Evaluation of a computerized decision support intervention to decrease use of anti-pseudomonal carbapenems in penicillin allergic patients

Antibiotics

Volumn 5, Issue 1, 2016, Pages

  Caplinger, Christina ^a   Smith, Garret ^a   Remington, Richard ^a   Madaras Kelly, Karl ^b  

^a Boise VA Medical Center   (United States)

^b IDAHO STATE UNIVERSITY   (United States)

Author keywords

Antimicrobial stewardship; Antipseudomonal; Carbapenem; Computerized decision support system; lactam allergy; lactam cross reactivity

Indexed keywords

CARBAPENEM; CEFEPIME; CEPHALOSPORIN; CILASTATIN; IMIPENEM; IMMUNOGLOBULIN E; MEROPENEM;

AGED; ARTICLE; CLINICAL DECISION MAKING; CLINICAL EVALUATION; CONTROLLED STUDY; CROSS REACTION; DECISION SUPPORT SYSTEM; FEMALE; FLUSHING; HOSPITALIZATION; HUMAN; HYPOTENSION; MAJOR CLINICAL STUDY; MALE; PENICILLIN ALLERGY; PRESCRIPTION; PRIORITY JOURNAL; RETROSPECTIVE STUDY; THROAT TIGHTNESS; URTICARIA; WHEEZING;

EID: 85019817318     PISSN: None     EISSN: 20796382     Source Type: Journal    
DOI: 10.3390/antibiotics5010007     Document Type: Article

References (33)

