Occurrence of plasmid- and chromosome-carried mcr-1 in waterborne Enterobacteriaceae in China

Antimicrobial Agents and Chemotherapy

Volumn 61, Issue 8, 2017, Pages

  Zhou, Hong Wei ^a   Zhang, Ting ^a   Ma, Ji Hua ^a   Fang, Ying ^a   Wang, Han Yu ^b   Huang, Zi Xian ^c   Wang, Yang ^d   Wu, Congming ^d   Chen, Gong Xiang ^a  

^a ZHEJIANG UNIVERSITY SCHOOL OF MEDICINE   (China)

^b UNIVERSITY OF CONNECTICUT   (United States)

^c HANGZHOU NORMAL UNIVERSITY   (China)

^d CHINA AGRICULTURAL UNIVERSITY   (China)

Author keywords

Chromosome carried; Enrichment broth culture; Enterobacteriaceae; mcr 1; Plasmid carried; Polymyxin resistance

Indexed keywords

COLISTIN; WATER; ANTIINFECTIVE AGENT; BACTERIAL PROTEIN; BETA LACTAMASE; ESCHERICHIA COLI PROTEIN; MCR-1 PROTEIN, E COLI; POLYMYXIN;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CHROMOSOME; BACTERIAL GENE; BACTERIUM CULTURE; BACTERIUM ISOLATE; CHINA; CITROBACTER; CITROBACTER BRAAKII; CITROBACTER FREUNDII; CLONAL VARIATION; CONJUGATION; CONTROLLED STUDY; DNA HYBRIDIZATION; ENRICHMENT CULTURE; ENTEROBACTER CLOACAE; ENTEROBACTERIACEAE; ESCHERICHIA COLI; GENE TRANSFER; KLEBSIELLA OXYTOCA; MCR 1 GENE; MULTILOCUS SEQUENCE TYPING; NONHUMAN; OQX GENE; PLASMID; PRIORITY JOURNAL; PULSED FIELD GEL ELECTROPHORESIS; QNRS GENE; BACTERIUM IDENTIFICATION; BETA-LACTAM RESISTANCE; CLASSIFICATION; DRUG EFFECTS; GENETICS; MICROBIOLOGY;

ANTI-BACTERIAL AGENTS; BACTERIAL PROTEINS; BACTERIAL TYPING TECHNIQUES; BETA-LACTAM RESISTANCE; BETA-LACTAMASES; CHINA; CHROMOSOMES, BACTERIAL; COLISTIN; DRUG RESISTANCE, BACTERIAL; ELECTROPHORESIS, GEL, PULSED-FIELD; ENTEROBACTERIACEAE; ESCHERICHIA COLI PROTEINS; MULTILOCUS SEQUENCE TYPING; PLASMIDS; POLYMYXINS; WATER MICROBIOLOGY;

EID: 85026408629     PISSN: 00664804     EISSN: 10986596     Source Type: Journal    
DOI: 10.1128/AAC.00017-17     Document Type: Article

References (29)

