Changes in remote myocardial tissue after acute myocardial infarction and its relation to cardiac remodeling: A CMR T1 mapping study

PLoS ONE

Volumn 12, Issue 6, 2017, Pages

  Biesbroek, P Stefan ^a,b   Amier, Raquel P ^a   Teunissen, Paul F A ^a   Hofman, Mark B M ^a   Robbers, Lourens F H J ^a   van de Ven, Peter M ^a   Beek, Aernout M ^a   van Rossum, Albert C ^a   van Royen, Niels ^a   Nijveldt, Robin ^a  

^a VU UNIVERSITY MEDICAL CENTER   (Netherlands)

^b INTERUNIVERSITY CARDIOLOGY INSTITUTE OF THE NETHERLANDS   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

C REACTIVE PROTEIN; BIOLOGICAL MARKER; CONTRAST MEDIUM; GADOLINIUM;

ACUTE HEART INFARCTION; ADULT; ARTICLE; CARDIOVASCULAR MAGNETIC RESONANCE; CLINICAL ARTICLE; EXTRACELLULAR SPACE; FEMALE; FOLLOW UP; HEART DILATATION; HEART INFARCTION SIZE; HEART VENTRICLE REMODELING; HUMAN; MALE; MICROVASCULATURE; MIDDLE AGED; NUCLEAR MAGNETIC RESONANCE SCANNER; PERCUTANEOUS CORONARY INTERVENTION; PREDICTIVE VALUE; RELAXATION TIME; TISSUE CHARACTERIZATION; BLOOD; DIAGNOSTIC IMAGING; HEART; MYOCARDIAL INFARCTION; NUCLEAR MAGNETIC RESONANCE IMAGING; PATHOPHYSIOLOGY; PROSPECTIVE STUDY; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME;

BIOMARKERS; CONTRAST MEDIA; EXTRACELLULAR SPACE; FEMALE; FOLLOW-UP STUDIES; GADOLINIUM; HEART; HUMANS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PROSPECTIVE STUDIES; SEVERITY OF ILLNESS INDEX; TREATMENT OUTCOME; VENTRICULAR REMODELING;

EID: 85021270565     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0180115     Document Type: Article

References (36)

