Association of increasing GFR with change in albuminuria in the general population

Clinical Journal of the American Society of Nephrology

Volumn 11, Issue 12, 2016, Pages 2186-2194

  Melsom, Toralf ^a   Stefansson, Vidar ^a   Schei, Jørgen ^a   Solbu, Marit ^a   Jenssen, Trond ^a,b   Wilsgaard, Tom ^c   Eriksen, Bjørn O ^a  

^a UNIVERSITY OF TROMSØ   (Norway)

^b UNIVERSITY HOSPITAL OF NORTH NORWAY   (Norway)

^c OSLO UNIVERSITY HOSPITAL   (Norway)

Author keywords

Comparative effectiveness; Confidence Intervals; Creatinine; Diabetes management; Diabetes mellitus; Diabetes Mellitus, Type 2; Diabetic nephropathy; Glucose; Humans; Insulin; Kidney; Kidney Failure, Chronic; Metformin; Propensity Score; Retrospective Studies; Sulfonylurea Compounds; Treatment intensification; Veterans

Indexed keywords

ALBUMIN; ANGIOTENSIN RECEPTOR ANTAGONIST; ANTIHYPERTENSIVE AGENT; C REACTIVE PROTEIN; CREATININE; DIPEPTIDYL CARBOXYPEPTIDASE INHIBITOR; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; IOHEXOL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; TRIACYLGLYCEROL;

ADULT; ALBUMINURIA; ALCOHOL CONSUMPTION; ARTICLE; BODY MASS; CREATININE CLEARANCE; DISEASE ASSOCIATION; DRUG CLEARANCE; EXERCISE; FEMALE; GLOMERULUS FILTRATION RATE; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; SENSITIVITY ANALYSIS; SMOKING; FOLLOW UP; NEPHRON; PATHOPHYSIOLOGY; RISK FACTOR; URINE;

ALBUMINURIA; CREATININE; FEMALE; FOLLOW-UP STUDIES; GLOMERULAR FILTRATION RATE; HUMANS; MALE; MIDDLE AGED; NEPHRONS; RISK FACTORS;

EID: 85020551606     PISSN: 15559041     EISSN: 1555905X     Source Type: Journal    
DOI: 10.2215/CJN.04940516     Document Type: Article

References (51)

