-
1
-
-
49249089425
-
Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways
-
Fife BT, Bluestone JA. Control of peripheral T-cell tolerance and autoimmunity via the CTLA-4 and PD-1 pathways. Immunol Rev 2008; 224: 166–82.
-
(2008)
Immunol Rev
, vol.224
, pp. 166-182
-
-
Fife, B.T.1
Bluestone, J.A.2
-
2
-
-
45149111788
-
Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy
-
Peggs KS, Quezada SA, Allison JP. Cell intrinsic mechanisms of T-cell inhibition and application to cancer therapy. Immunol Rev 2008; 224: 141–65.
-
(2008)
Immunol Rev
, vol.224
, pp. 141-165
-
-
Peggs, K.S.1
Quezada, S.A.2
Allison, J.P.3
-
3
-
-
84936147067
-
Combined nivolumab and ipilimumab or monotherapy in untreated melanoma
-
Larkin J, Chiarion-Sileni V, Gonzalez R et al. Combined nivolumab and ipilimumab or monotherapy in untreated melanoma. N Engl J Med 2015; 373 (1): 23–34.
-
(2015)
N Engl J Med
, vol.373
, Issue.1
, pp. 23-34
-
-
Larkin, J.1
Chiarion-Sileni, V.2
Gonzalez, R.3
-
4
-
-
84929481481
-
Pembrolizumab versus ipilimumab in advanced melanoma
-
Robert C, Schachter J, Long GV et al. Pembrolizumab versus ipilimumab in advanced melanoma. N Engl J Med 2015; 372 (26): 2521–32.
-
(2015)
N Engl J Med
, vol.372
, Issue.26
, pp. 2521-2532
-
-
Robert, C.1
Schachter, J.2
Long, G.V.3
-
5
-
-
84925222119
-
Nivolumab in previously untreated melanoma without BRAF mutation
-
Robert C, Long GV, Brady B et al. Nivolumab in previously untreated melanoma without BRAF mutation. N Engl J Med 2015; 372 (4): 320–30.
-
(2015)
N Engl J Med
, vol.372
, Issue.4
, pp. 320-330
-
-
Robert, C.1
Long, G.V.2
Brady, B.3
-
6
-
-
77954801079
-
Improved survival with ipilimumab in patients with metastatic melanoma
-
Hodi FS, O'Day SJ, McDermott DF et al. Improved survival with ipilimumab in patients with metastatic melanoma. N Engl J Med 2010; 363 (8): 711–23.
-
(2010)
N Engl J Med
, vol.363
, Issue.8
, pp. 711-723
-
-
Hodi, F.S.1
O'Day, S.J.2
McDermott, D.F.3
-
7
-
-
84944937210
-
Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer
-
Borghaei H, Paz-Ares L, Horn L et al. Nivolumab versus docetaxel in advanced nonsquamous non-small-cell lung cancer. N Engl J Med 2015; 373 (17): 1627–39.
-
(2015)
N Engl J Med
, vol.373
, Issue.17
, pp. 1627-1639
-
-
Borghaei, H.1
Paz-Ares, L.2
Horn, L.3
-
8
-
-
84936791837
-
Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer
-
Brahmer J, Reckamp KL, Baas P et al. Nivolumab versus docetaxel in advanced squamous-cell non-small-cell lung cancer. N Engl J Med 2015; 373 (2): 123–35.
-
(2015)
N Engl J Med
, vol.373
, Issue.2
, pp. 123-135
-
-
Brahmer, J.1
Reckamp, K.L.2
Baas, P.3
-
9
-
-
84946607195
-
Nivolumab versus everolimus in advanced renal-cell carcinoma
-
Motzer RJ, Escudier B, McDermott DF et al. Nivolumab versus everolimus in advanced renal-cell carcinoma. N Engl J Med 2015; 373 (19): 1803–13.
