메뉴 건너뛰기




Volumn 24, Issue 11, 2017, Pages 936-943

Real-world effectiveness of ombitasvir/paritaprevir/ritonavir±dasabuvir±ribavirin in patients with hepatitis C virus genotype 1 or 4 infection: A meta-analysis

Author keywords

2D; 3D; HCV genotypes 1 and 4; hepatitis C; meta analysis; real world effectiveness

Indexed keywords

ANTIVIRUS AGENT; DASABUVIR PLUS OMBITASVIR PLUS PARITAPREVIR PLUS RIBAVIRIN PLUS RITONAVIR; UNCLASSIFIED DRUG; ABT-267; ABT-450; ANILIDE; CARBAMIC ACID DERIVATIVE; MACROCYCLIC COMPOUND; RIBAVIRIN; RITONAVIR;

EID: 85021744504     PISSN: 13520504     EISSN: 13652893     Source Type: Journal    
DOI: 10.1111/jvh.12722     Document Type: Article
Times cited : (51)

References (50)
  • 1
    • 84921060015 scopus 로고    scopus 로고
    • Global distribution and prevalence of hepatitis C virus genotypes
    • Messina JP, Humphreys I, Flaxman A, et al. Global distribution and prevalence of hepatitis C virus genotypes. Hepatology. 2015;61:77-87.
    • (2015) Hepatology , vol.61 , pp. 77-87
    • Messina, J.P.1    Humphreys, I.2    Flaxman, A.3
  • 2
    • 84914150658 scopus 로고    scopus 로고
    • Global epidemiology and genotype distribution of the hepatitis C virus infection
    • Gower E, Estes C, Blach S, Razavi-Shearer K, Razavi H. Global epidemiology and genotype distribution of the hepatitis C virus infection. J Hepatol. 2014;61(1 Suppl):S45-S57.
    • (2014) J Hepatol , vol.61 , Issue.1 , pp. S45-S57
    • Gower, E.1    Estes, C.2    Blach, S.3    Razavi-Shearer, K.4    Razavi, H.5
  • 4
    • 33748114343 scopus 로고    scopus 로고
    • The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide
    • Perz JF, Armstrong GL, Farrington LA, Hutin YJ, Bell BP. The contributions of hepatitis B virus and hepatitis C virus infections to cirrhosis and primary liver cancer worldwide. J Hepatol. 2006;45:529-538.
    • (2006) J Hepatol , vol.45 , pp. 529-538
    • Perz, J.F.1    Armstrong, G.L.2    Farrington, L.A.3    Hutin, Y.J.4    Bell, B.P.5
  • 5
    • 84857797505 scopus 로고    scopus 로고
    • Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study
    • Bezemer G, Van Gool AR, Verheij-Hart E, et al. Long-term effects of treatment and response in patients with chronic hepatitis C on quality of life. An international, multicenter, randomized, controlled study. BMC Gastroenterol. 2012;12:11.
    • (2012) BMC Gastroenterol , vol.12 , pp. 11
    • Bezemer, G.1    Van Gool, A.R.2    Verheij-Hart, E.3
  • 7
    • 85013413481 scopus 로고    scopus 로고
    • Reversion of disease manifestations after HCV eradication
    • van der Meer AJ, Berenguer M. Reversion of disease manifestations after HCV eradication. J Hepatol. 2016;65(1 Suppl):S95-S108.
    • (2016) J Hepatol , vol.65 , Issue.1 , pp. S95-S108
    • van der Meer, A.J.1    Berenguer, M.2
  • 8
    • 84934823081 scopus 로고    scopus 로고
    • From non-A, non-B hepatitis to hepatitis C virus cure
    • Pawlotsky JM, Feld JJ, Zeuzem S, Hoofnagle JH. From non-A, non-B hepatitis to hepatitis C virus cure. J Hepatol. 2015;62(1 Suppl):S87-S99.
    • (2015) J Hepatol , vol.62 , Issue.1 , pp. S87-S99
    • Pawlotsky, J.M.1    Feld, J.J.2    Zeuzem, S.3    Hoofnagle, J.H.4
  • 9
    • 84901044326 scopus 로고    scopus 로고
    • ABT-450/r–ombitasvir and dasabuvir with or without ribavirin for HCV
    • Ferenci P, Bernstein D, Lalezari J, et al. ABT-450/r–ombitasvir and dasabuvir with or without ribavirin for HCV. N Engl J Med. 2014;370:1983-1992.
