Young breast cancer patients who develop distant metastasis after surgery have better survival outcomes compared with elderly counterparts

Oncotarget

Volumn 8, Issue 27, 2017, Pages 44851-44859

  Wang, Jingjing ^a   Wang, Jiayu ^a   Li, Qing ^a   Zhang, Pin ^a   Yuan, Peng ^a   Ma, Fei ^a   Luo, Yang ^a   Cai, Ruigang ^a   Fan, Ying ^a   Chen, Shanshan ^a   Li, Qiao ^a   Xu, Binghe ^a  

^a CANCER HOSPITAL   (China)

Author keywords

Breast cancer; Distant metastasis; Locoregional relapse; Prognosis; Young age

Indexed keywords

TRASTUZUMAB;

ADULT; AGED; ARTICLE; BREAST CANCER; CANCER CHEMOTHERAPY; CANCER GRADING; CANCER GROWTH; CANCER PROGNOSIS; CANCER RECURRENCE; CANCER STAGING; CANCER SURVIVAL; CLINICAL FEATURE; DISEASE FREE SURVIVAL; DISTANT METASTASIS; DRUG EFFECT; FEMALE; FOLLOW UP; HUMAN; LYMPH NODE METASTASIS; LYMPH VESSEL; MAJOR CLINICAL STUDY; OUTCOME ASSESSMENT; PARTIAL MASTECTOMY; SURVIVAL TIME; TUMOR INVASION; ADVERSE EVENT; AGE; BREAST TUMOR; KAPLAN MEIER METHOD; MASTECTOMY; METASTASIS; MORTALITY; MULTIMODALITY CANCER THERAPY; PATHOLOGY; PROCEDURES; PROGNOSIS; PROPORTIONAL HAZARDS MODEL; RECURRENT DISEASE; SURVIVAL RATE; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGE FACTORS; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; COMBINED MODALITY THERAPY; FEMALE; HUMANS; KAPLAN-MEIER ESTIMATE; MASTECTOMY; NEOPLASM GRADING; NEOPLASM METASTASIS; NEOPLASM STAGING; PROGNOSIS; PROPORTIONAL HAZARDS MODELS; RECURRENCE; SURVIVAL RATE; TREATMENT OUTCOME; YOUNG ADULT;

EID: 85020697141     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.15268     Document Type: Article

References (29)

