Cross-reactivity between a penicillin and a cephalosporin with the same side chain

Journal of Allergy and Clinical Immunology

Volumn 98, Issue 3, 1996, Pages 671-677

  Miranda, Alfonso ^a   Blanca, Miguel ^b,c   Vega, Jose M ^a   Moreno, Felisa ^b   Carmona, Maria J ^a   Garcia, Juan J ^a   Segurado, Elisardo ^a   Justicia, Jose L ^a   Juarez, Carlos ^c  

^a Allergy Section   (Spain)

^b Research Unit for Allergic Diseases   (Spain)

^c HOSPITAL REGIONAL UNIVERSITARIO DE MÁLAGA   (Spain)

Author keywords

cephalosporins; cross reactivity; Penicillins; side chain identity

Indexed keywords

AMOXICILLIN; BUTYLAMINE; CEFADROXIL; CEFAMANDOLE; CEPHALOSPORIN DERIVATIVE; IMMUNOGLOBULIN E ANTIBODY; PENICILLIN DERIVATIVE; PENICILLIN G; PENICILLIN V; PHENYLGLYCINE;

ADULT; ANAPHYLAXIS; ARTICLE; CHEMICAL STRUCTURE; CLINICAL ARTICLE; CONTROLLED STUDY; DRUG CROSS REACTIVITY; DRUG HYPERSENSITIVITY; DRUG TOLERANCE; FEMALE; HUMAN; MALE; ORAL DRUG ADMINISTRATION; PRIORITY JOURNAL; RADIOALLERGOSORBENT TEST; SKIN TEST;

EID: 0029914144     PISSN: 00916749     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0091-6749(96)70101-X     Document Type: Article

References (26)

1. Batchelor FR, Dewdney JM, Gazzard D. Penicillin allergy: the formation of the penicilloyl determinant. Nature 1965; 206:362-4.
2. Dewdney JM. Immunology of the antibiotics. In: Sela M, editor. Antigens 5. New York: Academic Press, 1977:73-245.
3. Levine BB, Ovary Z. Studies of the mechanism of the formation of the penicillin antigen III. The N(D-(benzyl penicilloyl) group as an antigenic determinant responsible for hypersensitivity to penicillin G. J Exp Med 1961;114:875-82.
4. Levine BB, Remond AP. Minor haptenic determinant-specific reagins of penicillin hypersensitivity in man. Int Arch Allergy 1969;35:445-55.
5. Batchelor FR, Dewdney M, Weston RD, Wheeler AW. The immunogenicity of cephalosporin derivatives and their cross-reaction with penicillin. Immunology 1966;10:21.
6. Igea JM, Fraj J, Davila I, Cuevas M, Cuesta J, Hinojhosa M. Allergy to cefazolin: study of in vivo cross reactivity with other betalactams. Ann Allergy 1992;68:515-9.
7. Ong R, Sullivan T. Detection and characterization of human IgE to cephalosporin determinants [abstract]. J Allergy Clin Immunol 1988;81:222.
8. Blanca M, Fernández J, Miranda A, et al. Cross-reactivities between penicillins and cephalosporins. Clinical and immunological studies. J Allergy Clin Immunol 1989;83:381-5.
9. Petz LD. Immunologic cross-reactivity between penicillins and cephalosporins. J Infect Dis 1978;137:S74-9.
10. Girard JP. Common antigenic determinants of penicillin G, ampicillin and cephalosporins demonstrated in man. Int Arch Allergy Appl Immunol 1968;33:428-38.
11. Blanca M, Vega JM, García JJ, et al. New aspects of allergic reactions to betalactams: cross-reactions and unique specificities. Clin Exp Allergy 1994;24:407-15.
12. Adkinson NF. Side-chain specific betalactam allergy. Clin Exp Allergy 1990;20:445-7.
13. Blanca M, Vega JM, García J, et al. Allergy to amoxicillin with good tolerance to other penicillins. Study of the incidence in patients allergic to betalactams. Clin Exp Allergy 1991:20:475-81.
14. Gadde J, Spence M, Wheeler B, Adkinson NF. Clinical experience with penicillin skin testing in a large inner-city STD clinic. JAMA 1993;27:2456-63.
15. Norman PS. In vivo methods of study of allergy. Skin tests and mucosal tests, techniques and interpretations. In: Middleton E Jr, Ellis EF, Reed CE, editors. Allergy, principles and practice. 2nd ed. St. Louis: The C.V. Mosby Co, 1983:297.
16. Blanca M, Mayorga C, Pérez E, et al. Determination of IgE antibodies to the benzyl penicilloyl determinant. Comparison between poly-L-lysine and human serum albumin as carriers. J Immunol Methods 1992;153:99-105.
17. Moreno F, Blanca M, Mayorga C, et al. Studies of the specificities of IgE antibodies found in sera from subjects with allergic reactions to penicillins. Int Arch Allergy Appl immunol 1995;108:74-81.
18. Kabin SA, Eisestein B, Cohen S. Anaphylactic reaction to an initial dose of sodium cephalothin. JAMA 1965;193:165.
19. Rothschild PD, Doty DB. Cephalosporin reaction after penicillin sensitization. JAMA 1966;196:372.
20. Abraham GN, Petz LD, Fundenberg HH. Cephalothin hypersensitivity associated with anti-cephalothin antibodies. Int Arch Allergy 1968;34:65-74.
21. Assem ESK, Vickers R. Test for penicillin allergy in man. The immunological cross-reaction between penicillins and cephalosporins. Immunology 1974;27:255.
22. Petersen BH, Graham J. Immunologic cross-reactivity between penicillin and cephalosporin. J Lab Clin Med 1974; 83:860-70.
23. Audicana M, Bernaola G, Urrutia I, et al. Allergic reactions to betalactams: studies in a group of patients allergic to penicillin and evaluation of cross-reactivity with cephalosporin. Allergy 1994;49:108-13.
24. Vega JM, Blanca M, García JJ, et al. Immediate allergic reactions to amoxicillin. Allergy 1994;49:317-22.
25. Quijano D, Novalbos A, Olmo M, et al. Evaluacion de reactividad cruzada entre amoxicilina y cefadroxilo en pacientes alérgicos a la amoxicilina con buena tolerancia a penicilina. Rev Esp Alergol Immun Clin 1994;9:73.
26. Mayorga C, Obispo T, Jimeno L, et al. Epitope mapping of betalactam antibiotics with the use of monoclonal antibodies. Toxicology 1995;97:225-34.