From laryngeal epithelial precursor lesions to squamous carcinoma of the larynx: the role of cell cycle proteins and b-catenin

European Archives of Oto-Rhino-Laryngology

Volumn 270, Issue 12, 2013, Pages 3153-3162

  López, Fernando ^a   Álvarez Marcos, César ^a   Alonso Guervós, Marta ^a   Domínguez, Francisco ^b   Suárez, Carlos ^a   Hermsen, Mario A ^a   Llorente, José L ^a  

^a DEPARTAMENTO DE BIOQUÍMICA Y BIOLOGÍA MOLECULAR   (Spain)

^b HOSPITAL DE CABUEÑES   (Spain)

Author keywords

Carcinoma; Dysplasia; Epithelial precursor lesions; Immunohistochemical study; Larynx

Indexed keywords

BETA CATENIN; CELL CYCLE PROTEIN; TUMOR MARKER;

ADULT; AGED; ARTICLE; BIOPSY; DISEASE COURSE; FEMALE; HUMAN; IMMUNOHISTOCHEMISTRY; LARYNX TUMOR; MALE; METABOLISM; MIDDLE AGED; PATHOLOGY; PRECANCER; RETROSPECTIVE STUDY; SQUAMOUS CELL CARCINOMA; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; BETA CATENIN; BIOPSY; CARCINOMA, SQUAMOUS CELL; CELL CYCLE PROTEINS; DISEASE PROGRESSION; FEMALE; HUMANS; IMMUNOHISTOCHEMISTRY; LARYNGEAL NEOPLASMS; MALE; MIDDLE AGED; PRECANCEROUS CONDITIONS; RETROSPECTIVE STUDIES; TUMOR MARKERS, BIOLOGICAL;

EID: 85027922138     PISSN: 09374477     EISSN: 14344726     Source Type: Journal    
DOI: 10.1007/s00405-013-2476-2     Document Type: Article

References (35)