1. Ries LAG. SEER Cancer Statistics Review, 1973-1999 Bethesda, MD: National Cancer institute.2002.
2. Siegel R, Ma J, Zou Z, Jemal A. Cancer statistics, 2014. CA Cancer J Clin. 2014; 64: 9-29.
3. Winchester DP. Breast cancer in young women. Surg Clin North Am. 1996; 76: 279-287.
4. Fan L, Strasser-Weippl K, Li JJ, St Louis J, Finkelstein DM, Yu KD, Chen WQ, Shao ZM, Goss PE. Breast cancer in China. Lancet Oncol. 2014; 15: e279-e289.
5. Han W, Kim SW, Park IA, Kang D, Kim SW, Youn YK, Oh SK, Choe KJ, Noh DY. Young age: an independent risk factor for disease-free survival in women with operable breast cancer. BMC Cancer. 2004; 4: 82-89.
6. Ministry of Health and Welfare. Annual Report of Cancer statistics in Korean in 2011. Goyang: Korean Central Cancer Registry. 2012.
7. Dubsky PC, Gnant MF, Taucher S, Roka S, Kandioler D, Pichler-Gebhard B, Agstner I, Seifert M, Sevelda P, Jakesz R. Young age as an independent adverse prognostic factor in premenopausal patients with breast cancer. Clin Breast Cancer. 2002; 3: 65-72.
8. Maggard MA, O'Connell JB, Lane KE, Liu JH, Etzioni DA, Ko CY. Do young breast cancer patients have worse outcomes? J Surg Res. 2003; 113: 109-113.
9. Gajdos C, Tartter PI, Bleiweiss IJ, Bodian C, Brower ST. Stage 0 to stage III breast cancer in young women. J Am Coll Surg. 2000; 190: 523-529.
10. Han W, Kang SY. Relationship between age at diagnosis and outcome of premenopausal breast cancer: age less than 35 years is a reasonable cut-off for defining young age-onset breast cancer. Breast Cancer Res Treat. 2010; 119: 193-200.
11. Anders CK, Hsu DS, Broadwater G, Acharya CR, Foekens JA, Zhang Y, Wang Y, Marcom PK, Marks JR, Febbo PG, Nevins JR, Potti A, Blackwell KL. Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. J Clin Oncol. 2008; 26: 3324-3330.
12. Cancello G, Maisonneuve P, Rotmensz N, Viale G, Mastropasqua MG, Pruneri G, Veronesi P, Torrisi R, Montagna E, Luini A, Intra M, Gentilini O, Ghisini R, et al. Prognostic and adjuvant treatment effects in selected breast cancer subtypes of very young women (< 35 years) with operable breast cancer. Ann Oncol. 2010; 21: 1974-1981.
13. Gnerlich JL, Deshpande AD, Jeffe DB, Sweet A, White N, Margenthaler JA. Elevated breast cancer mortality in women younger than age 40 years compared with older women is attributed to poorer survival in early-stage disease. J Am Coll Surg. 2009; 208: 341-347.
14. Fredholm H, Eaker S, Frisell J, Holmberg L, Fredriksson I, Lindman H. Breast cancer in young women: poor survival despite intensive treatment. Plos One. 2009; 4: e7695.
15. Tang LC, Jin X, Yang HY, He M, Chang H, Shao ZM, Di GH. Luminal B sugtype: a key factor for the worse prognosis of young breast cancer patients in China. BMC Cancer. 2015; 15: 201-207.
16. Tang J, Wu CC, Xie ZM, Luo RZ, Yang MT. Comparison of clinical features and treatment outcome of breast cancers in young and elderly Chinese patients. Breast Care. 2011; 6: 435-440.
17. Kim JK, Kwak BS, Lee JS, Hong SJ, Kim HJ, Son BH, Ahn SH. Do very young Korean breast cancer patients have worse outcomes? Ann Surg Oncol. 2007; 14: 3385-3391.
18. Azim HA Jr, Michiels S, Bedard PL, Singhal SK, Criscitiello C, Ignatiadis M, Haibe-Kains B, Piccart MJ, Sotiriou C, Loi S. Elucidating prognosis and biology of breast cancer arising in young women using gene expression profiling. Clin Cancer Res. 2012, 18: 1341-1351.
19. Sheridan W, Scott T, Caroline S, Yvonne Z, Vanessa B, David V, Karen G, Stephen C. Breast cancer in young women: have the prognostic implications of breast cancer subtypes changed over time? Breast Cancer Res Treat. 2014; 147: 617-629.
20. de la Rochefordiere A, Asselain B, Campana F, Scholl SM, Fenton J, Vilcoq JR, Durand JC, Pouillart P, Magdelenat H, Fourquet A. Age as prognostic factor in premenopausal breast carcinoma. Lancet. 1993; 341: 1039-1043.
21. Early Breast Cancer Trialists' Collaborative Group (EBCTCG), Darby S, McGale P, Correa C, Taylor C, Arriagada R, Clarke M, Cutter D, Davies C, Ewertz M, Godwin J, Gray R, Pierce L, et al. Effect of radiotherapy after breast-conserving surgery on 10-year recurrence and 15-year breast cancer death: meta-analysis of individual patient data for 10,801 women in 17 randomised trials. Lancet. 2011; 378: 1707-1716.
22. Donker M, Litière S, Werutsky G, Julien JP, Fentiman IS, Agresti R, Rouanet P, de Lara CT, Bartelink H, Duez N, Rutgers EJ, Bijker N. Breast-conserving treatment with or without radiotherapy in ductal carcinoma in situ: 15-year recurrence rates and outcome after a recurrence, from the EORTC 10853 randomized phase III trial. J Clin Oncol. 2013; 31: 4054-4059.
23. van Laar C, van der Sangen MJ, Poortmans PM, Nieuwenhuijzen GA, Roukema JA, Roumen RM, Tjan-Heijnen VC, Voogd AC. Local recurrence following breastconserving treatment in women aged 40 years or younger: trends in risk and the impact on prognosis in a populationbased cohort of 1143 patients. Eur J Cancer. 2013; 49: 3093-3101.
24. Moreno-Aspitia A, Perez EA. Anthracycline-and/or taxane-resistant breast cancer: results of a literature review to determine the clinical challenges and current treatment trends. Clin Ther. 2009; 31: 1619-1640.
25. Oostendorp LJ, Stalmeier PF, Donders AR, van der Graaf WT, Ottevanger PB. Efficacy and safety of palliative chemotherapy for patients with advanced breast cancer pretreated with anthracyclines and taxanes: a systematic review. Lancet Oncol. 2011; 12: 1053-1061.
26. Hortobagyi GN, de la Garza Salazar J, Pritchard K, Amadori D, Haidinger R, Hudis CA, Khaled H, Liu MC, Martin M, Namer M, O'Shaughnessy JA, Shen ZZ, Albain KS, ABREAST Investigators. The global breast cancer burden: variations in epidemiology and survival. Clin Breast Cancer. 2005; 6: 391-401.
27. Roche H, Vahdat LT. Treatment of metastatic breast cancer: second line and beyond. Ann Oncol. 2011; 22: 1000-1010.
28. Jassem J, Carroll C, Ward SE, Simpson E, Hind D. The clinical efficacy of cytotoxic agents in locally advanced or metastatic breast cancer patients pretreated with an anthracycline and a taxane: a systematic review. Eur J Cancer. 2009; 45: 2749-2758.
29. Bastiaannet E, Liefers GJ, de Craen AJ, Kuppen PJ, van de Water W, Portielje JE, van der Geest LG, Janssen-Heijnen ML, Dekkers OM, van de Velde CJ, Westendorp RG. Breast cancer in elderly compared to younger patients in the Netherlands: stage at diagnosis, treatment and survival in 127,805 unselected patients. Breast Cancer Res Tr. 2010; 124: 801-807.