Early life stress confers lifelong stress susceptibility in mice via ventral tegmental area OTX2

Science

Volumn 356, Issue 6343, 2017, Pages 1185-1188

  Peña, Catherine J ^a   Kronman, Hope G ^a   Walker, Deena M ^a   Cates, Hannah M ^a   Bagot, Rosemary C ^a,c   Purushothaman, Immanuel ^a   Issler, Orna ^a   Eddie Loh, Yong Hwee ^a   Leong, Tin ^a   Kiraly, Drew D ^a   Goodman, Emma ^a   Neve, Rachael L ^b   Shen, Li ^a   Nestler, Eric J ^a  

^a MOUNT SINAI SCHOOL OF MEDICINE   (United States)

^b MASSACHUSETTS INSTITUTE OF TECHNOLOGY   (United States)

^c MCGILL UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

RNA; TRANSCRIPTION FACTOR OTX2; OTX2 PROTEIN, MOUSE; PROTEIN BINDING; TRANSCRIPTION FACTOR OTX;

ENVIRONMENTAL STRESS; GENE EXPRESSION; NUMERICAL MODEL; RISK ASSESSMENT; RODENT;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DISEASE PREDISPOSITION; EARLY LIFE STRESS; GENE OVEREXPRESSION; JUVENILE; MALE; MOUSE; NONHUMAN; NUCLEAR REPROGRAMMING; PERINATAL PERIOD; PRIORITY JOURNAL; REWARD; RNA SEQUENCE; SOCIAL STRESS; VENTRAL TEGMENTUM; AGE; ANIMAL; C57BL MOUSE; DEPRESSION; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN; GENETICS; PATHOPHYSIOLOGY; PHYSIOLOGICAL STRESS;

MUS;

AGE FACTORS; ANIMALS; DEPRESSION; FEMALE; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; MALE; MICE; MICE, INBRED C57BL; OTX TRANSCRIPTION FACTORS; PROTEIN BINDING; STRESS, PHYSIOLOGICAL; VENTRAL TEGMENTAL AREA;

EID: 85020849330     PISSN: 00368075     EISSN: 10959203     Source Type: Journal    
DOI: 10.1126/science.aan4491     Document Type: Article

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