropanol production in Escherichia coli. Appl Environ Microbiol 73:7814–7818
7. Jones DT, Woods DR (1986) Acetone-butanol fermentation revisited. Microbiol Rev 40:484–524
8. Lin ZQ, Xu ZB, Li YF et al (2014) Metabolic engineering of Escherichia coli for the production of riboflavin. Microb Cell Fact 13:1–12
9. May A, Fischer RJ, Thum SM et al (2012) A modified pathway for the production of acetone in Escherichia coli. Metab Eng 15:218–225
10. McCleary WR, Stock JB, Ninfa AJ (1993) Is acetyl phosphate a global signal in Escherichia coli. J Bacteriol 175:2793–2798
11. Noguch S, Putri SP, Lan EI et al (2016) Quantitative target analysis and kinetic profiling of acyl-CoAs reveal the rate-limiting step in cyanobacterial 1-butanol production. Metabolomics 12:1–10
12. Orth JD, Conrad TM, Na J et al (2011) A comprehensive genome-scale reconstruction of Escherichia coli metabolism. Mol Syst Biol 7:1–9
13. Schellenberger J, Que R, Fleming RM et al (2011) Quantitative prediction of cellular metabolism with constraint based models: the COBRA Toolbox v2.0. Nat Protoc 6:1290–1307
14. Shi AQ, Zhu XN, Lu J, Zhang XL et al (2012) Activating transhydrogenase and NAD kinase in combination for improving isobutanol production. Metab Eng 16:1–10
15. Soma Y, Inokuma K, Tanaka T et al (2012) Direct isopropanol production from cellobiose by engineered Escherichia coli using a synthetic pathway and a cell surface display system. J Biosci Bioeng 114:80–85
16. Vadali RV, Bennett GN, San KY (2004) Cofactor engineering of intracellular CoA/acetyl-CoA and its effect on metabolic flux redistribution in Escherichia coli. Metab Eng 6:133–139
17. Wendisch VF, Spies M, Reinscheid DJ et al (1997) Regulation of acetate metabolism in Corynebacterium glutamicum: transcriptional control of the isocitrate lyase and malate synthase genes. Arch Microbiol 168:262–269
18. Zhu NQ, Xia HH, Wang ZW et al (2013) Engineering of acetate recycling and citrate synthase to improve aerobic succinate production in Corynebacterium glutamicum. PLoS ONE 8:1–8