Severity and features of frailty in systemic sclerosis-associated interstitial lung disease

Respiratory Medicine

Volumn 129, Issue , 2017, Pages 1-7

  Guler, Sabina A ^a   Kwan, Joanne M ^a   Winstone, Tiffany A ^a   Milne, Kathryn M ^a   Dunne, James V ^a   Wilcox, Pearce G ^a   Ryerson, Christopher J ^a  

^a UNIVERSITY OF BRITISH COLUMBIA   (Canada)

Author keywords

Dyspnea; Frailty; Frailty index; Interstitial lung disease; Pulmonary fibrosis; Systemic sclerosis

Indexed keywords

AZATHIOPRINE; CALCIUM CHANNEL BLOCKING AGENT; CYCLOPHOSPHAMIDE; DOMPERIDONE; HYDROXYCHLOROQUINE; MYCOPHENOLATE MOFETIL; PREDNISONE; PROTON PUMP INHIBITOR; RITUXIMAB;

ADULT; AGED; ARTICLE; CLINICAL FEATURE; COHORT ANALYSIS; DISEASE ASSESSMENT; DISEASE SEVERITY; DYSPHAGIA; DYSPNEA; FATIGUE; FEMALE; FORCED EXPIRATORY VOLUME; FORCED VITAL CAPACITY; FRAILTY; FRAILTY INDEX; GASTROESOPHAGEAL REFLUX; HUMAN; INTERSTITIAL LUNG DISEASE; LUNG DIFFUSION CAPACITY; LUNG FIBROSIS; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; OXYGEN THERAPY; PREVALENCE; PRIORITY JOURNAL; PULMONARY HYPERTENSION; RAYNAUD PHENOMENON; SYSTEMIC SCLEROSIS; COMORBIDITY; COMPARATIVE STUDY; COMPLICATION; DIAGNOSTIC IMAGING; LUNG; LUNG FUNCTION TEST; PATHOPHYSIOLOGY; PROCEDURES; SEVERITY OF ILLNESS INDEX; VITAL CAPACITY;

AGED; COMORBIDITY; DYSPNEA; FEMALE; FORCED EXPIRATORY VOLUME; FRAILTY; HUMANS; LUNG; LUNG DISEASES, INTERSTITIAL; MALE; MIDDLE AGED; PREVALENCE; PULMONARY FIBROSIS; RESPIRATORY FUNCTION TESTS; SCLERODERMA, SYSTEMIC; SEVERITY OF ILLNESS INDEX; VITAL CAPACITY;

EID: 85019992051     PISSN: 09546111     EISSN: 15323064     Source Type: Journal    
DOI: 10.1016/j.rmed.2017.05.012     Document Type: Article

References (35)

