A fit-for-purpose LC–MS/MS method for the simultaneous quantitation of ATP and 2,3-DPG in human K2EDTA whole blood

Journal of Chromatography B: Analytical Technologies in the Biomedical and Life Sciences

Volumn 1061-1062, Issue , 2017, Pages 89-96

  Kim, Hyeryun ^a   Kosinski, Penelope ^a   Kung, Charles ^a   Dang, Lenny ^a   Chen, Yue ^a   Yang, Hua ^a   Chen, Yuan Shek ^b   Kramer, Jordyn ^b   Liu, Guowen ^a  

^a AGIOS PHARMACEUTICALS   (United States)

^b QPS LLC   (United States)

Author keywords

2,3 DPG; ATP; Biomarker; Blood; Endogenous compounds; Quantitative

Indexed keywords

ADENOSINETRIPHOSPHATE; BIOMARKERS; CHROMATOGRAPHY; HYDROPHILICITY; ION CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLITES;

2,3-DPG; ENDOGENOUS COMPOUND; HYDROPHILIC INTERACTION CHROMATOGRAPHY; PROTEIN PRECIPITATION EXTRACTIONS; QUANTITATIVE; STABLE ISOTOPE LABELED INTERNAL STANDARDS; TANDEM MASS SPECTROMETRY; ZWITTERIONIC ION CHROMATOGRAPHIES;

BLOOD;

2,3 DIPHOSPHOGLYCERIC ACID; ADENOSINE TRIPHOSPHATE; AMPHOLYTE; EDETIC ACID; STABLE ISOTOPE;

ACCURACY; ARTICLE; BLOOD SAMPLING; HUMAN; HYDROPHILIC INTERACTION CHROMATOGRAPHY; LIMIT OF QUANTITATION; LIQUID CHROMATOGRAPHY-MASS SPECTROMETRY; PRECIPITATION; PRIORITY JOURNAL; STANDARD; TANDEM MASS SPECTROMETRY; BLOOD; CHEMISTRY; LIMIT OF DETECTION; LIQUID CHROMATOGRAPHY; PROCEDURES; REPRODUCIBILITY; STATISTICAL MODEL;

2,3-DIPHOSPHOGLYCERATE; ADENOSINE TRIPHOSPHATE; CHROMATOGRAPHY, LIQUID; EDETIC ACID; HUMANS; LIMIT OF DETECTION; LINEAR MODELS; REPRODUCIBILITY OF RESULTS; TANDEM MASS SPECTROMETRY;

EID: 85023647260     PISSN: 15700232     EISSN: 1873376X     Source Type: Journal    
DOI: 10.1016/j.jchromb.2017.07.010     Document Type: Article

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