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1
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77954801079
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Improved survival with ipilimumab in patients with metastatic melanoma
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10.1056/NEJMoa1003466 20525992
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Improved survival with ipilimumab in patients with metastatic melanoma. Hodi FS, O'Day SJ, McDermott DF, Weber RW, Sosman JA, Haanen JB, Gonzalez R, Robert C, Schadendorf D, Hassel JC, Akerley W, van den Eertwegh AJ, Lutzky J, Lorigan P, Vaubel JM, Linette GP, Hogg D, Ottensmeier CH, Lebbé C, Peschel C, Quirt I, Clark JI, Wolchok JD, Weber JS, Tian J, Yellin MJ, Nichol GM, Hoos A, Urba WJ, N Engl J Med 2010 363 711 723 10.1056/NEJMoa1003466 20525992
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Hodi, F.S.1
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McDermott, D.F.3
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Haanen, J.B.6
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Hassel, J.C.10
Akerley, W.11
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Hogg, D.17
Ottensmeier, C.H.18
Lebbé, C.19
Peschel, C.20
Quirt, I.21
Clark, J.I.22
Wolchok, J.D.23
Weber, J.S.24
Tian, J.25
Yellin, M.J.26
Nichol, G.M.27
Hoos, A.28
Urba, W.J.29
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2
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79959772576
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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma
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10.1056/NEJMoa1104621 21639810
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Ipilimumab plus dacarbazine for previously untreated metastatic melanoma. Robert C, Thomas L, Bondarenko I, O'Day S, Weber J, Garbe C, Lebbe C, Baurain JF, Testori A, Grob JJ, Davidson N, Richards J, Maio M, Hauschild A, Miller WH Jr, Gascon P, Lotem M, Harmankaya K, Ibrahim R, Francis S, Chen TT, Humphrey R, Hoos A, Wolchok JD, N Engl J Med 2011 364 2517 2526 10.1056/NEJMoa1104621 21639810
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N Engl J Med
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Robert, C.1
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Bondarenko, I.3
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Weber, J.5
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Baurain, J.F.8
Testori, A.9
Grob, J.J.10
Davidson, N.11
Richards, J.12
Maio, M.13
Hauschild, A.14
Miller Jr., W.H.15
Gascon, P.16
Lotem, M.17
Harmankaya, K.18
Ibrahim, R.19
Francis, S.20
Chen, T.T.21
Humphrey, R.22
Hoos, A.23
Wolchok, J.D.24
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3
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84856008240
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Ipilimumab safety profile: Summary of findings from completed trials in advanced melanoma
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Abstract 8583
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Ipilimumab safety profile: summary of findings from completed trials in advanced melanoma. Ibrahim R, Berman D, de Pril V, Humphrey RW, Chen T, Messina M, Chin KM, Liu HY, Bielefield M, Hoos A, J Clin Oncol 2011 29 Suppl Abstract 8583
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J Clin Oncol
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Ibrahim, R.1
Berman, D.2
De Pril, V.3
Humphrey, R.W.4
Chen, T.5
Messina, M.6
Chin, K.M.7
Liu, H.Y.8
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Hoos, A.10
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4
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84872339660
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The price of tumor control: An analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network
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10.1371/journal.pone.0053745 23341990
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The price of tumor control: an analysis of rare side effects of anti-CTLA-4 therapy in metastatic melanoma from the ipilimumab network. Voskens CJ, Goldinger SM, Loquai C, Robert C, Kaehler KC, Berking C, Bergmann T, Bockmeyer CL, Eigentler T, Fluck M, Garbe C, Gutzmer R, Grabbe S, Hauschild A, Hein R, Hundorfean G, Justich A, Keller U, Klein C, Mateus C, Mohr P, Paetzold S, Satzger I, Schadendorf D, Schlaeppi M, Schuler G, Schuler-Thurner B, Trefzer U, Ulrich J, Vaubel J, et al. PLoS One 2013 8 53745 10.1371/journal.pone.0053745 23341990
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Voskens, C.J.1
Goldinger, S.M.2
Loquai, C.3
Robert, C.4
Kaehler, K.C.5
Berking, C.6
Bergmann, T.7
Bockmeyer, C.L.8
Eigentler, T.9
Fluck, M.10
