메뉴 건너뛰기




Volumn 11, Issue 3, 2011, Pages 236-246

Genetics of rhinosinusitis

Author keywords

ALOX5; ALOX5AP; AOAH; Aspirin intolerant asthma; Asthma; CACNA1I; CACNG6; Chronic rhinosinusitis; CYSLTR1; Endoscopic sinus surgery; Gene association study; Genetics; IL10; IL1A; IL1RN; IL22RA1; IL33; Innate immunity; KIAA1456; LAMA2; LAMB1; MMP9; MSRA; MUSK; Nasal polyposis; NAV3; NOS1; NOS1AP; PARS2; Pooling based genome wide association study; Staphylococcal superantigens; Staphylococcus aureus; TGFB1; TNFA; TNFAIP3; Toll like receptor signaling; TP73; TRIP12

Indexed keywords

ACYLOXYACYL HYDROLASE; ALPHA 1 ANTITRYPSIN; HYDROLASE; INTERLEUKIN 1ALPHA; LAMININ; LAMININ BETA 1; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

EID: 85027919193     PISSN: 15297322     EISSN: None     Source Type: Journal    
DOI: 10.1007/s11882-011-0189-4     Document Type: Review
Times cited : (55)

References (50)
  • 1
    • 63249088853 scopus 로고    scopus 로고
    • The health and resource utilization of Canadians with chronic rhinosinusitis
    • This is a concise documentation of the health care costs of CRS
    • Macdonald, K.I., J.D. McNally, and E. Massoud, The health and resource utilization of Canadians with chronic rhinosinusitis. Laryngoscope, 2009. 119(1):184-9. This is a concise documentation of the health care costs of CRS.
    • (2009) Laryngoscope , vol.119 , Issue.1 , pp. 184-189
    • Macdonald, K.I.1    McNally, J.D.2    Massoud, E.3
  • 2
    • 34447542269 scopus 로고    scopus 로고
    • European position paper on rhinosinusitis and nasal polyps
    • Fokkens W, Lund V, Mullol J. European position paper on rhinosinusitis and nasal polyps. Rhinol Suppl. 2007;20:1-136.
    • (2007) Rhinol Suppl , vol.20 , pp. 1-136
    • Fokkens, W.1    Lund, V.2    Mullol, J.3
  • 3
    • 77950015953 scopus 로고    scopus 로고
    • Molecular characterization of the polymicrobial flora in chronic rhinosinusitis
    • Stephenson, M.F., et al., Molecular characterization of the polymicrobial flora in chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 39(2):182-7.
    • J Otolaryngol Head Neck Surg , vol.39 , Issue.2 , pp. 182-187
    • Stephenson, M.F.1
  • 4
    • 34248673434 scopus 로고    scopus 로고
    • Bacteriology of the sinus cavities of asymptomatic individuals after endoscopic sinus surgery
    • DOI 10.2310/7070.2006.0019
    • Al-Shemari H et al. Bacteriology of the sinus cavities of asymptomatic individuals after endoscopic sinus surgery. J Otolaryngol. 2007;36(1):43-8. (Pubitemid 46774561)
    • (2007) Journal of Otolaryngology , vol.36 , Issue.1 , pp. 43-48
    • Al-Shemari, H.1    Abou-Hamad, W.2    Libman, M.3    Desrosiers, M.4
  • 5
    • 38049129665 scopus 로고    scopus 로고
    • Role of staphylococcal superantigens in upper airway disease
    • This is a comprehensive review of the evidence and mechanisms for staphylococcal enterotoxins in the pathogenesis of CRS
    • Bachert, C., et al., Role of staphylococcal superantigens in upper airway disease. Curr Opin Allergy Clin Immunol, 2008. 8(1):34-8. This is a comprehensive review of the evidence and mechanisms for staphylococcal enterotoxins in the pathogenesis of CRS.
    • (2008) Curr Opin Allergy Clin Immunol , vol.8 , Issue.1 , pp. 34-38
    • Bachert, C.1
  • 6
    • 70350417294 scopus 로고    scopus 로고
    • Are biofilms the answer in the pathophysiology and treatment of chronic rhinosinusitis?
    • This is a review of bacterial biofilms, their role in CRS, and potential treatment avenues
    • Kilty, S.J. and M.Y. Desrosiers, Are biofilms the answer in the pathophysiology and treatment of chronic rhinosinusitis? Immunol Allergy Clin North Am, 2009. 29(4):645-56. This is a review of bacterial biofilms, their role in CRS, and potential treatment avenues.