    • (2014) N Engl J Med , vol.370 , pp. 1983-1992
    • Ferenci, P.1    Bernstein, D.2    Lalezari, J.3
  • 10
    • 84901036125 scopus 로고    scopus 로고
    • ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis
    • Poordad F, Hezode C, Trinh R, et al. ABT-450/r-ombitasvir and dasabuvir with ribavirin for hepatitis C with cirrhosis. N Engl J Med. 2014;370:1973-1982.
    • (2014) N Engl J Med , vol.370 , pp. 1973-1982
    • Poordad, F.1    Hezode, C.2    Trinh, R.3
  • 11
    • 84925428093 scopus 로고    scopus 로고
    • Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial
    • Sulkowski MS, Eron JJ, Wyles D, et al. Ombitasvir, paritaprevir co-dosed with ritonavir, dasabuvir, and ribavirin for hepatitis C in patients co-infected with HIV-1: a randomized trial. JAMA. 2015;313:1223-1231.
    • (2015) JAMA , vol.313 , pp. 1223-1231
    • Sulkowski, M.S.1    Eron, J.J.2    Wyles, D.3
  • 12
    • 84899106124 scopus 로고    scopus 로고
    • Retreatment of HCV with ABT-450/r–ombitasvir and dasabuvir with ribavirin
    • Zeuzem S, Jacobson IM, Baykal T, et al. Retreatment of HCV with ABT-450/r–ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014;370:1604-1614.
    • (2014) N Engl J Med , vol.370 , pp. 1604-1614
    • Zeuzem, S.1    Jacobson, I.M.2    Baykal, T.3
  • 13
    • 84975809833 scopus 로고    scopus 로고
    • 99.7% sustained virologic response rate in 369 HCV genotype 1b-infected patients treated with label-recommended regimen of ombitasvir/paritaprevir/r and dasabuvir with or without ribavirin
    • Jacobson IM, Dufour JF, Wedemeyer H, et al. 99.7% sustained virologic response rate in 369 HCV genotype 1b-infected patients treated with label-recommended regimen of ombitasvir/paritaprevir/r and dasabuvir with or without ribavirin. Am J Gastroenterol. 2015;110(S1):S850-S851.
    • (2015) Am J Gastroenterol , vol.110 , Issue.S1 , pp. S850-S851
    • Jacobson, I.M.1    Dufour, J.F.2    Wedemeyer, H.3
  • 14
    • 84975827810 scopus 로고    scopus 로고
    • Sustained virologic response rate of 96% in HCV genotype 1a-infected patients treated with ombitasvir/paritaprevir/r and dasabuvir with ribavirin
    • Rustgi V, Wedemeyer H, Pockros P, et al. Sustained virologic response rate of 96% in HCV genotype 1a-infected patients treated with ombitasvir/paritaprevir/r and dasabuvir with ribavirin. Am J Gastroenterol. 2015;110(S1):S862.
    • (2015) Am J Gastroenterol , vol.110 , Issue.1 , pp. 862
    • Rustgi, V.1    Wedemeyer, H.2    Pockros, P.3
  • 15
    • 84954286001 scopus 로고    scopus 로고
    • Sustained virologic response of 100% in HCV genotype 1b patients with cirrhosis receiving ombitasvir/paritaprevir/r and dasabuvir for 12 weeks
    • Feld JJ, Moreno C, Trinh R, et al. Sustained virologic response of 100% in HCV genotype 1b patients with cirrhosis receiving ombitasvir/paritaprevir/r and dasabuvir for 12 weeks. J Hepatol. 2016;64:301-307.
    • (2016) J Hepatol , vol.64 , pp. 301-307
    • Feld, J.J.1    Moreno, C.2    Trinh, R.3
  • 16
    • 84980728956 scopus 로고    scopus 로고
    • Ombitasvir, paritaprevir, and ritonavir plus ribavirin in adults with hepatitis C virus genotype 4 infection and cirrhosis (AGATE-I): a multicentre, phase 3, randomised open-label trial
    • Asselah T, Hézode C, Qaqish RB, et al. Ombitasvir, paritaprevir, and ritonavir plus ribavirin in adults with hepatitis C virus genotype 4 infection and cirrhosis (AGATE-I): a multicentre, phase 3, randomised open-label trial. Lancet Gastroenterol Hepatol. 2016;1:25-35.