Garbe, C.11
Gutzmer, R.12
Grabbe, S.13
Hauschild, A.14
Hein, R.15
Hundorfean, G.16
Justich, A.17
Keller, U.18
Klein, C.19
Mateus, C.20
Mohr, P.21
Paetzold, S.22
Satzger, I.23
Schadendorf, D.24
Schlaeppi, M.25
Schuler, G.26
Schuler-Thurner, B.27
Trefzer, U.28
Ulrich, J.29
Vaubel, J.30
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5
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67349240111
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Immune-mediated red cell aplasia after anti-CTLA-4 immunotherapy for metastatic melanoma
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10.1007/s00262-008-0627-x 19052742
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Immune-mediated red cell aplasia after anti-CTLA-4 immunotherapy for metastatic melanoma. Gordon IO, Wade T, Chin K, Dickstein J, Gajewski TF, Cancer Immunol Immunother 2009 58 1351 1353 10.1007/s00262-008-0627-x 19052742
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Cancer Immunol Immunother
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Gordon, I.O.1
Wade, T.2
Chin, K.3
Dickstein, J.4
Gajewski, T.F.5
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67449091389
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Neutropenia in a patient treated with ipilimumab (anti-CTLA-4 antibody)
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10.1097/CJI.0b013e31819aa40b 19242368
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Neutropenia in a patient treated with ipilimumab (anti-CTLA-4 antibody). Akhtari M, Waller EK, Jaye DL, Lawson DH, Ibrahim R, Papadopoulos NE, Arellano ML, J Immunother 2009 32 322 324 10.1097/CJI.0b013e31819aa40b 19242368
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J Immunother
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Akhtari, M.1
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Lawson, D.H.4
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Papadopoulos, N.E.6
Arellano, M.L.7
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7
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84904204930
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Large granular lymphocytosis with severe neutropenia following ipilimumab therapy for metastatic melanoma
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10.1186/2162-3619-1-3 23210632
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Large granular lymphocytosis with severe neutropenia following ipilimumab therapy for metastatic melanoma. Wei G, Nwakuche U, Cadavid G, Ajaz A, Seiter K, Liu D, Exp Hematol Oncol 2012 1 1 3 10.1186/2162-3619-1-3 23210632
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Exp Hematol Oncol
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Wei, G.1
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8
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84891274873
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Efficacy, safety, and correlation with mutation status in metastatic melanoma patients
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Italian cohort of ipilimumab expanded access programme (EAP) Abstract 9070
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Efficacy, safety, and correlation with mutation status in metastatic melanoma patients. Queirolo P, Spagnolo F, Altomonte M, Chiarion-Sileni V, Pigozzo J, Del Vecchio M, Di Guardo L, Ridolfi R, Scoppola A, Ferrucci PF, Ferraresi V, Bernengo MG, Guida M, Marconcini R, Mandalà M, Parmiani G, Rinaldi G, Aglietta M, Simeone E, Ascierto PA, Italian cohort of ipilimumab expanded access programme (EAP), J Clin Oncol 2013 31 Suppl Abstract 9070
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J Clin Oncol
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Queirolo, P.1
Spagnolo, F.2
Altomonte, M.3
Chiarion-Sileni, V.4
Pigozzo, J.5
Del Vecchio, M.6
Di Guardo, L.7
Ridolfi, R.8
Scoppola, A.9
Ferrucci, P.F.10
Ferraresi, V.11
Bernengo, M.G.12
Guida, M.13
Marconcini, R.14
Mandalà, M.15
Parmiani, G.16
Rinaldi, G.17
Aglietta, M.18
Simeone, E.19
Ascierto, P.A.20
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9
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84864052441
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Management of immune-related adverse events and kinetics of response with ipilimumab
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10.1200/JCO.2012.41.6750 22614989
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Management of immune-related adverse events and kinetics of response with ipilimumab. Weber JS, Kähler KC, Hauschild A, J Clin Oncol 2012 30 2691 2697 10.1200/JCO.2012.41.6750 22614989
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J Clin Oncol
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Weber, J.S.1
