Astroglial versus Neuronal D-Serine: Fact Checking

Trends in Neurosciences

Volumn 40, Issue 9, 2017, Pages 517-520

  Papouin, Thomas ^a   Henneberger, Christian ^b,c,d   Rusakov, Dmitri A ^c   Oliet, Stéphane H R ^e  

^a TUFTS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF BONN   (Germany)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d GERMAN CENTER FOR NEURODEGENERATIVE DISEASES DZNE   (Germany)

^e UNIVERSITÉ DE BORDEAUX   (France)

Author keywords

[No Author keywords available]

Indexed keywords

DEXTRO SERINE; ISOMERASE; SERINE ARGININE RICH PROTEIN; SERINE RACEMASE; UNCLASSIFIED DRUG; SERINE;

AMINO ACID SYNTHESIS; GENE SILENCING; LETTER; MACROGLIA; NERVE CELL; NEUROTRANSMISSION; PRIORITY JOURNAL; ASTROCYTE;

ASTROCYTES; NEURONS; SERINE;

EID: 85020408265     PISSN: 01662236     EISSN: 1878108X     Source Type: Journal    
DOI: 10.1016/j.tins.2017.05.007     Document Type: Letter

References (15)

1. Wolosker, H., et al. The rise and fall of the D-serine-mediated gliotransmission hypothesis. Trends Neurosci. 39 (2016), 712–721.
2. 2+ signaling. Science 327 (2010), 1250–1254.
3. −/− mice in brain slices and during startle responses in vivo. Nat. Neurosci. 18 (2015), 708–717.
4. Bergersen, L.H., et al. Immunogold detection of L-glutamate and D-serine in small synaptic-like microvesicles in adult hippocampal astrocytes. Cereb. Cortex 22 (2012), 1690–1697.
5. Takata, N., et al. Astrocyte calcium signaling transforms cholinergic modulation to cortical plasticity in vivo. J. Neurosci. 31 (2011), 18155–18165.
6. Sultan, S., et al. Synaptic integration of adult-born hippocampal neurons is locally controlled by astrocytes. Neuron 88 (2015), 957–972.
7. Henneberger, C., et al. Long-term potentiation depends on release of D-serine from astrocytes. Nature 463 (2010), 232–236.
8. Martineau, M., et al. Storage and uptake of D-serine into astrocytic synaptic-like vesicles specify gliotransmission. J. Neurosci. 33 (2013), 3413–3423.
9. Ehmsen, J.T., et al. D-serine in glia and neurons derives from 3-phosphoglycerate dehydrogenase. J. Neurosci. 33 (2013), 12464–12469.
10. Foltyn, V.N., et al. Serine racemase modulates intracellular D-serine levels through an α,β-elimination activity. J. Biol. Chem. 280 (2005), 1754–1763.
11. Medvedev, N., et al. Glia selectively approach synapses on thin dendritic spines. Philos. Trans. R. Soc. Lond. B Biol. Sci., 369, 2014, 20140047.
12. Rosenberg, D., et al. Neuronal release of D-serine: a physiological pathway controlling extracellular D-serine concentration. FASEB J. 24 (2010), 2951–2961.
13. Safory, H., et al. The alanine–serine–cysteine-1 (Asc-1) transporter controls glycine levels in the brain and is required for glycinergic inhibitory transmission. EMBO Rep. 16 (2015), 590–598.
14. Benneyworth, M.A., et al. Cell selective conditional null mutations of serine racemase demonstrate a predominate localization in cortical glutamatergic neurons. Cell. Mol. Neurobiol. 32 (2012), 613–624.
15. Martineau, M., et al. Confocal imaging and tracking of the exocytotic routes for D-serine-mediated gliotransmission. Glia 56 (2008), 1271–1284.