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Volumn 69, Issue 21, 2017, Pages 2646-2656

Novel Diabetes Drugs and the Cardiovascular Specialist

Author keywords

blood glucose; cardiovascular disease; heart failure; hypoglycemic agents; outcomes

Indexed keywords

2,4 THIAZOLIDINEDIONE DERIVATIVE; ALOGLIPTIN; ANTIDIABETIC AGENT; DIPEPTIDYL PEPTIDASE IV INHIBITOR; EMPAGLIFLOZIN; EXENDIN 4; GLIBENCLAMIDE; GLIPIZIDE; GLUCAGON LIKE PEPTIDE 1 RECEPTOR AGONIST; HEMOGLOBIN A1C; INSULIN; LIRAGLUTIDE; METFORMIN; PIOGLITAZONE; PLACEBO; ROSIGLITAZONE; SAXAGLIPTIN; SEMAGLUTIDE; SODIUM GLUCOSE COTRANSPORTER 2 INHIBITOR; SULFONYLUREA DERIVATIVE; TOLBUTAMIDE; GLUCOSE BLOOD LEVEL;

EID: 85019611136     PISSN: 07351097     EISSN: 15583597     Source Type: Journal    
DOI: 10.1016/j.jacc.2017.04.014     Document Type: Review
Times cited : (79)

References (53)
  • 1
    • 84891760955 scopus 로고    scopus 로고
    • Cardiovascular outcome studies with novel antidiabetes agents: scientific and operational considerations
    • Hirshberg, B., Katz, A., Cardiovascular outcome studies with novel antidiabetes agents: scientific and operational considerations. Diabetes Care 36:Suppl 2 (2013), S253–S258.
    • (2013) Diabetes Care , vol.36 , pp. S253-S258
    • Hirshberg, B.1    Katz, A.2
  • 2
    • 84944800184 scopus 로고    scopus 로고
    • Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes
    • Zinman, B., Wanner, C., Lachin, J.M., et al., for the EMPA-REG OUTCOME Investigators. Empagliflozin, cardiovascular outcomes, and mortality in type 2 diabetes. N Engl J Med 373 (2015), 2117–2128.
    • (2015) N Engl J Med , vol.373 , pp. 2117-2128
    • Zinman, B.1    Wanner, C.2    Lachin, J.M.3
  • 3
    • 84978839381 scopus 로고    scopus 로고
    • Liraglutide and cardiovascular outcomes in type 2 diabetes
    • Marso, S.P., Daniels, G.H., Brown-Frandsen, K., et al., for the LEADER Steering Committee on behalf of the LEADER Trial Investigators. Liraglutide and cardiovascular outcomes in type 2 diabetes. N Engl J Med 375 (2016), 311–322.
    • (2016) N Engl J Med , vol.375 , pp. 311-322
    • Marso, S.P.1    Daniels, G.H.2    Brown-Frandsen, K.3
  • 4
    • 84994813253 scopus 로고    scopus 로고
    • Semaglutide and cardiovascular outcomes in patients with type 2 diabetes
    • Marso, S.P., Bain, S.C., Consoli, A., et al., for the SUSTAIN-6 Investigators. Semaglutide and cardiovascular outcomes in patients with type 2 diabetes. N Engl J Med 375 (2016), 1834–1844.
    • (2016) N Engl J Med , vol.375 , pp. 1834-1844
    • Marso, S.P.1    Bain, S.C.2    Consoli, A.3
  • 5
    • 0027987849 scopus 로고
    • Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S)
    • Scandinavian Simvastatin Survival Study Group. Randomised trial of cholesterol lowering in 4444 patients with coronary heart disease: the Scandinavian Simvastatin Survival Study (4S). Lancet 344 (1994), 1383–1389.
    • (1994) Lancet , vol.344 , pp. 1383-1389
  • 6
    • 0034688194 scopus 로고    scopus 로고
    • Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators
    • Heart Outcomes Prevention Evaluation Study Investigators. Effects of an angiotensin-converting-enzyme inhibitor, ramipril, on cardiovascular events in high-risk patients. The Heart Outcomes Prevention Evaluation Study Investigators. N Engl J Med 342 (2000), 145–153.
    • (2000) N Engl J Med , vol.342 , pp. 145-153
  • 7
    • 70349881450 scopus 로고    scopus 로고
    • Intensive glucose control and macrovascular outcomes in type 2 diabetes
    • Turnbull, F.M., Abraira, C., Anderson, R.J., et al., for the Control Group. Intensive glucose control and macrovascular outcomes in type 2 diabetes. Diabetologia 52 (2009), 2288–2298.
