The Pathogenic Transforming Growth Factor-β Overdrive Hypothesis in Aortic Aneurysms and Dissections: A Mirage?

Circulation Research

Volumn 120, Issue 11, 2017, Pages 1718-1720

  Mallat, Ziad ^a,b   Ait Oufella, Hafid ^b   Tedgui, Alain ^b  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b PARIS CARDIOVASCULAR RESEARCH CENTER   (France)

Author keywords

aneurysm; aorta; aortic dissection; connective tissue; extracellular matrix; losartan

Indexed keywords

SMAD3 PROTEIN; SMAD4 PROTEIN; TRANSFORMING GROWTH FACTOR BETA;

AORTIC DISSECTION; GENE; GENE MUTATION; GENETIC MANIPULATION; GENETIC VARIATION; MARFAN SYNDROME; NONHUMAN; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SIGNAL TRANSDUCTION; TGFB2 GENE; TGFB3 GENE; TGFBR1 GENE; TGFBR2 GENE; THORACIC AORTA ANEURYSM; THORACIC AORTIC DISSECTION; ANIMAL; AORTIC ANEURYSM; DISSECTING ANEURYSM; GENETICS; HUMAN; METABOLISM; MUTATION; PHYSIOLOGY;

ANEURYSM, DISSECTING; ANIMALS; AORTIC ANEURYSM; HUMANS; MARFAN SYNDROME; MUTATION; TRANSFORMING GROWTH FACTOR BETA;

EID: 85019768185     PISSN: 00097330     EISSN: 15244571     Source Type: Journal    
DOI: 10.1161/CIRCRESAHA.116.310371     Document Type: Review

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