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Volumn 8, Issue 6, 2017, Pages 1246-1254
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Pyrazolo[3,4-: D] pyrimidines as sigma-1 receptor ligands for the treatment of pain. Part 2: Introduction of cyclic substituents in position 4
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Author keywords
[No Author keywords available]
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Indexed keywords
1 [1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]PYRROLIDIN 2 ONE;
1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 AMINE;
2 [1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDIN 4 YL]OXAZOLE;
4 (1 METHYL 1H PYRAZOL 5 YL) 1 [2 (PIPERIDIN 1 YL) ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
4 (1H IMIDAZOL 1 YL) 1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
4 (2,5 DIMETHYL 1H PYRROL 1 YL) 1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
4 (4,4 DIFLUOROPIPERIDIN 1 YL) 1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
4 CHLORO 1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
4 PHENYL 1 [2 (PIPERIDIN 1 YL)ETHYL] 1H PYRAZOLO[3,4 D]PYRIMIDINE;
LIGAND;
PYRAZOLO[3,4 D]PYRIMIDINE DERIVATIVE;
SIGMA 1 OPIATE RECEPTOR;
UNCLASSIFIED DRUG;
ANIMAL EXPERIMENT;
ANIMAL MODEL;
ANTINOCICEPTION;
ARTICLE;
CONTROLLED STUDY;
DISEASE MODEL;
DRUG SCREENING;
DRUG STRUCTURE;
DRUG SYNTHESIS;
LIPOPHILICITY;
MOUSE;
NONHUMAN;
PAIN;
PHYSICAL CHEMISTRY;
PRIORITY JOURNAL;
STRUCTURE ACTIVITY RELATION;
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EID: 85021665586
PISSN: 20402503
EISSN: 20402511
Source Type: Journal
DOI: 10.1039/c7md00078b Document Type: Article |
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Times cited : (4)
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References (25)
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