    • (2009) Diabetologia , vol.52 , pp. 2288-2298
    • Turnbull, F.M.1    Abraira, C.2    Anderson, R.J.3
  • 8
    • 65649106228 scopus 로고    scopus 로고
    • Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials
    • Ray, K.K., Seshasai, S.R.K., Wijesuriya, S., et al. Effect of intensive control of glucose on cardiovascular outcomes and death in patients with diabetes mellitus: a meta-analysis of randomised controlled trials. Lancet 373 (2009), 1765–1772.
    • (2009) Lancet , vol.373 , pp. 1765-1772
    • Ray, K.K.1    Seshasai, S.R.K.2    Wijesuriya, S.3
  • 10
    • 85007353029 scopus 로고    scopus 로고
    • Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: a Bayesian meta-analysis of survival data
    • Bain, S., Druyts, E., Balijepalli, C., et al. Cardiovascular events and all-cause mortality associated with sulphonylureas compared with other antihyperglycaemic drugs: a Bayesian meta-analysis of survival data. Diabetes Obes Metab 19 (2017), 329–335.
    • (2017) Diabetes Obes Metab , vol.19 , pp. 329-335
    • Bain, S.1    Druyts, E.2    Balijepalli, C.3
  • 11
    • 84880656964 scopus 로고    scopus 로고
    • Sulphonylurea monotherapy for patients with type 2 diabetes mellitus
    • Hemmingsen, B., Schroll, J.B., Lund, S.S., et al. Sulphonylurea monotherapy for patients with type 2 diabetes mellitus. Cochrane Database Syst Rev, 4, 2013, CD009008.
    • (2013) Cochrane Database Syst Rev , vol.4 , pp. CD009008
    • Hemmingsen, B.1    Schroll, J.B.2    Lund, S.S.3
  • 12
    • 34250212715 scopus 로고    scopus 로고
    • Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes
    • Nissen, S.E., Wolski, K., Effect of rosiglitazone on the risk of myocardial infarction and death from cardiovascular causes. N Engl J Med 356 (2007), 2457–2471.
    • (2007) N Engl J Med , vol.356 , pp. 2457-2471
    • Nissen, S.E.1    Wolski, K.2
  • 13
    • 84924662049 scopus 로고    scopus 로고
    • Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis
    • Levin, D., Bell, S., Sund, R., et al., for the Scottish Diabetes Research Network Epidemiology Group and the Diabetes and Cancer Research Consortium. Pioglitazone and bladder cancer risk: a multipopulation pooled, cumulative exposure analysis. Diabetologia 58 (2015), 493–504.
    • (2015) Diabetologia , vol.58 , pp. 493-504
    • Levin, D.1    Bell, S.2    Sund, R.3
  • 14
    • 34250865768 scopus 로고    scopus 로고
    • Rosiglitazone evaluated for cardiovascular outcomes—an interim analysis
    • Home, P.D., Pocock, S.J., Beck-Nielsen, H., et al. Rosiglitazone evaluated for cardiovascular outcomes—an interim analysis. N Engl J Med 357 (2007), 28–38.
    • (2007) N Engl J Med , vol.357 , pp. 28-38
    • Home, P.D.1    Pocock, S.J.2    Beck-Nielsen, H.3
  • 15
    • 79953236112 scopus 로고    scopus 로고
    • Thiazolidinediones and risk of heart failure in patients with or at high risk of type 2 diabetes mellitus: a meta-analysis and meta-regression analysis of placebo-controlled randomized clinical trials
    • Hernandez, A.V., Usmani, A., Rajamanickam, A., Moheet, A., Thiazolidinediones and risk of heart failure in patients with or at high risk of type 2 diabetes mellitus: a meta-analysis and meta-regression analysis of placebo-controlled randomized clinical trials. Am J Cardiovasc Drugs 11 (2011), 115–128.
    • (2011) Am J Cardiovasc Drugs , vol.11 , pp. 115-128
    • Hernandez, A.V.1    Usmani, A.2    Rajamanickam, A.3    Moheet, A.4
  • 16
    • 84925266117 scopus 로고    scopus 로고
    • Was there really any evidence that rosiglitazone increased the risk of myocardial infarction or death from cardiovascular causes?
