Do mitochondria donate membrane to form autophagosomes or undergo remodeling to form mitochondrial spheroids?

Cell and Bioscience

Volumn 4, Issue 1, 2014, Pages

  Ding, Wen Xing ^a   Eskelinen, Eeva Liisa ^b  

^a UNIVERSITY OF KANSAS SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF HELSINKI   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 85027931120     PISSN: None     EISSN: 20453701     Source Type: Journal    
DOI: 10.1186/2045-3701-4-65     Document Type: Letter

References (11)

1. Cook KL, Soto-Pantoja DR, Abu-Asab M, Clarke PA, Roberts DD, Clarke R: Mitochondria directly donate their membrane to form autophagosomes during a novel mechanism of parkin-associated mitophagy. Cell Biosci 2014, 4:16 10.1186/2045-3701-4-16.
2. Ding WX, Guo F, Ni HM, Bockus A, Manley S, Stolz DB, Eskelinen EL, Jaeschke H, Yin XM: Parkin and mitofusins reciprocally regulate mitophagy and mitochondrial spheroid formation. J Biol Chem 2012, 287:42379-42388. 10.1074/jbc.M112.413682
3. Ding WX, Li M, Biazik JM, Morgan DG, Guo F, Ni HM, Goheen M, Eskelinen EL, Yin XM: Electron microscopic analysis of a spherical mitochondrial structure. J Biol Chem 2012, 287:42373-42378 10.1074/jbc.M112.413674.
4. Yin XM, Ding WX: The reciprocal roles of PARK2 and mitofusins in mitophagy and mitochondrial spheroid formation. Autophagy 2013, 9:1687-1692 10.4161/auto.24871.
5. Yamano K, Youle RJ: PINK1 is degraded through the N-end rule pathway. Autophagy 2013, 9:1758-1769 10.4161/auto.24633.
6. Lazarou M, Jin SM, Kane LA, Youle RJ: Role of PINK1 binding to the TOM complex and alternate intracellular membranes in recruitment and activation of the E3 ligase Parkin. Dev Cell 2012, 22:320-333 10.1016/j.devcel.2011.12.014.
7. Jin SM, Youle RJ: PINK1- and Parkin-mediated mitophagy at a glance. J Cell Sci 2012, 125:795-799 10.1242/jcs.093849.
8. Xu L, Lin DC, Yin D, Koeffler HP: An emerging role of PARK2 in cancer. J Mol Med (Berl) 2014, 92:31-42 10.1007/s00109-013-1107-0.
9. Ding WX, Ni HM, Li M, Liao Y, Chen X, Stolz DB, Dorn GW 2nd, Yin XM: Nix is critical to two distinct phases of mitophagy, reactive oxygen species-mediated autophagy induction and Parkin-ubiquitin-p62-mediated mitochondrial priming. J Biol Chem 2010, 285:27879-27890 10.1074/jbc.M110.119537.
10. Gong Y, Zack TI, Morris LG, Lin K, Hukkelhoven E, Raheja R, Tan IL, Turcan S, Veeriah S, Meng S, Viale A, Schumacher SE, Palmedo P, Beroukhim R, Chan TA: Pan-cancer genetic analysis identifies PARK2 as a master regulator of G1/S cyclins. Nat Genet 2014, 46:588-594 10.1038/ng.2981.
11. Narendra D, Tanaka A, Suen DF, Youle RJ: Parkin is recruited selectively to impaired mitochondria and promotes their autophagy. J Cell Biol 2008, 183:795-803. 10.1083/jcb.200809125