    • (2009) Immunol Allergy Clin North Am , vol.29 , Issue.4 , pp. 645-656
    • Kilty, S.J.1    Desrosiers, M.Y.2
  • 7
    • 70449719323 scopus 로고    scopus 로고
    • Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization
    • This is one of several articles demonstrating the intracellular presence of bacteria in CRS
    • Corriveau, M.N., et al., Detection of Staphylococcus aureus in nasal tissue with peptide nucleic acid-fluorescence in situ hybridization. Am J Rhinol Allergy, 2009. 23(5):461-5. This is one of several articles demonstrating the intracellular presence of bacteria in CRS.
    • (2009) Am J Rhinol Allergy , vol.23 , Issue.5 , pp. 461-465
    • Corriveau, M.N.1
  • 8
    • 69349097543 scopus 로고    scopus 로고
    • Unmet needs in severe chronic upper airway disease (SCUAD)
    • This article identifies research priorities in rhinitis and sinusitis
    • Bousquet, J., et al., Unmet needs in severe chronic upper airway disease (SCUAD). J Allergy Clin Immunol, 2009. 124 (3):428-33. This article identifies research priorities in rhinitis and sinusitis.
    • (2009) J Allergy Clin Immunol , vol.124 , Issue.3 , pp. 428-433
    • Bousquet, J.1
  • 12
    • 33645278974 scopus 로고    scopus 로고
    • Familial aggregation of sinonasal polyps correlates with severity of disease
    • Cohen NA et al. Familial aggregation of sinonasal polyps correlates with severity of disease. Otolaryngol Head Neck Surg. 2006;134(4):601-4.
    • (2006) Otolaryngol Head Neck Surg , vol.134 , Issue.4 , pp. 601-604
    • Cohen, N.A.1
  • 14
    • 43749105558 scopus 로고    scopus 로고
    • Linkage disequilibrium-understanding the evolutionary past and mapping the medical future. Nature reviews
    • This is a summary of linkage disequilibrium techniques for the nonspecialist
    • Slatkin, M., Linkage disequilibrium-understanding the evolutionary past and mapping the medical future. Nature reviews. Genetics, 2008. 9(6):477-85. This is a summary of linkage disequilibrium techniques for the nonspecialist.
    • (2008) Genetics , vol.9 , Issue.6 , pp. 477-485
    • Slatkin, M.1
  • 15
    • 77952495935 scopus 로고    scopus 로고
    • Genetics of chronic rhinosinusitis: A primer
    • Tewfik, M.A., et al., Genetics of chronic rhinosinusitis: a primer. J Otolaryngol Head Neck Surg. 39(1):62-8.
    • J Otolaryngol Head Neck Surg , vol.39 , Issue.1 , pp. 62-68
    • Tewfik, M.A.1
  • 18
    • 61449255938 scopus 로고    scopus 로고
    • STrengthening the REporting of Genetic Association Studies (STREGA): An extension of the STROBE statement
    • These are widely diffused guidelines for designing, interpreting, and reporting genetic association studies
    • Little, J., et al., STrengthening the REporting of Genetic Association Studies (STREGA): an extension of the STROBE statement. PLoS Medicine, 2009. 6(2):e22. These are widely diffused guidelines for designing, interpreting, and reporting genetic association studies.
    • (2009) PLoS Medicine , vol.6 , Issue.2
    • Little, J.1
  • 19
    • 77950689572 scopus 로고    scopus 로고
    • Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis
    • This illustrates the use of genetic association studies to identify host factors conferring susceptibility to an infectious agent
    • Moller, M. and E.G. Hoal, Current findings, challenges and novel approaches in human genetic susceptibility to tuberculosis. Tuberculosis, 2010. 90(2):71-83. This illustrates the use of genetic association studies to identify host factors conferring susceptibility to an infectious agent.
    • (2010) Tuberculosis , vol.90 , Issue.2 , pp. 71-83
    • Moller, M.1    Hoal, E.G.2
  • 20
    • 33750432176 scopus 로고    scopus 로고
    • Rhinosinusitis: Developing guidance for clinical trials
    • Meltzer EO et al. Rhinosinusitis: developing guidance for clinical trials. J Allergy Clin Immunol. 2006;118(5 Suppl):S17-61.
