Characterizing myocardial edema and hemorrhage using quantitative t2 and t2* mapping at multiple time intervals post ST-segment elevation myocardial infarction

Circulation: Cardiovascular Imaging

Volumn 5, Issue 5, 2012, Pages 566-572

  Zia, Mohammad I ^a,b   Ghugre, Nilesh R ^a   Connelly, Kim A ^c,d   Strauss, Bradley H ^a   Sparkes, John D ^a   Dick, Alexander J ^a   Wright, Graham A ^a  

^a Division of Cardiology   (Canada)

^b TORONTO EAST GENERAL HOSPITAL   (Canada)

^c ST MICHAEL'S HOSPITAL   (Canada)

^d UNIVERSITY OF TORONTO   (Canada)

Author keywords

Edema; Hemorrhage; Magnetic resonance imaging; Myocardial infarction

Indexed keywords

ADULT; AGED; ARTICLE; BLEEDING; FEMALE; HEART EDEMA; HEART MUSCLE BLEEDING; HUMAN; MAJOR CLINICAL STUDY; MALE; MYOCARDIAL EDEMA; NUCLEAR MAGNETIC RESONANCE; PERCUTANEOUS CORONARY INTERVENTION; PRIORITY JOURNAL; PROSPECTIVE STUDY; QUANTITATIVE ANALYSIS; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION;

AGED; ANGIOPLASTY, BALLOON, CORONARY; CHI-SQUARE DISTRIBUTION; EDEMA, CARDIAC; FEASIBILITY STUDIES; FEMALE; HEMORRHAGE; HUMANS; MAGNETIC RESONANCE IMAGING, CINE; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; MYOCARDIUM; ONTARIO; PREDICTIVE VALUE OF TESTS; PROSPECTIVE STUDIES; TIME FACTORS; TREATMENT OUTCOME; VENTRICULAR REMODELING;

EID: 84867147403     PISSN: 19419651     EISSN: 19420080     Source Type: Journal    
DOI: 10.1161/CIRCIMAGING.112.973222     Document Type: Article

References (28)