    • Stone, J.C., Furuya-Kanamori, L., Barendregt, J.J., Doi, S.A.R., Was there really any evidence that rosiglitazone increased the risk of myocardial infarction or death from cardiovascular causes?. Pharmacoepidemiol Drug Saf 24 (2015), 223–227.
    • (2015) Pharmacoepidemiol Drug Saf , vol.24 , pp. 223-227
    • Stone, J.C.1    Furuya-Kanamori, L.2    Barendregt, J.J.3    Doi, S.A.R.4
  • 17
    • 26244453309 scopus 로고    scopus 로고
    • Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial
    • Dormandy, J.A., Charbonnel, B., Eckland, D.J.A., et al., for the PROactive Investigators. Secondary prevention of macrovascular events in patients with type 2 diabetes in the PROactive Study (PROspective pioglitAzone Clinical Trial In macroVascular Events): a randomised controlled trial. Lancet 366 (2005), 1279–1289.
    • (2005) Lancet , vol.366 , pp. 1279-1289
    • Dormandy, J.A.1    Charbonnel, B.2    Eckland, D.J.A.3
  • 18
    • 84860375795 scopus 로고    scopus 로고
    • Thiazolidinediones and PPARγ agonists: time for a reassessment
    • Cariou, B., Charbonnel, B., Staels, B., Thiazolidinediones and PPARγ agonists: time for a reassessment. Trends Endocrinol Metab 23 (2012), 205–215.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 205-215
    • Cariou, B.1    Charbonnel, B.2    Staels, B.3
  • 19
    • 84883765959 scopus 로고    scopus 로고
    • Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus
    • Scirica, B.M., Bhatt, D.L., Braunwald, E., et al., for the SAVOR-TIMI 53 Steering Committee and Investigators. Saxagliptin and cardiovascular outcomes in patients with type 2 diabetes mellitus. N Engl J Med 369 (2013), 1317–1326.
    • (2013) N Engl J Med , vol.369 , pp. 1317-1326
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 20
    • 84883745765 scopus 로고    scopus 로고
    • Alogliptin after acute coronary syndrome in patients with type 2 diabetes
    • White, W.B., Cannon, C.P., Heller, S.R., et al., for the EXAMINE Investigators. Alogliptin after acute coronary syndrome in patients with type 2 diabetes. N Engl J Med 369 (2013), 1327–1335.
    • (2013) N Engl J Med , vol.369 , pp. 1327-1335
    • White, W.B.1    Cannon, C.P.2    Heller, S.R.3
  • 21
    • 84937053742 scopus 로고    scopus 로고
    • Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes
    • Green, J.B., Bethel, M.A., Armstrong, P.W., et al., for the TECOS Study Group. Effect of sitagliptin on cardiovascular outcomes in type 2 diabetes. N Engl J Med 373 (2015), 232–242.
    • (2015) N Engl J Med , vol.373 , pp. 232-242
    • Green, J.B.1    Bethel, M.A.2    Armstrong, P.W.3
  • 22
    • 84890568491 scopus 로고    scopus 로고
    • Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a meta-analysis
    • Wu, D., Li, L., Liu, C., Efficacy and safety of dipeptidyl peptidase-4 inhibitors and metformin as initial combination therapy and as monotherapy in patients with type 2 diabetes mellitus: a meta-analysis. Diabetes Obes Metab 16 (2014), 30–37.
    • (2014) Diabetes Obes Metab , vol.16 , pp. 30-37
    • Wu, D.1    Li, L.2    Liu, C.3
  • 23
    • 84994475820 scopus 로고    scopus 로고
    • Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: meta-analysis of placebo-controlled randomized clinical trials
    • Rehman, M.B., Tudrej, B.V., Soustre, J., et al. Efficacy and safety of DPP-4 inhibitors in patients with type 2 diabetes: meta-analysis of placebo-controlled randomized clinical trials. Diabetes Metab 43 (2017), 48–58.
    • (2017) Diabetes Metab , vol.43 , pp. 48-58
    • Rehman, M.B.1    Tudrej, B.V.2    Soustre, J.3
  • 24
    • 85021438535 scopus 로고    scopus 로고
    • Association between sitagliptin use and heart failure hospitalization and related outcomes in type 2 diabetes mellitus: secondary analysis of a randomized clinical trial
    • McGuire, D.K., Van de Werf, F., Armstrong, P.W., et al., for the Trial Evaluating Cardiovascular Outcomes With Sitagliptin (TECOS) Study Group. Association between sitagliptin use and heart failure hospitalization and related outcomes in type 2 diabetes mellitus: secondary analysis of a randomized clinical trial. JAMA Cardiol 1 (2016), 126–135.