    • (2016) Lancet Gastroenterol Hepatol , vol.1 , pp. 25-35
    • Asselah, T.1    Hézode, C.2    Qaqish, R.B.3
  • 17
    • 84931569160 scopus 로고    scopus 로고
    • Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial
    • Hezode C, Asselah T, Reddy KR, et al. Ombitasvir plus paritaprevir plus ritonavir with or without ribavirin in treatment-naive and treatment-experienced patients with genotype 4 chronic hepatitis C virus infection (PEARL-I): a randomised, open-label trial. Lancet. 2015;385:2502-2509.
    • (2015) Lancet , vol.385 , pp. 2502-2509
    • Hezode, C.1    Asselah, T.2    Reddy, K.R.3
  • 18
    • 84996527481 scopus 로고    scopus 로고
    • Ombitasvir, paritaprevir, and ritonavir plus ribavirin for chronic hepatitis C virus genotype 4 infection in Egyptian patients with or without compensated cirrhosis (AGATE-II): a multicentre, phase 3, partly randomised open-label trial
    • Waked I, Shiha G, Qaqish RB, et al. Ombitasvir, paritaprevir, and ritonavir plus ribavirin for chronic hepatitis C virus genotype 4 infection in Egyptian patients with or without compensated cirrhosis (AGATE-II): a multicentre, phase 3, partly randomised open-label trial. Lancet Gastroenterol Hepatol. 2016;1:36-44.
    • (2016) Lancet Gastroenterol Hepatol , vol.1 , pp. 36-44
    • Waked, I.1    Shiha, G.2    Qaqish, R.B.3
  • 19
    • 84928999361 scopus 로고    scopus 로고
    • Impact of all oral anti-hepatitis C virus therapy: a meta-analysis
    • Bansal S, Singal AK, McGuire BM, Anand BS. Impact of all oral anti-hepatitis C virus therapy: a meta-analysis. World J Hepatol. 2015;7:806-813.
    • (2015) World J Hepatol , vol.7 , pp. 806-813
    • Bansal, S.1    Singal, A.K.2    McGuire, B.M.3    Anand, B.S.4
  • 20
    • 0035811625 scopus 로고    scopus 로고
    • Hepatitis C virus infection
    • Lauer GM, Walker BD. Hepatitis C virus infection. N Engl J Med. 2001;345:41-52.
    • (2001) N Engl J Med , vol.345 , pp. 41-52
    • Lauer, G.M.1    Walker, B.D.2
  • 21
    • 84947554940 scopus 로고    scopus 로고
    • Hepatitis C virus treatment in the real world: optimising treatment and access to therapies
    • Zoulim F, Liang TJ, Gerbes AL, et al. Hepatitis C virus treatment in the real world: optimising treatment and access to therapies. Gut. 2015;64:1824-1833.
    • (2015) Gut , vol.64 , pp. 1824-1833
    • Zoulim, F.1    Liang, T.J.2    Gerbes, A.L.3
  • 22
    • 84898669547 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection
    • Afdhal N, Zeuzem S, Kwo P, et al. Ledipasvir and sofosbuvir for untreated HCV genotype 1 infection. N Engl J Med. 2014;370:1889-1898.
    • (2014) N Engl J Med , vol.370 , pp. 1889-1898
    • Afdhal, N.1    Zeuzem, S.2    Kwo, P.3
  • 23
    • 84900326091 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis
    • Kowdley KV, Gordon SC, Reddy KR, et al. Ledipasvir and sofosbuvir for 8 or 12 weeks for chronic HCV without cirrhosis. N Engl J Med. 2014;370:1879-1888.
    • (2014) N Engl J Med , vol.370 , pp. 1879-1888
    • Kowdley, K.V.1    Gordon, S.C.2    Reddy, K.R.3
  • 24
    • 85013959995 scopus 로고    scopus 로고
    • Real-world outcomes of ledipasvir/sofosbuvir in treatment-naive patients with hepatitis C
    • Younossi ZM, Park H, Gordon SC, et al. Real-world outcomes of ledipasvir/sofosbuvir in treatment-naive patients with hepatitis C. Am J Manag Care. 2016;22(6 Spec No.):SP205-SP211.
    • (2016) Am J Manag Care , vol.22 , Issue.6 Spec , pp. SP205-SP211
    • Younossi, Z.M.1    Park, H.2    Gordon, S.C.3
  • 25
    • 84979072442 scopus 로고    scopus 로고
    • Real world effectiveness of ledipasvir/sofosbuvir in 4365 treatment-naive genotype 1 hepatitis c infected patients
    • Backus LI, Belperio PS, Shahoumian TA, Loomis TP, Mole LA. Real world effectiveness of ledipasvir/sofosbuvir in 4365 treatment-naive genotype 1 hepatitis c infected patients. Hepatology. 2016;64:405-414.