-
(2015)
N Engl J Med
, vol.373
, Issue.19
, pp. 1803-1813
-
-
Motzer, R.J.1
Escudier, B.2
McDermott, D.F.3
-
10
-
-
84959577118
-
Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial
-
Rosenberg JE, Hoffman-Censits J, Powles T et al. Atezolizumab in patients with locally advanced and metastatic urothelial carcinoma who have progressed following treatment with platinum-based chemotherapy: A single-arm, multicentre, phase 2 trial. Lancet 2016; 387 (10031): 1909–20.
-
(2016)
Lancet
, vol.387
, Issue.10031
, pp. 1909-1920
-
-
Rosenberg, J.E.1
Hoffman-Censits, J.2
Powles, T.3
-
11
-
-
58749096691
-
The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation
-
Wolchok JD, Saenger Y. The mechanism of anti-CTLA-4 activity and the negative regulation of T-cell activation. Oncologist 2008; 13 (Suppl 4): 2–9.
-
(2008)
Oncologist
, vol.13
, pp. 2-9
-
-
Wolchok, J.D.1
Saenger, Y.2
-
12
-
-
84950117835
-
Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial
-
Herbst RS, Baas P, Kim D-W et al. Pembrolizumab versus docetaxel for previously treated, PD-L1-positive, advanced non-small-cell lung cancer (KEYNOTE-010): a randomised controlled trial. Lancet 2016; 387 (10027): 1540–50.
-
(2016)
Lancet
, vol.387
, Issue.10027
, pp. 1540-1550
-
-
Herbst, R.S.1
Baas, P.2
Kim, D.-W.3
-
13
-
-
84964573640
-
Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper
-
Champiat S, Lambotte O, Barreau E et al. Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper. Ann Oncol 2016; 27 (4): 559–74.
-
(2016)
Ann Oncol
, vol.27
, Issue.4
, pp. 559-574
-
-
Champiat, S.1
Lambotte, O.2
Barreau, E.3
-
14
-
-
85019333926
-
Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab
-
Menzies AM, Johnson DB, Ramanujam S et al. Anti-PD-1 therapy in patients with advanced melanoma and preexisting autoimmune disorders or major toxicity with ipilimumab. Ann Oncol 2017; 28 (2): 368–76.
-
(2017)
Ann Oncol
, vol.28
, Issue.2
, pp. 368-376
-
-
Menzies, A.M.1
Johnson, D.B.2
Ramanujam, S.3
-
15
-
-
84938205998
-
Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial
-
Ribas A, Puzanov I, Dummer R et al. Pembrolizumab versus investigator-choice chemotherapy for ipilimumab-refractory melanoma (KEYNOTE-002): a randomised, controlled, phase 2 trial. Lancet Oncol 2015; 16 (8): 908–18.
-
(2015)
Lancet Oncol
, vol.16
, Issue.8
, pp. 908-918
-
-
Ribas, A.1
Puzanov, I.2
Dummer, R.3
-
16
-
-
84864052441
-
Management of immune-related adverse events and kinetics of response with ipilimumab
-
Weber JS, Kähler KC, Hauschild A. Management of immune-related adverse events and kinetics of response with ipilimumab. J Clin Oncol 2012; 30 (21): 2691–97.
-
(2012)
J Clin Oncol
, vol.30
, Issue.21
, pp. 2691-2697
-
-
Weber, J.S.1
Kähler, K.C.2
Hauschild, A.3
-
17
-
-
84994430500
-
Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study
-
Langer CJ, Gadgeel SM, Borghaei H et al. Carboplatin and pemetrexed with or without pembrolizumab for advanced, non-squamous non-small-cell lung cancer: a randomised, phase 2 cohort of the open-label KEYNOTE-021 study. Lancet Oncol 2016; 17 (11): 1497–508.
-
(2016)
Lancet Oncol
, vol.17
, Issue.11
, pp. 1497-1508
-
-
Langer, C.J.1
Gadgeel, S.M.2
Borghaei, H.3
-
18
-
-
84964573640
-
Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper
-
Champiat S, Lambotte O, Barreau E et al. Management of immune checkpoint blockade dysimmune toxicities: a collaborative position paper. Ann Oncol 2016; 27 (4): 559–74.