1. Naghavi M, Wang H; GBD 2013 Mortality and Causes of Death Collaborators: Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: A systematic analysis for the Global Burden of Disease Study 2013. Lancet 385: 117-171, 2015
2. Matsushita K, van der Velde M, Astor BC, Woodward M, Levey AS, de Jong PE, Coresh J, Gansevoort RT; Chronic Kidney Disease Prognosis Consortium: Association of estimated glomerular filtration rate and albuminuria with all-cause and cardiovascular mortality in general population cohorts: A collaborative metaanalysis. Lancet 375: 2073-2081, 2010
3. Turin TC, Coresh J, Tonelli M, Stevens PE, de Jong PE, Farmer CK, Matsushita K, Hemmelgarn BR: Change in the estimated glomerular filtration rate over time and risk of all-cause mortality. Kidney Int 83: 684-691, 2013
4. Coresh J, Turin TC, Matsushita K, Sang Y, Ballew SH, Appel LJ, Arima H, Chadban SJ, Cirillo M, Djurdjev O, Green JA, Heine GH, Inker LA, Irie F, Ishani A, Ix JH, Kovesdy CP, Marks A, Ohkubo T, Shalev V, Shankar A, Wen CP, de Jong PE, Iseki K, Stengel B, Gansevoort RT, Levey AS; CKD Prognosis Consortium: Decline in estimated glomerular filtration rate and subsequent risk of end-stage renal disease and mortality. JAMA 311: 2518-2531, 2014
5. Brenner BM, Lawler EV, Mackenzie HS: The hyperfiltration theory: A paradigm shift in nephrology. Kidney Int 49: 1774-1777, 1996
6. Ruggenenti P, Remuzzi G: Time to abandon microalbuminuria? Kidney Int 70: 1214-1222, 2006
7. Nelson RG, Bennett PH, Beck GJ, Tan M, Knowler WC, Mitch WE, Hirschman GH, Myers BD; Diabetic Renal Disease Study Group: Development and progression of renal disease in Pima Indians with non-insulin-dependent diabetes mellitus. N Engl J Med 335: 1636-1642, 1996
8. Jerums G, Premaratne E, Panagiotopoulos S, MacIsaac RJ: The clinical significance of hyperfiltration in diabetes. Diabetologia 53: 2093-2104, 2010
9. Melsom T, Schei J, Stefansson VT, Solbu MD, Jenssen TG, Mathisen UD, Wilsgaard T, Eriksen BO: Prediabetes and risk of glomerular hyperfiltration and albuminuria in the general nondiabetic population: A prospective cohort study. Am J Kidney Dis 67: 841-850, 2016
10. Melsom T, Mathisen UD, Ingebretsen OC, Jenssen TG, Njølstad I, Solbu MD, Toft I, Eriksen BO: Impaired fasting glucose is associated with renal hyperfiltration in the general population. Diabetes Care 34: 1546-1551, 2011
11. Okada R, Yasuda Y, Tsushita K, Wakai K, Hamajima N, Matsuo S: Glomerular hyperfiltration in prediabetes and prehypertension. Nephrol Dial Transplant 27: 1821-1825, 2012
12. Mathisen UD, Melsom T, Ingebretsen OC, Jenssen TG, Njølstad I, Solbu MD, Toft I, Eriksen BO: Ambulatory blood pressure is associated withmeasured glomerular filtration rate in the general middle-aged population. J Hypertens 30: 497-504, 2012
13. Wuerzner G, Pruijm M, Maillard M, Bovet P, Renaud C, Burnier M, Bochud M: Marked association between obesity and glomerular hyperfiltration: A cross-sectional study in an African population. Am J Kidney Dis 56: 303-312, 2010
14. Pinto-Sietsma SJ, Mulder J, Janssen WM, Hillege HL, de Zeeuw D, de Jong PE: Smoking is related to albuminuria and abnormal renal function in nondiabetic persons. Ann InternMed 133: 585-591, 2000
15. Mathisen UD, Melsom T, Ingebretsen OC, Jenssen T, Njølstad I, Solbu MD, Toft I, Eriksen BO: Estimated GFR associates with cardiovascular risk factors independently ofmeasuredGFR. J Am Soc Nephrol 22: 927-937, 2011
16. Hoy WE, Douglas-Denton RN, Hughson MD, Cass A, Johnson K, Bertram JF: A stereological study of glomerular number and volume: Preliminary findings in a multiracial study of kidneys at autopsy. Kidney Int Suppl 83: S31-S37, 2003
