Copy number variation of functional RBMY1 is associated with sperm motility: An azoospermia factor-linked candidate for asthenozoospermia

Human Reproduction

Volumn 32, Issue 7, 2017, Pages 1521-1531

  Yan, Yuanlong ^a   Yang, Xiling ^a   Liu, Yunqiang ^a   Shen, Ying ^a   Tu, Wenling ^a   Dong, Qiang ^a   Yang, Dong ^b   Ma, Yongyi ^c   Yang, Yuan ^a  

^a SICHUAN UNIVERSITY   (China)

^b CHENGDU WOMEN S AND CHILDREN S CENTRAL HOSPITAL   (China)

^c Qingbaijiang Maternal and Child Health Hospital   (China)

Author keywords

asthenozoospermia; azoospermia factor; copy conversion; copy number variation; male infertility; RBMY1; sperm motility; Y chromosome haplogroup

Indexed keywords

LIGANDIN; MESSENGER RNA; RNA BINDING MOTIF PROTEIN Y LINKED FAMILY 1; UNCLASSIFIED DRUG; NUCLEAR PROTEIN; RBMY1A1 PROTEIN, HUMAN; RNA BINDING PROTEIN;

ADULT; ARTICLE; ASTHENOSPERMIA; CELLULAR DISTRIBUTION; CONTROLLED STUDY; COPY NUMBER VARIATION; HAPLOGROUP; HUMAN; HUMAN TISSUE; IMMUNOFLUORESCENCE; MALE; MALE INFERTILITY; MOUSE; NONHUMAN; OLIGOSPERMIA; PATIENT COUNSELING; PHENOTYPE; POLYMERASE CHAIN REACTION; PSEUDOGENE; RISK FACTOR; RNA SPLICING; RNA-BINDING DOMAIN; SPERM; SPERMATOGENESIS; SPERMATOZOON MOTILITY; SPERMATOZOON TAIL; TESTIS TISSUE; WESTERN BLOTTING; Y CHROMOSOME HAPLOGROUP; ASIAN CONTINENTAL ANCESTRY GROUP; AZOOSPERMIA; BLOOD; CELL NUCLEUS; CLINICAL TRIAL; FLUORESCENT ANTIBODY TECHNIQUE; GENE CONVERSION; GENE EXPRESSION REGULATION; GENETIC ASSOCIATION STUDY; GENETIC PREDISPOSITION; GENETICS; METABOLISM; MULTICENTER STUDY; NUCLEOCYTOPLASMIC TRANSPORT; PATHOLOGY; SPERMATOZOON; TESTIS;

ACTIVE TRANSPORT, CELL NUCLEUS; ADULT; ASIAN CONTINENTAL ANCESTRY GROUP; ASTHENOZOOSPERMIA; AZOOSPERMIA; CELL NUCLEUS; DNA COPY NUMBER VARIATIONS; FLUORESCENT ANTIBODY TECHNIQUE; GENE CONVERSION; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENETIC ASSOCIATION STUDIES; GENETIC PREDISPOSITION TO DISEASE; HUMANS; MALE; NUCLEAR PROTEINS; RNA, MESSENGER; RNA-BINDING PROTEINS; SEMEN; SPERM MOTILITY; SPERMATOZOA; TESTIS;

EID: 85021789813     PISSN: 02681161     EISSN: 14602350     Source Type: Journal    
DOI: 10.1093/humrep/dex100     Document Type: Article

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