    • (2006) J Allergy Clin Immunol , vol.118 , Issue.5 SUPPL.
    • Meltzer, E.O.1
  • 21
    • 78650404224 scopus 로고    scopus 로고
    • Modifier genes in Mendelian disorders: The example of cystic fibrosis
    • The author describes gene- gene interactions on the phenotypic impact of the genetic variation, using a disease - cystic fibrosis - with a simple mendelian model
    • Cutting, G.R., Modifier genes in Mendelian disorders: the example of cystic fibrosis. Annals of the New York Academy of Sciences, 2010. 1214: p. 57-69. The author describes gene- gene interactions on the phenotypic impact of the genetic variation, using a disease - cystic fibrosis - with a simple mendelian model.
    • (2010) Annals of the New York Academy of Sciences , vol.1214 , pp. 57-69
    • Cutting, G.R.1
  • 22
    • 77957947562 scopus 로고    scopus 로고
    • Hundreds of variants clustered in genomic loci and biological pathways affect human height
    • Lango Allen, H., et al., Hundreds of variants clustered in genomic loci and biological pathways affect human height. Nature. 467 (7317):832-8.
    • Nature , vol.467 , Issue.7317 , pp. 832-838
    • Lango Allen, H.1
  • 23
    • 79955482101 scopus 로고    scopus 로고
    • Genomewide association studies of hypertension: Light at the end of the tunnel
    • This current review identifies potential pitfalls in genetic association studies while offering concrete evidence of existing benefits from these approaches
    • Hastie, C.E., S. Padmanabhan, and A.F. Dominiczak, Genomewide association studies of hypertension: light at the end of the tunnel. Int J Hypertens. 2010:509581. This current review identifies potential pitfalls in genetic association studies while offering concrete evidence of existing benefits from these approaches.
    • (2010) Int J Hypertens , pp. 509581
    • Hastie, C.E.1    Padmanabhan, S.2    Dominiczak, A.F.3
  • 25
    • 50549083074 scopus 로고    scopus 로고
    • Curses - Winner's and otherwise - In genetic epidemiology
    • discussion 657-8
    • Kraft P. Curses - winner's and otherwise - in genetic epidemiology. Epidemiology. 2008;19(5):649-51. discussion 657-8.
    • (2008) Epidemiology , vol.19 , Issue.5 , pp. 649-651
    • Kraft, P.1
  • 27
    • 34447517267 scopus 로고    scopus 로고
    • Proinflammatory cytokine single nucleotide polymorphisms in nasal polyposis
    • Erbek, S.S., et al., Proinflammatory cytokine single nucleotide polymorphisms in nasal polyposis. Archives of otolaryngology- head & neck surgery, 2007. 133(7):705-9.
    • (2007) Archives of Otolaryngology- Head & Neck Surgery , vol.133 , Issue.7 , pp. 705-709
    • Erbek, S.S.1
  • 28
    • 77149143887 scopus 로고    scopus 로고
    • Association of IL1A, IL1B, and TNF gene polymorphisms with chronic rhinosinusitis with and without nasal polyposis: A replication study
    • Mfuna Endam, L., et al., Association of IL1A, IL1B, and TNF gene polymorphisms with chronic rhinosinusitis with and without nasal polyposis: a replication study. Arch Otolaryngol Head Neck Surg. 136(2):187-92.
    • Arch Otolaryngol Head Neck Surg , vol.136 , Issue.2 , pp. 187-192
    • Mfuna Endam, L.1
  • 29
    • 79851502150 scopus 로고    scopus 로고
    • Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology
    • Rossin, E.J., et al., Proteins encoded in genomic regions associated with immune-mediated disease physically interact and suggest underlying biology. PLoS Genet. 7(1):e1001273.
    • PLoS Genet , vol.7 , Issue.1
    • Rossin, E.J.1
  • 30
    • 63249104730 scopus 로고    scopus 로고
    • Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans
    • This is the only published "hypothesis-free" study of genetic associations in CRS; using a modification of the GWAS technique, it identifies potential candidate genes and novel pathways
    • Bosse, Y., et al., Identification of susceptibility genes for complex diseases using pooling-based genome-wide association scans. Hum Genet, 2009. 125(3):305-18. This is the only published "hypothesis-free" study of genetic associations in CRS; using a modification of the GWAS technique, it identifies potential candidate genes and novel pathways.
