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Volumn 18, Issue 14, 2017, Pages 1433-1438

Ipragliflozin, a sodium glucose co-transporter 2 inhibitor, reduces intrahepatic lipid content and abdominal visceral fat volume in patients with type 2 diabetes

Author keywords

appendicular skeletal mass index; fat index; intrahepatic lipid content; intrahepatic visceral fat volume; Ipragliflozin; subcutaneous fat volume; type 2 diabetes

Indexed keywords

GLUCOSE; HEMOGLOBIN A1C; INSULIN; IPRAGLIFLOZIN; LIPID; GLUCOSIDE; SODIUM GLUCOSE COTRANSPORTER 2; THIOPHENE DERIVATIVE;

EID: 85027337209     PISSN: 14656566     EISSN: 17447666     Source Type: Journal    
DOI: 10.1080/14656566.2017.1363888     Document Type: Article
Times cited : (52)

References (23)
  • 1
    • 33845886915 scopus 로고    scopus 로고
    • Abdominal obesity and metabolic syndrome
    • Després JP, Lemieux I., Abdominal obesity and metabolic syndrome. Nature. 2006;444:881–887.
    • (2006) Nature , vol.444 , pp. 881-887
    • Després, J.P.1    Lemieux, I.2
  • 2
    • 84902672359 scopus 로고    scopus 로고
    • Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome
    • Yki-Järvinen H., Non-alcoholic fatty liver disease as a cause and a consequence of metabolic syndrome. Lancet Diabetes Endocrinol. 2014;2:901–910.
    • (2014) Lancet Diabetes Endocrinol , vol.2 , pp. 901-910
    • Yki-Järvinen, H.1
  • 3
    • 84878562914 scopus 로고    scopus 로고
    • Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review
    • Maggard-Gibbons M, Maglione M, Livhits M, et al. Bariatric surgery for weight loss and glycemic control in nonmorbidly obese adults with diabetes: a systematic review. JAMA. 2013;309:2250–2261.
    • (2013) JAMA , vol.309 , pp. 2250-2261
    • Maggard-Gibbons, M.1    Maglione, M.2    Livhits, M.3
  • 4
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, Cardiovascular Outcomes, and mortality in Type 2 diabetes
    • Zinman B, Wanner C, Lachin JM, et al. Empagliflozin, Cardiovascular Outcomes, and mortality in Type 2 diabetes. N Engl J Med. 2015;373:2117–2128.
    • (2015) N Engl J Med , vol.373 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 5
    • 85023777061 scopus 로고    scopus 로고
    • Canagliflozin and cardiovascular and renal events in Type 2 diabetes
    • [Epub], et al
    • Neal B, Perkovic V, Mahaffey KW, et al. Canagliflozin and cardiovascular and renal events in Type 2 diabetes. N Engl J Med. 2017;NEJMoa1611925. [Epub].
    • (2017) N Engl J Med , pp. 1611925
    • Neal, B.1    Perkovic, V.2    Mahaffey, K.W.3
  • 6
    • 84892479365 scopus 로고    scopus 로고
    • Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin
    • Bolinder J, Ljunggren Ö, Johansson L, et al. Dapagliflozin maintains glycaemic control while reducing weight and body fat mass over 2 years in patients with type 2 diabetes mellitus inadequately controlled on metformin. Diabetes Obes Metab. 2014;16:159–169.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 159-169
    • Bolinder, J.1    Ljunggren, Ö.2    Johansson, L.3
  • 7
    • 85016590472 scopus 로고    scopus 로고
    • Amelioration of fatty liver index in patients with type 2 diabetes on ipragliflozin: an association with glucose-lowering effects
    • Takase T, Nakamura A, Miyoshi H, et al. Amelioration of fatty liver index in patients with type 2 diabetes on ipragliflozin: an association with glucose-lowering effects. Endocr J. 2017;64:363–367.
    • (2017) Endocr J , vol.64 , pp. 363-367
