-
1
-
-
77956648156
-
N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: The final common pathway on the road to schizophrenia?
-
Kantrowitz JT, Javitt DC. N-methyl-d-aspartate (NMDA) receptor dysfunction or dysregulation: the final common pathway on the road to schizophrenia? Brain Res Bull. 2010;83:108-121.
-
(2010)
Brain Res Bull.
, vol.83
, pp. 108-121
-
-
Kantrowitz, J.T.1
Javitt, D.C.2
-
2
-
-
0025952455
-
Recent advances in the phencyclidine model of schizophrenia
-
Javitt DC, Zukin SR. Recent advances in the phencyclidine model of schizophrenia. Am J Psychiatry. 1991;148:1301-1308.
-
(1991)
Am J Psychiatry.
, vol.148
, pp. 1301-1308
-
-
Javitt, D.C.1
Zukin, S.R.2
-
3
-
-
0028323167
-
Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses
-
Krystal JH, Karper LP, Seibyl JP, et al. Subanesthetic effects of the noncompetitive NMDA antagonist, ketamine, in humans. Psychotomimetic, perceptual, cognitive, and neuroendocrine responses. Arch Gen Psychiatry. 1994;51:199-214.
-
(1994)
Arch Gen Psychiatry.
, vol.51
, pp. 199-214
-
-
Krystal, J.H.1
Karper, L.P.2
Seibyl, J.P.3
-
4
-
-
84866652398
-
Capturing the angel in "angel dust": Twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans
-
Moghaddam B, Krystal JH. Capturing the angel in "angel dust": twenty years of translational neuroscience studies of NMDA receptor antagonists in animals and humans. Schizophr Bull. 2012;38:942-949.
-
(2012)
Schizophr Bull.
, vol.38
, pp. 942-949
-
-
Moghaddam, B.1
Krystal, J.H.2
-
5
-
-
20444501679
-
Mismatch negativity in schizophrenia: A meta-analysis
-
Umbricht D, Krljes S. Mismatch negativity in schizophrenia: a meta-analysis. Schizophr Res. 2005;76:1-23.
-
(2005)
Schizophr Res.
, vol.76
, pp. 1-23
-
-
Umbricht, D.1
Krljes, S.2
-
6
-
-
84863624924
-
Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia
-
Light GA, Swerdlow NR, Rissling AJ, et al. Characterization of neurophysiologic and neurocognitive biomarkers for use in genomic and clinical outcome studies of schizophrenia. PLoS One. 2012;7:e39434.
-
(2012)
PLoS One.
, vol.7
, pp. e39434
-
-
Light, G.A.1
Swerdlow, N.R.2
Rissling, A.J.3
-
7
-
-
84946212713
-
A meta-analysis of mismatch negativity in schizophrenia: From clinical risk to disease specificity and progression
-
Erickson MA, Ruffle A, Gold JM. A meta-analysis of mismatch negativity in schizophrenia: from clinical risk to disease specificity and progression. Biol Psychiatry. 2016;79:980-987.
-
(2016)
Biol Psychiatry.
, vol.79
, pp. 980-987
-
-
Erickson, M.A.1
Ruffle, A.2
Gold, J.M.3
-
8
-
-
84925879509
-
Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: Characterization of demographic, clinical, cognitive, and functional correlates in COGS-2
-
Light GA, Swerdlow NR, Thomas ML, et al. Validation of mismatch negativity and P3a for use in multi-site studies of schizophrenia: characterization of demographic, clinical, cognitive, and functional correlates in COGS-2. Schizophr Res. 2015;163:63-72.
-
(2015)
Schizophr Res.
, vol.163
, pp. 63-72
-
-
Light, G.A.1
Swerdlow, N.R.2
Thomas, M.L.3
-
9
-
-
84857625731
-
Differential relationships of mismatch negativity and visual p1 deficits to premorbid characteristics and functional outcome in schizophrenia
-
Friedman T, Sehatpour P, Dias E, et al. Differential relationships of mismatch negativity and visual p1 deficits to premorbid characteristics and functional outcome in schizophrenia. Biol Psychiatry. 2012;71: 521-529.