1. Basso C, Thiene G. The pathophysiology of myocardial reperfusion: a pathologist's perspective. Heart. 2006;92:1559-1562. (Pubitemid 44629154)
2. Fujiwara H, Onodera T, Tanaka M, Fujiwara T, Wu DJ, Kawai C, Hamashima Y. A clinicopathologic study of patients with hemorrhagic myocardial infarction treated with selective coronary thrombolysis with urokinase. Circulation. 1986;73:749-757. (Pubitemid 16081435)
3. Ganame J, Messalli G, Dymarkowski S, Rademakers FE, Desmet W, Van de Werf F, Bogaert J. Impact of myocardial haemorrhage on left ventricular function and remodelling in patients with reperfused acute myocardial infarction. Eur Heart J. 2009;30:1440-1449.
4. Jaffe R, Charron T, Puley G, Dick A, Strauss BH. Microvascular obstruction and the no-reflow phenomenon after percutaneous coronary intervention. Circulation. 2008;117:3152-3156.
5. Jaffe R, Dick A, Strauss BH. Prevention and treatment of microvascular obstruction-related myocardial injury and coronary no-reflow following percutaneous coronary intervention: a systematic approach. JACC Cardiovasc Interv. 2010;3:695-704.
6. Raman SV, Simonetti OP, Winner MW 3rd, Dickerson JA, He X, Mazzaferri EL Jr, Ambrosio G. Cardiac magnetic resonance with edema imaging identifies myocardium at risk and predicts worse outcome in patients with non-ST-segment elevation acute coronary syndrome. J Am Coll Cardiol. 2010;55:2480-2488.
7. Ghugre NR, Ramanan V, Pop M, Yang Y, Barry J, Qiang B, Connelly KA, Dick AJ, Wright GA. Quantitative tracking of edema, hemorrhage, and microvascular obstruction in subacute myocardial infarction in a porcine model by MRI. Magn Reson Med. 2011;66:1129-1141.
8. Mather AN, Fairbairn TA, Artis NJ, Greenwood JP, Plein S. Timing of cardiovascular MR imaging after acute myocardial infarction: effect on estimates of infarct characteristics and prediction of late ventricular remodeling. Radiology. 2011;261:116-126.
9. Rochitte CE, Lima JA, Bluemke DA, Reeder SB, McVeigh ER, Furuta T, Becker LC, Melin JA. Magnitude and time course of microvascular obstruction and tissue injury after acute myocardial infarction. Circulation. 1998;98:1006-1014. (Pubitemid 28446654)
10. Antman EM, Anbe DT, Armstrong PW, Bates ER, Green LA, Hand M, Hochman JS, Krumholz HM, Kushner FG, Lamas GA, Mullany CJ, Ornato JP, Pearle DL, Sloan MA, Smith SC Jr, Alpert JS, Anderson JL, Faxon DP, Fuster V, Gibbons RJ, Gregoratos G, Halperin JL, Hiratzka LF, Hunt SA, Jacobs AK, Ornato JP. ACC/AHA guidelines for the management of patients with ST-elevation myocardial infarction; A report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines (Committee to Revise the 1999 Guidelines for the Management of patients with acute myocardial infarction). J Am Coll Cardiol. 2004;44:E1-E211.
11. The Thrombolysis in Myocardial Infarction (TIMI) trial. Phase I findings. TIMI Study Group. N Engl J Med. 1985;312:932-936.
12. Early effects of tissue-type plasminogen activator added to conventional therapy on the culprit coronary lesion in patients presenting with ischemic cardiac pain at rest. Results of the Thrombolysis in Myocardial Ischemia (TIMI IIIA) Trial. Circulation. 1993;87:38-52.
13. van 't Hof AW, Liem A, Suryapranata H, Hoorntje JC, de Boer MJ, Zijlstra F. Angiographic assessment of myocardial reperfusion in patients treated with primary angioplasty for acute myocardial infarction: myocardial blush grade. Zwolle Myocardial Infarction Study Group. Circulation. 1998;97:2302-2306. (Pubitemid 28280383)
14. Foltz WD, Al-Kwifi O, Sussman MS, Stainsby JA, Wright GA. Optimized spiral imaging for measurement of myocardial T2 relaxation. Magn Reson Med. 2003;49:1089-1097. (Pubitemid 36627288)
15. Merli E, Sutherland GR, Bijnens B, Fischer A, Chaparro M, Karu T, Sutcliffe S, Marciniak A, Baltabaeva A, Bunce N, Brecker S. Usefulness of changes in left ventricular wall thickness to predict full or partial pressure reperfusion in ST-elevation acute myocardial infarction. Am J Cardiol. 2008;102:249-256.
16. Turschner O, D'hooge J, Dommke C, Claus P, Verbeken E, De Scheerder I, Bijnens B, Sutherland GR. The sequential changes in myocardial thickness and thickening which occur during acute transmural infarction, infarct reperfusion and the resultant expression of reperfusion injury. Eur Heart J. 2004;25:794-803. (Pubitemid 38647940)
17. Schmidt A, Azevedo CF, Cheng A, Gupta SN, Bluemke DA, Foo TK, Gerstenblith G, Weiss RG, Marbán E, Tomaselli GF, Lima JA, Wu KC. Infarct tissue heterogeneity by magnetic resonance imaging identifies enhanced cardiac arrhythmia susceptibility in patients with left ventricular dysfunction. Circulation. 2007;115:2006-2014. (Pubitemid 46625951)
18. Abdel-Aty H, Simonetti O, Friedrich MG. T2-weighted cardiovascular magnetic resonance imaging. J Magn Reson Imaging. 2007;26: 452-459. (Pubitemid 350194566)
19. Karolle BL, Carlson RE, Aisen AM, Buda AJ. Transmural distribution of myocardial edema by NMR relaxometry following myocardial ischemia and reperfusion. Am Heart J. 1991;122(3 Pt 1):655-664.
20. Abdel-Aty H, Cocker M, Meek C, Tyberg JV, Friedrich MG. Edema as a very early marker for acute myocardial ischemia: a cardiovascular magnetic resonance study. J Am Coll Cardiol. 2009;53:1194-1201.
21. Arai AE. Using magnetic resonance imaging to characterize recent myocardial injury: utility in acute coronary syndrome and other clinical scenarios. Circulation. 2008;118:795-796.
22. Verhaert D, Thavendiranathan P, Giri S, Mihai G, Rajagopalan S, Simonetti OP, Raman SV. Direct T2 quantification of myocardial edema in acute ischemic injury. JACC Cardiovasc Imaging. 2011;4:269-278.
23. Friedrich MG. Myocardial edema-a new clinical entity? Nat Rev Cardiol. 2010;7:292-296.
24. Schulz-Menger J. Myocardial edema in acute ischemic injury. JACC Cardiovasc Imaging. 2011;4:279-281.
25. Piper HM, García-Dorado D, Ovize M. A fresh look at reperfusion injury. Cardiovasc Res. 1998;38:291-300. (Pubitemid 28294147)
26. Garcia-Dorado D, Théroux P, Solares J, Alonso J, Fernandez-Avilés F, Elizaga J, Soriano J, Botas J, Munoz R. Determinants of hemorrhagic infarcts. Histologic observations from experiments involving coronary occlusion, coronary reperfusion, and reocclusion. Am J Pathol. 1990;137: 301-311.
27. Mather AN, Fairbairn TA, Ball SG, Greenwood JP, Plein S. Reperfusion haemorrhage as determined by cardiovascular MRI is a predictor of adverse left ventricular remodelling and markers of late arrhythmic risk. Heart. 2011;97:453-459.
28. Beek AM, Nijveldt R, van Rossum AC. Intramyocardial hemorrhage and microvascular obstruction after primary percutaneous coronary intervention. Int J Cardiovasc Imaging. 2010;26:49-55.