Developmental Programming of O2 Sensing By Neonatal Intermittent Hypoxia via Epigenetic Mechanisms

Respiratory Physiology and Neurobiology

Volumn 185, Issue 1, 2013, Pages 105-109

  Nanduri, Jayasri ^a   Prabhakar, Nanduri R ^a  

^a University of Chicago   (United States)

Author keywords

Apnea of prematurity; cardio respiratory morbidities; DNA methylation; exocytosis; histone modifications; neurotransmitters modulators; oxidative stress

Indexed keywords

OXYGEN;

ADRENAL MEDULLA; ANIMAL; BLOOD; CAROTID BODY; CHROMAFFIN CELL; FETUS HYPOXIA; GENETIC EPIGENESIS; GENETICS; HUMAN; NEWBORN; PHYSIOLOGY; PREMATURITY; REVIEW;

ADRENAL MEDULLA; ANIMALS; ANIMALS, NEWBORN; CAROTID BODY; CHROMAFFIN CELLS; EPIGENESIS, GENETIC; FETAL HYPOXIA; HUMANS; INFANT, NEWBORN; INFANT, PREMATURE; OXYGEN;

MLCS; MLOWN;

EID: 85027931873     PISSN: 15699048     EISSN: 18781519     Source Type: Journal    
DOI: 10.1016/j.resp.2012.07.016     Document Type: Review

References (38)