    • (2016) Hepatology , vol.64 , pp. 405-414
    • Backus, L.I.1    Belperio, P.S.2    Shahoumian, T.A.3    Loomis, T.P.4    Mole, L.A.5
  • 27
    • 84994340595 scopus 로고    scopus 로고
    • Treatment of HCV genotype 2 with sofosbuvir and ribavirin results in lower sustained virological response rates in real life than expected from clinical trials
    • Tacke F, Gunther R, Buggisch P, et al. Treatment of HCV genotype 2 with sofosbuvir and ribavirin results in lower sustained virological response rates in real life than expected from clinical trials. Liver Int. 2017;37:205-211.
    • (2017) Liver Int , vol.37 , pp. 205-211
    • Tacke, F.1    Gunther, R.2    Buggisch, P.3
  • 28
    • 84991071701 scopus 로고    scopus 로고
    • Real-world experience with ombitasvir/paritaprevir boosted with ritonavir and possibly combined with dasabuvir and ribavirin in HCV infection
    • Pogorzelska J, Flisiak R. Real-world experience with ombitasvir/paritaprevir boosted with ritonavir and possibly combined with dasabuvir and ribavirin in HCV infection. Clin Exp Hepatol. 2016;2:34-37.
    • (2016) Clin Exp Hepatol , vol.2 , pp. 34-37
    • Pogorzelska, J.1    Flisiak, R.2
  • 29
    • 0000694159 scopus 로고
    • Transformations related to the angular and the square root
    • Freeman M, Tukey J. Transformations related to the angular and the square root. Ann Math Stat. 1950;21:607-611.
    • (1950) Ann Math Stat , vol.21 , pp. 607-611
    • Freeman, M.1    Tukey, J.2
  • 31
    • 0037098199 scopus 로고    scopus 로고
    • Quantifying heterogeneity in a meta-analysis
    • Higgins JP, Thompson SG. Quantifying heterogeneity in a meta-analysis. Stat Med. 2002;21:1539-1558.
    • (2002) Stat Med , vol.21 , pp. 1539-1558
    • Higgins, J.P.1    Thompson, S.G.2
  • 33
    • 84899068302 scopus 로고    scopus 로고
    • Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin
    • Feld JJ, Kowdley KV, Coakley E, et al. Treatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014;370:1594-1603.
    • (2014) N Engl J Med , vol.370 , pp. 1594-1603
    • Feld, J.J.1    Kowdley, K.V.2    Coakley, E.3
  • 34
    • 84899106124 scopus 로고    scopus 로고
    • Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin
    • Zeuzem S, Jacobson IM, Baykal T, et al. Retreatment of HCV with ABT-450/r-ombitasvir and dasabuvir with ribavirin. N Engl J Med. 2014;370:1604-1614.
    • (2014) N Engl J Med , vol.370 , pp. 1604-1614
    • Zeuzem, S.1    Jacobson, I.M.2    Baykal, T.3
  • 35
    • 84922372748 scopus 로고    scopus 로고
    • Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis C virus genotype 1 infection in the AVIATOR study
    • Poordad F, Agarwal K, Younes Z, et al. Low relapse rate leads to high concordance of sustained virologic response (SVR) at 12 weeks with SVR at 24 weeks after treatment with ABT-450/ritonavir, ombitasvir, and dasabuvir plus ribavirin in subjects with chronic hepatitis C virus genotype 1 infection in the AVIATOR study. Clin Infect Dis. 2015;60:608-610.
    • (2015) Clin Infect Dis , vol.60 , pp. 608-610
    • Poordad, F.1    Agarwal, K.2    Younes, Z.3
  • 36
    • 75149151884 scopus 로고    scopus 로고
    • Resistance to direct antiviral agents in patients with hepatitis C virus infection
    • Sarrazin C, Zeuzem S. Resistance to direct antiviral agents in patients with hepatitis C virus infection. Gastroenterology. 2010;138:447-462.
    • (2010) Gastroenterology , vol.138 , pp. 447-462
    • Sarrazin, C.1    Zeuzem, S.2
  • 37
    • 84952883325 scopus 로고    scopus 로고
    • Sofosbuvir and velpatasvir for HCV genotype 1, 2, 4, 5, and 6 infection
    • Feld JJ, Jacobson IM, Hezode C, et al. Sofosbuvir and velpatasvir for HCV genotype 1, 2, 4, 5, and 6 infection. N Engl J Med. 2015;373:2599-2607.