1. Califano J, van der Riet P, Westra W, Nawroz H, Clayman G, Piantadosi S et al (1996) Genetic progression model for head and neck cancer: implications for field cancerization. Cancer Res 56:2488–2492
2. Rodrigo JP, García Pedrero JM, Suárez C, Takes RP, Thompson LDR, Sloootweg PJ et al (2012) Biomarkers predicting malignant progression of laryngeal epithelial precursor lesion: a systematic review. Eur Arch Otolaryngol 269:1073–1083
3. Papadimitrakopoulou V, Izzo JG, Liu DD, Myers J, Ceron TL, Lewin J et al (2009) Cyclin D1 and cancer development in laryngeal premalignancy patients. Cancer Prev Res 2:14–21
4. Mirza S, Jeannon JP, Soames J, Wilson JA (2006) Is Ki67 a marker for the transformation of laryngeal dysplasia to carcinoma? Acta Otolaryngol 126:418–421
5. Visser R, van der Beek JM, Havenith MG, Cleutjens JP, Bosman FT (1986) Immunocytochemical detection of basement membrane antigens in the histopathological evaluation of laryngeal dysplasia and neoplasia. Histopathology 10:171–180
6. Rodrigo JP, Domínguez F, Álvarez C, Manrique C, Herrero A, Suárez C (2002) Expression of E-cadherin in squamous cell carcinomas of the supraglottic larynx with correlations to clinicopathological features. Eur J Cancer 38:1059–1064
7. Remacle M, Eckel HE, Antonelli A, Brasnu D, Chevalier D, Friedrich G et al (2000) Endoscopic cordectomy. A proposal for a classification by the Working Committee, European Laryngological Society. Eur Arch Otorhinolaryngol 257:227–231
8. Cruz I, Napier SS, van der Waal I, Snijders PJ, Walboomers JM, Lamey PJ et al (2002) Suprabasal p53 immunoexpression is strongly associated with high grade dysplasia and risk for malignant transformation in potentially malignant oral lesions from Northern Ireland. J Clin Pathol 55:98–104
9. Geradts J, Wilson PA (1996) High frequency of aberrant p16(INK4A) expression in human breast cancer. Am J Pathol 149:15–20
10. Jeannon JP, Soames JV, Aston V, Stafford FW, Wilson JA (2004) Molecular markers in dysplasia of the larynx: expression of cyclin-dependent kinase inhibitors p21, p27 and p53 tumour suppressor gene in predicting cancer risk. Clin Otolaryngol Allied Sci 29:698–704
11. Fan GK, Fujieda S, Sunaga H, Tsuzuki H, Ito N, Saito H (1999) Expression of protein p27 is associated with progression and prognosis in laryngeal cancer. Laryngoscope 109:815–820
12. Rodrigo JP, Álvarez-Alija G, Menéndez ST, Mancebo G, Allonca E, García-Carracedo D et al (2011) Cortactin and focal adhesion kinase as predictors of cancer risk in patients with laryngeal premalignancy. Cancer Prev Res 4:1333–1341
13. Mielcarek-Kuchta D, Olofsson J, Golusinski W (2008) Laminin expression in advanced laryngeal squamous cell carcinoma does not correlate to neck metastases. Eur Arch Otorhinolaryngol 265:1257–1261
14. Hsu PK, Li AF, Wang YC, Hsieh CC, Huang MH, Hsu WH et al (2008) Reduced membranous beta-catenin protein expression is associated with metastasis and poor prognosis in squamous cell carcinoma of the esophagus. J Thorac Cardiovasc Surg 135:1029–1035
15. Pignataro L, Capaccio P, Pruneri G, Carboni N, Buffa R, Neri A et al (1998) The predictive value of p53, MDM-2, cyclin D1 and Ki67 in the progression from low-grade dysplasia towards carcinoma of the larynx. J Laryngol Otol 112:455–459
16. Cabanillas R, Rodrigo JP, Ferlito A, Rinaldo A, Fresno MF, Aguilar C et al (2007) Is there an epidemiological link between human papillomavirus DNA and basaloid squamous cell carcinoma of the pharynx? Oral Oncol 43:327–332
17. Gale N, Michaels L, Luzar B, Poljak M, Zidar N, Fischinger J et al (2009) Current review on squamous intraepithelial lesions of the larynx. Histopathology 54:639–656
18. Eversole LR (2009) Dysplasia of the upper aerodigestive tract squamous epithelium. Head Neck Pathol 3:63–68
19. Sadri M, McMahon J, Parker A (2006) Management of laryngeal dysplasia: a review. Eur Arch Otorhinolaryngol 263:843–852
20. Zhang HK, Liu HG (2012) Is severe dysplasia the same lesion as carcinoma in situ? 10-Year follow-up of laryngeal precancerous lesions. Acta Otolaryngol 132:325–328
21. Rodrigo JP, García-Carracedo D, García LA, Menéndez S, Allonca E, González MV et al (2009) Distinctive clinicopathological associations of amplification of the cortactin gene at 11q13 in head and neck squamous cell carcinomas. J Pathol 217:516–523
22. a Gil-Carcedo García, Jaime Marco, Jesús E. Medina, Primitivo Ortega, Juan Trinidad (eds) Tratado de otorrinolaringología y cirugía de cabeza y cuello, 2nd edn. Panamericana, Madrid
23. Leemans CR, Braakhuis BJ, Brakenhoff RH (2011) The molecular biology of head and neck cancer. Nat Rev Cancer 11:9–22
24. Boyle JO, Hakim J, Koch W, van der Riet P, Hruban RH, Roa RA et al (1993) The incidence of p53 mutations increases with progression of head and neck cancer. Cancer Res 53:4477–4480
25. Gallo O, Santucci M, Franchi A (1997) Cumulative prognostic value of p16/CDKN2 and p53 oncoprotein expression in pre-malignant laryngeal lesions. J Natl Cancer Inst 89:1161–1163
26. Braakhuis BJM, Tabor MP, Kummer JA, Kummer A, Leemans R, Brakenhoff RH (2003) A genetic explanation of Slaughter’s concept of field cancerization. Cancer Res 63:1727–1730
27. Marcos CÁ, Alonso-Guervós M, Prado NR, Gimeno TS, Iglesias FD, Hermsen M et al (2011) Genetic model of transformation and neoplastic progression in laryngeal epithelium. Head Neck 33: 216–224
28. Li X, Gao L, Li H, Gao J, Yang Y, Zhou F et al (2013) Human papillomavirus infection and laryngeal cancer risk: a systematic review and meta-analysis. J Infect Dis 207:479–488
29. Mehanna H, Beech T, Nicholson T, El-Hariry I, McConkey C, Paleri V, et al (2012) Prevalence of human papillomavirus in oropharyngeal and nonoropharyngeal head and neck cancer-systematic review and meta-analysis of trends by time and region. Head Neck doi:10.1002/hed.22015 (Epub ahead of print)
30. Schoelch ML, Regezi JA, Dekker NP, Ng IO, McMillan A, Ziober BL et al (1999) Cell cycle proteins and the development of oral squamous cell carcinoma. Oral Oncol 35:333–342
31. Nusse R (2005) Wnt signaling in disease and in development. Cell Res 15:28–32
32. Galera-Ruiz H, Ríos-Moreno MJ, González-Cámpora R, Ortega I, Fernández A, García-Escudero A et al (2012) The cadherin– catenin complex in laryngeal squamous cell carcinoma. Eur Arch Otorhinolaryngol 269:1183–1188
33. Gouliomous AK, Varakis J, Goumas P, Papadaki H (2010) Deferential b-catenin expression between glottis and supraglottic laryngeal carcinoma. Eur Arch Otorhinolaryngol 267:1573–1578
34. Harris SL, Levine AJ (2005) The p53 pathway: positive and negative feedback loops. Oncogene 24:2899–2908
35. Hagedorn HG, Sauer U, Schleicher ED, Nerlich AG (2001) Divergence in distribution and prognostic significance of major basement components in laryngeal carcinomas. Int J Oncol 18: 1045–1051