-
(2012)
Biol Psychiatry.
, vol.71
, pp. 521-529
-
-
Friedman, T.1
Sehatpour, P.2
Dias, E.3
-
10
-
-
0029859204
-
Role of cortical N-methyl-daspartate receptors in auditory sensory memory and mismatch negativity generation: Implications for schizophrenia
-
Javitt DC, Steinschneider M, Schroeder CE, et al. Role of cortical N-methyl-daspartate receptors in auditory sensory memory and mismatch negativity generation: implications for schizophrenia. Proc Natl Acad Sci U S A. 1996;93:11962-11967.
-
(1996)
Proc Natl Acad Sci U S A.
, vol.93
, pp. 11962-11967
-
-
Javitt, D.C.1
Steinschneider, M.2
Schroeder, C.E.3
-
11
-
-
0033663587
-
Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: Implications for models of cognitive deficits in schizophrenia
-
Umbricht D, Schmid L, Koller R, et al. Ketamine-induced deficits in auditory and visual context-dependent processing in healthy volunteers: implications for models of cognitive deficits in schizophrenia. Arch Gen Psychiatry. 2000;57:1139-1147.
-
(2000)
Arch Gen Psychiatry.
, vol.57
, pp. 1139-1147
-
-
Umbricht, D.1
Schmid, L.2
Koller, R.3
-
12
-
-
84861050979
-
Glutamatergic modulation of auditory information processing in the human brain
-
Gunduz-Bruce H, Reinhart RM, Roach BJ, et al. Glutamatergic modulation of auditory information processing in the human brain. Biol Psychiatry. 2012;71:969-977.
-
(2012)
Biol Psychiatry.
, vol.71
, pp. 969-977
-
-
Gunduz-Bruce, H.1
Reinhart, R.M.2
Roach, B.J.3
-
13
-
-
0001325240
-
Effects of risperidone on auditory event-related potentials in schizophrenia
-
Umbricht D, Javitt D, Novak G, et al. Effects of risperidone on auditory event-related potentials in schizophrenia. Int J Neuropsychopharmacol. 1999;2:299-304.
-
(1999)
Int J Neuropsychopharmacol.
, vol.2
, pp. 299-304
-
-
Umbricht, D.1
Javitt, D.2
Novak, G.3
-
14
-
-
84946433578
-
Neural substrates of auditory emotion recognition deficits in schizophrenia
-
Kantrowitz JT, Hoptman MJ, Leitman DI, et al. Neural substrates of auditory emotion recognition deficits in schizophrenia. J Neurosci. 2015; 35:14909-14921.
-
(2015)
J Neurosci.
, vol.35
, pp. 14909-14921
-
-
Kantrowitz, J.T.1
Hoptman, M.J.2
Leitman, D.I.3
-
15
-
-
84900411478
-
Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: A randomized, double-blind, proof-of-concept study
-
Umbricht D, Alberati D, Martin-Facklam M, et al. Effect of bitopertin, a glycine reuptake inhibitor, on negative symptoms of schizophrenia: a randomized, double-blind, proof-of-concept study. JAMA Psychiatry. 2014; 71:637-646.
-
(2014)
JAMA Psychiatry.
, vol.71
, pp. 637-646
-
-
Umbricht, D.1
Alberati, D.2
Martin-Facklam, M.3
-
16
-
-
84997523832
-
Bitopertin in schizophrenia: Glass half full?
-
Javitt DC. Bitopertin in schizophrenia: glass half full? Lancet Psychiatry. 2016;3:1092-1093.
-
(2016)
Lancet Psychiatry.
