Sexual orientation and suicidal behaviour in adolescents and young adults: Systematic review and meta-analysis

British Journal of Psychiatry

Volumn 211, Issue 2, 2017, Pages 77-87

  Miranda Mendizabal A ^a   Castellvi P ^b   Pares Badell O ^b   Almenara, J ^c   Alonso, I ^d   Blasco, M J ^b   Cebria A ^e   Gabilondo, A ^f   Gili, M ^g   Lagares, C ^c   Piqueras, J A ^h   Roca, M ^g   Rodriguez Marin J ^h   Rodriguez Jimenez T ^h   Soto Sanz, V ^h   Vilagut, G ^b   Alonso, J ^b  

^a UNIVERSITAT POMPEU FABRA   (Spain)

^b INST MUNIC D INVESTIGACIO MEDICA   (Spain)

^c UNIVERSITY OF CÁDIZ   (Spain)

^d HOSPITAL MORALES MESEGUER   (Spain)

^e Corporació Sanitaria Pare Taulí ^*  (Spain)

^f BIODONOSTIA HEALTH RESEARCH INSTITUTE   (Spain)

^g UNIVERSITAT DE LES ILLES BALEARS   (Spain)

^h MIGUEL HERNÁNDEZ UNIVERSITY   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ATTRIBUTABLE RISK; AUTOMUTILATION; BISEXUAL FEMALE; BISEXUAL MALE; DEPRESSION; HETEROSEXUAL FEMALE; HETEROSEXUAL MALE; HOMOSEXUAL FEMALE; HOMOSEXUAL MALE; HUMAN; LONGITUDINAL STUDY; META ANALYSIS; POPULATION RESEARCH; REVIEW; RISK FACTOR; SEXUAL ORIENTATION; SUICIDAL BEHAVIOR; SUICIDE ATTEMPT; SYSTEMATIC REVIEW; YOUNG ADULT; PSYCHOLOGY; SEXUAL AND GENDER MINORITY; SEXUAL BEHAVIOR; SUICIDAL IDEATION;

RISK FACTORS; SEXUAL AND GENDER MINORITIES; SEXUAL BEHAVIOR; SUICIDAL IDEATION; SUICIDE, ATTEMPTED;

EID: 85026796631     PISSN: 00071250     EISSN: 14721465     Source Type: Journal    
DOI: 10.1192/bjp.bp.116.196345     Document Type: Review

References (65)