1. Abu-Shaweesh, J.M., Martin, R.J., Neonatal apnea: what's new?. Pediatr Pulmonol 43 (2008), 937–944.
2. Ambrosio, G., Tritto, I., Chiariello, M., The role of oxygen free radicals in preconditioning. J Mol Cell Cardiol. 27 (1995), 1035–1039.
3. Aracena, P., Sánchez, G., Donoso, P., Hamilton, S.L., Hidalgo, C., S-glutathionylation decreases Mg2+ inhibition and S-nitrosylation enhances Ca2+ activation of RyR1 channels. J. Biol. Chem. 278 (2003), 42927–42935.
4. Bedard, K., Krause, K.H., The NOX family of ROS-generating NADPH oxidases: physiology and pathophysiology. Physiol. Rev 87 (2007), 245–313.
5. Blanco, C.E., Dawes, G.S., Hanson, M.A., McCooke, H.B., The response to hypoxia of arterial chemoreceptors in fetal sheep and new-born lambs. J. Physiol. 351 (1984), 25–37.
6. Carroll, J.L., Developmental plasticity in respiratory control. J. Appl. Physiol. 94 (2003), 375–389.
7. Chen, J., He, L., Dinger, B., Fidone, S., Cellular mechanisms involved in rabbit carotid body excitation elicited by endothelin peptides. Respir Physiol. 121 (2000), 13–23.
8. Dalziel, S.R., Parag, V., Rodgers, A., Harding, J.E., Cardiovascular risk factors at age 30 following pre-term birth. Int. J. Epidemiol 36 (2007), 907–915.
9. Del Rio, R., Moya, E.A., Iturriaga, R., Differential expression of pro-inflammatory cytokines, endothelin-1 and nitric oxide synthases in the rat carotid body exposed to intermittent hypoxia. Brain Res. 1395 (2011), 74–85.
10. Donnelly, D.F., Developmental aspects of oxygen sensing by the carotid body. J. Appl. Physiol. 88 (2000), 2296–2301.
11. Donnelly, D.F., Doyle, T.P., Hypoxia-induced catecholamine release from rat carotid body, in vitro, during maturation and following chronic hypoxia. Adv Exp Med Biol. 360 (1994), 197–199.
12. Feinberg, A.P., Phenotypic plasticity and the epigenetics of human disease. Nature 447 (2007), 433–440.
13. Hibbs, A.M., Johnson, N.L., Rosen, C.L., Kirchner, H.L., Martin, R., Storfer-Isser, A., Redline, S., Prenatal and neonatal risk factors for sleep disordered breathing in school-aged children born preterm. J. Pediatr. 153 (2008), 176–182.
14. Hiroshi, O., Nobuko, O., Kunio, Y., Assay for lipid peroxidases in animal tissues by thiobarbituric acid reaction. Analytical Biochemistry. 95 (1979), 351–358.
15. Julien, C., Bairam, A., Joseph, V., Chronic intermittent hypoxia reduces ventilatory long-term facilitation and enhances apnea frequency in newborn rats. Am. J. Physiol. Regul. Integr. Comp. Physiol 294 (2008), R1356–R1366.
16. Julien, C., Joseph, V., Bairam, A., Alteration of carotid body chemoreflexes after neonatal intermittent hypoxia and caffeine treatment in rat pups. Respir Physiol Neurobiol. 177 (2011), 301–312.
17. Kumar, P., Prabhakar, N.R., Peripheral Chemoreceptors: Function and Plasticity of the carotid body. Comprehensive Physiology. 2 (2012), 141–219.
18. Lagercrantz, H., Bistoletti, P., Catecholamine release in the newborn infant at birth. Pediatr. Res. 11 (1977), 889–893.
19. Lagercrantz, H., Edwards, D., Henderson-Smart, D., Hertzberg, T., Jeffery, H., Autonomic reflexes in preterm infants. Acta Paediatr Scand. 79 (1990), 721–728.
20. Lagercrantz, H., Sjöquist, B., Deficient sympatho-adrenal activity-a cause of apnoea? Urinary excretion of catecholamines and their metabolites in preterm infants. Early Hum Dev 4 (1980), 405–409.
21. Nanduri, J., Makarenko, V., Reddy, V.D., Yuan, G., Pawar, A., Wang, N., Khan, S.A., Zhang, X., Kinsman, B., Peng, Y.J., Kumar, G.K., Fox, A.P., Godley, L.A., Semenza, G.L., Prabhakar, N.R., Epigenetic regulation of hypoxic sensing disrupts cardiorespiratory homeostasis. Proc. Natl. Acad. Sci. U. S. A. 109 (2012), 2515–2520.
22. Nock, M.L., Difiore, J.M., Arko, M.K., Martin, R.J., Relationship of the ventilatory response to hypoxia with neonatal apnea in preterm infants. J. Pediatr. 144 (2004), 291–295.
23. Paavonen, E.J., Strang-Karlsson, S., Räikkönen, K., Heinonen, K., Pesonen, A.K., Hovi, P., Andersson, S., Järvenpää, A.L., Eriksson, J.G., Kajantie, E., Very low birth weight increases risk for sleep-disordered breathing in young adulthood: the Helsinki Study of Very Low Birth Weight Adults. Pediatrics 120 (2007), 778–784.
24. Pawar, A., Nanduri, J., Yuan, G., Khan, S.A., Wang, N., Kumar, G.K., Prabhakar, N.R., Reactive oxygen species-dependent endothelin signaling is required for augmented hypoxic sensory response of the neonatal carotid body by intermittent hypoxia. Am. J. Physiol. Regul. Integr. Comp. Physiol 296 (2009), R735–R742.
25. Pawar, A., Peng, Y.J., Jacono, F.J., Prabhakar, N.R., Comparative analysis of neonatal and adult rat carotid body responses to chronic intermittent hypoxia. J. Appl. Physiol. 104 (2008), 1287–1294.
26. Peng, Y.J., Overholt, J.L., Kline, D., Kumar, G.K., Prabhakar, N.R., Induction of sensory long-term facilitation in the carotid body by intermittent hypoxia: implications for recurrent apneas. Proc. Natl. Acad. Sci. U.S.A. 100 (2003), 10073–10078.
27. Peng, Y.J., Rennison, J., Prabhakar, N.R., Intermittent hypoxia augments carotid body and ventilatory response to hypoxia in neonatal rat pups. J. Appl. Physiol. 97 (2004), 2020–2025.
28. Poets, C.F., Samuels, M.P., Southall, D.P., Epidemiology and pathophysiology of apnoea of prematurity. Biol. Neonate. 65 (1994), 211–219.
29. Rey, S., Iturriaga, R., Endothelins and nitric oxide: vasoactive modulators of carotid body chemoreception. Curr. Neurovasc. Res. 1 (2004), 465–473.
30. Rosen, C.L., Larkin, E.K., Kirchner, H.L., Emancipator, J.L., Bivins, S.F., Surovec, S.A., Martin, R.J., Redline, S., Prevalence and risk factors for sleep-disordered breathing in 8- to 11-year-old children: association with race and prematurity. J. Pediatr. 142 (2003), 383–389.
31. Seidler, F.J., Slotkin, T.A., Adrenomedullary function in the neonatal rat: responses to acute hypoxia. J. Physiol. 358 (1985), 1–16.
32. Seidler, F.J., Slotkin, T.A., Non-neurogenic adrenal catecholamine release in the neonatal rat: exocytosis or diffusion?. Brain. Res 393 (1986), 274–277.
33. Souvannakitti, D., Kumar, G.K., Fox, A., Prabhakar, N.R., Neonatal intermittent hypoxia leads to long-lasting facilitation of acute hypoxia-evoked catecholamine secretion from rat chromaffin cells. J. Neurophysiol. 101 (2009), 2837–2846.
34. Souvannakitti, D., Nanduri, J., Yuan, G., Kumar, G.K., Fox, A.P., Prabhakar, N.R., NADPH oxidase-dependent regulation of T-type Ca2+ channels and ryanodine receptors mediate the augmented exocytosis of catecholamines from intermittent hypoxia-treated neonatal rat chromaffin cells. J. Neurosci. 30 (2010), 10763–10772.
35. Sterni, L.M., Bamford, O.S., Wasicko, M.J., Carroll, J.L., Chronic hypoxia abolished the postnatal increase in carotid body type I cell sensitivity to hypoxia. Am. J. Physiol. 277 (1999), L645–L652.
36. Takeuchi, Y., Mochizuki-Oda, N., Yamada, H., Kurokawa, K., Watanabe, Y., Nonneurogenic hypoxia sensitivity in rat adrenal slices. Biochem. Biophys. Res. Commun. 289 (2001), 51–56.
37. Thompson, R.J., Jackson, A., Nurse, C.A., Developmental loss of hypoxic chemosensitivity in rat adrenomedullary chromaffin cells. J. Physiol. 498:Pt 2 (1997), 503–510.
38. Yokotani, K., Okada, S., Nakamura, K., Characterization of functional nicotinic acetylcholine receptors involved in catecholamine release from the isolated rat adrenal gland. Eur. J. Pharmacol. 446 (2002), 83–87.