Effect of intra-articular triamcinolone vs saline on knee cartilage volume and pain in patients with knee osteoarthritis a randomized clinical trial

JAMA - Journal of the American Medical Association

Volumn 317, Issue 19, 2017, Pages 1967-1975

  McAlindon, Timothy E ^a   LaValley, Michael P ^b   Harvey, William F ^a   Price, Lori Lyn ^a,c   Driban, Jeffrey B ^a   Zhang, Ming ^a   Ward, Robert J ^a  

^a TUFTS MEDICAL CENTER   (United States)

^b BOSTON UNIVERSITY SCHOOL OF PUBLIC HEALTH   (United States)

^c TUFTS UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

HEMOGLOBIN A1C; PLACEBO; SODIUM CHLORIDE; TRIAMCINOLONE ACETONIDE; ANTIINFLAMMATORY AGENT; GLUCOCORTICOID; GLYCOSYLATED HEMOGLOBIN; HEMOGLOBIN A1C PROTEIN, HUMAN;

ADULT; ARTICLE; BONE NECROSIS; CARTILAGE DEGENERATION; CARTILAGE FRACTURE; CONTROLLED STUDY; DISEASE SEVERITY ASSESSMENT; DOUBLE BLIND PROCEDURE; DRUG EFFECT; DRUG EFFICACY; DRUG RESPONSE; DRUG WITHDRAWAL; FEMALE; HOT FLUSH; HUMAN; HYPERTENSION; INJECTION SITE PAIN; KELLGREN LAWRENCE GRADE; KNEE CARTILAGE VOLUME; KNEE OSTEOARTHRITIS; KNEE PAIN; LIKERT SCALE; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; MUSCULOSKELETAL SYSTEM PARAMETERS; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; OUTCOME ASSESSMENT; PRIORITY JOURNAL; QUANTITATIVE ANALYSIS; RANDOMIZED CONTROLLED TRIAL; REAL TIME ULTRASOUND SCANNER; RISK BENEFIT ANALYSIS; SIDE EFFECT; SYNOVITIS; TREATMENT DURATION; VISUAL ANALOG SCALE; WESTERN ONTARIO AND MCMASTER UNIVERSITIES OSTEOARTHRITIS INDEX; X RAY SYSTEM; ARTHRALGIA; BLOOD; CARTILAGE; COMPLICATION; DIAGNOSTIC IMAGING; DRUG ADMINISTRATION; DRUG EFFECTS; INTRAARTICULAR DRUG ADMINISTRATION; METABOLISM; OSTEOARTHRITIS, KNEE; PATHOLOGY; SAMPLE SIZE; STATISTICAL MODEL;

ANTI-INFLAMMATORY AGENTS; ARTHRALGIA; CARTILAGE; DOUBLE-BLIND METHOD; DRUG ADMINISTRATION SCHEDULE; FEMALE; GLUCOCORTICOIDS; HEMOGLOBIN A, GLYCOSYLATED; HUMANS; INJECTIONS, INTRA-ARTICULAR; LINEAR MODELS; MAGNETIC RESONANCE IMAGING; MALE; MIDDLE AGED; OSTEOARTHRITIS, KNEE; OUTCOME ASSESSMENT (HEALTH CARE); SAMPLE SIZE; SODIUM CHLORIDE; SYNOVITIS; TRIAMCINOLONE ACETONIDE;

EID: 85019599334     PISSN: 00987484     EISSN: 15383598     Source Type: Journal    
DOI: 10.1001/jama.2017.5283     Document Type: Article

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