How members of the human gut microbiota overcome the sulfation problem posed by glycosaminoglycans

Proceedings of the National Academy of Sciences of the United States of America

Volumn 114, Issue 27, 2017, Pages 7037-7042

  Cartmell, Alan ^a   Lowe, Elisabeth C ^a   Baslé, Arnaud ^a   Firbank, Susan J ^a   Ndeh, Didier A ^a   Murray, Heath ^a   Terrapon, Nicolas ^b   Lombard, Vincent ^b   Henrissat, Bernard ^b,c,d   Turnbull, Jeremy E ^e   Czjzek, Mirjam ^f,g   Gilbert, Harry J ^a   Bolam, David N ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b AIX MARSEILLE UNIVERSITY   (France)

^c CEMAGREF   (France)

^d KING ABDULAZIZ UNIVERSITY   (Saudi Arabia)

^e UNIVERSITY OF LIVERPOOL   (United Kingdom)

^f SORBONNE UNIVERSITÉ   (France)

^g STATION BIOLOGIQUE DE ROSCOFF   (France)

Author keywords

Bacteroides thetaiotaomicron; Glycosaminoglycan degradation; Heparan sulfate; Heparin; Human gut microbiota

Indexed keywords

ENZYME; GLUCOSAMINE; GLUCURONIC ACID; GLYCOSAMINOGLYCAN; IDURONIC ACID; LYASE; PROTEINASE K; SULFATASE; CARBOHYDRATE; HEPARAN SULFATE; HEPARIN; OLIGOSACCHARIDE; POLYSACCHARIDE; POLYSACCHARIDE LYASE; SULFUR;

ARTICLE; BACTEROIDES OVATUS; BACTEROIDES THETAIOTAOMICRON; BINDING SITE; CARBOXY TERMINAL SEQUENCE; CONFORMATIONAL TRANSITION; CRYSTAL STRUCTURE; HUMAN; IMMUNOFLUORESCENCE; IMMUNOPRECIPITATION; INTESTINE FLORA; ISOTHERMAL TITRATION CALORIMETRY; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; SULFATION; UPREGULATION; WESTERN BLOTTING; X RAY CRYSTALLOGRAPHY; BACTEROIDES; CALORIMETRY; CARBOHYDRATE DIET; CATALYSIS; CHEMISTRY; CYTOPLASM; ENZYMOLOGY; FLUORESCENCE MICROSCOPY; GENETICS; MUTATION;

BACTEROIDES; CALORIMETRY; CARBOHYDRATES; CATALYSIS; CRYSTALLOGRAPHY, X-RAY; CYTOPLASM; DIETARY CARBOHYDRATES; GASTROINTESTINAL MICROBIOME; GLYCOSAMINOGLYCANS; HEPARIN; HEPARITIN SULFATE; HUMANS; MICROSCOPY, FLUORESCENCE; MUTATION; OLIGOSACCHARIDES; POLYSACCHARIDE-LYASES; POLYSACCHARIDES; SULFATASES; SULFUR;

EID: 85021750830     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1704367114     Document Type: Article

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