    • (2009) Hum Genet , vol.125 , Issue.3 , pp. 305-318
    • Bosse, Y.1
  • 31
    • 79955889652 scopus 로고    scopus 로고
    • Demonstration of a common genetic basis to CRS in Chinese and Caucasian populations
    • This is an exploration of reported differences in CRS pathophysiology between Chinese and Caucasian populations
    • Zhang, Y., et al., Demonstration of a common genetic basis to CRS in Chinese and Caucasian populations. J Allergy Clin Immunol, 2011. 127(2 Suppl): p. AB121. This is an exploration of reported differences in CRS pathophysiology between Chinese and Caucasian populations.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.2 SUPPL.
    • Zhang, Y.1
  • 32
    • 75749084420 scopus 로고    scopus 로고
    • Polymorphisms in the SERPINA1 (alpha-1- Antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy
    • Kilty, S.J., et al., Polymorphisms in the SERPINA1 (alpha-1- antitrypsin) gene are associated with severe chronic rhinosinusitis unresponsive to medical therapy. Am J Rhinol Allergy. 24(1):e4-9.
    • Am J Rhinol Allergy , vol.24 , Issue.1
    • Kilty, S.J.1
  • 33
    • 77949969655 scopus 로고    scopus 로고
    • A pooling-based genome-wide association study implicates the p73 gene in chronic rhinosinusitis
    • Tournas, A., et al., A pooling-based genome-wide association study implicates the p73 gene in chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 39(2):188-95.
    • J Otolaryngol Head Neck Surg , vol.39 , Issue.2 , pp. 188-195
    • Tournas, A.1
  • 34
    • 85028093690 scopus 로고    scopus 로고
    • Alpha-1-antitrypsin deficiency: A new clinical entity in CRS?
    • Desrosiers, M., et al., Alpha-1-antitrypsin deficiency: a new clinical entity in CRS? Journal of Allergy and Clinical Immunology, 2010. 125(2, Supplement 1):AB100.
    • (2010) Journal of Allergy and Clinical Immunology , vol.125 , Issue.2 SUPPL. 1
    • Desrosiers, M.1
  • 35
    • 79955887035 scopus 로고    scopus 로고
    • Bioinformatic analysis of epithelial cell gene expression in chronic rhinosinusitis identifies constitutive differences between CRSwNP and CRSsNP
    • This network analysis of gene expression profiles in primary epithelial cells from CRS patients identifies involvement of the same pathways as those predicted from gene association studies
    • Desrosiers, M., et al., Bioinformatic analysis of epithelial cell gene expression in chronic rhinosinusitis identifies constitutive differences between CRSwNP and CRSsNP. J Allergy Clin Immunol, 2011. 127(2 Suppl): p. AB269. This network analysis of gene expression profiles in primary epithelial cells from CRS patients identifies involvement of the same pathways as those predicted from gene association studies.
    • (2011) J Allergy Clin Immunol , vol.127 , Issue.2 SUPPL.
    • Desrosiers, M.1
  • 36
    • 77950425006 scopus 로고    scopus 로고
    • Genetic evidence for a role of IL33 in nasal polyposis
    • This is another elegant study combining genomic and transcriptomic methods. Different gene expression results in CRS identify IL33 as a candidate gene in CRS for genetic association studies
    • Buysschaert, I.D., et al., Genetic evidence for a role of IL33 in nasal polyposis. Allergy, 2010. 65(5):616-22. This is another elegant study combining genomic and transcriptomic methods. Different gene expression results in CRS identify IL33 as a candidate gene in CRS for genetic association studies.
    • (2010) Allergy , vol.65 , Issue.5 , pp. 616-622
    • Buysschaert, I.D.1
  • 37
    • 33645222918 scopus 로고    scopus 로고
    • Increased prevalence of interleukin-1 receptor antagonist gene polymorphism in patients with chronic rhinosinusitis
    • Cheng, Y.K., et al., Increased prevalence of interleukin-1 receptor antagonist gene polymorphism in patients with chronic rhinosinusitis. Archives of otolaryngology-head & neck surgery, 2006. 132(3):285-90.
    • (2006) Archives of Otolaryngology-head & Neck Surgery , vol.132 , Issue.3 , pp. 285-290
    • Cheng, Y.K.1
  • 38
    • 77956870655 scopus 로고    scopus 로고
    • Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population
    • Lee JS et al. Association of CACNG6 polymorphisms with aspirin-intolerance asthmatics in a Korean population. BMC Med Genet. 2010;11:138.
