Effect of Pulsatility on Microcirculation in Patients Treated with Extracorporeal Cardiopulmonary Resuscitation: A Pilot Study

ASAIO Journal

Volumn 63, Issue 4, 2017, Pages 386-391

  Krupičková, Petra ^a,b   Huptych, Michal ^b   Mormanová, Zuzana ^c   Bouček, Tomáš ^d   Belza, Tomáš ^a   Šmíd, Ondřej ^e   Král, Aleš ^e   Skalická, Hana ^e   Linhart, Aleš ^e   Bělohlávek, Jan ^e  

^a CHARLES UNIVERSITY   (Czech Republic)

^b UNIVERSITY HOSPITAL MOTOL   (Czech Republic)

^c CZECH TECHNICAL UNIVERSITY IN PRAGUE   (Czech Republic)

^d Krajska Nemocnice Liberec   (Czech Republic)

^e CHARLES UNIVERSITY   (Czech Republic)

Author keywords

ECMO; extracorporeal CPR; microcirculation; pulsatile blood flow; SDF

Indexed keywords

BLOOD; HEMODYNAMICS; PATIENT MONITORING; PATIENT TREATMENT; PULSATILE FLOW; RESPIRATORY THERAPY; RESUSCITATION;

CARDIOPULMONARY RESUSCITATION; ECMO; EXTRACORPOREAL CPR; EXTRACORPOREAL MEMBRANE OXYGENATION; HEMODYNAMIC PARAMETERS; MICROCIRCULATORY BLOOD FLOWS; OBSERVATIONAL STUDY; PULSATILE BLOOD FLOW;

MICROCIRCULATION;

ADULT; ARTERY CATHETER; ARTICLE; BLOOD FLOW; BLOOD PRESSURE MEASUREMENT; CAPILLARY DENSITY; CARDIOPULMONARY HEMODYNAMICS; CENTRAL VENOUS PRESSURE; CLINICAL ARTICLE; CONTROLLED STUDY; EXTRACORPOREAL OXYGENATION; FEMALE; HEART ARREST; HEART LEFT VENTRICLE EJECTION FRACTION; HUMAN; IMAGE ANALYSIS; IMAGE QUALITY; IMAGING SOFTWARE; MALE; MEAN ARTERIAL PRESSURE; MICROCIRCULATION; MIDDLE AGED; OBSERVATIONAL STUDY; PILOT STUDY; PRIORITY JOURNAL; PULSATILITY INDEX; PULSE PRESSURE; RESUSCITATION; RETURN OF SPONTANEOUS CIRCULATION; AGED; PHYSIOLOGY; PROCEDURES; PULSATILE FLOW;

ADULT; AGED; CARDIOPULMONARY RESUSCITATION; EXTRACORPOREAL MEMBRANE OXYGENATION; FEMALE; HEART ARREST; HUMANS; MALE; MICROCIRCULATION; MIDDLE AGED; PILOT PROJECTS; PULSATILE FLOW;

EID: 85021872899     PISSN: 10582916     EISSN: 1538943X     Source Type: Journal    
DOI: 10.1097/MAT.0000000000000492     Document Type: Article

References (25)