17. Inker LA, Schmid CH, Tighiouart H, Eckfeldt JH, Feldman HI, Greene T, Kusek JW, Manzi J, Van Lente F, Zhang YL, Coresh J, Levey AS; CKD-EPI Investigators: Estimating glomerular filtration rate fromserum creatinine and cystatin C. N Engl J Med 367: 20-29, 2012
18. Rule AD, Bailey KR, Lieske JC, Peyser PA, Turner ST: Estimating the glomerular filtration rate from serum creatinine is better than from cystatin C for evaluating risk factors associatedwith chronic kidney disease. Kidney Int 83: 1169-1176, 2013
19. Melsom T, Fuskevåg OM, Mathisen UD, Strand H, Schei J, Jenssen T, Solbu M, Eriksen BO: Estimated GFR is biased by nontraditional cardiovascular risk factors. Am J Nephrol 41: 7-15, 2015
20. Eriksen BO, Mathisen UD, Melsom T, Ingebretsen OC, Jenssen TG, Njølstad I, Solbu MD, Toft I: Cystatin C is not a better estimator of GFR than plasma creatinine in the general population. Kidney Int 78: 1305-1311, 2010
21. Nilsson-Ehle P: Iohexol clearance for the determination of glomerular filtration rate: 15 years’ experience in clinical practice. EJIFCC 13: 1-5, 2002
22. Jacobsson L: A method for the calculation of renal clearance based on a single plasma sample. Clin Physiol 3: 297-305, 1983
23. Eriksen BO, Stefansson VT, Jenssen TG, Mathisen UD, Schei J, Solbu MD, Wilsgaard T, Melsom T: Elevated blood pressure is not associated with accelerated glomerular filtration rate decline in the general non-diabetic middle-aged population. Kidney Int 90: 404-410, 2016
24. Solbu MD, Kronborg J, Eriksen BO, Jenssen TG, Toft I: Cardiovascular risk-factors predict progression of urinary albuminexcretion in a general, non-diabetic population: A gender-specific follow-up study. Atherosclerosis 201: 398-406, 2008
25. Levey AS, de Jong PE, Coresh J, El Nahas M, Astor BC, Matsushita K, Gansevoort RT, Kasiske BL, Eckardt KU: The definition, classification, and prognosis of chronic kidney disease: A KDIGO Controversies Conference report. Kidney Int 80: 17-28, 2011
26. Melsom T, Mathisen UD, Eilertsen BAW, Ingebretsen OC, Jenssen T, Njølstad I, Solbu MD, Toft I, Eriksen BO: Physical exercise, fasting glucose, and renal hyperfiltration in the general population: The Renal IohexolClearance Survey in Tromsø 6 (RENIS-T6). Clin J Am Soc Nephrol 7: 1801-1810, 2012
27. Hirji KF, Mehta CR, Patel NR: Computing distributions for exact logistic regression. J Am Stat Assoc 82: 1110-1117, 1987
28. Royston P, Ambler G, Sauerbrei W: The use of fractional polynomials to model continuous risk variables in epidemiology. Int J Epidemiol 28: 964-974, 1999
29. Cachat F, Combescure C, Cauderay M, Girardin E, Chehade H: A systematic review of glomerular hyperfiltration assessment and definition in the medical literature. Clin J Am Soc Nephrol 10: 382-389, 2015
30. Kremers WK, Denic A, Lieske JC, Alexander MP, Kaushik V, Elsherbiny HE, Chakkera HA, Poggio ED, Rule AD: Distinguishing age-related from disease-related glomerulosclerosis on kidney biopsy: The Aging Kidney Anatomy study. Nephrol Dial Transplant 30: 2034-2039, 2015
31. Kasiske BL: Relationship between vascular disease and ageassociated changes in the human kidney. Kidney Int 31: 1153-1159, 1987
32. Pinto-Sietsma SJ, Janssen WM, Hillege HL, Navis G, De Zeeuw D, De Jong PE:Urinary albumin excretion is associated with renal functional abnormalities in a nondiabetic population. J Am Soc Nephrol 11: 1882-1888, 2000
33. Palatini P, Mos L, Ballerini P, Mazzer A, Saladini F, Bortolazzi A, Cozzio S, Casiglia E; HARVEST Investigators: Relationship between GFR and albuminuria in stage 1 hypertension. Clin J Am Soc Nephrol 8: 59-66, 2013
34. Thomas MC, Moran JL, Harjutsalo V, Thorn L, Wadén J, Saraheimo M, Tolonen N, Leiviskä J, Jula A, Forsblom C, Groop PH; FinnDiane Study Group: Hyperfiltration in type 1 diabetes: Does it exist and does it matter for nephropathy? Diabetologia 55: 1505-1513, 2012