    • (2016) JAMA Cardiol , vol.1 , pp. 126-135
    • McGuire, D.K.1    Van de Werf, F.2    Armstrong, P.W.3
  • 25
    • 84864270406 scopus 로고    scopus 로고
    • Basal insulin and cardiovascular and other outcomes in dysglycemia
    • ORIGIN Trial Investigators. Basal insulin and cardiovascular and other outcomes in dysglycemia. N Engl J Med 367 (2012), 319–328.
    • (2012) N Engl J Med , vol.367 , pp. 319-328
  • 26
    • 0032511566 scopus 로고    scopus 로고
    • Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34)
    • UK Prospective Diabetes Study (UKPDS) Group. Effect of intensive blood-glucose control with metformin on complications in overweight patients with type 2 diabetes (UKPDS 34). Lancet 352 (1998), 854–865.
    • (1998) Lancet , vol.352 , pp. 854-865
  • 28
    • 85019618781 scopus 로고    scopus 로고
    • Eli Lilly and Company. EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved).. Available at: Accessed April 5, 2017.
    • Boehringer Ingelheim, Eli Lilly and Company. EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Preserved Ejection Fraction (EMPEROR-Preserved). 2017. Available at: https://clinicaltrials.gov/ct2/show/NCT03057951. Accessed April 5, 2017.
    • (2017)
  • 29
    • 85019538721 scopus 로고    scopus 로고
    • Boehringer Ingelheim, Eli Lilly and Company. EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced). Available at: Accessed April 5.
    • Boehringer Ingelheim, Eli Lilly and Company. EMPagliflozin outcomE tRial in Patients With chrOnic heaRt Failure With Reduced Ejection Fraction (EMPEROR-Reduced). Available at: https://clinicaltrials.gov/ct2/show/NCT03057977. Accessed April 5, 2017.
    • (2017)
  • 30
    • 85019630680 scopus 로고    scopus 로고
    • AstraZeneca announces two new phase IIIb trials for Forxiga in chronic kidney disease and chronic heart failure [press release]. September 12,. Available at: Accessed April 5, 2017.
    • AstraZeneca. AstraZeneca announces two new phase IIIb trials for Forxiga in chronic kidney disease and chronic heart failure [press release]. September 12, 2016. Available at: https://www.astrazeneca.com/media-centre/press-releases/2016/astrazeneca-announces-two-new-phase-IIIb-trials-for-Forxiga-in-chronic-kidney-disease-and-chronic-heart-failure-120920161.html. Accessed April 5, 2017.
    • (2016)
  • 31
    • 84994180780 scopus 로고    scopus 로고
    • Empagliflozin and progression of kidney disease in type 2 diabetes
    • Wanner, C., Inzucchi, S.E., Lachin, J.M., et al., for the EMPA-REG OUTCOME Investigators. Empagliflozin and progression of kidney disease in type 2 diabetes. N Engl J Med 375 (2016), 323–334.
    • (2016) N Engl J Med , vol.375 , pp. 323-334
    • Wanner, C.1    Inzucchi, S.E.2    Lachin, J.M.3
  • 32
    • 84893214045 scopus 로고    scopus 로고
    • Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus
    • Cherney, D.Z.I., Perkins, B.A., Soleymanlou, N., et al. Renal hemodynamic effect of sodium-glucose cotransporter 2 inhibition in patients with type 1 diabetes mellitus. Circulation 129 (2014), 587–597.
    • (2014) Circulation , vol.129 , pp. 587-597
    • Cherney, D.Z.I.1    Perkins, B.A.2    Soleymanlou, N.3
  • 33
    • 84964507777 scopus 로고    scopus 로고
    • SGLT2 inhibition and cardiovascular events: why did EMPA-REG OUTCOMEs surprise and what were the likely mechanisms?
    • Sattar, N., McLaren, J., Kristensen, S.L., Preiss, D., McMurray, J.J., SGLT2 inhibition and cardiovascular events: why did EMPA-REG OUTCOMEs surprise and what were the likely mechanisms?. Diabetologia 59 (2016), 1333–1339.
    • (2016) Diabetologia , vol.59 , pp. 1333-1339
    • Sattar, N.1    McLaren, J.2    Kristensen, S.L.3    Preiss, D.4    McMurray, J.J.5
  • 34
    • 84980320178 scopus 로고    scopus 로고
    • Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications
    • Heerspink, H.J.L., Perkins, B.A., Fitchett, D.H., Husain, M., Cherney, D.Z.I., Sodium glucose cotransporter 2 inhibitors in the treatment of diabetes mellitus: cardiovascular and kidney effects, potential mechanisms, and clinical applications. Circulation 134 (2016), 752–772.