1. World Health Organization Europe. Mental Health: Facing the Challenges, Building Solutions. WHO, 2005.
2. World Health Organization. Preventing Suicide, A Global Imperative. WHO, 2014.
3. Borges G, Angst J, Nock MK, Ruscio AM, Kessler RC. Risk factors for the incidence and persistence of suicide-related outcomes: a 10-year follow-up study using the National Comorbidity Surveys. J Affect Disord 2008; 105: 25-33.
4. Kessler R, Berglund P, Borges G. Trends in suicide ideation, plans, gestures, and attempts in the United States, 1990-1992 to 2001-2003. JAMA 2005; 293: 1990-2.
5. Brent D, Mann J. Family genetic studies, suicide, and suicidal behavior. Am J Med Genet C Semin Med Genet 2005; 133C: 13-24.
6. Remafedi G, French S. The relationship between suicide risk and sexual orientation: results of a population-based study. Am J Public Health 1998; 88: 57-61.
7. Haas AP, Eliason M, Mays VM, Mathy RM, Cochran SD, D'Augelli AR, et al. Suicide and suicide risk in lesbian, gay, bisexual, and transgender populations: review and recommendations. J Homosex 2011; 58: 10-51.
8. McLaughlin KA, Hatzenbuehler ML, Keyes KM. Responses to discrimination and psychiatric disorders among Black, Hispanic, female, and lesbian, gay, and bisexual individuals. Am J Public Health 2010; 100: 1477-84.
9. Diaz R, Ayala G, Bein E, Henne J, Marin B. The impact of homophobia, poverty, and racism on the mental health of gay and bisexual Latino men: findings from 3 US cities. Am J Public Health 2001; 91: 927-32.
10. Coker TR, Austin SB, Schuster MA. The health and health care of lesbian, gay, and bisexual adolescents. Annu Rev Public Health 2010; 31: 457-77.
11. Meyer I. Prejudice, social stress, and mental health in lesbian, gay, and bisexual populations: conceptual issues and research evidence. Psychol Bull 2003; 129: 674-97.
12. Marshal M, Dietz L, Friedman M. Suicidality and depression disparities between sexual minority and heterosexual youth: a meta-analytic review. J Adolesc Health 2011; 49: 115-23.
13. World Health Organization. Health for the worlds Adolescents. A second Chance in the Second Decade, WHO, 2014.
14. Garg AX, Hackam D, Tonelli M. Systematic review and meta-analysis: when one study is just not enough. Clin J Am Soc Nephrol 2008; 3: 253-60.
15. Tooth L, Ware R, Bain C, Purdie DM, Dobson A. Quality of reporting of observational longitudinal research. Am J Epidemiol 2005; 161: 280-8.
16. Alonso J, Castellvi P. Pares O, Gabilondo A, cebria Al, Rodriguez Marin J, et al. Predictive factors of suicidal behavior and suicide in adolescents and young people: a systematic review. CRD42013005775 (http://www.crd.york.ac.uk/ PROSPERO).
17. stroup D, Berlin J, Morton S. Meta-analysis of observational studies in epidemiology: a proposal for reporting. JAMA 2000; 283: 2008-12.
18. Silverman M, Berman A. Rebuilding the tower of Babel: a revised nomenclature for the study of suicide and suicidal behaviors. Part 2: Suicide-related ideations, communications, and behaviors. Suicide Life Threat Behav 2007; 37: 264-77.
19. Money J. The concept of gender identity disorder in childhood and adolescence after 39 years. J Sex Marital Ther 1994; 20: 163-77.
20. World Health Organization. The ICD-10 Classification of Mental and Behavioural Disorders, WHO, 1992.
21. Wells GA, Shea B, O'Connell D, Peterson J, Welch V, Losos M. The Newcastle-Ottawa Scale (NOS) for assessing the quality of nonrandomised studies in meta-analyses. Ottawa Hospital Research institute, 2014 (http://www.ohri.ca/ programs/clinicaLepidemiology/oxford.asp).
22. Fergusson DM, Horwood U, Beautrais AL. IS sexual orientation related to mental health problems and suicidality in young people? Arch Gen Psychiatry 1999; 56: 876-80.
23. Skegg K, Nada-Raja S, Dickson N, Paul C, Williams S. sexual orientation and self-harm in men and women. Am J Psychiatry 2003; 160: 541-6.
24. Wichstrom L, Hegna K. Sexual orientation and suicide attempt: a longitudinal study of the general Norwegian adolescent population. J Abnorm Psychol 2003; 112: 144-51.
25. Silenzio VMB, Pena JB, Duberstein PR, Cerel J, Knox KL sexual orientation and risk factors for suicidal ideation and suicide attempts among adolescents and young adults. Am J Public Health 2007; 97: 2017-9.
26. Young R, Riordan V, stark C Perinatal and psychosocial circumstances associated with risk of attempted suicide, non-suicidal self-injury and psychiatric service use. A longitudinal study of young people. BMC Public Health 2011; 11: 875.
27. Whitlock J, Muehlenkamp J, Eckenrode J, Purington A, Baral Abrams G, Barreira P, et al. Nonsuicidal self-injury as a gateway to suicide in young adults. J Adolesc Health 2013; 52: 486-92.
28. Zhang J, Yu KF. What's the relative risk? A method of correcting the odds ratio in cohort studies of common outcomes. JAMA 1998; 280: 1690-1.
29. Higgins JPT, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med 2002; 21: 1539-58.
30. Harbord RM, Egger M, Sterne JAC. A modified test for small-study effects in meta-analyses of controlled trials with binary endpoints. Star Med 2006; 25: 3443-57.
31. Fergusson DM, Horwood U, Ridder EM, Beautrais AL. sexual orientation and mental health in a birth cohort of young adults. Psychol Med 2005; 35: 971-81.
32. Bearman PS, Moody J. Suicide and friendships among American adolescents. Am J Public Health 2004; 94: 89-95.
33. Noell JW, Ochs LM. Relationship of sexual orientation to substance use, suicidal ideation, suicide attempts, and other factors in a population of homeless adolescents. J Adolesc Health 2001; 29: 31-6.
34. Shaffer D, Fisher P, Parides M, Gould M. sexual orientation in adolescents who commit suicide. Suicide Life Threat Behav 1995; 25: 64-71.