35. Ruggenenti P, Porrini EL, Gaspari F, Motterlini N, Cannata A, Carrara F, Cella C, Ferrari S, Stucchi N, Parvanova A, Iliev I, Dodesini AR, Trevisan R, Bossi A, Zaletel J, Remuzzi G; GFR Study Investigators: Glomerular hyperfiltration and renal disease progression in type 2 diabetes. Diabetes Care 35: 2061-2068, 2012
36. Ribstein J, du Cailar G, Mimran A: Combined renal effects of overweight and hypertension. Hypertension 26: 610-615, 1995
37. Tomaszewski M, Charchar FJ, Maric C, McClure J, Crawford L, Grzeszczak W, Sattar N, Zukowska-Szczechowska E, Dominiczak AF: Glomerular hyperfiltration: A new marker of metabolic risk. Kidney Int 71: 816-821, 2007
38. Palatini P, Dorigatti F, Saladini F, Benetti E, Mos L, Mazzer A, Zanata G, Garavelli G, Casiglia E: Factors associated with glomerular hyperfiltration in the early stage of hypertension. Am J Hypertens 25: 1011-1016, 2012
39. Srivastava T, Celsi GE, Sharma M, Dai H, McCarthy ET, Ruiz M, Cudmore PA, Alon US, Sharma R, Savin VA: Fluid flow shear stress over podocytes is increased in the solitary kidney. Nephrol Dial Transplant 29: 65-72, 2014
40. Kriz W, Lemley KV: A potential role for mechanical forces in the detachment of podocytes and the progression of CKD. J Am Soc Nephrol 26: 258-269, 2015
41. Glassock RJ, Rule AD: The implications of anatomical and functional changes of the aging kidney: With an emphasis on the glomeruli. Kidney Int 82: 270-277, 2012
42. Elsherbiny HE, Alexander MP, Kremers WK, Park WD, Poggio ED, Prieto M, Lieske JC, Rule AD: Nephron hypertrophy and glomerulosclerosis and their association with kidney function and risk factors among living kidney donors. Clin J Am Soc Nephrol 9: 1892-1902, 2014
43. Hodgin JB, Bitzer M, Wickman L, Afshinnia F, Wang SQ, O’Connor C, Yang Y, Meadowbrooke C, Chowdhury M, Kikuchi M, Wiggins JE, Wiggins RC: Glomerular aging and focal global glomerulosclerosis: A podometric perspective. J AmSoc Nephrol 26: 3162-3178, 2015
44. Luyckx VA, Bertram JF, Brenner BM, Fall C, Hoy WE, Ozanne SE, Vikse BE: Effect of fetal and child health on kidney development and long-term risk of hypertension and kidney disease. Lancet 382: 273-283, 2013
45. Chagnac A, Weinstein T, Herman M, Hirsh J, Gafter U, Ori Y: The effects of weight loss on renal function in patients with severe obesity. J Am Soc Nephrol 14: 1480-1486, 2003
46. Cherney DZ, Perkins BA, Soleymanlou N, Maione M, Lai V, Lee A, Fagan NM, Woerle HJ, Johansen OE, Broedl UC, von Eynatten M: Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 129: 587-597, 2014
47. Holtkamp FA, de Zeeuw D, Thomas MC, Cooper ME, de Graeff PA, Hillege HJ, Parving HH, Brenner BM, Shahinfar S, Lambers Heerspink HJ: An acute fall in estimated glomerular filtration rate during treatmentwith losartan predicts a slower decrease in longterm renal function. Kidney Int 80: 282-287, 2011
48. Górriz JL, Nieto J, Navarro-González JF, Molina P, Martínez-Castelao A, Pallardó LM: Nephroprotection by hypoglycemic agents: Do we have supporting data? J Clin Med 4: 1866-1889, 2015
49. Bolignano D, Zoccali C: Effects of weight loss on renal function in obese CKD patients: A systematic review. Nephrol Dial Transplant 28[Suppl 4]: iv82-iv98, 2013
50. Eriksen BO, Løchen ML, Arntzen KA, Bertelsen G, Eilertsen BA, von Hanno T, Herder M, Jenssen TG, Mathisen UD, Melsom T, Njølstad I, Solbu MD, Toft I, Mathiesen EB: Subclinical cardiovascular disease is associated with a high glomerular filtration rate in the nondiabetic general population. Kidney Int 86: 146-153, 2014
51. Stevens LA, Levey AS: Measured GFR as a confirmatory test for estimated GFR. J Am Soc Nephrol 20: 2305-2313, 2009