Mechanism of action for rTMS: A working hypothesis based on animal studies

Frontiers in Physiology

Volumn 8, Issue JUN, 2017, Pages

  Rajan, Thangavelu Soundara ^a   Ghilardi, Maria F M ^b,c   Wang, H Y ^b   Mazzon, Emanuela ^a   Bramanti, Placido ^a   Restivo, Domenico ^d   Quartarone, Angelo ^a,e  

^a IRCCS CENTRO NEUROLESI BONINO PULEJO   (Italy)

^b CITY UNIVERSITY OF NEW YORK MEDICAL SCHOOL   (United States)

^c NEW YORK UNIVERSITY MEDICAL CENTER   (United States)

^d GARIBALDI HOSPITAL   (Italy)

^e UNIVERSITY OF MESSINA   (Italy)

Author keywords

BDNF TrKB signaling; Long term potentiation; Neuroprotection; NMDA; TMS

Indexed keywords

AMPA RECEPTOR; BRAIN DERIVED NEUROTROPHIC FACTOR; BRAIN DERIVED NEUROTROPHIC FACTOR RECEPTOR; GLUTAMATE RECEPTOR 1; GLUTAMIC ACID; KETAMINE; N METHYL DEXTRO ASPARTIC ACID; NEUROTROPHIC FACTOR;

BINDING AFFINITY; CORTICAL EXCITABILITY; GENE INDUCTION; HUMAN; IMMEDIATE EARLY GENE; INFLAMMATION; LONG TERM DEPRESSION; LONG TERM POTENTIATION; MEMBRANE POTENTIAL; MOTOR EVOKED POTENTIAL; NERVE CELL PLASTICITY; NEUROENDOCRINE SYSTEM; NEUROMODULATION; NEUROPROTECTION; NEUROTRANSMISSION; NONHUMAN; OXIDATIVE STRESS; PREFRONTAL CORTEX; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; REPETITIVE TRANSCRANIAL MAGNETIC STIMULATION; RODENT; SHORT SURVEY; SIGNAL TRANSDUCTION; STEADY STATE;

EID: 85021630273     PISSN: None     EISSN: 1664042X     Source Type: Journal    
DOI: 10.3389/fphys.2017.00457     Document Type: Short Survey

References (14)

1. Banerjee, J., Sorrell, M. E., Celnik, P. A., and Pelled, G. (2017). Immediate effects of repetitive magnetic stimulation on single cortical pyramidal neurons. PLoS ONE 12:e0170528. doi: 10.1371/journal.pone.0170528
2. Chervyakov, A. V., Chernyavsky, A. Y., Sinitsyn, D. O., and Piradov, M. A. (2015). Possible mechanisms underlying the therapeutic effects of transcranial magnetic stimulation. Front. Hum. Neurosci. 9:303. doi: 10.3389/fnhum.2015.00303
3. Cirillo, G., Di Pino, G., Capone, F., Ranieri, F., Florio, L., Todisco, V., et al. (2017). Neurobiological after-effects of non-invasive brain stimulation. Brain Stimul. 10, 1-18. doi: 10.1016/j.brs.2016.11.009
4. Di Lazzaro, V., Oliviero, A., Profice, P., Pennisi, M. A., Pilato, F., Zito, G., et al. (2003). Ketamine increases human motor cortex excitability to transcranial magnetic stimulation. J. Physiol. (Lond). 547, 485-496. doi: 10.1113/jphysiol.2002.030486
5. Di Lazzaro, V., Restuccia, D., Oliviero, A., Profice, P., Ferrara, L., Insola, A., et al. (1998). Effects of voluntary contraction on descending volleys evoked by transcranial stimulation in conscious humans. J. Physiol. 508 (Pt 2), 625-633. doi: 10.1111/j.1469-7793.1998.625bq.x
6. Fleming, J. J., and England, P. M. (2010). AMPA receptors and synaptic plasticity: a chemist's perspective. Nat. Chem. Biol. 6, 89-97. doi: 10.1038/nchembio.298
7. Gersner, R., Kravetz, E., Feil, J., Pell, G., and Zangen, A. (2011). Long-term effects of repetitive transcranial magnetic stimulation on markers for neuroplasticity: differential outcomes in anesthetized and awake animals. J. Neurosci. 31, 7521-7526. doi: 10.1523/JNEUROSCI.6751-10.2011
8. Malenka, R. C., and Bear, M. F. (2004). LTP and LTD: an embarrassment of riches. Neuron 44, 5-21. doi: 10.1016/j.neuron.2004.09.012
9. Quartarone, A., Siebner, H. R., and Rothwell, J. C. (2006). Task-specific hand dystonia: can too much plasticity be bad for you? Trends Neurosci. 29, 192-199. doi: 10.1016/j.tins.2006.02.007
10. Schwenkreis, P., Witscher, K., Pleger, B., Malin, J.-P., and Tegenthoff, M. (2005). The NMDA antagonist memantine affects training induced motor cortex plasticity-a study using transcranial magnetic stimulation. BMC Neurosci. 6:35. doi: 10.1186/1471-2202-6-35
11. Vlachos, A., Muller-Dahlhaus, F., Rosskopp, J., Lenz, M., Ziemann, U., and Deller, T. (2012). Repetitive magnetic stimulation induces functional and structural plasticity of excitatory postsynapses in mouse organotypic hippocampal slice cultures. J. Neurosci. 32, 17514-17523. doi: 10.1523/JNEUROSCI.0409-12.2012
12. Wang, H.-Y., Crupi, D., Liu, J., Stucky, A., Cruciata, G., Di Rocco, A., et al. (2011). Repetitive transcranial magnetic stimulation enhances BDNF-TrkB signaling in both brain and lymphocyte. J. Neurosci. 31, 11044-11054. doi: 10.1523/JNEUROSCI.2125-11.2011
13. 2+channels: a single molecular switch for long-term potentiation/long-term depression-like plasticity and activity-dependent metaplasticity in humans. J. Neurosci. 30, 6197-6204. doi: 10.1523/JNEUROSCI.4673-09.2010
14. Ziemann, U., Paulus, W., Nitsche, M. A., Pascual-Leone, A., Byblow, W. D., Berardelli, A., et al. (2008). Consensus: motor cortex plasticity protocols. Brain Stimul. 1, 164-182. doi: 10.1016/j.brs.2008.06.006