1. Sakamoto T, Morimura N, Nagao K, et al; SAVE-J Study Group: Extracorporeal cardiopulmonary resuscitation versus conventional cardiopulmonary resuscitation in adults with outof-hospital cardiac arrest: A prospective observational study. Resuscitation 85: 762-768, 2014.
2. Mosier JM, Kelsey M, Raz Y, et al: Extracorporeal membrane oxygenation (ECMO) for critically ill adults in the emergency department: History, current applications, and future directions. Crit Care 19: 431, 2015.
3. Le Guen M, Nicolas-Robin A, Carreira S, et al: Extracorporeal life support following out-of-hospital refractory cardiac arrest. Crit Care 15: R29, 2011.
4. Bělohlávek J, Mlček M, Huptych M, et al: Coronary versus carotid blood flow and coronary perfusion pressure in a pig model of prolonged cardiac arrest treated by different modes of venoarterial ECMO and intraaortic balloon counterpulsation. Crit Care 16: R50, 2012.
5. Ro SK, Kim JB, Jung SH, Choo SJ, Chung CH, Lee JW: Extracorporeal life support for cardiogenic shock: Influence of concomitant intra-aortic balloon counterpulsation. Eur J Cardiothorac Surg 46: 186-192; discussion 192, 2014.
6. Munsterman LD, Elbers PW, Ozdemir A, van Dongen EP, van Iterson M, Ince C: Withdrawing intra-aortic balloon pump support paradoxically improves microvascular flow. Crit Care 14: R161, 2010.
7. J ung C, Rödiger C, Fritzenwanger M, et al: Acute microflow changes after stop and restart of intra-aortic balloon pump in cardiogenic shock. Clin Res Cardiol 98: 469-475, 2009.
8. Petroni T, Harrois A, Amour J, et al: Intra-aortic balloon pump effects on macrocirculation and microcirculation in cardiogenic shock patients supported by venoarterial extracorporeal membrane oxygenation∗. Crit Care Med 42: 2075-2082, 2014.
9. Y ang F, Jia ZS, Xing JL, et al: Effects of intra-aortic balloon pump on cerebral blood flow during peripheral venoarterial extracorporeal membrane oxygenation support. J Transl Med 12: 106, 2014.
10. U ndar A, Frazier OH, Fraser CD, Jr.: Defining pulsatile perfusion: Quantification in terms of energy equivalent pressure. Artif Organs 23: 712-716, 1999.
11. Belohlavek J, Kucera K, Jarkovsky J, et al: Hyperinvasive approach to out-of hospital cardiac arrest using mechanical chest compression device, prehospital intraarrest cooling, extracorporeal life support and early invasive assessment compared to standard of care. A randomized parallel groups comparative study proposal. "Prague OHCA study". J Transl Med 10: 163, 2012.
12. Cummins RO, Chamberlain DA, Abramson NS, et al: Recommended guidelines for uniform reporting of data from out-of-hospital cardiac arrest: The Utstein Style. A statement for health professionals from a task force of the American Heart Association, the European Resuscitation Council, the Heart and Stroke Foundation of Canada, and the Australian Resuscitation Council. Circulation 84: 960-975, 1991.
13. Goedhart PT, Khalilzada M, Bezemer R, Merza J, Ince C: Sidestream Dark Field (SDF) imaging: A novel stroboscopic LED ring-based imaging modality for clinical assessment of the microcirculation. Opt Express 15: 15101-15114, 2007.
14. D e Backer D, Hollenberg S, Boerma C, et al: How to evaluate the microcirculation: Report of a round table conference. Critical care (London, England) 11: R101, 2007.
15. van Genderen ME, Lima A, Akkerhuis M, Bakker J, van Bommel J: Persistent peripheral and microcirculatory perfusion alterations after out-of-hospital cardiac arrest are associated with poor survival. Crit Care Med 40: 2287-2294, 2012.
16. Koopmans M, Kuiper MA, Endeman H, et al: Microcirculatory perfusion and vascular reactivity are altered in post cardiac arrest patients, irrespective of target temperature management to 33 °C vs 36 °C. Resuscitation 86: 14-18, 2015.
17. D onadello K, Favory R, Salgado-Ribeiro D, et al: Sublingual and muscular microcirculatory alterations after cardiac arrest: A pilot study. Resuscitation 82: 690-695, 2011.
18. den Uil CA, Maat AP, Lagrand WK, et al: Mechanical circulatory support devices improve tissue perfusion in patients with endstage heart failure or cardiogenic shock. J Heart Lung Transplant 28: 906-911, 2009.
19. Lam K, Sjauw KD, Henriques JP, Ince C, de Mol BA: Improved microcirculation in patients with an acute ST-elevation myocardial infarction treated with the Impella LP2.5 percutaneous left ventricular assist device. Clin Res Cardiol 98: 311-318, 2009.
20. Schinagl CM, Mormanova ZH, Puchwein-Schwepcke A, Schmid I, Genzel-Boroviczény O: The effect of red blood cell transfusion on the microcirculation of anemic children. Eur J Pediatr 175: 793-798, 2016.
21. Y uruk K, Almac E, Bezemer R, Goedhart P, de Mol B, Ince C: Blood transfusions recruit the microcirculation during cardiac surgery. Transfusion 51: 961-967, 2011.
22. Boerma EC, Ince C: The role of vasoactive agents in the resuscitation of microvascular perfusion and tissue oxygenation in critically ill patients. Intensive Care Med 36: 2004-2018, 2010.
23. den Uil CA, Lagrand WK, van der Ent M, et al: Impaired microcirculation predicts poor outcome of patients with acute myocardial infarction complicated by cardiogenic shock. Eur Heart J 31: 3032-3039, 2010.
24. Barić D: Why pulsatility still matters: A review of current knowledge. Croat Med J 55: 609-620, 2014.
25. Petersen SM, Greisen G, Hyttel-Sorensen S, Hahn GH: Sidestream dark field images of the microcirculation: Intra-observer reliability and correlation between two semi-quantitative methods for determining flow. BMC Med Imaging 14: 14, 2014.