Kähler, K.C.2
Hauschild, A.3
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84874605864
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Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma
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10.1200/JCO.2012.44.6112 23295794
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Phase III randomized clinical trial comparing tremelimumab with standard-of-care chemotherapy in patients with advanced melanoma. Ribas A, Kefford R, Marshall MA, Punt CJ, Haanen JB, Marmol M, Garbe C, Gogas H, Schachter J, Linette G, Lorigan P, Kendra KL, Maio M, Trefzer U, Smylie M, McArthur GA, Dreno B, Nathan PD, Mackiewicz J, Kirkwood JM, Gomez-Navarro J, Huang B, Pavlov D, Hauschild A, J Clin Oncol 2013 31 616 622 10.1200/JCO.2012.44.6112 23295794
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J Clin Oncol
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Ribas, A.1
Kefford, R.2
Marshall, M.A.3
Punt, C.J.4
Haanen, J.B.5
Marmol, M.6
Garbe, C.7
Gogas, H.8
Schachter, J.9
Linette, G.10
Lorigan, P.11
Kendra, K.L.12
Maio, M.13
Trefzer, U.14
Smylie, M.15
McArthur, G.A.16
Dreno, B.17
Nathan, P.D.18
Mackiewicz, J.19
Kirkwood, J.M.20
Gomez-Navarro, J.21
Huang, B.22
Pavlov, D.23
Hauschild, A.24
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11
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84876678621
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Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: Detailed safety analysis from a phase 3 trial in patients with advanced melanoma
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10.1002/cncr.27969 23400564
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Patterns of onset and resolution of immune-related adverse events of special interest with ipilimumab: detailed safety analysis from a phase 3 trial in patients with advanced melanoma. Weber JS, Dummer R, de Pril V, Lebbé C, Hodi FS, MDX010-20 Investigators, Cancer 2013 119 1675 1682 10.1002/cncr.27969 23400564
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Cancer
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Weber, J.S.1
Dummer, R.2
De Pril, V.3
Lebbé, C.4
Hodi, F.S.5
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12
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77953475151
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Association between immune-related adverse events (irAEs) and disease control or overall survival in patients (pts) with advanced melanoma treated with 10mg/kg ipilimumab in three phase II clinical trials
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Abstract 9034
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Association between immune-related adverse events (irAEs) and disease control or overall survival in patients (pts) with advanced melanoma treated with 10mg/kg ipilimumab in three phase II clinical trials. Lutzky J, Wolchok J, Hamid O, Lebbe C, Pehamberger H, Linette G, de Pril V, Ibrahim R, Hoos A, O'Day S, J Clin Oncol 2009 27 Suppl Abstract 9034
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J Clin Oncol
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Lutzky, J.1
Wolchok, J.2
Hamid, O.3
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Pehamberger, H.5
Linette, G.6
De Pril, V.7
Ibrahim, R.8
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13
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84891274274
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Correlation between efficacy and toxicity in pts with pretreated advanced melanoma treated within the Italian cohort of the ipilimumab expanded access programme (EAP)
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Abstract 9065
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Correlation between efficacy and toxicity in pts with pretreated advanced melanoma treated within the Italian cohort of the ipilimumab expanded access programme (EAP). Di Giacomo AM, Grimaldi AM, Ascierto PA, Queirolo P, Del Vecchio M, Ridolfi R, De Rosa F, De Galitiis F, Testori A, Cognetti F, Bernengo MG, Savoia P, Guida M, Strippoli S, Galli L, Mandala M, Parmiani G, Rinaldi G, Aglietta M, Chiarion-Sileni V, J Clin Oncol 2013 31 Suppl Abstract 9065
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J Clin Oncol
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Di Giacomo, A.M.1
Grimaldi, A.M.2
Ascierto, P.A.3
Queirolo, P.4
Del Vecchio, M.5
Ridolfi, R.6
De Rosa, F.7
De Galitiis, F.8
Testori, A.9
Cognetti, F.10
Bernengo, M.G.11
Savoia, P.12
Guida, M.13
Strippoli, S.14
Galli, L.15
Mandala, M.16
Parmiani, G.17
Rinaldi, G.18
Aglietta, M.19
Chiarion-Sileni, V.20
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