Ketamine increases human motor cortex excitability to transcranial magnetic stimulation

Journal of Physiology

Volumn 547, Issue 2, 2003, Pages 485-496

  Di Lazzaro, V ^a   Oliviero, A ^a   Profice, P ^a   Pennisi, M A ^a   Pilato, F ^a   Zito, G ^a   Dileone, M ^a   Nicoletti, R ^a   Pasqualetti, P ^b   Tonali, P A ^c  

^a CATHOLIC UNIVERSITY   (Italy)

^b FATEBENEFRATELLI HOSPITAL   (Italy)

^c CASA SOLLIEVO DELLA SOFFERENZA HOSPITAL   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA AMINO 3 HYDROXY 5 METHYL 4 ISOXAZOLEPROPIONIC ACID; GLUTAMIC ACID; KETAMINE; N METHYL DEXTRO ASPARTIC ACID RECEPTOR; N METHYL DEXTRO ASPARTIC ACID RECEPTOR BLOCKING AGENT;

ADULT; BRAIN DEPTH STIMULATION; CENTRAL NERVOUS SYSTEM; CONTROLLED STUDY; DOSE RESPONSE; DRUG EFFECT; ELECTROMYOGRAM; ELECTROSTIMULATION; EVOKED RESPONSE; FREQUENCY ANALYSIS; HUMAN; HUMAN EXPERIMENT; MOTOR CORTEX; NERVE CELL MEMBRANE POTENTIAL; NERVE CELL MEMBRANE STEADY POTENTIAL; NERVE CELL NETWORK; NORMAL HUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PYRAMIDAL NERVE CELL; REVIEW; SIGNAL TRANSDUCTION; TRANSCRANIAL MAGNETIC STIMULATION; ACTIVE MOTOR THRESHOLD; ANESTHESIA MECHANISM; ARTICLE; DRUG DOSE COMPARISON; GLUTAMATERGIC TRANSMISSION; NERVE CELL EXCITABILITY; NERVOUS SYSTEM PARAMETERS; NEUROTRANSMISSION; RESTING MOTOR THRESHOLD;

ADULT; DIFFERENTIAL THRESHOLD; DOSE-RESPONSE RELATIONSHIP, DRUG; ELECTRIC STIMULATION; ELECTROMYOGRAPHY; EXCITATORY AMINO ACID ANTAGONISTS; FINGERS; HUMANS; KETAMINE; MOTOR CORTEX; MUSCLE, SKELETAL; NEURAL INHIBITION; REACTION TIME; TRANSCRANIAL MAGNETIC STIMULATION;

EID: 0037337058     PISSN: 00223751     EISSN: None     Source Type: Journal    
DOI: 10.1113/jphysiol.2002.030486     Document Type: Review

References (39)

