Elevated Breast Cancer Mortality in Women Younger than Age 40 Years Compared with Older Women Is Attributed to Poorer Survival in Early-Stage Disease

Journal of the American College of Surgeons

Volumn 208, Issue 3, 2009, Pages 341-347

  Gnerlich, Jennifer L ^a   Deshpande, Anjali D ^a   Jeffe, Donna B ^a   Sweet, Allison ^b   White, Nick ^a   Margenthaler, Julie A ^a  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b American Cancer Society Metro East Region   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ESTROGEN RECEPTOR; PROGESTERONE RECEPTOR;

ADOLESCENT; ADULT; AGED; ARTICLE; BREAST CANCER; CANCER DIAGNOSIS; CANCER MORTALITY; CANCER STAGING; CANCER SURVIVAL; CONTROLLED STUDY; FEMALE; HUMAN; MAJOR CLINICAL STUDY; MASTECTOMY; OUTCOME ASSESSMENT; PRIORITY JOURNAL;

ADULT; AGE DISTRIBUTION; AGE FACTORS; AGED; AGED, 80 AND OVER; BREAST NEOPLASMS; CAUSE OF DEATH; COHORT STUDIES; CONFIDENCE INTERVALS; DISEASE-FREE SURVIVAL; ESTROGEN RECEPTOR ALPHA; FEMALE; HUMANS; LYMPHATIC METASTASIS; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEOPLASM STAGING; PROGNOSIS; RECEPTORS, PROGESTERONE; RETROSPECTIVE STUDIES; SURVIVAL RATE;

EID: 60149090603     PISSN: 10727515     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jamcollsurg.2008.12.001     Document Type: Article

References (20)

1. Bland K.I., Menck H.R., Scott-Conner C.E., et al. The National Cancer Database 10-year survey of breast carcinoma treatment at hospitals in the United States. Cancer 83 (1998) 1262-1273
2. Adami H.O., Malker B., Holmberg L., et al. The relation between survival and age at diagnosis and breast cancer. N Engl J Med 315 (1986) 559-563
3. Chung M., Chang H.R., Bland K.I., et al. Younger women with breast carcinoma have a poorer prognosis than older women. Cancer 77 (1996) 97-103
4. El Saghir N.S., Seoud M., Khalil M.K., et al. Effects of young age at presentation on survival in breast cancer. BMC Cancer 6 (2006) 194
5. Nixon A.J., Neuburg D., Hayes D.F., et al. Relationship of patient age to pathologic features of the tumor and prognosis for patients with stage I and stage II breast cancer. J Clin Oncol 12 (1994) 888-894
6. de la Rochefordiere A., Campana F., Fenton J., et al. Age as a prognostic factor in premenopausal breast cancer. Lancet 341 (1993) 1039-1043
7. Swanson G.M., and Lin C.S. Survival patterns among younger women with breast cancer: the effects of age, race, stage, and treatment. J Natl Cancer Inst Monogr 16 (1994) 69-77
8. Elkhuizen P.H., van de Vijver M.J., Hermans J., et al. Local recurrence after breast-conserving therapy for invasive breast cancer: high incidence in young patients and association with poor survival. Int J Radiat Oncol Biol Phys 40 (1998) 859-867
9. Bollet M.A., Sigal-Zafrani B., Mazeau V., et al. Age remains the first prognostic factor for loco-regional breast cancer recurrence in young (<40 years) women treated with breast conserving surgery first. Radiother Oncol 82 (2007) 272-280
10. Gajdos A., Tartter P.I., Bleiweiss I.J., et al. Stage 0-III breast cancer in young women. J Am Coll Surg 190 (2000) 523-529
11. Albain K.S., Allred D.C., and Clark G.M. Breast cancer outcome and predictor of outcome: are there age differentials?. J Natl Cancer Inst Monogr 16 (1994) 35-42
12. Kollias J., Elston C.W., Ellis I.O., et al. Early-onset breast cancer-histopathological and prognostic considerations. Br J Cancer 75 (1997) 1318-1323
13. Shannon C., and Smith I.E. Breast cancer in adolescents and young women. Eur J Cancer 39 (2003) 2632-2642
14. Anders C.K., Hsu D.S., Broadwater G., et al. Young age at diagnosis correlates with worse prognosis and defines a subset of breast cancers with shared patterns of gene expression. J Clin Oncol 26 (2006) 3324-3330
15. National Cancer Institute. Surveillance, Epidemiology, and End Results. Overview of the SEER Program. http://seer.cancer.gov/about/ Accessed February 1, 2007
16. Winchester D.P., Osteen R.T., and Menk H.R. The National Cancer Data Base report on breast carcinoma characteristics and outcome in relation in age. Cancer 78 (1996) 1838-1843
17. Boyd N.F., Martin L.J., Sun L., et al. Body size, mammographic density, and breast cancer risk. Cancer Epidemiol Biomarkers Prev 15 (2006) 2086-2092
18. Sorlie T., Perou C.M., Tibshirani R., et al. Gene expression patterns of breast carcinomas distinguish tumor subclasses with clinical implications. Proc Natl Acad Sci USA 98 (2001) 10869-10873
19. Sotiriou C., Neo S.Y., McShane L.M., et al. Breast cancer classification and prognosis based on gene expression profiles from a population based study. Proc Natl Acad Sci U S A 100 (2003) 10393-10398
20. Merrill R.M., and Dearden K.A. How representative are the surveillance, epidemiology, and end results (SEER) program cancer data of the United States. Cancer Cause Control 15 (2004) 1027-1034