1. Smith Moland E, Hanson ND, Herrera VL, Black JA, Lockhart TJ, Hossain A, Johnson JA, Goering RV, Thomson KS. 2003. Plasmid-mediated, carbapenem-hydrolysing beta-lactamase, KPC-2, in Klebsiella pneumoniae isolates. J Antimicrob Chemother 51:711–714. https://doi.org/10.1093/jac/dkg124.
2. Papagiannitsis CC, Miriagou V, Giakkoupi P, Tzouvelekis LS, Vatopoulos AC. 2013. Characterization of pKP1780, a novel IncR plasmid from the emerging Klebsiella pneumoniae ST147, encoding the VIM-1 metallo-beta-lactamase. J Antimicrob Chemother 68:2259–2262. https://doi.org/10.1093/jac/dkt196.
3. Zhang X, Li X, Wang M, Yue H, Li P, Liu Y, Cao W, Yao D, Liu L, Zhou X, Zheng R, Bo T. 2015. Outbreak of NDM-1-producing Klebsiella pneumoniae causing neonatal infection in a teaching hospital in mainland China. Antimicrob Agents Chemother 59:4349–4351. https://doi.org/10.1128/AAC.03868-14.
4. Chen LR, Zhou HW, Cai JC, Zhang R, Chen GX. 2009. Combination of IMP-4 metallo-beta-lactamase production and porin deficiency causes carbapenem resistance in a Klebsiella oxytoca clinical isolate. Diagn Microbiol Infect Dis 65:163–167. https://doi.org/10.1016/j.diagmicrobio.2009.07.002.
5. Zhang R, Yang L, Cai JC, Zhou HW, Chen GX. 2008. High-level carbapenem resistance in a Citrobacter freundii clinical isolate is due to a combination of KPC-2 production and decreased porin expression. J Med Microbiol 57:332–337. https://doi.org/10.1099/jmm.0.47576-0.
6. Hu FP, Guo Y, Zhu DM, Wang F, Jiang XF, Xu YC, Zhang XJ, Zhang CX, Ji P, Xie Y, Kang M, Wang CQ, Wang AM, Xu YH, Shen JL, Sun ZY, Chen ZJ, Ni YX, Sun JY, Chu YZ, Tian SF, Hu ZD, Li J, Yu YS, Lin J, Shan B, Du Y, Han Y, Guo S, Wei LH, Wu L, Zhang H, Kong J, Hu YJ, Ai XM, Zhuo C, Su DH, Yang Q, Jia B, Huang W. 2016. Resistance trends among clinical isolates in China reported from CHINET surveillance of bacterial resistance, 2005-2014. Clin Microbiol Infect 22 Suppl 1:S9–S14. https://doi.org/10.1016/j.cmi.2016.01.001.
7. Liu YY, Wang Y, Walsh TR, Yi LX, Zhang R, Spencer J, Doi Y, Tian G, Dong B, Huang X, Yu LF, Gu D, Ren H, Chen X, Lv L, He D, Zhou H, Liang Z, Liu JH, Shen J. 2016. Emergence of plasmid-mediated colistin resistance mechanism MCR-1 in animals and human beings in China: a microbiological and molecular biological study. Lancet Infect Dis 16:161–168. https://doi.org/10.1016/S1473-3099(15)00424-7.
8. Du H, Chen L, Tang YW, Kreiswirth BN. 2016. Emergence of the mcr-1 colistin resistance gene in carbapenem-resistant Enterobacteriaceae. Lancet Infect Dis 16:287–288. https://doi.org/10.1016/S1473-3099(16)00056-6.
9. Lee JY, Ko KS. 2014. Mutations and expression of PmrAB and PhoPQ related with colistin resistance in Pseudomonas aeruginosa clinical isolates. Diagn Microbiol Infect Dis 78:271–276. https://doi.org/10.1016/j.diagmicrobio.2013.11.027.
10. Poirel L, Kieffer N, Brink A, Coetze J, Jayol A, Nordmann P. 2016. Genetic features of MCR-1-producing colistin-resistant Escherichia coli isolates in South Africa. Antimicrob Agents Chemother 60:4394 – 4397. https://doi.org/10.1128/AAC.00444-16.
11. Elnahriry SS, Khalifa HO, Soliman AM, Ahmed AM, Hussein AM, Shimamoto T, Shimamoto T. 2016. Emergence of plasmid-mediated colistin resistance gene mcr-1 in a clinical Escherichia coli isolate from Egypt. Antimicrob Agents Chemother 60:3249–3250. https://doi.org/10.1128/AAC.00269-16.
12. Malhotra-Kumar S, Xavier BB, Das AJ, Lammens C, Hoang HT, Pham NT, Goossens H. 2016. Colistin-resistant Escherichia coli harbouring mcr-1 isolated from food animals in Hanoi, Vietnam. Lancet Infect Dis 16: 286–287. https://doi.org/10.1016/S1473-3099(16)00014-1.
13. Xavier BB, Lammens C, Ruhal R, Kumar-Singh S, Butaye P, Goossens H, Malhotra-Kumar S. 2016. Identification of a novel plasmid-mediated colistin-resistance gene, mcr-2, in Escherichia coli, Belgium, June 2016. Euro Surveill 21:.pii30280. http://www.eurosurveillance.org/ViewArticle .aspx?ArticleId22525.
14. Falgenhauer L, Waezsada SE, Yao Y, Imirzalioglu C, Kasbohrer A, Roesler U, Michael GB, Schwarz S, Werner G, Kreienbrock L, Chakraborty T, RESET consortium. 2016. Colistin resistance gene mcr-1 in extended-spectrum beta-lactamase-producing and carbapenemase-producing Gram-negative bacteria in Germany. Lancet Infect Dis 16:282–283. https://doi.org/10.1016/S1473-3099(16)00009-8.