1. Steen, V.D., Medsger, T.A., Changes in causes of death in systemic sclerosis, 1972-2002. Ann. Rheum. Dis. 66:7 (2007), 940–944.
2. Walker, U.A., Tyndall, A., Czirjak, L., Denton, C., Farge-Bancel, D., Kowal-Bielecka, O., et al. Clinical risk assessment of organ manifestations in systemic sclerosis: a report from the EULAR Scleroderma Trials and Research group database. Ann. Rheum. Dis. 66:6 (2007), 754–763.
3. Rockwood, K., Fox, R.A., Stolee, P., Robertson, D., Beattie, B.L., Frailty in elderly people: an evolving concept. CMAJ, Can. Med. Assoc. J. J. de l'Assoc. Med. Can. 150:4 (1994), 489–495.
4. Rockwood, M.R., MacDonald, E., Sutton, E., Rockwood, K., Baron, M., Frailty index to measure health status in people with systemic sclerosis. J. Rheumatol. 41:4 (2014), 698–705.
5. Milne, K.M., Kwan, J.M., Guler, S., Winstone, T.A., Le, A., Khalil, N., et al. Frailty is common and strongly associated with dyspnoea severity in fibrotic interstitial lung disease. Respirology 22:4 (2017 May), 728–734, 10.1111/resp.12944 Epub 2016 Nov 9.
6. van den Hoogen, F., Khanna, D., Fransen, J., Johnson, S.R., Baron, M., Tyndall, A., et al. 2013 classification criteria for systemic sclerosis: an american college of rheumatology/european league against rheumatism collaborative initiative. Arthritis Rheum. 65:11 (2013), 2737–2747.
7. Raghu, G., Collard, H.R., Egan, J.J., Martinez, F.J., Behr, J., Brown, K.K., et al. An official ATS/ERS/JRS/ALAT statement: idiopathic pulmonary fibrosis: evidence-based guidelines for diagnosis and management. Am. J. Respir. Crit. Care Med. 183:6 (2011), 788–824.
8. Rockwood, K., Song, X., Mitnitski, A., Changes in relative fitness and frailty across the adult lifespan: evidence from the Canadian national population health survey. CMAJ. Can. Med. Assoc. J. = J. de l'Assoc. Med Can. 183:8 (2011), E487–E494.
9. Mitnitski, A.B., Mogilner, A.J., Rockwood, K., Accumulation of deficits as a proxy measure of aging. Sci. World J. 1 (2001), 323–336.
10. Hoover, M., Rotermann, M., Sanmartin, C., Bernier, J., Validation of an index to estimate the prevalence of frailty among community-dwelling seniors. Health Rep. 24:9 (2013), 10–17.
11. Rockwood, K., Mitnitski, A., Limits to deficit accumulation in elderly people. Mech. Ageing Dev. 127:5 (2006), 494–496.
12. Eakin, E.G., Resnikoff, P.M., Prewitt, L.M., Ries, A.L., Kaplan, R.M., Validation of a New Dyspnea Measure: The UCSD Shortness of Breath Questionnaire., 113(3), 1998, 619–624 University of California, San Diego. Chest.
13. Macintyre, N., Crapo, R.O., Viegi, G., Johnson, D.C., van der Grinten, C.P., Brusasco, V., et al. Standardisation of the single-breath determination of carbon monoxide uptake in the lung. Eur. Respir. J. 26:4 (2005), 720–735.
14. Miller, M.R., Hankinson, J., Brusasco, V., Burgos, F., Casaburi, R., Coates, A., et al. Standardisation of spirometry. Eur. Respir. J. 26:2 (2005), 319–338.
15. Wanger, J., Clausen, J.L., Coates, A., Pedersen, O.F., Brusasco, V., Burgos, F., et al. Standardisation of the measurement of lung volumes. Eur. Respir. J. 26:3 (2005), 511–522.
16. ATS statement: guidelines for the six-minute walk test. Am. J. Respir. Crit. Care Med. 166:1 (2002), 111–117.
17. Enright, P.L., Sherrill, D.L., Reference equations for the six-minute walk in healthy adults. Am. J. Respir. Crit. Care Med. 158:5 Pt 1 (1998), 1384–1387.
18. Ryerson, C.J., Vittinghoff, E., Ley, B., Lee, J.S., Mooney, J.J., Jones, K.D., et al. Predicting survival across chronic interstitial lung disease: the ILD-GAP model. Chest 145:4 (2014), 723–728.
19. Navaratnam, V., Ali, N., Smith, C.J., McKeever, T., Fogarty, A., Hubbard, R.B., Does the presence of connective tissue disease modify survival in patients with pulmonary fibrosis?. Respir. Med. 105:12 (2011), 1925–1930.