    • (2010) BMC Med Genet , vol.11 , pp. 138
    • Lee, J.S.1
  • 39
    • 77953204765 scopus 로고    scopus 로고
    • Matrix metalloproteinase-9 gene polymorphisms in nasal polyposis
    • Wang LF et al. Matrix metalloproteinase-9 gene polymorphisms in nasal polyposis. BMC Med Genet. 2010;11:85.
    • (2010) BMC Med Genet , vol.11 , pp. 85
    • Wang, L.F.1
  • 41
    • 67650287069 scopus 로고    scopus 로고
    • Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis
    • Kim SH et al. Combined effect of IL-10 and TGF-beta1 promoter polymorphisms as a risk factor for aspirin-intolerant asthma and rhinosinusitis. Allergy. 2009;64(8):1221-5.
    • (2009) Allergy , vol.64 , Issue.8 , pp. 1221-1225
    • Kim, S.H.1
  • 42
    • 67949121728 scopus 로고    scopus 로고
    • Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis
    • Bernstein JM et al. Genetic polymorphisms in chronic hyperplastic sinusitis with nasal polyposis. Laryngoscope. 2009;119 (7):1258-64.
    • (2009) Laryngoscope , vol.119 , Issue.7 , pp. 1258-1264
    • Bernstein, J.M.1
  • 43
    • 33846653174 scopus 로고    scopus 로고
    • Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients
    • Kim SH et al. Association between a TGFbeta1 promoter polymorphism and rhinosinusitis in aspirin-intolerant asthmatic patients. Respir Med. 2007;101(3):490-5.
    • (2007) Respir Med , vol.101 , Issue.3 , pp. 490-495
    • Kim, S.H.1
  • 44
    • 64549103051 scopus 로고    scopus 로고
    • Polymorphisms in the tumour necrosis factor alpha-induced protein 3 (TNFAIP3) gene are associated with chronic rhinosinusitis
    • Cormier C et al. Polymorphisms in the tumour necrosis factor alpha-induced protein 3 (TNFAIP3) gene are associated with chronic rhinosinusitis. J Otolaryngol Head Neck Surg. 2009;38 (1):133-41.
    • (2009) J Otolaryngol Head Neck Surg , vol.38 , Issue.1 , pp. 133-141
    • Cormier, C.1
  • 46
    • 77951900931 scopus 로고    scopus 로고
    • c-MET pathway involvement in chronic rhinosinusitis: A genetic association analysis
    • Castano, R., et al., c-MET pathway involvement in chronic rhinosinusitis: a genetic association analysis. Otolaryngol Head Neck Surg. 142(5):665-71 e1-2.
    • Otolaryngol Head Neck Surg , vol.142 , Issue.5
    • Castano, R.1
  • 47
    • 63849147151 scopus 로고    scopus 로고
    • Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE
    • Tewfik MA et al. Polymorphisms in interleukin-1 receptor-associated kinase 4 are associated with total serum IgE. Allergy. 2009;64(5):746-53.
    • (2009) Allergy , vol.64 , Issue.5 , pp. 746-753
    • Tewfik, M.A.1
  • 48
    • 70349257814 scopus 로고    scopus 로고
    • Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis
    • Castano, R., et al., Evidence of association of interleukin-1 receptor-like 1 gene polymorphisms with chronic rhinosinusitis. Am J Rhinol Allergy, 2009.
    • (2009) Am J Rhinol Allergy
    • Castano, R.1
  • 49
    • 79953247858 scopus 로고    scopus 로고
    • Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis
    • Zhang, Y., et al., Polymorphisms in the nitric oxide synthase 1 gene are associated with severe chronic rhinosinusitis. Am J Rhinol Allergy. 2011;25(2):e49-54.
    • (2011) Am J Rhinol Allergy , vol.25 , Issue.2
    • Zhang, Y.1
  • 50
    • 42049084864 scopus 로고    scopus 로고
    • Influence of leukotriene gene polymorphisms on chronic rhinosinusitis
    • Al-Shemari H et al. Influence of leukotriene gene polymorphisms on chronic rhinosinusitis. BMC Med Genet. 2008;9:21.
    • (2008) BMC Med Genet , vol.9 , pp. 21
    • Al-Shemari, H.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.