-
(2016)
Ann Oncol
, vol.27
, Issue.4
, pp. 559-574
-
-
Champiat, S.1
Lambotte, O.2
Barreau, E.3
-
19
-
-
84914812931
-
Consensus guidelines for diagnosis, prophylaxis and management of Pneumocystis jirovecii pneumonia in patients with haematological and solid malignancies, 2014
-
Cooley L, Dendle C, Wolf J et al. Consensus guidelines for diagnosis, prophylaxis and management of Pneumocystis jirovecii pneumonia in patients with haematological and solid malignancies, 2014. Intern Med J 2014; 44 (12b): 1350–63.
-
(2014)
Intern Med J
, vol.44
, Issue.12b
, pp. 1350-1363
-
-
Cooley, L.1
Dendle, C.2
Wolf, J.3
-
20
-
-
84944261579
-
Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at Memorial Sloan Kettering Cancer Center
-
Horvat TZ, Adel NG, Dang T-O et al. Immune-related adverse events, need for systemic immunosuppression, and effects on survival and time to treatment failure in patients with melanoma treated with ipilimumab at Memorial Sloan Kettering Cancer Center. J Clin Oncol 2015; 33 (28): 3193–8.
-
(2015)
J Clin Oncol
, vol.33
, Issue.28
, pp. 3193-3198
-
-
Horvat, T.Z.1
Adel, N.G.2
Dang, T.-O.3
-
21
-
-
84942236061
-
Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: a meta-analysis
-
Abdel-Rahman O, ElHalawani H, Fouad M. Risk of cutaneous toxicities in patients with solid tumors treated with immune checkpoint inhibitors: a meta-analysis. Future Oncol 2015; 11 (17): 2471–84.
-
(2015)
Future Oncol
, vol.11
, Issue.17
, pp. 2471-2484
-
-
Abdel-Rahman, O.1
ElHalawani, H.2
Fouad, M.3
-
22
-
-
84937605130
-
Toxicities of immunotherapy for the practitioner
-
Weber JS, Yang JC, Atkins MB, Disis ML. Toxicities of immunotherapy for the practitioner. J Clin Oncol 2015; 33 (18): 2092–9.
-
(2015)
J Clin Oncol
, vol.33
, Issue.18
, pp. 2092-2099
-
-
Weber, J.S.1
Yang, J.C.2
Atkins, M.B.3
Disis, M.L.4
-
23
-
-
84962144656
-
Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor
-
Belum VR, Benhuri B, Postow MA et al. Characterisation and management of dermatologic adverse events to agents targeting the PD-1 receptor. Eur J Cancer. 2016; 60: 12–25.
-
(2016)
Eur J Cancer.
, vol.60
, pp. 12-25
-
-
Belum, V.R.1
Benhuri, B.2
Postow, M.A.3
-
24
-
-
84877093633
-
Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control
-
Robert C, Schadendorf D, Messina M, Hodi FS, O'Day S. Efficacy and safety of retreatment with ipilimumab in patients with pretreated advanced melanoma who progressed after initially achieving disease control. Clin Cancer Res 2013; 19 (8): 2232–9.
-
(2013)
Clin Cancer Res
, vol.19
, Issue.8
, pp. 2232-2239
-
-
Robert, C.1
Schadendorf, D.2
Messina, M.3
Hodi, F.S.4
O'Day, S.5
-
25
-
-
84959231890
-
Diagnosis, monitoring and management of immune-related adverse drug reactions of anti-PD-1 antibody therapy
-
Eigentler TK, Hassel JC, Berking C et al. Diagnosis, monitoring and management of immune-related adverse drug reactions of anti-PD-1 antibody therapy. Cancer Treat Rev 2016; 45: 7–18.
-
(2016)
Cancer Treat Rev
, vol.45
, pp. 7-18
-
-
Eigentler, T.K.1
Hassel, J.C.2
Berking, C.3
-
26
-
-
85026244617
-
-
[Accessed April 2017]. Available from
-
Merck. Pembrolizumab US full prescribing information. 2014. [Accessed April 2017]. Available from: https://www.merck.com/product/usa/pi_circulars/k/keytruda/keytruda_pi.pdf.