1. Betgem RP, de Waard GA, Nijveldt R, Beek AM, Escaned J, van Royen N. Intramyocardial haemorrhage after acute myocardial infarction. Nat Rev Cardiol. 2015; 12(3): 156–67. https://doi.org/10.1038/nrcardio.2014.188 PMID: 25403783.
2. Ruparelia N, Digby JE, Jefferson A, Medway DJ, Neubauer S, Lygate CA, et al. Myocardial infarction causes inflammation and leukocyte recruitment at remote sites in the myocardium and in the renal glo-merulus. Inflammation Research. 2013; 62(5): 515–25. https://doi.org/10.1007/s00011-013-0605-4 PMID: 23471223
3. Lee WW, Marinelli B, van der Laan AM, Sena BF, Gorbatov R, Leuschner F, et al. PET/MRI of Inflammation in Myocardial Infarction. Journal of the American College of Cardiology. 2012; 59(2): 153–63. https://doi.org/10.1016/j.jacc.2011.08.066 PMID: 22222080
4. Ugander M, Bagi PS, Oki AJ, Chen B, Hsu LY, Aletras AH, et al. Myocardial Edema as Detected by Pre-Contrast T1 and T2 CMR Delineates Area at Risk Associated With Acute Myocardial Infarction. Jacc-Cardiovascular Imaging. 2012; 5(6): 596–603. https://doi.org/10.1016/j.jcmg.2012.01.016 PMID: 22698528
5. Ferreira VM, Piechnik SK, Dall’Armellina E, Karamitsos TD, Francis JM, Choudhury RP, et al. Non-contrast T1-mapping detects acute myocardial edema with high diagnostic accuracy: a comparison to T2-weighted cardiovascular magnetic resonance. J Cardiovasc Magn Reson. 2012; 14: 42. https://doi.org/10.1186/1532-429X-14-42 PMID: 22720998
6. Dall’Armellina E, Piechnik SK, Ferreira VM, Si QL, Robson MD, Francis JM, et al. Cardiovascular magnetic resonance by non contrast T1-mapping allows assessment of severity of injury in acute myocardial infarction. J Cardiovasc Magn Reson. 2012; 14: 15. https://doi.org/10.1186/1532-429X-14-15 PMID: 22309452
7. Ambale-Venkatesh B, Lima JA. Cardiac MRI: a central prognostic tool in myocardial fibrosis. Nat Rev Cardiol. 2015; 12(1): 18–29. https://doi.org/10.1038/nrcardio.2014.159 PMID: 25348690
8. Park CH, Choi EY, Kwon HM, Hong BK, Lee BK, Yoon YW, et al. Quantitative T2 mapping for detecting myocardial edema after reperfusion of myocardial infarction: validation and comparison with T2-weighted images. Int J Cardiovasc Imaging. 2013; 29 Suppl 1: 65–72. https://doi.org/10.1007/s10554-013-0256-0 PMID: 23765068
9. Verhaert D, Thavendiranathan P, Giri S, Mihai G, Rajagopalan S, Simonetti OP, et al. Direct T2 quantification of myocardial edema in acute ischemic injury. JACC Cardiovasc Imaging. 2011; 4(3): 269–78. https://doi.org/10.1016/j.jcmg.2010.09.023 PMID: 21414575
10. Carrick D, Haig C, Rauhalammi S, Ahmed N, Mordi I, McEntegart M, et al. Pathophysiology of LV Remodeling in Survivors of STEMI: Inflammation, Remote Myocardium, and Prognosis. JACC Cardiovasc Imaging. 2015. https://doi.org/10.1016/j.jcmg.2015.03.007 PMID: 26093923
11. Bulluck H, Rosmini S, Abdel-Gadir A, White SK, Bhuva AN, Treibel TA, et al. Automated Extracellular Volume Fraction Mapping Provides Insights Into the Pathophysiology of Left Ventricular Remodeling Post-Reperfused ST-Elevation Myocardial Infarction. J Am Heart Assoc. 2016; 5(7). https://doi.org/10.1161/JAHA.116.003555 PMID: 27402229
12. Carberry J, Carrick D, Haig C, Rauhalammi SM, Ahmed N, Mordi I, et al. Remote Zone Extracellular Volume and Left Ventricular Remodeling in Survivors of ST-Elevation Myocardial Infarction. Hypertension. 2016; 68(2): 385–91. https://doi.org/10.1161/HYPERTENSIONAHA.116.07222 PMID: 27354423
13. Puri KS, Suresh KR, Gogtay NJ, Thatte UM. Declaration of Helsinki, 2008: implications for stakeholders in research. J Postgrad Med. 2009; 55(2): 131–4. https://doi.org/10.4103/0022-3859.52846 PMID: 19550060