20. Wells, A.U., Desai, S.R., Rubens, M.B., Goh, N.S., Cramer, D., Nicholson, A.G., et al. Idiopathic pulmonary fibrosis: a composite physiologic index derived from disease extent observed by computed tomography. Am. J. Respir. Crit. Care Med. 167:7 (2003), 962–969.
21. Ryerson, C.J., O'Connor, D., Dunne, J.V., Schooley, F., Hague, C.J., Murphy, D., et al. Predicting mortality in systemic sclerosis-associated interstitial lung disease using risk prediction models derived from idiopathic pulmonary fibrosis. Chest 148:5 (2015), 1268–1275.
22. Denton, C.P., Cailes, J.B., Phillips, G.D., Wells, A.U., Black, C.M., Bois, R.M., Comparison of Doppler echocardiography and right heart catheterization to assess pulmonary hypertension in systemic sclerosis. Br. J. Rheumatol 36:2 (1997), 239–243.
23. Fried, L.P., Tangen, C.M., Walston, J., Newman, A.B., Hirsch, C., Gottdiener, J., et al. Frailty in older adults: evidence for a phenotype. The journals of gerontology Series A. Biol. Sci. Med. Sci. 56:3 (2001), M146–M156.
24. Bergman, H., Ferrucci, L., Guralnik, J., Hogan, D.B., Hummel, S., Karunananthan, S., et al. Frailty: an emerging research and clinical paradigm–issues and controversies. the journals of gerontology Series A. Biol. Sci. Med. Sci. 62:7 (2007), 731–737.
25. Rockwood, K., Mitnitski, A., Frailty defined by deficit accumulation and geriatric medicine defined by frailty. Clin. Geriatr. Med. 27:1 (2011), 17–26.
26. Tyndall, A.J., Bannert, B., Vonk, M., Airo, P., Cozzi, F., Carreira, P.E., et al. Causes and risk factors for death in systemic sclerosis: a study from the EULAR Scleroderma Trials and Research (EUSTAR) database. Ann. Rheum. Dis. 69:10 (2010), 1809–1815.
27. Fulop, T., Larbi, A., Witkowski, J.M., McElhaney, J., Loeb, M., Mitnitski, A., et al. Aging, frailty and age-related diseases. Biogerontology 11:5 (2010), 547–563.
28. Collard, R.M., Boter, H., Schoevers, R.A., Oude Voshaar, R.C., Prevalence of frailty in community-dwelling older persons: a systematic review. J. Am. Geriatr. Soc. 60:8 (2012), 1487–1492.
29. Mitnitski, A.B., Graham, J.E., Mogilner, A.J., Rockwood, K., Frailty, fitness and late-life mortality in relation to chronological and biological age. BMC Geriatr., 2, 2002, 1.
30. Park, S.K., Richardson, C.R., Holleman, R.G., Larson, J.L., Frailty in people with COPD, using the national health and nutrition evaluation survey dataset (2003-2006). Heart & Lung J. Crit. Care 42:3 (2013), 163–170.
31. Holland, A.E., Fiore, J.F. Jr., Bell, E.C., Goh, N., Westall, G., Symons, K., et al. Dyspnoea and comorbidity contribute to anxiety and depression in interstitial lung disease. Respirol. Carlt. Vic. 19:8 (2014), 1215–1221.
32. Delgado, C., Doyle, J.W., Johansen, K.L., Association of frailty with body composition among patients on hemodialysis. J. Ren. Nutr. Off. J. Counc. Ren. Nutr. Natl. Kidney Found. 23:5 (2013), 356–362.
33. Studenski, S.A., Peters, K.W., Alley, D.E., Cawthon, P.M., McLean, R.R., Harris, T.B., et al. The FNIH sarcopenia project: rationale, study description, conference recommendations, and final estimates. J. Gerontol. Ser. A, Biol. Sci. Med. Sci. 69:5 (2014), 547–558.
34. Hubbard, R.E., O'Mahony, M.S., Savva, G.M., Calver, B.L., Woodhouse, K.W., Inflammation and frailty measures in older people. J. Cell. Mol. Med. 13:9b (2009), 3103–3109.
35. Singer, J.P., Diamond, J.M., Gries, C.J., McDonnough, J., Blanc, P.D., Shah, R., et al. Frailty phenotypes, disability, and outcomes in adult candidates for lung transplantation. Am. J. Respir. Crit. Care Med. 192:11 (2015), 1325–1334.