-
(2014)
Pembrolizumab US full prescribing information
-
-
-
27
-
-
84860460071
-
-
[Accessed 14 June 2010]. Available from
-
Common Terminology Criteria for Adverse Events (CTCAE). National Cancer Institute. v4.03. [Accessed 14 June 2010]. Available from: http://evs.nci.nih.gov/ftp1/CTCAE/CTCAE_4.03_2010-06-14_QuickReference_5×7.pdf.
-
National Cancer Institute. v4.03
-
-
-
28
-
-
84960155371
-
Toxic epidermal necrolysis-like reaction with severe satellite cell necrosis associated with nivolumab in a patient with ipilimumab refractory metastatic melanoma
-
Nayar N, Briscoe K, Fernandez Penas P. Toxic epidermal necrolysis-like reaction with severe satellite cell necrosis associated with nivolumab in a patient with ipilimumab refractory metastatic melanoma. J Immunother 2016; 39 (3): 149–52.
-
(2016)
J Immunother
, vol.39
, Issue.3
, pp. 149-152
-
-
Nayar, N.1
Briscoe, K.2
Fernandez Penas, P.3
-
29
-
-
84876248304
-
Endocrine side effects induced by immune checkpoint inhibitors
-
Corsello SM, Barnabei A, Marchetti P, De Vecchis L, Salvatori R, Torino F. Endocrine side effects induced by immune checkpoint inhibitors. J Clin Endocrinol Metab 2013; 98 (4): 1361–75.
-
(2013)
J Clin Endocrinol Metab
, vol.98
, Issue.4
, pp. 1361-1375
-
-
Corsello, S.M.1
Barnabei, A.2
Marchetti, P.3
De Vecchis, L.4
Salvatori, R.5
Torino, F.6
-
30
-
-
84982124780
-
Immune checkpoint inhibitor related hypophysitis and endocrine dysfunction: clinical review
-
Joshi MN, Whitelaw BC, Palomar MTP, Wu Y, Carroll PV. Immune checkpoint inhibitor related hypophysitis and endocrine dysfunction: clinical review. Clin Endocrinol 2016; 85 (3): 331–9.
-
(2016)
Clin Endocrinol
, vol.85
, Issue.3
, pp. 331-339
-
-
Joshi, M.N.1
Whitelaw, B.C.2
Palomar, M.T.P.3
Wu, Y.4
Carroll, P.V.5
-
31
-
-
84899873585
-
Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution
-
Ryder M, Callahan M, Postow MA, Wolchok J, Fagin JA. Endocrine-related adverse events following ipilimumab in patients with advanced melanoma: a comprehensive retrospective review from a single institution. Endocr Relat Cancer 2014; 21 (2): 371–81.
-
(2014)
Endocr Relat Cancer
, vol.21
, Issue.2
, pp. 371-381
-
-
Ryder, M.1
Callahan, M.2
Postow, M.A.3
Wolchok, J.4
Fagin, J.A.5
-
32
-
-
84923186196
-
Systemic high-dose corticosteroid treatment does not improve the outcome of ipilimumab-related hypophysitis: a retrospective cohort study
-
Min L, Hodi FS, Giobbie-Hurder A et al. Systemic high-dose corticosteroid treatment does not improve the outcome of ipilimumab-related hypophysitis: a retrospective cohort study. Clin Cancer Res 2015; 21 (4): 749–55.
-
(2015)
Clin Cancer Res
, vol.21
, Issue.4
, pp. 749-755
-
-
Min, L.1
Hodi, F.S.2
Giobbie-Hurder, A.3
-
33
-
-
84949988089
-
Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies
-
Naidoo J, Page DB, Li BT et al. Toxicities of the anti-PD-1 and anti-PD-L1 immune checkpoint antibodies. Ann Oncol 2015; 26 (12): 2375–91.