, vol.3
, pp. 1092-1093
-
-
Javitt, D.C.1
-
17
-
-
84906815790
-
Efficacy and safety of adjunctive bitopertin (10 and 20 mg) versus placebo in subjects with persistent predominant negative symptoms of schizophrenia treated with antipsychotics-results from the Phase III FlashLyte Study
-
Blaettler T, Bugarski-Kirola D, Fleischhacker WW, et al. Efficacy and safety of adjunctive bitopertin (10 and 20 mg) versus placebo in subjects with persistent predominant negative symptoms of schizophrenia treated with antipsychotics-results from the Phase III FlashLyte Study. Schizophr Res. 2014;158:e2-e3.
-
(2014)
Schizophr Res.
, vol.158
, pp. e2-e3
-
-
Blaettler, T.1
Bugarski-Kirola, D.2
Fleischhacker, W.W.3
-
18
-
-
84997109194
-
Efficacy and safety of adjunctive bitopertin versus placebo in patients with suboptimally controlled symptoms of schizophrenia treated with antipsychotics: Results from three phase 3, randomised, double-blind, parallel-group, placebo-controlled, multicentre studies in the SearchLyte clinical trial programme
-
Bugarski-Kirola D, Iwata N, Sameljak S, et al. Efficacy and safety of adjunctive bitopertin versus placebo in patients with suboptimally controlled symptoms of schizophrenia treated with antipsychotics: results from three phase 3, randomised, double-blind, parallel-group, placebo-controlled, multicentre studies in the SearchLyte clinical trial programme. Lancet Psychiatry. 2016;3:1115-1128.
-
(2016)
Lancet Psychiatry.
, vol.3
, pp. 1115-1128
-
-
Bugarski-Kirola, D.1
Iwata, N.2
Sameljak, S.3
-
19
-
-
84919608198
-
The NMDA receptor 'glycine modulatory site' in schizophrenia: D-serine, glycine, and beyond
-
Balu DT, Coyle JT. The NMDA receptor 'glycine modulatory site' in schizophrenia: d-serine, glycine, and beyond. Curr Opin Pharmacol. 2015; 20:109-115.
-
(2015)
Curr Opin Pharmacol.
, vol.20
, pp. 109-115
-
-
Balu, D.T.1
Coyle, J.T.2
-
20
-
-
84863550158
-
A multicenter, add-on randomized controlled trial of low-dose d-serine for negative and cognitive symptoms of schizophrenia
-
Weiser M, Heresco-Levy U, Davidson M, et al. A multicenter, add-on randomized controlled trial of low-dose d-serine for negative and cognitive symptoms of schizophrenia. J Clin Psychiatry. 2012;73:e728-e734.
-
(2012)
J Clin Psychiatry.
, vol.73
, pp. e728-e734
-
-
Weiser, M.1
Heresco-Levy, U.2
Davidson, M.3
-
21
-
-
0032403626
-
D-Serine added to antipsychotics for the treatment of schizophrenia
-
Tsai G, Yang P, Chung LC, et al. d-Serine added to antipsychotics for the treatment of schizophrenia. Biol Psychiatry. 1998;44:1081-1089.
-
(1998)
Biol Psychiatry.
, vol.44
, pp. 1081-1089
-
-
Tsai, G.1
Yang, P.2
Chung, L.C.3
-
23
-
-
84990876716
-
Low d-serine levels in schizophrenia: A systematic review and meta-analysis
-
Cho SE, Na KS, Cho SJ, et al. Low d-serine levels in schizophrenia: a systematic review and meta-analysis. Neurosci Lett. 2016;634:42-51.
-
(2016)
Neurosci Lett.
, vol.634
, pp. 42-51
-
-
Cho, S.E.1
Na, K.S.2
Cho, S.J.3
-
24
-
-
84933522572
-
D-Serine for the treatment of negative symptoms in individuals at clinical high risk of schizophrenia: A pilot, double-blind, placebo-controlled, randomised parallel group mechanistic proof-of-concept trial
-
Kantrowitz JT, Woods SW, Petkova E, et al. d-Serine for the treatment of negative symptoms in individuals at clinical high risk of schizophrenia: a pilot, double-blind, placebo-controlled, randomised parallel group mechanistic proof-of-concept trial. Lancet Psychiatry. 2015;2:403-412.