14. Teunissen PF, de Waard GA, Hollander MR, Robbers LF, Danad I, Biesbroek PS, et al. Doppler-derived intracoronary physiology indices predict the occurrence of microvascular injury and microvascular perfusion deficits after angiographically successful primary percutaneous coronary intervention. Circ Cardiovasc Interv. 2015; 8(3): e001786. https://doi.org/10.1161/CIRCINTERVENTIONS.114.001786 PMID: 25717044
15. Pokorney SD, Rodriguez JF, Ortiz JT, Lee DC, Bonow RO, Wu E. Infarct healing is a dynamic process following acute myocardial infarction. J Cardiovasc Magn Reson. 2012; 14: 62. https://doi.org/10.1186/ 1532-429X-14-62 PMID: 22937750; PubMed Central PMCID: PMC3443460.
16. Stone GW, Maehara A, Lansky AJ, de Bruyne B, Cristea E, Mintz GS, et al. A prospective natural-history study of coronary atherosclerosis. N Engl J Med. 2011; 364(3): 226–35. https://doi.org/10.1056/ NEJMoa1002358 PMID: 21247313.
17. Hirsch A, Nijveldt R, van der Vleuten PA, Tijssen JG, van der Giessen WJ, Tio RA, et al. Intracoronary infusion of mononuclear cells from bone marrow or peripheral blood compared with standard therapy in patients after acute myocardial infarction treated by primary percutaneous coronary intervention: results of the randomized controlled HEBE trial. Eur Heart J. 2011; 32(14): 1736–47. https://doi.org/10.1093/eurheartj/ehq449 PMID: 21148540.
18. Lonborg J, Vejlstrup N, Kelbaek H, Botker HE, Kim WY, Mathiasen AB, et al. Exenatide reduces reperfusion injury in patients with ST-segment elevation myocardial infarction. Eur Heart J. 2012; 33 (12): 1491–9. https://doi.org/10.1093/eurheartj/ehr309 PMID: 21920963.
19. Brouwer WP, Baars EN, Germans T, de BK, Beek AM, van d V, et al. In-vivo T1 cardiovascular magnetic resonance study of diffuse myocardial fibrosis in hypertrophic cardiomyopathy. J Cardiovasc Magn Reson. 2014; 16: 28. https://doi.org/10.1186/1532-429X-16-28 PMID: 24766828
20. Messroghli DR, Greiser A, Frohlich M, Dietz R, Schulz-Menger J. Optimization and validation of a fully-integrated pulse sequence for modified look-locker inversion-recovery (MOLLI) T1 mapping of the heart. J Magn Reson Imaging. 2007; 26(4): 1081–6. https://doi.org/10.1002/jmri.21119 PMID: 17896383
21. Schulz-Menger J, Bluemke DA, Bremerich J, Flamm SD, Fogel MA, Friedrich MG, et al. Standardized image interpretation and post processing in cardiovascular magnetic resonance: Society for Cardiovascular Magnetic Resonance (SCMR) board of trustees task force on standardized post processing. J Cardiovasc Magn Reson. 2013; 15: 35. https://doi.org/10.1186/1532-429X-15-35 PMID: 23634753
22. Flett AS, Hasleton J, Cook C, Hausenloy D, Quarta G, Anti C, et al. Evaluation of Techniques for the Quantification of Myocardial Scar of Differing Etiology Using Cardiac Magnetic Resonance. Jacc-Cardiovascular Imaging. 2011; 4(2): 150–6. https://doi.org/10.1016/j.jcmg.2010.11.015 PMID: 21329899
23. Park YH, Kang SJ, Song JK, Lee EY, Song JM, Kang DH, et al. Prognostic value of longitudinal strain after primary reperfusion therapy in patients with anterior-wall acute myocardial infarction. J Am Soc Echocardiogr. 2008; 21(3): 262–7. https://doi.org/10.1016/j.echo.2007.08.026 PMID: 17904803
24. Piechnik SK, Ferreira VM, Dall’Armellina E, Cochlin LE, Greiser A, Neubauer S, et al. Shortened Modified Look-Locker Inversion recovery (ShMOLLI) for clinical myocardial T1-mapping at 1.5 and 3 T within a 9 heartbeat breathhold. J Cardiovasc Magn Reson. 2010; 12: 69. https://doi.org/10.1186/1532-429X-12-69 PMID: 21092095; PubMed Central PMCID: PMC3001433.