-
(2015)
Ann Oncol
, vol.26
, Issue.12
, pp. 2375-2391
-
-
Naidoo, J.1
Page, D.B.2
Li, B.T.3
-
34
-
-
85026245976
-
-
[Accessed April 2017]. Available from
-
Genentech. Atezolizumab US full prescribing information. 2016. [Accessed April 2017]. Available from: http://www.gene.com/download/pdf/tecentriq_prescribing.pdf.
-
(2016)
Atezolizumab US full prescribing information
-
-
-
35
-
-
84962385750
-
Anti-PD1 pembrolizumab can induce exceptional fulminant type 1 diabetes
-
Gaudy C, Clévy C, Monestier S et al. Anti-PD1 pembrolizumab can induce exceptional fulminant type 1 diabetes. Diabetes Care 2015; 38 (11): e182–e183.
-
(2015)
Diabetes Care
, vol.38
, Issue.11
, pp. e182-e183
-
-
Gaudy, C.1
Clévy, C.2
Monestier, S.3
-
37
-
-
84879977559
-
Neurological immune-related adverse events of ipilimumab
-
Bot I, Blank CU, Boogerd W, Brandsma D. Neurological immune-related adverse events of ipilimumab. Pract Neurol 2013; 13 (4): 278–80.
-
(2013)
Pract Neurol
, vol.13
, Issue.4
, pp. 278-280
-
-
Bot, I.1
Blank, C.U.2
Boogerd, W.3
Brandsma, D.4
-
38
-
-
85026238187
-
-
[updated October 2015]. [Accessed March 2017]. Available from
-
BMS. Ipilimumab US full prescribing information. 2011. [updated October 2015]. [Accessed March 2017]. Available from: http://packageinserts.bms.com/pi/pi_yervoy.pdf.
-
(2011)
Ipilimumab US full prescribing information
-
-
-
39
-
-
84933678156
-
Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial
-
Eggermont AMM, Chiarion-Sileni V, Grob J-J et al. Adjuvant ipilimumab versus placebo after complete resection of high-risk stage III melanoma (EORTC 18071): a randomised, double-blind, phase 3 trial. Lancet Oncol 2015; 16 (5): 522–30.
-
(2015)
Lancet Oncol
, vol.16
, Issue.5
, pp. 522-530
-
-
Eggermont, A.M.M.1
Chiarion-Sileni, V.2
Grob, J.-J.3
-
40
-
-
84931083080
-
Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial
-
Weber JS, D'Angelo SP, Minor D et al. Nivolumab versus chemotherapy in patients with advanced melanoma who progressed after anti-CTLA-4 treatment (CheckMate 037): a randomised, controlled, open-label, phase 3 trial. Lancet Oncol 2015; 16 (4): 375–84.
-
(2015)
Lancet Oncol
, vol.16
, Issue.4
, pp. 375-384
-
-
Weber, J.S.1
D'Angelo, S.P.2
Minor, D.3
-
41
-
-
78650428877
-
Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma
-
Berman D, Parker SM, Siegel J et al. Blockade of cytotoxic T-lymphocyte antigen-4 by ipilimumab results in dysregulation of gastrointestinal immunity in patients with advanced melanoma. Cancer Immun 2010; 10: 11.
-
(2010)
Cancer Immun
, vol.10
, pp. 11
-
-
Berman, D.1
Parker, S.M.2
Siegel, J.3
-
42
-
-
85026248669
-
-
[updated May 2016]. [Accessed April 2017]. Available from
-
BMS. Nivolumab US full prescribing information. 2014. [updated May 2016]. [Accessed April 2017]. Available from: http://packageinserts.bms.com/pi/pi_opdivo.pdf.
-
(2014)
Nivolumab US full prescribing information
-
-
-
43
-
-
84964355523
-
Melanoma, Version 2., NCCN clinical practice guidelines in oncology
-
Coit DG, Thompson JA, Algazi A et al. Melanoma, Version 2., NCCN clinical practice guidelines in oncology. J Natl Compr Canc Netw. 2016; 14 (4): 450–73.
