Killing kinetics of minocycline, doxycycline and tosufloxacin against macrolide-resistant Mycoplasma pneumoniae

International Journal of Antimicrobial Agents

Volumn 50, Issue 2, 2017, Pages 255-257

  Morozumi, Miyuki ^a   Okada, Takafumi ^b   Tajima, Takeshi ^c   Ubukata, Kimiko ^a   Iwata, Satoshi ^a  

^a KEIO UNIVERSITY SCHOOL OF MEDICINE   (Japan)

^b SHIKOKU MEDICAL CENTER FOR CHILDREN AND ADULTS   (Japan)

^c Hakujikai Memorial Hospital   (Japan)

Author keywords

Doxycycline; Macrolide resistant Mycoplasma pneumoniae; Minocycline; Paediatrics; Time kill assay; Tosufloxacin

Indexed keywords

ANTIBIOTIC AGENT; AZITHROMYCIN; CLARITHROMYCIN; DOXYCYCLINE; MACROLIDE; MINOCYCLINE; TOSUFLOXACIN; ANTIINFECTIVE AGENT; NAPHTHYRIDINE DERIVATIVE; QUINOLONE DERIVATIVE;

ANTIBIOTIC RESISTANCE; ANTIBIOTIC SENSITIVITY; ARTICLE; BACTERIAL CELL; BACTERICIDAL ACTIVITY; BACTERIUM CULTURE; CELL VIABILITY; CHILD; COLONY FORMING UNIT; DRUG BLOOD LEVEL; DRUG DETERMINATION; DRUG EXPOSURE; DRUG HALF LIFE; DRUG TISSUE LEVEL; HUMAN; MAXIMUM PLASMA CONCENTRATION; MINIMUM INHIBITORY CONCENTRATION; MYCOPLASMA PNEUMONIAE; NONHUMAN; PHARMACOKINETIC PARAMETERS; PRIORITY JOURNAL; BACTERIAL COUNT; DRUG EFFECTS; EPIDEMIC; FEMALE; INFANT; ISOLATION AND PURIFICATION; JAPAN; MALE; MICROBIAL SENSITIVITY TEST; MICROBIAL VIABILITY; MICROBIOLOGY; MYCOPLASMA PNEUMONIA; NEWBORN; PRESCHOOL CHILD; TIME FACTOR;

ANTI-BACTERIAL AGENTS; CHILD; CHILD, PRESCHOOL; COLONY COUNT, MICROBIAL; DISEASE OUTBREAKS; DOXYCYCLINE; DRUG RESISTANCE, BACTERIAL; FEMALE; FLUOROQUINOLONES; HUMANS; INFANT; INFANT, NEWBORN; JAPAN; MACROLIDES; MALE; MICROBIAL SENSITIVITY TESTS; MICROBIAL VIABILITY; MINOCYCLINE; MYCOPLASMA PNEUMONIAE; NAPHTHYRIDINES; PNEUMONIA, MYCOPLASMA; TIME FACTORS;

EID: 85020657107     PISSN: 09248579     EISSN: 18727913     Source Type: Journal    
DOI: 10.1016/j.ijantimicag.2017.02.027     Document Type: Article

References (16)

1. Okada, T., Morozumi, M., Tajima, T., Hasegawa, M., Sakata, H., Ohnari, S., et al. Rapid effectiveness of minocycline or doxycycline against macrolide-resistant Mycoplasma pneumoniae infection in a 2011 outbreak among Japanese children. Clin Infect Dis 55 (2012), 1642–1649.
2. Kawai, Y., Miyashita, N., Kubo, M., Akaike, H., Kato, A., Nishizawa, Y., et al. Nationwide surveillance of macrolide-resistant Mycoplasma pneumoniae infection in pediatric patients. Antimicrob Agents Chemother 57 (2013), 4046–4049.
3. Hong, K.B., Choi, E.H., Lee, H.J., Lee, S.Y., Cho, E.Y., Choi, J.H., et al. Macrolide resistance of Mycoplasma pneumoniae, South Korea, 2000–2011. Emerg Infect Dis 19 (2013), 1281–1284.
4. Zhao, F., Liu, G., Wu, J., Cao, B., Tao, X., He, L., et al. Surveillance of macrolide-resistant Mycoplasma pneumoniae in Beijing, China, from 2008 to 2013. Antimicrob Agents Chemother 57 (2012), 1521–1523.
5. Chironna, M., Sallustio, A., Esposito, S., Perulli, M., Chinellato, I., Di Bari, C., et al. Emergence of macrolide-resistant strains during an outbreak of Mycoplasma pneumoniae infections in children. J Antimicrob Chemother 66 (2011), 734–737.
6. Dumke, R., von Baum, H., Lück, P.C., Jacobs, E., Occurrence of macrolide-resistant Mycoplasma pneumoniae strains in Germany. Clin Microbiol Infect 16 (2010), 613–616.
7. Peuchant, O., Ménard, A., Renaudin, H., Morozumi, M., Ubukata, K., Bébéar, C.M., et al. Increased macrolide resistance of Mycoplasma pneumoniae in France directly detected in clinical specimens by real-time PCR and melting curve analysis. J Antimicrob Chemother 64 (2009), 52–58.
8. Zheng, X., Lee, S., Selvarangan, R., Qin, X., Tang, Y.W., Stiles, J., et al. Macrolide-resistant Mycoplasma pneumoniae, United States. Emerg Infect Dis 21 (2015), 1470–1472.
9. Eshaghi, A., Memari, N., Tang, P., Olsha, R., Farrell, D.J., Low, D.E., et al. Macrolide-resistant Mycoplasma pneumoniae in humans, Ontario, Canada. Emerg Infect Dis, 2013, 2010–2011, 19, 10.3201/eid1909.121466.
10. Guidelines for the management of respiratory infectious diseases in children in Japan, 2011, Japanese Society of Pediatric Pulmonology; Japanese Society for Pediatric Infectious Diseases.
11. Brown, R.J., Holden, M.T., Spiller, O.B., Chalker, V.J., Development of a multilocus sequence typing scheme for molecular typing of Mycoplasma pneumoniae. J Clin Microbiol 53 (2015), 3195–3203.
12. Morozumi, M., Hasegawa, K., Kobayashi, R., Inoue, N., Iwata, S., Kuroki, H., et al. Emergence of macrolide-resistant Mycoplasma pneumoniae with a 23S rRNA gene mutation. Antimicrob Agents Chemother 49 (2005), 2302–2306.
13. Foulds, G., Shepard, R.M., Johnson, R.B., The pharmacokinetics of azithromycin in human serum and tissues. J Antimicrob Chemother 25 (1990), 73–82.
14. Nakazawa, S., Oka, S., Sato, H., Watanabe, O., Niino, K., Effects of dry syrup minocycline (Minomycin ‘Lederle’) in the pediatric field. Jpn J Antibiot 25 (1972), 288–294 in Japanese.
15. Sunakawa, K., Iwai, N., Iwata, S., Ouchi, K., Sakata, H., Suzuki, K., et al. Population pharmacokinetics and pharmacodynamics of tosufloxacin granules in pediatric infectious diseases. Jpn J Chemother 58 (2010), 69–77 in Japanese.
16. Waites, K.B., Taylor-Robinson, D., Mycoplasma and ureaplasma. Versalovic, J., Carroll, K.C., Funke, G., Jorgense, J.H., Landry, M.L., Warnock, D.W., (eds.) Manual of clinical microbiology, 10th ed, 2011, American Society for Microbiology, Washington, DC, 970–985.