25. Treibel TA, Fontana M, Maestrini V, Castelletti S, Rosmini S, Simpson J, et al. Automatic Measurement of the Myocardial Interstitium: Synthetic Extracellular Volume Quantification Without Hematocrit Sampling. JACC Cardiovasc Imaging. 2016; 9(1): 54–63. https://doi.org/10.1016/j.jcmg.2015.11.008 PMID: 26762875.
26. Williams ES, Kaplan JI, Thatcher F, Zimmerman G, Knoebel SB. Prolongation of proton spin lattice relaxation times in regionally ischemic tissue from dog hearts. J Nucl Med. 1980; 21(5): 449–53. PMID: 7373415.
27. Fernandez-Jimenez R, Sanchez-Gonzalez J, Aguero J, Garcia-Prieto J, Lopez-Martin GJ, Garcia-Ruiz JM, et al. Myocardial edema after ischemia/reperfusion is not stable and follows a bimodal pattern: imaging and histological tissue characterization. J Am Coll Cardiol. 2015; 65(4): 315–23. https://doi.org/10.1016/j.jacc.2014.11.004 PMID: 25460833
28. Ghugre NR, Pop M, Barry J, Connelly KA, Wright GA. Quantitative magnetic resonance imaging can distinguish remodeling mechanisms after acute myocardial infarction based on the severity of ischemic insult. Magn Reson Med. 2013; 70(4): 1095–105. https://doi.org/10.1002/mrm.24531 PMID: 23165643
29. Zia MI, Ghugre NR, Connelly KA, Strauss BH, Sparkes JD, Dick AJ, et al. Characterizing Myocardial Edema and Hemorrhage Using Quantitative T2 and T2*Mapping at Multiple Time Intervals Post ST-Segment Elevation Myocardial Infarction. Circulation-Cardiovascular Imaging. 2012; 5(5): 566–72. https://doi.org/10.1161/CIRCIMAGING.112.973222 PMID: 22744938
30. Goebel J, Seifert I, Nensa F, Schemuth HP, Maderwald S, Quick HH, et al. Can Native T1 Mapping Differentiate between Healthy and Diffuse Diseased Myocardium in Clinical Routine Cardiac MR Imaging? PLoS One. 2016; 11(5): e0155591. https://doi.org/10.1371/journal.pone.0155591 PMID: 27219329
31. Moon JC, Messroghli DR, Kellman P, Piechnik SK, Robson MD, Ugander M, et al. Myocardial T1 mapping and extracellular volume quantification: a Society for Cardiovascular Magnetic Resonance (SCMR) and CMR Working Group of the European Society of Cardiology consensus statement. J Cardiovasc Magn Reson. 2013; 15: 92. https://doi.org/10.1186/1532-429X-15-92 PMID: 24124732
32. Abbate A, Bussani R, Liuzzo G, Biondi-Zoccai GG, Barresi E, Mellone P, et al. Sudden coronary death, fatal acute myocardial infarction and widespread coronary and myocardial inflammation. Heart. 2008; 94(6): 737–42. https://doi.org/10.1136/hrt.2007.115329 PMID: 17698556
33. Cleutjens JP, Verluyten MJ, Smiths JF, Daemen MJ. Collagen remodeling after myocardial infarction in the rat heart. Am J Pathol. 1995; 147(2): 325–38. PMID: 7639329
34. Tsuda T, Gao E, Evangelisti L, Markova D, Ma X, Chu ML. Post-ischemic myocardial fibrosis occurs independent of hemodynamic changes. Cardiovasc Res. 2003; 59(4): 926–33. PMID: 14553832
35. Schelbert EB, Hsu LY, Anderson SA, Mohanty BD, Karim SM, Kellman P, et al. Late gadolinium-enhancement cardiac magnetic resonance identifies postinfarction myocardial fibrosis and the border zone at the near cellular level in ex vivo rat heart. Circ Cardiovasc Imaging. 2010; 3(6): 743–52. https://doi.org/10.1161/CIRCIMAGING.108.835793 PMID: 20847191; PubMed Central PMCID: PMC3398602.
36. Kim RJ, Fieno DS, Parrish TB, Harris K, Chen EL, Simonetti O, et al. Relationship of MRI delayed contrast enhancement to irreversible injury, infarct age, and contractile function. Circulation. 1999; 100 (19): 1992–2002. PMID: 10556226.