-
(2016)
J Natl Compr Canc Netw.
, vol.14
, Issue.4
, pp. 450-473
-
-
Coit, D.G.1
Thompson, J.A.2
Algazi, A.3
-
44
-
-
84974663028
-
Pancreatitis secondary to anti-programmed death receptor 1 immunotherapy diagnosed by FDG PET/CT
-
Alabed YZ, Aghayev A, Sakellis C, Van den Abbeele AD. Pancreatitis secondary to anti-programmed death receptor 1 immunotherapy diagnosed by FDG PET/CT. Clin Nucl Med 2015; 40 (11): e528–e529.
-
(2015)
Clin Nucl Med
, vol.40
, Issue.11
, pp. e528-e529
-
-
Alabed, Y.Z.1
Aghayev, A.2
Sakellis, C.3
Van den Abbeele, A.D.4
-
45
-
-
67349182592
-
Therapeutic efficacy of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with metastatic melanoma unresponsive to prior systemic treatments: clinical and immunological evidence from three patient cases
-
Di Giacomo AM, Danielli R, Guidoboni M et al. Therapeutic efficacy of ipilimumab, an anti-CTLA-4 monoclonal antibody, in patients with metastatic melanoma unresponsive to prior systemic treatments: clinical and immunological evidence from three patient cases. Cancer Immunol Immunother 2009; 58 (8): 1297–306.
-
(2009)
Cancer Immunol Immunother
, vol.58
, Issue.8
, pp. 1297-1306
-
-
Di Giacomo, A.M.1
Danielli, R.2
Guidoboni, M.3
-
46
-
-
85014010627
-
Pneumonitis in patients treated with anti-programmed death-1/programmed death ligand 1 therapy
-
Naidoo J, Wang X, Woo KM et al. Pneumonitis in patients treated with anti-programmed death-1/programmed death ligand 1 therapy. J Clin Oncol 2017; 35 (7): 709–17.
-
(2017)
J Clin Oncol
, vol.35
, Issue.7
, pp. 709-717
-
-
Naidoo, J.1
Wang, X.2
Woo, K.M.3
-
47
-
-
84938741949
-
Emerging immunotherapies in the treatment of non-small cell lung cancer (NSCLC): the role of immune checkpoint inhibitors
-
Langer CJ. Emerging immunotherapies in the treatment of non-small cell lung cancer (NSCLC): the role of immune checkpoint inhibitors. Am J Clin Oncol 2015; 38 (4): 422–30.
-
(2015)
Am J Clin Oncol
, vol.38
, Issue.4
, pp. 422-430
-
-
Langer, C.J.1
-
48
-
-
84973573023
-
Risk of pneumonitis in cancer patients treated with immune checkpoint inhibitors: a meta-analysis
-
Abdel-Rahman O, Fouad M. Risk of pneumonitis in cancer patients treated with immune checkpoint inhibitors: a meta-analysis. Ther Adv Respir Dis 2016; 10 (3): 183–93.
-
(2016)
Ther Adv Respir Dis
, vol.10
, Issue.3
, pp. 183-193
-
-
Abdel-Rahman, O.1
Fouad, M.2
-
49
-
-
84936749833
-
Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer
-
Gettinger SN, Horn L, Gandhi L et al. Overall survival and long-term safety of nivolumab (anti-programmed death 1 antibody, BMS-936558, ONO-4538) in patients with previously treated advanced non-small-cell lung cancer. J Clin Oncol 2015; 33 (18): 2004–12.
-
(2015)
J Clin Oncol
, vol.33
, Issue.18
, pp. 2004-2012
-
-
Gettinger, S.N.1
Horn, L.2
Gandhi, L.3
-
50
-
-
84937053577
-
Anti-PD-1-related pneumonitis during cancer immunotherapy
-
Nishino M, Sholl LM, Hodi FS, Hatabu H, Ramaiya NH. Anti-PD-1-related pneumonitis during cancer immunotherapy. N Engl J Med 2015; 373 (3): 288–90.