    • (2015) N Engl J Med , vol.373 , pp. 2599-2607
    • Feld, J.J.1    Jacobson, I.M.2    Hezode, C.3
  • 38
    • 84939815619 scopus 로고    scopus 로고
    • Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study
    • Kohli A, Kapoor R, Sims Z, et al. Ledipasvir and sofosbuvir for hepatitis C genotype 4: a proof-of-concept, single-centre, open-label phase 2a cohort study. Lancet Infect Dis. 2015;15:1049-1054.
    • (2015) Lancet Infect Dis , vol.15 , pp. 1049-1054
    • Kohli, A.1    Kapoor, R.2    Sims, Z.3
  • 39
    • 84937064772 scopus 로고    scopus 로고
    • Grazoprevir-Elbasvir combination therapy for treatment-naive cirrhotic and noncirrhotic patients with chronic hepatitis c virus genotype 1, 4, or 6 infection: a randomized trial
    • Zeuzem S, Ghalib R, Reddy KR, et al. Grazoprevir-Elbasvir combination therapy for treatment-naive cirrhotic and noncirrhotic patients with chronic hepatitis c virus genotype 1, 4, or 6 infection: a randomized trial. Ann Intern Med. 2015;163:1-13.
    • (2015) Ann Intern Med , vol.163 , pp. 1-13
    • Zeuzem, S.1    Ghalib, R.2    Reddy, K.R.3
  • 40
    • 77954333413 scopus 로고    scopus 로고
    • Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection
    • Alazawi W, Cunningham M, Dearden J, Foster GR. Systematic review: outcome of compensated cirrhosis due to chronic hepatitis C infection. Aliment Pharmacol Ther. 2010;32:344-355.
    • (2010) Aliment Pharmacol Ther , vol.32 , pp. 344-355
    • Alazawi, W.1    Cunningham, M.2    Dearden, J.3    Foster, G.R.4
  • 41
    • 28844490547 scopus 로고    scopus 로고
    • Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies
    • D'Amico G, Garcia-Tsao G, Pagliaro L. Natural history and prognostic indicators of survival in cirrhosis: a systematic review of 118 studies. J Hepatol. 2006;44:217-231.
    • (2006) J Hepatol , vol.44 , pp. 217-231
    • D'Amico, G.1    Garcia-Tsao, G.2    Pagliaro, L.3
  • 42
    • 84957049564 scopus 로고    scopus 로고
    • Hepatic decompensation during direct-acting antiviral therapy of chronic hepatitis C
    • Hoofnagle JH. Hepatic decompensation during direct-acting antiviral therapy of chronic hepatitis C. J Hepatol. 2016;64:763-765.
    • (2016) J Hepatol , vol.64 , pp. 763-765
    • Hoofnagle, J.H.1
  • 47
    • 84966733521 scopus 로고    scopus 로고
    • Efficacy of direct-acting antiviral combination for patients with hepatitis C virus genotype 1 infection and severe renal impairment or end-stage renal disease
    • Pockros PJ, Reddy KR, Mantry PS, et al. Efficacy of direct-acting antiviral combination for patients with hepatitis C virus genotype 1 infection and severe renal impairment or end-stage renal disease. Gastroenterology. 2016;150:1590-1598.
    • (2016) Gastroenterology , vol.150 , pp. 1590-1598
    • Pockros, P.J.1    Reddy, K.R.2    Mantry, P.S.3
  • 48
    • 33947683421 scopus 로고    scopus 로고
    • Relationship between glomerular filtration rate and the prevalence of metabolic abnormalities: results from the Third National Health and Nutrition Examination Survey (NHANES III)
    • Clase CM, Kiberd BA, Garg AX. Relationship between glomerular filtration rate and the prevalence of metabolic abnormalities: results from the Third National Health and Nutrition Examination Survey (NHANES III). Nephron Clin Pract. 2007;105:c178-c184.
    • (2007) Nephron Clin Pract , vol.105 , pp. c178-c184
    • Clase, C.M.1    Kiberd, B.A.2    Garg, A.X.3
  • 49
    • 84894273048 scopus 로고    scopus 로고
    • Prevalence of anemia in chronic kidney disease in the United States
    • Stauffer ME, Fan T. Prevalence of anemia in chronic kidney disease in the United States. PLoS One. 2014;9:e84943.
    • (2014) PLoS One , vol.9
    • Stauffer, M.E.1    Fan, T.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.