    • Takase, T.1    Nakamura, A.2    Miyoshi, H.3
  • 8
    • 84858020943 scopus 로고    scopus 로고
    • Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin
    • Bolinder J, Ljunggren Ö, Kullberg J, et al. Effects of dapagliflozin on body weight, total fat mass, and regional adipose tissue distribution in patients with type 2 diabetes mellitus with inadequate glycemic control on metformin. J Clin Endocrinol Metab. 2012;97:1020–1031.
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1020-1031
    • Bolinder, J.1    Ljunggren, Ö.2    Kullberg, J.3
  • 9
    • 84979220732 scopus 로고    scopus 로고
    • Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes
    • Jojima T, Tomotsune T, Iijima T, et al. Empagliflozin (an SGLT2 inhibitor), alone or in combination with linagliptin (a DPP-4 inhibitor), prevents steatohepatitis in a novel mouse model of non-alcoholic steatohepatitis and diabetes. Diabetol Metab Syndr. 2016;8:45.
    • (2016) Diabetol Metab Syndr , vol.8 , pp. 45
    • Jojima, T.1    Tomotsune, T.2    Iijima, T.3
  • 10
    • 84953791948 scopus 로고    scopus 로고
    • The selective SGLT2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice
    • Honda Y, Imajo K, Kato T, et al. The selective SGLT2 inhibitor ipragliflozin has a therapeutic effect on nonalcoholic steatohepatitis in mice. PLoS One. 2016;11:e0146337.
    • (2016) PLoS One , vol.11
    • Honda, Y.1    Imajo, K.2    Kato, T.3
  • 11
    • 84961615237 scopus 로고    scopus 로고
    • Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in Type 2 diabetic patients irrespective of body weight reduction
    • Komiya C, Tsuchiya K, Shiba K, et al. Ipragliflozin improves hepatic steatosis in obese mice and liver dysfunction in Type 2 diabetic patients irrespective of body weight reduction. PLoS One. 2016;11:e0151511.
    • (2016) PLoS One , vol.11
    • Komiya, C.1    Tsuchiya, K.2    Shiba, K.3
  • 12
    • 84977557550 scopus 로고    scopus 로고
    • Proposed cut-off values of the waist circumference for metabolic syndrome based on visceral fat volume in a Japanese population
    • Tsukiyama H, Nagai Y, Matsubara F, et al. Proposed cut-off values of the waist circumference for metabolic syndrome based on visceral fat volume in a Japanese population. J Diabetes Investig. 2016;7:587–593.
    • (2016) J Diabetes Investig , vol.7 , pp. 587-593
    • Tsukiyama, H.1    Nagai, Y.2    Matsubara, F.3
  • 13
    • 84980324648 scopus 로고    scopus 로고
    • Proposed cut-off value of the intrahepatic lipid content for metabolically normal persons assessed by proton magnetic resonance spectroscopy in a Japanese population
    • Matsubara F, Nagai Y, Tsukiyama H, et al. Proposed cut-off value of the intrahepatic lipid content for metabolically normal persons assessed by proton magnetic resonance spectroscopy in a Japanese population. Diabetes Res Clin Pract. 2016;119:75–82.
    • (2016) Diabetes Res Clin Pract , vol.119 , pp. 75-82
    • Matsubara, F.1    Nagai, Y.2    Tsukiyama, H.3
  • 14
    • 80054883942 scopus 로고    scopus 로고
    • Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance
    • Vendrell J, El Bekay R, Peral B, et al. Study of the potential association of adipose tissue GLP-1 receptor with obesity and insulin resistance. Endocrinology. 2011;152:4072–4079.
    • (2011) Endocrinology , vol.152 , pp. 4072-4079
    • Vendrell, J.1    El Bekay, R.2    Peral, B.3
  • 15
    • 67349275999 scopus 로고    scopus 로고
    • Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus
    • Komoroski B, Vachharajani N, Feng Y, et al. Dapagliflozin, a novel, selective SGLT2 inhibitor, improved glycemic control over 2 weeks in patients with type 2 diabetes mellitus. Clin Pharmacol Ther. 2009;85:513–519.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 513-519
    • Komoroski, B.1    Vachharajani, N.2    Feng, Y.3
  • 16
    • 67349180574 scopus 로고    scopus 로고
    • Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects
    • Komoroski B, Vachharajani N, Boulton D, et al. Dapagliflozin, a novel SGLT2 inhibitor, induces dose-dependent glucosuria in healthy subjects. Clin Pharmacol Ther. 2009;85:520–526.
    • (2009) Clin Pharmacol Ther , vol.85 , pp. 520-526
    • Komoroski, B.1    Vachharajani, N.2    Boulton, D.3
  • 17
    • 65349196064 scopus 로고    scopus 로고
    • Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes
    • List JF, Woo V, Morales E, et al. Sodium-glucose cotransport inhibition with dapagliflozin in type 2 diabetes. Diabetes Care. 2009;32:650–657.
    • (2009) Diabetes Care , vol.32 , pp. 650-657
    • List, J.F.1    Woo, V.2    Morales, E.3
  • 18
    • 84886558949 scopus 로고    scopus 로고
    • Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease
    • Kawano Y, Cohen DE. Mechanisms of hepatic triglyceride accumulation in non-alcoholic fatty liver disease. J Gastroenterol. 2013;48:434–441.
    • (2013) J Gastroenterol , vol.48 , pp. 434-441
    • Kawano, Y.1    Cohen, D.E.2
  • 19
    • 84987624200 scopus 로고    scopus 로고
    • The Na+/Glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels
    • Hawley SA, Ford RJ, Smith BK, et al. The Na+/Glucose cotransporter inhibitor canagliflozin activates AMPK by inhibiting mitochondrial function and increasing cellular AMP levels. Diabetes. 2016;65:2784–2794.
    • (2016) Diabetes , vol.65 , pp. 2784-2794
    • Hawley, S.A.1    Ford, R.J.2    Smith, B.K.3
  • 20
    • 79954993397 scopus 로고    scopus 로고
    • Intrahepatic lipid content is linked to insulin resistance in obese subjects
    • Sada Y, Katabami T, Asai S, et al. Intrahepatic lipid content is linked to insulin resistance in obese subjects. Obes Res Clin Pract. 2011;5:e79–e156.
    • (2011) Obes Res Clin Pract , vol.5 , pp. e79-e156
    • Sada, Y.1    Katabami, T.2    Asai, S.3
  • 21
    • 85011824697 scopus 로고    scopus 로고
    • Measurement of muscle mass in sarcopenia: from imaging to biochemical markers
    • Tosato M, Marzetti E, Cesari M, et al. Measurement of muscle mass in sarcopenia: from imaging to biochemical markers. Aging Clin Exp Res. 2017;29:19–27.
    • (2017) Aging Clin Exp Res , vol.29 , pp. 19-27
    • Tosato, M.1    Marzetti, E.2    Cesari, M.3
  • 22
    • 84896405128 scopus 로고    scopus 로고
    • Assessing skeletal muscle mass: historical overview and state of the art
    • Heymsfield SB, Adamek M, Gonzalez MC, et al. Assessing skeletal muscle mass: historical overview and state of the art. J Cachexia Sarcopenia Muscle. 2014;5:9–18.
    • (2014) J Cachexia Sarcopenia Muscle , vol.5 , pp. 9-18
    • Heymsfield, S.B.1    Adamek, M.2    Gonzalez, M.C.3
  • 23
    • 84951906012 scopus 로고    scopus 로고
    • Energy balance after sodium-glucose cotransporter 2 inhibition
    • Ferrannini G, Hach T, Crowe S, et al. Energy balance after sodium-glucose cotransporter 2 inhibition. Diabetes Care. 2015;38:1730–1735.
    • (2015) Diabetes Care , vol.38 , pp. 1730-1735
    • Ferrannini, G.1    Hach, T.2    Crowe, S.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.