-
(2015)
N Engl J Med
, vol.373
, Issue.3
, pp. 288-290
-
-
Nishino, M.1
Sholl, L.M.2
Hodi, F.S.3
Hatabu, H.4
Ramaiya, N.H.5
-
51
-
-
84937972006
-
Hepatotoxicity of green tea: an update
-
Mazzanti G, Di Sotto A, Vitalone A. Hepatotoxicity of green tea: an update. Arch Toxicol 2015; 89 (8): 1175–91.
-
(2015)
Arch Toxicol
, vol.89
, Issue.8
, pp. 1175-1191
-
-
Mazzanti, G.1
Di Sotto, A.2
Vitalone, A.3
-
52
-
-
84941615057
-
Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade
-
Buchbinder E, Hodi FS. Cytotoxic T lymphocyte antigen-4 and immune checkpoint blockade. J Clin Invest 2015; 125 (9): 3377–83.
-
(2015)
J Clin Invest
, vol.125
, Issue.9
, pp. 3377-3383
-
-
Buchbinder, E.1
Hodi, F.S.2
-
53
-
-
84879141840
-
A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C
-
Sangro B, Gomez-Martin C, de la Mata M et al. A clinical trial of CTLA-4 blockade with tremelimumab in patients with hepatocellular carcinoma and chronic hepatitis C. J Hepatol 2013; 59 (1): 81–8.
-
(2013)
J Hepatol
, vol.59
, Issue.1
, pp. 81-88
-
-
Sangro, B.1
Gomez-Martin, C.2
de la Mata, M.3
-
54
-
-
84878089612
-
A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection
-
Gardiner D, Lalezari J, Lawitz E et al. A randomized, double-blind, placebo-controlled assessment of BMS-936558, a fully human monoclonal antibody to programmed death-1 (PD-1), in patients with chronic hepatitis C virus infection. Plos One 2013; 8 (5): e63818.
-
(2013)
Plos One
, vol.8
, Issue.5
-
-
Gardiner, D.1
Lalezari, J.2
Lawitz, E.3
-
55
-
-
84955183087
-
Present and future therapies of hepatitis B: from discovery to cure
-
Liang TJ, Block TM, McMahon BJ et al. Present and future therapies of hepatitis B: from discovery to cure. Hepatology 2015; 62 (6): 1893–908.
-
(2015)
Hepatology
, vol.62
, Issue.6
, pp. 1893-1908
-
-
Liang, T.J.1
Block, T.M.2
McMahon, B.J.3
-
56
-
-
84956788879
-
HCV in 2015: advances in hepatitis C research and treatment
-
Rehermann B. HCV in 2015: advances in hepatitis C research and treatment. Nat Rev Gastroenterol Hepatol 2016; 13 (2): 70–2.
-
(2016)
Nat Rev Gastroenterol Hepatol
, vol.13
, Issue.2
, pp. 70-72
-
-
Rehermann, B.1
-
57
-
-
84994383033
-
Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors
-
Cortazar FB, Marrone KA, Troxell ML et al. Clinicopathological features of acute kidney injury associated with immune checkpoint inhibitors. Kidney Int 2016; 90 (3): 638–47.
-
(2016)
Kidney Int
, vol.90
, Issue.3
, pp. 638-647
-
-
Cortazar, F.B.1
Marrone, K.A.2
Troxell, M.L.3
-
58
-
-
84904553412
-
Kidney injuries related to ipilimumab
-
Izzedine H, Gueutin V, Gharbi C et al. Kidney injuries related to ipilimumab. Invest New Drugs 2014; 32 (4): 769–73.
-
(2014)
Invest New Drugs
, vol.32
, Issue.4
, pp. 769-773
-
-
Izzedine, H.1
Gueutin, V.2
Gharbi, C.3
-
59
-
-
84919828890
-
Late-onset paraplegia after complete response to two cycles of ipilimumab for metastatic melanoma
-
O'Kane GM, Lyons TG, Colleran GC et al. Late-onset paraplegia after complete response to two cycles of ipilimumab for metastatic melanoma. Oncol Res Treat 2014; 37 (12): 757–60.