15. Rapoport M, Faccone D, Pasteran F, Ceriana P, Albornoz E, Petroni A, MCR Group, Corso A. 2016. First description of mcr-1-mediated colistin resistance in human infections caused by Escherichia coli in Latin America. Antimicrob Agents Chemother 60:4412– 4413. https://doi.org/10.1128/AAC.00573-16.
16. Zurfuh K, Poirel L, Nordmann P, Nuesch-Inderbinen M, Hachler H, Stephan R. 2016. Occurrence of the plasmid-borne mcr-1 colistin resistance gene in extended-spectrum-beta-lactamase-producing Enterobacteriaceae in river water and imported vegetable samples in Switzerland. Antimicrob Agents Chemother 60:2594 –2595. https://doi.org/10.1128/AAC.00066-16.
17. Zhang R, Huang Y, Chan EW, Zhou H, Chen S. 2016. Dissemination of the mcr-1 colistin resistance gene. Lancet Infect Dis 16:291–292. https://doi.org/10.1016/S1473-3099(16)00062-1.
18. Zurfluh K, Tasara T, Poirel L, Nordmann P, Stephan R. 2016. Draft genome sequence of Escherichia coli S51, a chicken isolate harboring a chromo-somally encoded mcr-1 gene. Genome Announc 4:e00796-16. https://doi.org/10.1128/genomeA.00796-16.
19. Shen Z, Wang Y, Shen Y, Shen J, Wu C. 2016. Early emergence of mcr-1 in Escherichia coli from food-producing animals. Lancet Infect Dis 16:293. https://doi.org/10.1016/S1473-3099(16)00061-X.
20. Hu YY, Cai JC, Zhou HW, Chi D, Zhang XF, Chen WL, Zhang R, Chen GX. 2013. Molecular typing of CTX-M-producing Escherichia coli isolates from environmental water, swine feces, specimens from healthy humans, and human patients. Appl Environ Microbiol 79:5988 –5996. https://doi.org/10.1128/AEM.01740-13.
21. Zhang R, Ichijo T, Huang YL, Cai JC, Zhou HW, Yamaguchi N, Nasu M, Chen GX. 2012. High prevalence of qnr and aac(6=)-Ib-cr genes in both water-borne environmental bacteria and clinical isolates of Citrobacter freundii in China. Microbes Environ 27:158 –163. https://doi.org/10.1264/jsme2.ME11308.
22. QYResearch Polymyxin E Research Center. 2015. The global polymyxin industry report 2015. QYResearch, Beijing, China.
23. Li R, Xie M, Zhang J, Yang Z, Liu L, Liu X, Zheng Z, Chan EW, Chen S. 2017. Genetic characterization of mcr-1-bearing plasmids to depict molecular mechanisms underlying dissemination of the colistin resistance determinant. J Antimicrob Chemother 72:393– 401. https://doi.org/10.1093/jac/dkw411.
24. Wirth T, Falush D, Lan R, Colles F, Mensa P, Wieler LH, Karch H, Reeves PR, Maiden MC, Ochman H, Achtman M. 2006. Sex and virulence in Escherichia coli: an evolutionary perspective. Mol Microbiol 60:1136 –1151. https://doi.org/10.1111/j.1365-2958.2006.05172.x.
25. Bai L, Hurley D, Li J, Meng Q, Wang J, Fanning S, Xiong Y. 2016. Character-isation of multidrug-resistant Shiga toxin-producing Escherichia coli cultured from pigs in China: co-occurrence of extended-spectrum beta-lactamase- and mcr-1-encoding genes on plasmids. Int J Antimicrob Agents 48: 445– 448. https://doi.org/10.1016/j.ijantimicag.2016.06.021.
26. Yu Y, Ji S, Chen Y, Zhou W, Wei Z, Li L, Ma Y. 2007. Resistance of strains producing extended-spectrum beta-lactamases and genotype distribution in China. J Infect 54:53–57. https://doi.org/10.1016/j.jinf.2006.01.014.
27. Jiang Y, Zhou Z, Qian Y, Wei Z, Yu Y, Hu S, Li L. 2008. Plasmid-mediated quinolone resistance determinants qnr and aac(6=)-Ib-cr in extended-spectrum beta-lactamase-producing Escherichia coli and Klebsiella pneumoniae in China. J Antimicrob Chemother 61:1003–1006. https://doi.org/ 10.1093/jac/dkn063.
28. Ma J, Zeng Z, Chen Z, Xu X, Wang X, Deng Y, Lu D, Huang L, Zhang Y, Liu J, Wang M. 2009. High prevalence of plasmid-mediated quinolone resistance determinants qnr, aac(6=)-Ib-cr, and qepA among ceftiofur-resistant Enterobacteriaceae isolates from companion and food-producing animals. Antimicrob Agents Chemother 53:519–524. https:// doi.org/10.1128/AAC.00886-08.
29. Kim HB, Wang M, Park CH, Kim EC, Jacoby GA, Hooper DC. 2009. oqxAB encoding a multidrug efflux pump in human clinical isolates of Enterobacteriaceae. Antimicrob Agents Chemother 53:3582–3584. https://doi.org/10.1128/AAC.01574-08.