The dipeptidyl peptidase-4 inhibitor may improve the insulin secretion in type 2 diabetes patients just after starting hemodialysis treatment: Preliminary study

Renal Replacement Therapy

Volumn 2, Issue 1, 2016, Pages

  Kawamoto, Shinya ^a   Koda, Ryo ^a   Imanishi, Yuji ^a   Yoshino, Atsunori ^a   Takeda, Tetsuro ^a  

^a DOKKYO MEDICAL UNIVERSITY   (Japan)

Author keywords

Beta cell function; Diabetes mellitus; DPP 4 inhibitor; GLP 1; Hemodialysis

Indexed keywords

EID: 85023635012     PISSN: None     EISSN: 20591381     Source Type: Journal    
DOI: 10.1186/s41100-016-0050-2     Document Type: Article

References (19)

1. Shima K, Komatsu M, Kuwahara K, Minaguchi J, Kawashima S. Stringent glycemic control prolongs survival in diabetic patients with end-stage renal disease on hemodialysis. Nephrology. 2010;15:632-8.
2. Ricks J, Molnar MZ, Kovesdy CP, Shal A, Nissenson AR, Williams M, et al. Glycemic control and cardiovascular mortality in hemodialysis patients with diabetes: A 6-year cohort study. Diabetes. 2012;61:708-15.
3. Nakamura Y, Shimizu T, Fujita K, Inoue M, Gotoh H, Gotoh Y, et al. Effects of alogliptin benzoate in hemodialysis patients with diabetes. J Jpn Soc Dial Ther. 2012;45(1):49-57.
4. Ishioka K, Furuya R, Iwagami M, Tsutsumi D, Mochida Y, Oka M, et al. Vildagliptin improves glycemic control in type 2 diabetes patients undergoing hemodialysis. J Jpn Soc Dial Ther. 2013;46(1):103-10.
5. Gondo A, Matsumoto H, Okada T, Nagaoka Y, Yoshino M, Tomaru R, et al. A simple method of evaluationg endogenous insulin secretory function durinjg hemodialysis session. J Jpn Soc Dial Ther. 2008;41(3):187-93.
6. Cobelli C, Toffolo GM, Dalla Man C, Campioni M, Denti P, Caumo A, et al. Assessment of β-cell function in humans, simultaneously with insulin sensitivity and hepatic extraction from intravenous and oral glucose tests. Am J Physiol Endocrinol Metab. 2007;293:E1-15.
7. D'Allesio DA, Kahn SE, LEusner CR, Ensinck JW. Glucagon-like-peptide 1 enhances glucose tolerance both by stimulation of insulin release and by increasing insulin-independent glucose disposal. J Clin Invest. 1994;93:2263-6.
8. Doyle ME, Egan JM. Glucagon-like peptide-1. Recent Prog Horm Res. 2001;56:377-99.
9. Orskov C, Rabenhoj L, Wettergren A, Kofod H, Holst JJ. Tissue and plasma concentration of amidated and glycin-extended glucagon-like peptide 1 in humans. Diabetes. 1994;43:535-9.
10. Orskov C, Wettergren A, Holst JJ. Secretion of the incretin hormones glucagon-like peptide 1 and gastric inhibitory polypeptide correlates with insulin secretion in normal man throughout the day. Scand J Gastroenterol. 1996;31:665-70.
11. Nauck MA, El-Ouaghlidi A, Gabrys B, Hucking K, Holst JJ, Deacon CF, et al. Secretion of incretin hormones (GIP And GLP-1) and incretin effect after oral glucose in first-degree relatives of patients with type 2 diabetes. Regul Pept. 2004;122:209-17.
12. Tillil H, Shapiro ET, Miller MA, Karrison T, Frank BH, Gallway JA, et al. Dose-dependent effects of oral and intravenous glucose on insulin secretion and clearance in normal humans. Am J Physiol. 1988;254:E349-57.
13. Nauck MA, Homberger E, Siegel EG, Allen RC, Eaton RP, Ebert R, et al. Incretin effects of increasing glucose loads in man calculated from venous insulin and C-peptide responses. J Clin Endocrinol Metab. 1986;63:492-8.
14. Nauck M, Stockmann F, Ebert R, Creutzfeldt W. Reduced incretin effect in type 2 (non-insulin-dependent) diabetes. Diabetologia. 1986;29:46-52.
15. Chan HM, Jain R, Ahren B, Pacini G, D'Ageni DZ. Effects of increasing doses of glucagon-like peptide-1 on insulin-releasing phases during intravenous glucose administration in mice. Am J Physiol Regul Integr Comp Physiol. 2011;300(5):R1126-33.
16. Valdarli I, Nauck MA, Köthe LD, Deacon CF, Holst JJ, Schweizer A, et al. Inhibition of DPP-4 with vildagliptin improved insulin secretion in response to oral as well as "isoglycemic" intravenous glucose without numerically changing the incretin effect in patients with type 2 diabetes. J Clin Endocrinol Metab. 2011;96(4):945-54.
17. Balas B, Baig MR, Watson C, Dunning BE, Ligueros-Sayla M, Wang Y, et al. The dipeptidyl peptidase IV inhibitor vildagliptin suppresses endogenous glucose production and enhances islet function after single-dose administration in type 2 diabetic patients. J Clin Endocrinol Metab. 2007;92(4):1249-55.
18. Knop FK, Vilsboll T, Madsbad S, Holst JJ, Krarup T. Inappropriate suppression of glucagon during OGTT but not during isoglycemic i.v. glucose infusion contributes to the reduced incretin effect in type 2 diabetes mellitus. Diabetologia. 2007;50:797-805.
19. Meier JJ, Deacon CF, Schmidt WE, Holst JJ, Nauck MA. Suppression of glucagon secretion is lower after oral glucose administration than during intravenous glucose administration in human subjects. Diabetologia. 2007;50:806-13.