Measuring Appropriate Antimicrobial Use: Attempts at Opening the Black Box

Clinical Infectious Diseases

Volumn 63, Issue 12, 2016, Pages 1-6

  Spivak, Emily S ^a   Cosgrove, Sara E ^b   Srinivasan, Arjun ^c  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

^c NATIONAL CENTER FOR EMERGING AND ZOONOTIC INFECTIOUS DISEASES   (United States)

Author keywords

antibiotic; antimicrobial stewardship; drug resistance; quality; utilization

Indexed keywords

ANTIINFECTIVE AGENT;

ANTIBIOTIC RESISTANCE; DRUG UTILIZATION REVIEW; HUMAN; INAPPROPRIATE PRESCRIBING; PRESCRIPTION; STANDARDS;

ANTI-INFECTIVE AGENTS; DRUG PRESCRIPTIONS; DRUG RESISTANCE, MICROBIAL; DRUG UTILIZATION REVIEW; HUMANS; INAPPROPRIATE PRESCRIBING;

EID: 85019970125     PISSN: 10584838     EISSN: 15376591     Source Type: Journal    
DOI: 10.1093/cid/ciw658     Document Type: Article

References (40)

1. Magill SS, Edwards JR, Beldavs ZG, et al. Prevalence of antimicrobial use in US acute care hospitals, May-September 2011. JAMA 2014; 312:1438-46.
2. van de Sande-Bruinsma N, Grundmann H, Verloo D, et al. Antimicrobial drug use and resistance in Europe. Emerging Infect Dis 2008; 14:1722-30.
3. Fridkin S, Baggs J, Fagan R, et al. Vital signs: improving antibiotic use among hospitalized patients. MMWR Morb Mortal Wkly Rep 2014; 63:194-200.
4. The White House. National Strategy for Combating Antibiotic-Resistant Bacteria. Available at: https://www.whitehouse.gov/sites/default/files/docs/carb_national_ strategy.pdf.
5. Scheckler WE, Bennett JV. Antibiotic usage in seven community hospitals. JAMA 1970; 213:264-7.
6. Roberts AW, Visconti JA. The rational and irrational use of systemic antimicrobial drugs. Am J Hosp Pharm 1972; 29:828-34.
7. Kunin CM, Tupasi T, Craig WA. Use of antibiotics. A brief exposition of the problem and some tentative solutions. Ann Intern Med 1973; 79:555-60.
8. Kollef MH, Sherman G, Ward S, Fraser VJ. Inadequate antimicrobial treatment of infections: a risk factor for hospital mortality among critically ill patients. Chest 1999; 115:462-74.
9. Micek ST, Lloyd AE, Ritchie DJ, Reichley RM, Fraser VJ, Kollef MH. Pseudomonas aeruginosa bloodstream infection: importance of appropriate initial antimicrobial treatment. Antimicrob Agents Chemother 2005; 49:1306-11.
10. Fraser A, Paul M, Almanasreh N, et al. Benefit of appropriate empirical antibiotic treatment: thirty-day mortality and duration of hospital stay. Am J Med 2006; 119:970-6.
11. Ciccolini M, Spoorenberg V, Geerlings SE, Prins JM, Grundmann H. Using an index-based approach to assess the population-level appropriateness of empirical antibiotic therapy. J Antimicrob Chemother 2015; 70:286-93.
12. Seaton RA, Nathwani D, Burton P, et al. Point prevalence survey of antibiotic use in Scottish hospitals utilising the Glasgow Antimicrobial Audit Tool (GAAT). Int J Antimicrob Agents 2007; 29:693-9.
13. Kumar A, Ellis P, Arabi Y, et al. Initiation of inappropriate antimicrobial therapy results in a fivefold reduction of survival in human septic shock. Chest 2009; 136:1237-48.
14. Gómez J, Conde Cavero SJ, Hernández Cardona JL, et al. The influence of the opinion of an infectious disease consultant on the appropriateness of antibiotic treatment in a general hospital. J Antimicrob Chemother 1996; 38:309-14.
15. Parta M, Goebel M, Thomas J, Matloobi M, Stager C, Musher DM. Impact of an assay that enables rapid determination of Staphylococcus species and their drug susceptibility on the treatment of patients with positive blood culture results. Infect Control Hosp Epidemiol 2010; 31:1043-8.
16. Cooke DM, Salter AJ, Phillips I. The impact of antibiotic policy on prescribing in a London teaching hospital: a one-day prevalence survey as an indicator of antibiotic use. J Antimicrob Chemother 1983; 11:447-53.
17. Perez KK, Olsen RJ, Musick WL, et al. Integrating rapid pathogen identification and antimicrobial stewardship significantly decreases hospital costs. Arch Pathol Lab Med 2013; 137:1247-54.
18. Gyssens IC, van den Broek PJ, Kullberg BJ, Hekster Y, van der Meer JW. Optimizing antimicrobial therapy: a method for antimicrobial drug use evaluation. J Anti-microb Chemother 1992; 30:724-7.