-
(2014)
Oncol Res Treat
, vol.37
, Issue.12
, pp. 757-760
-
-
O'Kane, G.M.1
Lyons, T.G.2
Colleran, G.C.3
-
60
-
-
84922698461
-
Vogt–Koyanagi–Harada-like syndrome after CTLA-4 inhibition with ipilimumab for metastatic melanoma
-
Crosson JN, Laird PW, Debiec M, Bergstrom CS, Lawson DH, Yeh S. Vogt–Koyanagi–Harada-like syndrome after CTLA-4 inhibition with ipilimumab for metastatic melanoma. J Immunother 2015; 38 (2): 80–4.
-
(2015)
J Immunother
, vol.38
, Issue.2
, pp. 80-84
-
-
Crosson, J.N.1
Laird, P.W.2
Debiec, M.3
Bergstrom, C.S.4
Lawson, D.H.5
Yeh, S.6
-
61
-
-
84896934432
-
Atypical neurological complications of ipilimumab therapy in patients with metastatic melanoma
-
Liao B, Shroff S, Kamiya-Matsuoka C, Tummala S. Atypical neurological complications of ipilimumab therapy in patients with metastatic melanoma. Neuro-Oncol 2014; 16 (4): 589–93.
-
(2014)
Neuro-Oncol
, vol.16
, Issue.4
, pp. 589-593
-
-
Liao, B.1
Shroff, S.2
Kamiya-Matsuoka, C.3
Tummala, S.4
-
62
-
-
84962409041
-
Limbic encephalitis following immunotherapy against metastatic malignant melanoma
-
Salam S, Lavin T, Turan A. Limbic encephalitis following immunotherapy against metastatic malignant melanoma. BMJ Case Rep 2016, https://doi.org/10.1136/bcr-2016-215012.
-
(2016)
BMJ Case Rep
-
-
Salam, S.1
Lavin, T.2
Turan, A.3
-
63
-
-
84961786652
-
Immunotherapy-associated hemolytic anemia with pure red-cell aplasia
-
Nair R, Gheith S, Nair SG. Immunotherapy-associated hemolytic anemia with pure red-cell aplasia. N Engl J Med 2016; 374 (11): 1096–7.
-
(2016)
N Engl J Med
, vol.374
, Issue.11
, pp. 1096-1097
-
-
Nair, R.1
Gheith, S.2
Nair, S.G.3
-
64
-
-
84904177881
-
Serious haematological toxicity during and after ipilimumab treatment: a case series
-
Simeone E, Grimaldi AM, Esposito A et al. Serious haematological toxicity during and after ipilimumab treatment: a case series. J Med Case Rep 2014; 8: 240.
-
(2014)
J Med Case Rep
, vol.8
, pp. 240
-
-
Simeone, E.1
Grimaldi, A.M.2
Esposito, A.3
-
65
-
-
80455173518
-
Hemophilia A induced by ipilimumab
-
Delyon J, Mateus C, Lambert T. Hemophilia A induced by ipilimumab. N Engl J Med 2011; 365 (18): 1747–8.
-
(2011)
N Engl J Med
, vol.365
, Issue.18
, pp. 1747-1748
-
-
Delyon, J.1
Mateus, C.2
Lambert, T.3
-
66
-
-
84962957512
-
Ipilimumab-induced ocular and orbital inflammation—A case series and review of the literature
-
Papavasileiou E, Prasad S, Freitag SK, Sobrin L, Lobo A-M. Ipilimumab-induced ocular and orbital inflammation—A case series and review of the literature. Ocular Immunol Inflamm 2015; 2: 1–7.
-
(2015)
Ocular Immunol Inflamm
, vol.2
, pp. 1-7
-
-
Papavasileiou, E.1
Prasad, S.2
Freitag, S.K.3
Sobrin, L.4
Lobo, A.-M.5
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