1. Kanj, S. S.; Kanafani, Z. A. Current concepts in antimicrobial therapy against resistant gram-negative organisms: Extended-spectrum β-lactamase-producing Enterobacteriaceae, carbapenem-resistant Enterobacteriaceae, and multidrug-resistant Pseudomonas aeruginosa. Mayo Clin. Proc. 2011, 86, 250-259. [CrossRef] [PubMed].
2. Gilbert, D. N.; Moellering, R. C.; Eliopoulos, G. M.; Chambers, H. F.; Saag, M. S. The Sanford Guide to Antimicrobial Therapy 2013; Antimicrobial Therapy, Inc.: Sperryville, VA, USA, 2013.
3. Pakyz, A. L.; Macdougall, C.; Oinonen, M.; Polk, R. E. Trends in antibacterial use in US academic health centers: 2002 to 2006. Arch Intern. Med. 2008, 168, 2254-2260. [CrossRef] [PubMed].
4. Centers for Disease Control and Prevention (CDC). Antibiotic Resistance Threats in the United States; U. S. Department of Health and Human Services: Atlanta, GA, USA, 2013. Available online: http://www. cdc. gov/drugresistance/pdf/ar-threats-2013-508. pdf (accessed on 4 May 2015).
5. Falagas, M. E.; Tansarli, G. S.; Karageorgopoulos, D. E.; Vardakas, K. Z. Deaths attributable to carbapenem-resistant Enterobacteriaceae infections. Emerg. Infect. Dis. 2014, 20, 1170-1175. [CrossRef] [PubMed].
6. Neidell, M. J.; Cohen, B.; Furuya, Y.; Hill, J.; Jeon, C. Y.; Glied, S.; Larson, E. L. Costs of healthcare-and community-associated infections with antimicrobial-resistant versus antimicrobial-susceptible organisms. Clin. Infect. Dis. 2012, 55, 807-815. [CrossRef] [PubMed].
7. Centers for Disease Control and Prevention. 2012 CRE Toolkit-Guidance for Control of Carbapenem-resistant Enterobacteraciae. CDC: Atlanta, GA, USA, 2012. Available online: http://www. cdc. gov/hai/organisms/cre/cre-toolkit/index. html (accessed on 6 May 2015).
8. Dellit, T. H.; Owens, R. C.; McGowan, J. E., Jr.; Gerding, D. N.; Weinstein, R. A.; Burke, J. P.; Huskins, W. C.; Paterson, D. L.; Fishman, N. O.; Carpenter, C. F.; et al. Infectious Diseases Society of America; Society for Healthcare Epidemiology of America. Infectious Diseases Society of America and the Society for Healthcare Epidemiology of America guidelines for developing an institutional program to enhance antimicrobial stewardship. Clin. Infect. Dis. 2007, 44, 159-177. [PubMed].
9. Forrest, G. N.; van Schooneveld, T. C.; Kullar, R.; Schulz, L. T.; Duong, P.; Postelnick, M. Use of electronic health records and clinical decision support systems for antimicrobial stewardship. Clin. Infect. Dis. 2014, 59, S122-S133. [CrossRef] [PubMed].
10. Fox, S.; Park, M. A. Penicillin skin testing in the evaluation and management of penicillin allergy. Ann. Allergy Asthma Immunol. 2011, 106. [CrossRef] [PubMed].
11. Joint Task Force on Practice Parameters; American Academy of Allergy, Asthma and Immunology; American College of Allergy, Asthma and Immunology; Joint Council of Allergy, Asthma and Immunology. Drug allergy: An updated practice parameter. Ann. Allergy Asthma Immunol. 2010, 105, 259-273.
12. Torres, M. J.; Blanca, M. The complex clinical picture of beta-lactam hypersensitivity: Penicillins, cephalosporins, monobactams, carbapenems, and clavams. Med. Clin. North Am. 2010, 94, 805-820. [CrossRef] [PubMed].
13. Pre-Pen [Package Insert]; AllerQuest: Plainville, CT, USA, 2013.
14. Gonzalez-estrada, A.; Radojicic, C. Penicillin allergy: A practical guide for clinicians. Cleve Clin. J. Med. 2015, 82, 295-300. [PubMed].
15. Romano, A.; Viola, M.; Guéant-rodriguez, R. M.; Gaeta, F.; Valluzzi, R.; Guéant, J. L. Brief communication: Tolerability of meropenem in patients with IgE-mediated hypersensitivity to penicillins. Ann. Intern. Med. 2007, 146, 266-269. [CrossRef] [PubMed].
16. Wall, G. C.; Peters, L.; Leaders, C. B.; Wille, J. A. Pharmacist-managed service providing penicillin allergy skin tests. Am. J. Health Syst. Pharm. 2004, 61, 1271-1275. [PubMed].
17. Addison, J.; Whitcombe, J.; William Glover, S. How doctors make use of online, point-of-care clinical decision support systems: A case study of UpToDate©. Health Inf. Libr. J. 2013, 30, 13-22. [CrossRef] [PubMed].
18. UpToDate. Editorial Policy. 2014. Available online: http://www. uptodate. com/home/editorial-policy (accessed on 27 April 2015).
19. Abbo, L. M.; Cosgrove, S. E.; Pottinger, P. S.; Pereyra, M.; Sinkowitz-Cochran, R.; Srinivasan, A.; Webb, D. J.; Hooton, T. M. Medical students' perceptions and knowledge about antimicrobial stewardship: How are we educating our future prescribers? Clin. Infect. Dis. 2013, 57, 631-638. [CrossRef] [PubMed].
20. Solensky, R. Penicillin-Allergic Patients: Use of Cephalosporins, Carbapenems, and Monobactams. UpToDate. Available online: http://www. uptodate. com/contents/penicillin-allergic-patients-use-ofcephalosporins-carbapenems-and-monobactams (accessed on 18 March 2015).
21. Unger, N. R.; Gauthier, T. P.; Cheung, L. W. Penicillin skin testing: Potential implications for antimicrobial stewardship. Pharmacotherapy 2013, 33, 856-867. [CrossRef] [PubMed].
22. Frumin, J.; Gallagher, J. C. Allergic cross-sensitivity between penicillin, carbapenem, and monobactam antibiotics: What are the chances? Ann. Pharmacother. 2009, 43, 304-315. [PubMed].
23. Dudley, M. N.; Ambrose, P. G.; Bhavnani, S. M.; Craig, W. A.; Ferraro, M. J.; Jones, R. N.; Antimicrobial Susceptibility Testing Subcommittee of the Clinical and Laboratory Standards Institute. Background and rationale for revised clinical and laboratory standards institute interpretive criteria (Breakpoints) for Enterobacteriaceae and Pseudomonas aeruginosa: I. Cephalosporins and Aztreonam. Clin. Infect. Dis. 2013, 56, 1301-1309. [PubMed].
24. National Center for Health Statistics. Health, United States, 2014: With Special Feature on Adults Aged 55-64; Centers for Disease Control and Prevention: Hyattsville, MD, USA, 2015. Available online: http://www. cdc. gov/nchs/data/hus/hus14. pdf (accessed on 6 May 2015).
25. Pakyz, A. L.; Oinonen, M.; Polk, R. E. Relationship of carbapenem restriction in 22 university teaching hospitals to carbapenem use and carbapenem-resistant Pseudomonas aeruginosa. Antimicrob. Agents Chemother. 2009, 53, 1983-1986. [CrossRef] [PubMed].
26. Kaki, R.; Elligsen, M.; Walker, S.; Simor, A.; Palmay, L.; Daneman, N. Impact of antimicrobial stewardship in critical care: A systematic review. J. Antimicrob. Chemother. 2011, 66, 1223-1230. [CrossRef] [PubMed].
27. Carmeli, Y.; Troillet, N.; Eliopoulos, G. M.; Samore, M. H. Emergence of antibiotic-resistant Pseudomonas aeruginosa: Comparison of risks associated with different antipseudomonal agents. Antimicrob. Agents Chemother. 1999, 43, 1379-1382. [PubMed].
28. Wagner, A. K.; Soumerai, S. B.; Zhang, F.; Ross-Degnan, D. Segmented regression analysis of interrupted time series studies in medication use research. J. Clin. Pharm. Ther. 2002, 27, 299-309. [CrossRef] [PubMed].
29. Miranda, A.; Blanca, M.; Vega, J. M.; Moreno, F.; Carmona, M. J.; García, J. J.; Segurado, E.; Justicia, J. L.; Juarez, C. Cross-reactivity between a penicillin and a cephalosporin with the same side chain. J. Allergy Clin. Immunol. 1996, 98, 671-677. [CrossRef].
30. Davey, P.; Brown, E.; Charani, E.; Fenelon, L.; Gould, I. M.; Holmes, A.; Ramsay, C. R.; Wiffen, P. J.; Wilcox, M. Interventions to improve antibiotic prescribing practices for hospital inpatients. Cochrane Database Syst. Rev. 2013, 30. [CrossRef].
31. Kullar, R.; Goff, D. A. Transformation of antimicrobial stewardship programs through technology and informatics. Infect. Dis. Clin. North Am. 2014, 28, 291-300. [CrossRef] [PubMed].
32. Harris, A. D.; Bradham, D. D.; Baumgarten, M.; Zuckerman, I. H.; Fink, J. C.; Perencevich, E. N. The use and interpretation of quasi-experimental studies in infectious diseases. Clin. Infect. Dis. 2004, 38, 1586-1591. [PubMed].
33. Rimawi, R. H.; Cook, P. P.; Gooch, M.; Kabchi, B.; Ashraf, M. S.; Rimawi, B. H.; Gebregziabher, M.; Siraj, D. S. The impact of penicillin skin testing on clinical practice and antimicrobial stewardship. J. Hosp. Med. 2013, 8, 341-345. [CrossRef] [PubMed].