1. Ali AB, Rossier J, Staiger JF & Audinat E (2001). Kainate receptors regulate unitary IPSCs elicited in pyramidal cells by fast-spiking interneurons in the neocortex. J Neurosci 21, 2992-2999.
2. Anis NA, Berry SC, Burton NR & Lodge D (1983). The dissociative anaesthetics, ketamine and phenyclidine, selectively reduce excitation of central mammalian neurones by N-methyl aspartate. B J Pharmacol 79, 565-575.
3. B-mediated inhibition of rat hippocampal pyramidal neurons in vitro. Neuroscience 68, 637-643.
4. Bowyer JF, Albertson TE, Winters WD & Baselt RC (1983). Ketamine-induced changes in kindled amygdaloid seizures. Neuropharmacology 22, 887-894.
5. Bustos G, Abarca J, Forray MI, Gysling K, Bradberry CW & Roth RH (1992). Regulation of excitatory amino acid release by N-methyl-D-aspartate receptors in rat striatum: in vivo microdialysis studies. Brain Res 585, 105-115.
6. Calvin WH & Schwindt PC (1972). Steps in the production of motoneuron spikes during rhythmic firing. J Neurophysiol 35, 297-310.
7. Collingridge GL, Herron CE & Lester RA (1988a). Frequency-dependent N-methyl-D-aspartate receptor-mediated synaptic transmission in rat hippocampus. J Physiol 399, 301-312.
8. Collingridge GL, Herron CE & Lester RA (1988b). Synaptic activation of N-methyl-D-aspartate receptors in the Schaffer collateral-commissural pathway of rat hippocampus. J Physiol 399, 283-300.
9. Conti F & Weinberg RJ (1999). Shaping excitation at glutamatergic synapses. Trends Neurosci 22, 451-458.
10. Di Lazzaro V, Oliviero A, Meglio M, Cioni B, Tamburrini G, Tonali P & Rothwell JC (2000). Direct demonstration of the effect of lorazepam on the excitability of the human motor cortex. Clin Neurophysiol 111, 794-799.
11. Di Lazzaro V, Oliviero A, Profice P, Insola A, Mazzone P, Tonali P & Rothwell JC (1999a). Effects of voluntary contraction on descending volleys evoked by transcranial electrical stimulation over the motor cortex hand area in conscious humans. Exp Brain Res 124, 525-528.
12. Di Lazzaro V, Oliviero A, Profice P, Saturno E, Pilato F, Insola A, Mazzone P, Tonali P & Rothwell JC (1998a). Comparison of descending volleys evoked by transcranial magnetic and electric stimulation in conscious humans. Electroenceph Clin Neurophysiol 109, 397-401.
13. Di Lazzaro V, Restuccia D, Oliviero A, Profice P, Ferrara L, Insola A, Mazzone P, Tonali P & Rothwell JC (1998b). Magnetic transcranial stimulation at intensities below active motor threshold activates intracortical inhibitory circuits. Exp Brain Res 119, 265-268.
14. Di Lazzaro V, Restuccia D, Oliviero A, Profice P, Ferrara L, Insola A, Mazzone P, Tonali P & Rothwell JC (1998c). Effects of voluntary contraction on descending volleys evoked by transcranial stimulation in conscious humans. J Physiol 508, 625-633.
15. Di Lazzaro V, Rothwell JC, Oliviero A, Profice P, Insola A. Mazzone P & Tonali P (1999b). Intracortical origin of the short latency facilitation produced by pairs of threshold magnetic stimuli applied to human motor cortex. Exp Brain Res 129, 494-499.
16. Ferrer-Allado T, Brechner VL, Dymond A, Cozen H & Crandall P (1973). Ketamine-induced electroconvulsive phenomena in the human limbic and thalamic regions. Anesthesiology; 38, 333-344.
17. Folstein MF, Folstein SE & MacHugh PR (1975). 'Mini-mental state'. A practical method for grading the cognitive state of patients for the clinician. J Psychiatr Res 12, 189-198.
18. Ghoneim MM, Hinrichs JV, Mewaldt SP & Petersen RC (1985). Ketamine: behavioral effects of subanesthetic doses. J Clin Psychopharmacol 5, 70-77.
19. Harrison NL & Simmonds MA (1985). Quantitative studies on some antagonists of N-methyl-D-aspartate in slices of rat cerebral cortex. J Pharmacol 84, 381-391.
20. Irifune M, Shimizu T, Nomoto M & Fukuda T (1992). Ketamine-induced anesthesia involves N-methyl-D-aspartate receptor-channel complex in mice. Brain Res 596, 1-9.
21. Kernell D (1965). The limits of firing frequency in cat lumbosacral motoneurones possessing different time course of afterhyperpolarization. Acta Physiol Scand 65, 87-100.
22. Krystal JH, Karper LP, Seibyl JP, Freeman GK, Delaney R, Bremner JD, Heninger GR, Bowers MB & Charney DS (1994). Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry 51, 199-214.
23. Kujirai T, Caramia MD, Rothwell JC, Day BL, Thompson PD, Ferbert A, Wroe S, Asselman P & Marsden CD (1993). Corticocortical inhibition in human motor cortex. J Physiol 471, 501-519.
24. Liu J & Moghaddam B (1995). Regulation of glutamate efflux by excitatory amino acid receptors: evidence for tonic inhibitory and phasic excitatory regulation. J Pharmacol Exp Ther 274, 1209-1215.
25. MacDonald JF, Miljkovic Z & Pennefather P (1987). Use-dependent block of excitatory amino acid currents in cultured neurons by ketamine. J Neurophysiol 58, 251-266.
26. Miller RD (2000). Non-barbiturate intravenous anesthetics. In Anesthesia, 5th edn, chap. 9, ed. Miller RD, Reves JG, Roizen MF, Savarese JJ, Cucchiara RF & Ross A, pp. 228-272. Churchill Livingstone, Philadelphia.
27. Moghaddam B, Adams B, Verma A & Daly D (1997). Activation of glutamatergic neurotransmission by ketamine: a novel step in the pathway from NMDA receptor blockade to dopaminergic and cognitive disruptions associated with the prefrontal cortex. J Neurosci 17, 2921-2927.
28. Overall JE & Gorham DR (1962). Brief psychiatric rating scale. Psychol Rep 10, 799-812.
29. Priesol AJ, Jones GE, Tomlinson RD & Broussard DM (2000). Frequency-dependent effects of glutamate antagonists on the vestibulo-ocular reflex of the cat. Brain Res 857, 252-264.
30. Ridding MC & Rothwell JC (1997). Stimulus/response curves as a method of measuring motor cortical excitability in man. Electroenceph Clin Neurophysiol 105, 340-344.
31. Riker RR, Picard JT & Fraser GL (1999). Prospective evaluation of the Sedation-Agitation Scale for adult critically ill patients. Crit Care Med 27, 1325-1329.
32. Sanger TD, Garg RR & Chen R (2001). Interaction between two different inhibitory systems in the human motor cortex. J Physiol 530, 307-317.
33. Schafer M, Biesecker JC, Schulze-Bonhage A & Ferbert A (1997). Transcranial magnetic double stimulation: influence of the intensity of the conditioning stimulus. Electroenceph Clin Neurophysiol 105, 462-469.
34. Thomson AM, West DC & Lodge D. (1985). An N-methyl-aspartate receptor-mediated synapse in rat cerebral cortex: a site of action of ketamine? Nature 313, 479-481.
35. Tokimura H, Ridding MC, Tokimura Y, Amassian V & Rothwell JC (1996). Short latency facilitation between pairs of threshold magnetic stimuli applied to human motor cortex. Electroenceph Clin Neurophysiol 101, 263-272.
36. Ziemann U, Lonnecker S, Steinhof BJ & Paulus W (1996a). The effect of lorazepam on the motor cortical excitability in man. Exp Brain Res 109, 127-135.
37. Ziemann U, Lonnecker S, Steinhoff BJ & Paulus W (1996b). Effects of antiepileptic drugs on motor cortex excitability in humans: a transcranial magnetic stimulation study. Ann Neurol 40, 367-378.
38. Ziemann U, Tergau F, Wassermann EM, Wischer S, Hildebrandt J & Paulus W (1998a). Demonstration of facilitatory I-wave interaction in the human motor cortex by paired transcranial magnetic stimulation. J Physiol 511, 181-190.
39. Ziemann U, Tergau F, Wischer S, Hildebrandt J & Paulus W (1998b). Pharmacological control of facilitatory I-wave interaction in the human motor cortex. A paired transcranial magnetic stimulation study. Electroenceph Clin Neurophysiol 109, 321-330.