-
(2015)
Lancet Psychiatry.
, vol.2
, pp. 403-412
-
-
Kantrowitz, J.T.1
Woods, S.W.2
Petkova, E.3
-
25
-
-
85015366464
-
Improvement in mismatch negativity generation during d-serine treatment in schizophrenia: Correlation with symptoms [Epub ahead of print March 17, 2017]
-
Kantrowitz JT, Epstein ML, Lee M, et al. Improvement in mismatch negativity generation during d-serine treatment in schizophrenia: correlation with symptoms [Epub ahead of print March 17, 2017]. Schizophr Res. 2017. doi: 10. 1016/j. schres. 2017. 02. 027.
-
(2017)
Schizophr Res.
-
-
Kantrowitz, J.T.1
Epstein, M.L.2
Lee, M.3
-
26
-
-
85010970290
-
Neurophysiological mechanisms of cortical plasticity impairments in schizophrenia and modulation by the NMDA receptor agonist d-serine
-
Kantrowitz JT, Epstein ML, Beggel O, et al. Neurophysiological mechanisms of cortical plasticity impairments in schizophrenia and modulation by the NMDA receptor agonist d-serine. Brain. 2016;139(Pt 12):3281-3295.
-
(2016)
Brain.
, vol.139
, pp. 3281-3295
-
-
Kantrowitz, J.T.1
Epstein, M.L.2
Beggel, O.3
-
31
-
-
0038266756
-
Chlorpromazine equivalent doses for the newer atypical antipsychotics
-
Woods SW. Chlorpromazine equivalent doses for the newer atypical antipsychotics. J Clin Psychiatry. 2005;64:663-667.
-
(2005)
J Clin Psychiatry.
, vol.64
, pp. 663-667
-
-
Woods, S.W.1
-
32
-
-
84939798927
-
Auditory dysfunction in schizophrenia: Integrating clinical and basic features
-
Javitt DC, Sweet RA. Auditory dysfunction in schizophrenia: integrating clinical and basic features. Nat Rev Neurosci. 2015;16:535-550.
-
(2015)
Nat Rev Neurosci.
, vol.16
, pp. 535-550
-
-
Javitt, D.C.1
Sweet, R.A.2
-
33
-
-
85006049219
-
Efficacy and safety of the glycine transporter type-1 inhibitor AMG 747 for the treatment of negative symptoms associated with schizophrenia
-
Dunayevich E, Buchanan RW, Chen CY, et al. Efficacy and safety of the glycine transporter type-1 inhibitor AMG 747 for the treatment of negative symptoms associated with schizophrenia. Schizophr Res. 2017;182: 90-97.
-
(2017)
Schizophr Res.
, vol.182
, pp. 90-97
-
-
Dunayevich, E.1
Buchanan, R.W.2
Chen, C.Y.3
-
34
-
-
84896404591
-
The selective glycine uptake inhibitor org 25935 as an adjunctive treatment to atypical antipsychotics in predominant persistent negative symptoms of schizophrenia: Results from the giant trial
-
Schoemaker JH, Jansen WT, Schipper J, et al. The selective glycine uptake inhibitor org 25935 as an adjunctive treatment to atypical antipsychotics in predominant persistent negative symptoms of schizophrenia: results from the giant trial. J Clin Psychopharmacol. 2014;34:190-198.
-
(2014)
J Clin Psychopharmacol.
, vol.34
, pp. 190-198
-
-
Schoemaker, J.H.1
Jansen, W.T.2
Schipper, J.3
-
35
-
-
15944428993
-
Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: Implications for mechanisms of action
-
Javitt DC, Duncan L, Balla A, et al. Inhibition of system A-mediated glycine transport in cortical synaptosomes by therapeutic concentrations of clozapine: implications for mechanisms of action. Mol Psychiatry. 2005; 10:275-287.
-
(2005)
Mol Psychiatry.
, vol.10
, pp. 275-287
-
-
Javitt, D.C.1
Duncan, L.2
Balla, A.3
|