Cardiorespiratory fitness alters the influence of a polygenic risk score on biomarkers of AD

Neurology

Volumn 88, Issue 17, 2017, Pages 1650-1658

  Schultz, Stephanie A ^a,c   Boots, Elizabeth A ^a,c   Darst, Burcu F ^c   Zetterberg, Henrik ^c,d   Blennow, Kaj ^c   Edwards, Dorothy F ^c,e   Koscik, Rebecca L ^c   Carlsson, Cynthia M ^a,c,e   Gallagher, Catherine L ^a,c,e   Bendlin, Barbara B ^a,c,e   Asthana, Sanjay ^a,c,e   Sager, Mark A ^c,e   Hogan, Kirk J ^e   Hermann, Bruce P ^c,e   Cook, Dane B ^b,c   Johnson, Sterling C ^a,c,e   Engelman, Corinne D ^c,f   Okonkwo, Ozioma C ^a,c  

^a GERIATRIC RESEARCH EDUCATION AND CLINICAL CENTER   (United States)

^b WILLIAM S MIDDLETON MEMORIAL VETERANS HOSPITAL   (United States)

^c UNIVERSITY OF WISCONSIN SCHOOL OF MEDICINE AND PUBLIC HEALTH   (United States)

^d Clinical Neurochemistry Laboratory   (Sweden)

^e UNIVERSITY OF GOTHENBURG   (Sweden)

^f UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

ABC TRANSPORTER; AMYLOID BETA PROTEIN[1-40]; AMYLOID BETA PROTEIN[1-42]; APOLIPOPROTEIN E4; ATP BINDING CASSETTE TRANSPORTER A7; BIOLOGICAL MARKER; CLUSTERIN; TAU PROTEIN; UNCLASSIFIED DRUG; ABCA7 PROTEIN, HUMAN; AMYLOID BETA PROTEIN; AMYLOID BETA-PROTEIN (1-42); CLU PROTEIN, HUMAN; MAPT PROTEIN, HUMAN; PEPTIDE FRAGMENT;

ADULT; ADVERSE OUTCOME; AGED; ALZHEIMER DISEASE; ARTICLE; CARDIORESPIRATORY FITNESS; CEREBROSPINAL FLUID; CHOLESTEROL METABOLISM; COHORT ANALYSIS; FEMALE; GENETIC ASSOCIATION; GENETIC RISK; GENETIC SUSCEPTIBILITY; HUMAN; MAJOR CLINICAL STUDY; MALE; POLYGENIC RISK SCORE; PRIORITY JOURNAL; RISK ASSESSMENT; CAUCASIAN; CROSS-SECTIONAL STUDY; GENETICS; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PATHOPHYSIOLOGY; PHOSPHORYLATION; PHYSIOLOGY; REGISTER; RISK; WISCONSIN;

AGED; ALZHEIMER DISEASE; AMYLOID BETA-PEPTIDES; APOLIPOPROTEIN E4; ATP-BINDING CASSETTE TRANSPORTERS; BIOMARKERS; CARDIORESPIRATORY FITNESS; CLUSTERIN; COHORT STUDIES; CROSS-SECTIONAL STUDIES; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; HUMANS; MALE; MIDDLE AGED; MULTIFACTORIAL INHERITANCE; PEPTIDE FRAGMENTS; PHOSPHORYLATION; REGISTRIES; RISK; TAU PROTEINS; WISCONSIN;

EID: 85019790732     PISSN: 00283878     EISSN: 1526632X     Source Type: Journal    
DOI: 10.1212/WNL.0000000000003862     Document Type: Article

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