    • (2016) Circulation , vol.134 , pp. 752-772
    • Heerspink, H.J.L.1    Perkins, B.A.2    Fitchett, D.H.3    Husain, M.4    Cherney, D.Z.I.5
  • 35
    • 85015765803 scopus 로고    scopus 로고
    • Sodium-glucose cotransporter-2 inhibition for the reduction of cardiovascular events in high-risk patients with diabetes mellitus
    • Marx, N., McGuire, D.K., Sodium-glucose cotransporter-2 inhibition for the reduction of cardiovascular events in high-risk patients with diabetes mellitus. Eur Heart J 37 (2016), 3192–3200.
    • (2016) Eur Heart J , vol.37 , pp. 3192-3200
    • Marx, N.1    McGuire, D.K.2
  • 36
    • 85006172812 scopus 로고    scopus 로고
    • Effect of empagliflozin on left ventricular mass and diastolic function in individuals with diabetes: an important clue to the EMPA-REG OUTCOME Trial?
    • Verma, S., Garg, A., Yan, A.T., et al. Effect of empagliflozin on left ventricular mass and diastolic function in individuals with diabetes: an important clue to the EMPA-REG OUTCOME Trial?. Diabetes Care 39 (2016), e212–e213.
    • (2016) Diabetes Care , vol.39 , pp. e212-e213
    • Verma, S.1    Garg, A.2    Yan, A.T.3
  • 37
    • 84975853831 scopus 로고    scopus 로고
    • CV protection in the EMPA-REG OUTCOME Trial: a “thrifty substrate” hypothesis
    • Ferrannini, E., Mark, M., Mayoux, E., CV protection in the EMPA-REG OUTCOME Trial: a “thrifty substrate” hypothesis. Diabetes Care 39 (2016), 1108–1114.
    • (2016) Diabetes Care , vol.39 , pp. 1108-1114
    • Ferrannini, E.1    Mark, M.2    Mayoux, E.3
  • 38
    • 84962439093 scopus 로고    scopus 로고
    • Euglycemic diabetic ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors
    • Rosenstock, J., Ferrannini, E., Euglycemic diabetic ketoacidosis: a predictable, detectable, and preventable safety concern with SGLT2 inhibitors. Diabetes Care 38 (2015), 1638–1642.
    • (2015) Diabetes Care , vol.38 , pp. 1638-1642
    • Rosenstock, J.1    Ferrannini, E.2
  • 39
    • 44449146547 scopus 로고    scopus 로고
    • Diabetes, left ventricular systolic dysfunction, and chronic heart failure
    • MacDonald, M.R., Petrie, M.C., Hawkins, N.M., et al. Diabetes, left ventricular systolic dysfunction, and chronic heart failure. Eur Heart J 29 (2008), 1224–1240.
    • (2008) Eur Heart J , vol.29 , pp. 1224-1240
    • MacDonald, M.R.1    Petrie, M.C.2    Hawkins, N.M.3
  • 40
    • 84992358035 scopus 로고    scopus 로고
    • The cardiovascular biology of glucagon-like peptide-1
    • Drucker, D.J., The cardiovascular biology of glucagon-like peptide-1. Cell Metab 24 (2016), 15–30.
    • (2016) Cell Metab , vol.24 , pp. 15-30
    • Drucker, D.J.1
  • 41
    • 84977480444 scopus 로고    scopus 로고
    • Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial
    • Holman, R.R., Bethel, M.A., George, J., et al. Rationale and design of the EXenatide Study of Cardiovascular Event Lowering (EXSCEL) trial. Am Heart J 174 (2016), 103–110.
    • (2016) Am Heart J , vol.174 , pp. 103-110
    • Holman, R.R.1    Bethel, M.A.2    George, J.3
  • 42
    • 84948740668 scopus 로고    scopus 로고
    • Lixisenatide in patients with type 2 diabetes and acute coronary syndrome
    • Pfeffer, M.A., Claggett, B., Diaz, R., et al., for the ELIXA Investigators. Lixisenatide in patients with type 2 diabetes and acute coronary syndrome. N Engl J Med 373 (2015), 2247–2257.