35. Fried LE, Williams S, Cabral H, Hacker K. Differences in risk factors for suicide attempts among 9th and 11th grade youth: a longitudinal perspective. J Sch Nurs 2012; 29: 113-22.
36. D'Augelli AR, Grossman AH, Salter NP, vasey JJ, Starks MT, Sinclair KO. Predicting the suicide attempts of lesbian, gay, and bisexual youth. Suicide Life Threat Behav 2005; 35: 646-60.
37. Mustanski B, Liu RT. A longitudinal study of predictors of suicide attempts among lesbian, gay, bisexual, and transgender youth. Arch Sex Behav 2013; 42: 437-48.
38. Burns MN, Ryan DT, Garofalo R, Newcomb ME, Mustanski B. Mental health disorders in young urban sexual minority men. J Adolesc Health 2015; 56: 52-8.
39. Lohonen J, Isohanni M, Nieminen P, Miettunen J. Coverage of the bibliographic databases in mental health research. Nord J Psychiatry 2010; 64: 181-8.
40. Devries KM, Mak JY, Bacchus U, Child JC, Falder G, Petzold M, et al. intimate partner violence and incident depressive symptoms and suicide attempts: a systematic review of longitudinal studies. PLoS Med 2013; 10: ei00i439.
41. Buller AM, Devries KM, Howard LM, Bacchus U. Associations between intimate partner violence and health among men who have sex with men: a systematic review and meta-analysis. PLoS Med 2014; 11: ei00i609.
42. Maxwell L, Devries K, Zionts D, Alhusen JL, Campbell J. Estimating the effect of intimate partner violence on women's use of contraception: a systematic review and meta-analysis. PLoS One 2015; 10: e0118234.
43. Holler JG, Bech CN, Henriksen DP, Mikkelsen D, Pedersen C, Lassen AT. Nontraumatic hypotension and shock in the emergency department and the prehospital setting, prevalence, etiology, and mortality: a systematic review. PLoS One 2015; 10: e0119331.
44. Daglas R, Yucel M, Cotton S, Allott K, Hetrick S. Berk M. Cognitive impairment in first-episode mania: a systematic review of the evidence in the acute and remission phases of the illness, Int J Bipolar Disord 2015; 3: 9.
45. Oremus C, Oremus M, McNeely H, Losier B, Parlar M, King M, et al. Effects of electroconvulsive therapy on cognitive functioning in patients with depression: protocol for a systematic review and meta-analysis. BMJ 2015; 5: e006966.
46. Overdevest GM, Jacobs W, vieggeert-Lankamp C, Thome C, Gunzburg R, Peul W. Effectiveness of posterior decompression techniques compared with conventional laminectomy for lumbar stenosis. Cochrane Database Syst Rev 2015; 3: CD010036.
47. King M, Semlyen J, Tai SS, Killaspy H, Osborn D, Popelyuk D, et al. A systematic review of mental disorder, suicide, and deliberate self harm in lesbian, gay and bisexual people. BMC Psychiatry 2008; 8: 70.
48. Garofalo R, Wolf RC, Wissow LS, woods ER, Goodman E. Sexual orientation and risk of suicide attempts among a representative sample of youth. Arch Pediatr Adolesc Med 1999; 153: 487-93.
49. Botnick MR, Heath KV, cornelisse PG, Strathdee SA, Martindale SL, Hogg RS. Correlates of suicide attempts in an open cohort of young men who have sex with men. Can J Public Health 2002; 93: 59-62.
50. Paul JP, Catania J, Pollack L, Moskowitz J, Canchola J, Mills T, et al. Suicide attempts among gay and bisexual men: lifetime prevalence and antecedents. Am J Public Health 2002; 92: 1338-45.
51. Remafedi G. Suicidality in a venue-based sample of young men who have sex with men. J Adolesc Health 2002; 31: 305-10.
52. Russell ST, Toomey RB. Men's sexual orientation and suicide: evidence for U.S. adolescent-specific risk, Soc Sci Med 2012; 74: 523-9.
53. Jackson S. Gender, sexuality and heterosexuality: the complexity (and limits) of heteronormativity. Fern Theory 2006; 7: 105-21.
54. Harter S. Self and identity development. In At the Threshold: The Developing Adolescent (eds S Feldman, G Elliott): 352-87. Harvard University Press, 1990.
55. Pompili M, Lester D, Forte A, seretti ME, Erbuto D, Lamis DA, et al. Bisexuality and suicide: a systematic review of the current literature. J Sex Med 2014; 11: 1903-13.
56. Machado S. The poetics of parent-son encounters following negative parental reactions to the disclosure of gay identity. J Humanist Psychol 2014; 55: 30-52.
57. Meyer IH. Minority stress and mental health in gay men. J Health Soc Behav 1995; 36: 38.
58. Meyer I, Dean L. internalized homophobia, intimacy and sexual behaviour among gay and bisexual men. In Stigma and Sexual Orientation (ed. G Herek): 160-86. Sage, 1998.
59. Hammelman T. Gay and lesbian youth, contributing factors to serious attempts or considerations of suicide. J Gay Lesbian Psychother 1993; 2: 77-89.
60. Armesto J, weisman A. Attributions and emotional reactions to the identity disclosure ('coming out') of a homosexual child. Fam Process 2001; 40: 145-61.
61. Ryan C, Huebner D, Diaz R, Sanchez J. Family rejection as a predictor of negative health outcomes in White and Latino lesbian, gay, and bisexual young adults. Pediatrics 2009; 123: 346-52.
62. Gecas V, Libby R. Sexual behavior as symbolic interaction. J Sex Res 1976; 12: 33-49.
63. American Psychological Association. The Guidelines for Psychological Practice with Lesbian, Gay and Bisexual Clients. APA, 2011.
64. O'Connor D, Green S, Higgins JPT. Defining the review question and developing criteria for including studies, in Cochrane Handbook for Systematic Reviews of Interventions (eds J Higgins, S Green): ch 5. Cochrane Collaboration, 2008.
65. Sterne J, Sutton A, Ioannidis J, Terrin N, Jones D, Lau J, et al. Recommendations for examining and interpreting funnel plot asymmetry in meta-analyses of randomised controlled trials. BMJ 2011; 342: d4002.