19. Raveh D, Levy Y, Schlesinger Y, Greenberg A, Rudensky B, Yinnon AM. Longitudinal surveillance of antibiotic use in the hospital. QJM 2001; 94:141-52.
20. Schwartz DN, Wu US, Lyles RD, et al. Lost in translation? reliability of assessing inpatient antimicrobial appropriateness with use of computerized case vignettes. Infect Control Hosp Epidemiol 2009; 30:163-71.
21. Cotta MO, Robertson MS, Upjohn LM, Marshall C, Liew D, Buising KL. Using periodic point-prevalence surveys to assess appropriateness of antimicrobial prescribing in Australian private hospitals. Intern Med J 2014; 44:240-6.
22. Cisneros JM, Neth O, Gil-Navarro MV, et al. Global impact of an educational antimicrobial stewardship programme on prescribing practice in a tertiary hospital centre. Clin Microbiol Infect 2014; 20:82-8.
23. Akhloufi H, Streefkerk RH, Melles DC, et al. Point prevalence of appropriate antimicrobial therapy in a Dutch university hospital. Eur J Clin Microbiol Infect Dis 2015; 34:1631-7.
24. James R, Upjohn L, Cotta M, et al. Measuring antimicrobial prescribing quality in Australian hospitals: development and evaluation of a national antimicrobial prescribing survey tool. J Antimicrob Chemother 2015; 70:1912-8.
25. Casaroto E, Marra AR, Camargo TZS, et al. Agreement on the prescription of antimicrobial drugs. BMC Infect Dis 2015; 15:248.
26. Vlahovic-Palcevski V, Francetic I, Palcevski G, Novak S, Abram M, Bergman U. Antimicrobial use at a university hospital: appropriate or misused? A qualitative study. Int J Clin Pharmacol Ther 2007; 45:169-74.
27. Osowicki J, Gwee A, Noronha J, et al. Australia-wide point prevalence survey of antimicrobial prescribing in neonatal units: how much and how good? Pediatr Infect Dis J 2015; 34:e185-90.
28. Osowicki J, Gwee A, Noronha J, et al. Australia-wide point prevalence survey of the use and appropriateness of antimicrobial prescribing for children in hospital. Med J Aust 2014; 201:657-62.
29. Peron EP, Hirsch AA, Jury LA, Jump RLP, Donskey CJ. Another setting for stewardship: high rate of unnecessary antimicrobial use in a Veterans Affairs long-term care facility. J Am Geriatr Soc 2013; 61:289-90.
30. van Buul LW, Veenhuizen RB, Achterberg WP, et al. Antibiotic prescribing in Dutch nursing homes: how appropriate is it? J Am Med Dir Assoc 2015; 16:229-37.
31. Willemsen I, Groenhuijzen A, Bogaers D, Stuurman A, van Keulen P, Kluytmans J. Appropriateness of antimicrobial therapy measured by repeated prevalence surveys. Antimicrob Agents Chemother 2007; 51:864-7.
32. Zimmer JG, Bentley DW, Valenti WM, Watson NM. Systemic antibiotic use in nursing homes: a quality assessment. J Am Geriatr Soc 1986; 34:703-10.
33. Filice GA, Drekonja DM, Thurn JR, Hamann GM, Masoud BT, Johnson JR. Diagnostic errors that lead to inappropriate antimicrobial use. Infect Control Hosp Epidemiol 2015; 36:949-56.
34. Schultz L, Lowe TJ, Srinivasan A, Neilson D, Pugliese G. Economic impact of redundant antimicrobial therapy in US hospitals. Infect Control Hosp Epidemiol 2014; 35:1229-35.
35. Drekonja DM, Okoye NC, Kuskowski MA, Johnson JR. Appropriateness of urinary tract infection diagnosis and treatment duration. Arch Intern Med 2010; 170:489-90.
36. Zarb P, Goossens H. European Surveillance of Antimicrobial Consumption (ESAC): value of a point-prevalence survey of antimicrobial use across Europe. Drugs 2011; 71:745-55.
37. DePestel DD, Eiland EH, Lusardi K, et al. Assessing appropriateness of antimicrobial therapy: in the eye of the interpreter. Clin Infect Dis 2014; 59(suppl 3):S154-61.
38. Ansari F, Erntell M, Goossens H, Davey P. The European surveillance of antimicrobial consumption (ESAC) point-prevalence survey of antibacterial use in 20 European hospitals in 2006. Clin Infect Dis 2009; 49:1496-504.
39. Australian Commission on Safety and Quality in Health Care. Antimicrobial Stewardship Initiative. Available at: http://www.safetyandquality.gov.au/our-work/healthcare-associated-infection/antimicrobial-stewardship/. Accessed 26 February 2016.
40. Australian Commission on Safety and Quality in Health Care. Antimicrobial prescribing practice in Australian hospitals. Sydney: 2015. Available at: http://www. safetyandquality.gov.au/wp-content/uploads/2015/07/Antimicrobial-prescribing-practice-in-Aust-hospitals-NAPS-2014-Results.pdf. Accessed 26 February 2016.