    • (2015) N Engl J Med , vol.373 , pp. 2247-2257
    • Pfeffer, M.A.1    Claggett, B.2    Diaz, R.3
  • 44
    • 84978884713 scopus 로고    scopus 로고
    • Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people
    • Dinesh Shah, A., Langenberg, C., Rapsomaniki, E., et al. Type 2 diabetes and incidence of a wide range of cardiovascular diseases: a cohort study in 1·9 million people. Lancet, 385(Suppl 1), 2015, S86.
    • (2015) Lancet , vol.385 , pp. S86
    • Dinesh Shah, A.1    Langenberg, C.2    Rapsomaniki, E.3
  • 45
    • 84937216336 scopus 로고    scopus 로고
    • Association of cardiometabolic multimorbidity with mortality
    • Emerging Risk Factors Collaboration. Association of cardiometabolic multimorbidity with mortality. JAMA 314 (2015), 52–60.
    • (2015) JAMA , vol.314 , pp. 52-60
  • 46
    • 84981185386 scopus 로고    scopus 로고
    • Heart failure with preserved ejection fraction: a kidney disorder?
    • Fang, J.C., Heart failure with preserved ejection fraction: a kidney disorder?. Circulation 134 (2016), 435–437.
    • (2016) Circulation , vol.134 , pp. 435-437
    • Fang, J.C.1
  • 47
    • 0033886497 scopus 로고    scopus 로고
    • Glucose and insulin abnormalities relate to functional capacity in patients with congestive heart failure
    • Suskin, N., McKelvie, R.S., Burns, R.J., et al. Glucose and insulin abnormalities relate to functional capacity in patients with congestive heart failure. Eur Heart J 21 (2000), 1368–1375.
    • (2000) Eur Heart J , vol.21 , pp. 1368-1375
    • Suskin, N.1    McKelvie, R.S.2    Burns, R.J.3
  • 48
    • 84982113684 scopus 로고    scopus 로고
    • 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR)
    • Piepoli, M.F., Hoes, A.W., Agewall, S., et al. 2016 European Guidelines on cardiovascular disease prevention in clinical practice: The Sixth Joint Task Force of the European Society of Cardiology and Other Societies on Cardiovascular Disease Prevention in Clinical Practice (constituted by representatives of 10 societies and by invited experts). Developed with the special contribution of the European Association for Cardiovascular Prevention & Rehabilitation (EACPR). Eur Heart J 37 (2016), 2315–2381.
    • (2016) Eur Heart J , vol.37 , pp. 2315-2381
    • Piepoli, M.F.1    Hoes, A.W.2    Agewall, S.3
  • 49
    • 85002833256 scopus 로고    scopus 로고
    • Pharmacologic management of type 2 diabetes: 2016 interim update
    • Canadian Diabetes Association Clinical Practice Guidelines Expert Committee. Pharmacologic management of type 2 diabetes: 2016 interim update. Can J Diabetes 40 (2016), 484–486.
    • (2016) Can J Diabetes , vol.40 , pp. 484-486
  • 50
    • 84883811773 scopus 로고    scopus 로고
    • The cardiovascular safety of incretin-based therapies: a review of the evidence
    • Petrie, J.R., The cardiovascular safety of incretin-based therapies: a review of the evidence. Cardiovasc Diabetol, 12, 2013, 130.
    • (2013) Cardiovasc Diabetol , vol.12 , pp. 130
    • Petrie, J.R.1
  • 51
  • 52
    • 85018315502 scopus 로고    scopus 로고
    • Prognostic implications of biomarker assessments in patients with type 2 diabetes at high cardiovascular risk: a secondary analysis of a randomized clinical trial
    • Scirica, B.M., Bhatt, D.L., Braunwald, E., et al. Prognostic implications of biomarker assessments in patients with type 2 diabetes at high cardiovascular risk: a secondary analysis of a randomized clinical trial. JAMA Cardiol 1 (2016), 989–998.
    • (2016) JAMA Cardiol , vol.1 , pp. 989-998
    • Scirica, B.M.1    Bhatt, D.L.2    Braunwald, E.3
  • 53
    • 84994092361 scopus 로고    scopus 로고
    • Research digest: cardiac biomarkers for risk prediction
    • Preiss, D., Sattar, N., Research digest: cardiac biomarkers for risk prediction. Lancet Diabetes Endocrinol, 4, 2016, 890.
    • (2016) Lancet Diabetes Endocrinol , vol.4 , pp. 890
    • Preiss, D.1    Sattar, N.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.